lonafarnib has been researched along with baricitinib in 3 studies
| Studies (lonafarnib) | Trials (lonafarnib) | Recent Studies (post-2010) (lonafarnib) | Studies (baricitinib) | Trials (baricitinib) | Recent Studies (post-2010) (baricitinib) |
|---|---|---|---|---|---|
| 224 | 34 | 90 | 653 | 95 | 631 |
| Protein | Taxonomy | lonafarnib (IC50) | baricitinib (IC50) |
|---|---|---|---|
| Cyclin-G-associated kinase | Homo sapiens (human) | 0.136 | |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | 0.1233 | |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | 0.0739 | |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | 0.1565 | |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | 0.4477 | |
| AP2-associated protein kinase 1 | Homo sapiens (human) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laufer, S; Pillaiyar, T | 1 |
| Arnold, R; Djabali, K; Randl, H; Vehns, E | 1 |
| Djabali, K; Hartinger, R; Lattanzi, G; Lederer, EM; Schena, E | 1 |
1 review(s) available for lonafarnib and baricitinib
| Article | Year |
|---|---|
Kinases as Potential Therapeutic Targets for Anti-coronaviral Therapy.
Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Humans; Protein Kinase Inhibitors; SARS-CoV-2; Signal Transduction; Virus Replication | 2022 |
2 other study(ies) available for lonafarnib and baricitinib
| Article | Year |
|---|---|
Baricitinib, a JAK-STAT Inhibitor, Reduces the Cellular Toxicity of the Farnesyltransferase Inhibitor Lonafarnib in Progeria Cells.
Topics: Adolescent; Azetidines; Cells, Cultured; Child, Preschool; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Male; Piperidines; Progeria; Purines; Pyrazoles; Pyridines; STAT1 Transcription Factor; Sulfonamides | 2021 |
Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies.
Topics: Adipogenesis; Humans; Lipodystrophy; Mutation; Progeria | 2023 |