lomustine and o-(6)-methylguanine

lomustine has been researched along with o-(6)-methylguanine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dolan, ME; Moschel, RC; Pegg, AE1
Dolan, ME; English, HF; Larkin, GL; Pegg, AE1
Clyde, C; Dolan, ME; Erickson, LC; Hora, NK; Norbeck, L; Pegg, AE1
Dolan, ME; Erickson, LC; Hora, NK; Pegg, AE1
Corsico, CD; Dolan, ME; Pegg, AE1

Other Studies

5 other study(ies) available for lomustine and o-(6)-methylguanine

ArticleYear
Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:14

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Drug Synergism; Guanine; Humans; Kidney; Kinetics; Liver; Lomustine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Transplantation, Heterologous

1989
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Line; Cricetinae; Cricetulus; Female; Guanine; Kinetics; Lomustine; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mitoguazone; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transfection

1989
Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
    Cancer research, 1988, Jul-01, Volume: 48, Issue:13

    Topics: Cell Division; Cell Survival; Cross-Linking Reagents; DNA Damage; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1988
Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Cell Division; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Time Factors

1985