Page last updated: 2024-09-04

lonafarnib and atorvastatin

lonafarnib has been researched along with atorvastatin in 1 studies

Compound Research Comparison

Studies
(lonafarnib)
Trials
(lonafarnib)
Recent Studies (post-2010)
(lonafarnib)
Studies
(atorvastatin)
Trials
(atorvastatin)
Recent Studies (post-2010) (atorvastatin)
22434907,4202,0583,782

Protein Interaction Comparison

ProteinTaxonomylonafarnib (IC50)atorvastatin (IC50)
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.0064
Insulin receptor Rattus norvegicus (Norway rat)0.0002
Prostaglandin G/H synthase 2Homo sapiens (human)0.0002
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0054
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gonzalez, CG; Hernandez, JA; Quintana, AM1

Other Studies

1 other study(ies) available for lonafarnib and atorvastatin

ArticleYear
Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Benzophenones; Body Patterning; Cell Differentiation; Cholesterol; Chondrocytes; Craniofacial Abnormalities; Embryo, Nonmammalian; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Hedgehog Proteins; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Neural Crest; Piperidines; Pyridines; Signal Transduction; Terpenes; Zebrafish; Zebrafish Proteins; Zinc Finger Protein GLI1

2017