lomustine has been researched along with chlorambucil in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (37.93) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Kawase, M; Lorand, T; Perjési, P; Rozmer, Z; Sakagami, H; Stables, JP | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Eriksson, G; Lambert, B | 1 |
| Bringel, C; Jakobsson, PA; Könyves, I; Nordenskjöld, B; Strander, H; Wiman, LG | 1 |
| Dulbecco, R; Rubens, RD; Vaughan-Smith, S | 1 |
| Carey, PJ; Jackson, GH; Lennard, AL; Proctor, SJ | 1 |
| Anderson, JR; Coleman, M; Frizzera, G; Gottlieb, A; Holland, JF; Nissen, NI; Pajak, TF; Propert, KJ; Stutzman, L; Vinciguerra, V | 1 |
| Mödder, B; Ollenschläger, G; Schaefer, HJ | 1 |
| Bosanquet, AG | 1 |
| Bleehen, NM; Honess, DJ | 1 |
| Schein, PS; Tew, KD; Wang, AL | 1 |
| Kehrberg, G; Moldenhauer, H; Rose, H; Saul, G; Wolf, G | 1 |
| Twentyman, PR | 1 |
| Twentyman, P; Workman, P | 1 |
| Gabryś, K; Kotlarek-Haus, S; Potoczek, S | 1 |
| de Pauw, BE; Jongen-Lavrencic, M; Raemaekers, JM; Vreugdenhil, G | 1 |
| Fairey, AF; Jones, HW; Mead, GM; Sweetenham, JW; Whitehouse, JM | 1 |
| Ardiet, C; Lind, MJ | 1 |
| Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D | 1 |
| Apostolidis, J; Foran, JM; Gupta, RK; Kelsey, SM; Lister, TA; Rohatiner, AZ; Shamash, J; Walewski, J; Wilson, AM | 1 |
| Neville, F; Nystrom, ML; Oliver, RT; Shamash, J; Steele, JP | 1 |
| Ansell, W; Barlow, C; Dancey, G; Oliver, RT; Shamash, J; Wilson, P | 1 |
| Berry, WR | 1 |
| Culligan, D; Jackson, GH; Jones, GL; Lennard, AL; Lewis, J; Lucraft, HH; McKay, P; Proctor, SJ; Sieniawski, M; White, J; Wilkinson, J | 1 |
| Horan, M; Maddox, JM; Osborne, W; Shrubsole, C; Tafesh, L | 1 |
5 review(s) available for lomustine and chlorambucil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. General considerations, the nitrosoureas and alkylating agents.
Topics: Alkylation; Antineoplastic Agents; Carmustine; Chlorambucil; Colony-Forming Units Assay; Cyclophosphamide; Drug Storage; Hydrogen-Ion Concentration; Lomustine; Mathematics; Melphalan; Nimustine; Nitrosourea Compounds; Solutions; Temperature; Tumor Stem Cell Assay | 1985 |
[Intensification of cytostatic action by radiosensitizers--a review of the present status of chemosensitization].
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cricetinae; Cyclophosphamide; Doxorubicin; Etanidazole; Lomustine; Melphalan; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents | 1984 |
Pharmacokinetics of alkylating agents.
Topics: Alkylating Agents; Carmustine; Chlorambucil; Cyclophosphamide; Humans; Ifosfamide; Lomustine; Melphalan; Neoplasms; Nitrosourea Compounds; Organophosphorus Compounds; Thiotepa | 1993 |
The role of an all-oral chemotherapy containing lomustine (CCNU) in advanced,fs progressive Hodgkin lymphoma: a patient-friendly palliative option which can result in long-term disease control.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Disease Progression; Dose-Response Relationship, Drug; Etoposide; Hodgkin Disease; Humans; Lomustine; Palliative Care; Patient Satisfaction; Prednisolone; Survival Analysis; Survivors; Time Factors | 2010 |
5 trial(s) available for lomustine and chlorambucil
| Article | Year |
|---|---|
Alternating cycles of combination chemotherapy for patients with recurrent Hodgkin's disease following radiotherapy. A prospectively randomized study by the Cancer and Leukemia Group B.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Clinical Trials as Topic; Doxorubicin; Female; Hodgkin Disease; Humans; Lomustine; Lymph Nodes; Male; Middle Aged; Prednisone; Procarbazine; Prognosis; Random Allocation; Sclerosis; Streptozocin; Vinblastine; Vincristine | 1986 |
Phase-II trial with M-CAVe-CEC as a salvage chemotherapeutic regimen for early relapsed or primary refractory Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Etoposide; Female; Hodgkin Disease; Humans; Lomustine; Male; Methotrexate; Middle Aged; Salvage Therapy; Vinblastine | 1994 |
Low-dose continuous chemotherapy (LBCMVD-56) for refractory and relapsing lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dexamethasone; Drug Administration Schedule; Female; Hodgkin Disease; Hospitalization; Humans; Infusions, Intravenous; Injections, Subcutaneous; Lomustine; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Sepsis; Treatment Outcome; Vincristine | 2000 |
Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Subcutaneous; Lomustine; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Tamoxifen; Time Factors; Treatment Outcome; Vinblastine | 2003 |
Chlorambucil and lomustine (CL56) in absolute hormone refractory prostate cancer: re-induction of endocrine sensitivity an unexpected finding.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Prostatic Neoplasms; Survival Rate | 2005 |
19 other study(ies) available for lomustine and chlorambucil
| Article | Year |
|---|---|
Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells.
