lonafarnib has been researched along with a 228839 in 1 studies
| Studies (lonafarnib) | Trials (lonafarnib) | Recent Studies (post-2010) (lonafarnib) | Studies (a 228839) | Trials (a 228839) | Recent Studies (post-2010) (a 228839) |
|---|---|---|---|---|---|
| 224 | 34 | 90 | 5 | 0 | 0 |
| Protein | Taxonomy | lonafarnib (IC50) | a 228839 (IC50) |
|---|---|---|---|
| Chain A, Protein farnesyltransferase alpha subunit | Rattus norvegicus (Norway rat) | 0.0011 | |
| Chain B, Protein farnesyltransferase beta subunit | Rattus norvegicus (Norway rat) | 0.0011 | |
| Chain A, Protein farnesyltransferase alpha subunit | Rattus norvegicus (Norway rat) | 0.0011 | |
| Chain B, Protein farnesyltransferase beta subunit | Rattus norvegicus (Norway rat) | 0.0011 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Bos taurus (cattle) | 0.0011 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 0.0011 | |
| Protein farnesyltransferase subunit beta | Bos taurus (cattle) | 0.0011 | |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, J; Curtin, ML; Florjancic, AS; Frost, DJ; Gu, WZ; Muchmore, SW; Sham, HL | 1 |
1 other study(ies) available for lonafarnib and a 228839
| Article | Year |
|---|---|
Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyltransferase.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Biological Availability; Biphenyl Compounds; Crystallography, X-Ray; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; Half-Life; Imidazoles; Indicators and Reagents; Mice; Models, Molecular; Rats | 2003 |