Topics: Animals; Antineoplastic Agents; Benzopyrans; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Injections, Intraperitoneal; Leukemia L1210; Mice; Models, Molecular; Molecular Structure; Neoplasms; Neurons; Structure-Activity Relationship; Survival Rate; T-Lymphocytes; Tumor Cells, Cultured | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of cancer chemotherapeutic agents on testicular DNA synthesis in the rat. Evaluation of a short-term test for studies of the genetic toxicity of chemicals and drugs in vivo.
Topics: Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; DNA; Dose-Response Relationship, Drug; Kinetics; Lomustine; Male; Mutation; Procarbazine; Rats; Testis; Thiotepa; Thymidine | 1979 |
Combined treatment of bronchogenic carcinoma with radiotherapy and cytotoxic drugs--a pilot study using prednimustine and chloroethylcyclohexylnitrosurea (CCNU).
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Chlorambucil; Follow-Up Studies; Humans; Lomustine; Lung Neoplasms; Methotrexate; Pilot Projects; Prednisolone; Radiotherapy Dosage; Vincristine | 1978 |
Augmentation of cytotoxic drug action and X-irradiation by antibodies.
Topics: Antibodies, Neoplasm; Antineoplastic Agents; Cell Division; Cell Line; Cell Membrane; Chlorambucil; Clone Cells; Lomustine; Methotrexate; Neoplasms, Experimental; Radiation Effects; Razoxane; Vinblastine | 1975 |
An effective oral combination in advanced relapsed Hodgkin's disease prednisolone, etoposide, chlorambucil and CCNU.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Hematologic Diseases; Hodgkin Disease; Humans; Lomustine; Male; Middle Aged; Prednisolone; Remission Induction | 1990 |
[Oral polychemotherapy in far advanced recurrences of Hodgkin's disease].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Etoposide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Lomustine; Male; Middle Aged; Neoplasm Staging | 1988 |
Thermochemotherapy with cis-platinum, CCNU, BCNU, chlorambucil and melphalan on murine marrow and two tumours: therapeutic gain for melphalan only.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Chlorambucil; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Hyperthermia, Induced; Lomustine; Melphalan; Mice; Mice, Inbred C3H; Neoplasms, Experimental | 1985 |
Alkylating agent interactions with the nuclear matrix.
Topics: Alkylating Agents; Cell Nucleus; Chlorambucil; DNA; HeLa Cells; Humans; Lomustine; Methylnitrosourea; Protein Binding; Ribonucleoproteins; Streptozocin | 1983 |
Modification by WR 2721 of the response to chemotherapy of tumours and normal tissues in the mouse.
Topics: Amifostine; Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Female; Leukocyte Count; Lomustine; Male; Melphalan; Mice; Mice, Inbred C3H; Organothiophosphorus Compounds; Sarcoma, Experimental | 1983 |
Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU.
Topics: Animals; Antineoplastic Agents; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Lethal Dose 50; Leukocyte Count; Lomustine; Male; Melphalan; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental | 1982 |
[Evaluation of early treatment results in Hodgkin's disease during the cytostatic protocol containing methotrexate].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Epirubicin; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Treatment Outcome; Vincristine | 1995 |
CAPE/PALE salvage chemotherapy for Hodgkin's disease patients relapsing within 1 year of ChlVPP chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Lomustine; Male; Middle Aged; Neoplasm Staging; Prednisolone; Procarbazine; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Vinblastine | 1993 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Child, Preschool; Chlorambucil; Cohort Studies; Combined Modality Therapy; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Incidence; Infant; Leukemia, Myeloid; Life Tables; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Podophyllotoxin; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; Risk; Salvage Therapy; Vinblastine; Vincristine | 1999 |
Re-induction of hormonal sensitivity in hormone-refractory prostate cancer--fact or fiction?
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Lomustine; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Prognosis; Prostatic Neoplasms | 2005 |
DECC (dexamethasone, etoposide, chlorambucil, lomustine) as an oral chemotherapy regimen in relapsed and refractory diffuse large B-cell lymphoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dexamethasone; Etoposide; Female; Humans; Lomustine; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Neoplasm Recurrence, Local | 2021 |