loganin has been researched along with iridoids in 130 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.54) | 18.7374 |
| 1990's | 3 (2.31) | 18.2507 |
| 2000's | 34 (26.15) | 29.6817 |
| 2010's | 63 (48.46) | 24.3611 |
| 2020's | 28 (21.54) | 2.80 |
| Authors | Studies |
|---|---|
| Aquino, R; De Simone, F; Pizza, C; Senatore, F | 1 |
| Li, KM; Xie, C; Xu, LZ; Yang, XJ; Yu, MQ | 1 |
| Arvy, MP; Doireau, P; Imbault, N; Naudascher, F; Thiersault, M | 1 |
| Gu, S; Xie, C; Xu, L; Yang, S; Zhang, D | 1 |
| Inoue, K; Katano, N; Ooi, A; Yamamoto, H | 1 |
| Kumar, S; Nautiyal, M; Sati, OP; Sati, S; Semwal, VD; Takeda, Y | 1 |
| Crouch, NP; Hotze, M; Irmler, S; Matern, U; Schmidt, J; Schröder, G; Schröder, J; St-Pierre, B; Strack, D | 1 |
| Jussila, M; Riekkola, ML; Suomi, J; Wiedmer, SK | 1 |
| Iio, R; Inoue, K; Katano, N; Yamamoto, H | 1 |
| Cosson, JP; Magiatis, P; Seguin, E; Skaltsounis, AL; Tillequin, F | 1 |
| Chen, XG; Hu, ZD; Ju, Y; Wang, SF | 1 |
| Ruan, JX; Xie, YS; Zhang, ZQ | 1 |
| Albuquerque, S; Cardona Zuleta, LM; Castro-Gamboa, I; Cavalheiro, AJ; da Silva Bolzani, V; Furlan, M; Marx Young, MC; Siqueira Silva, DH | 1 |
| LEHMANN, H; MERZ, KW | 1 |
| Ren, LM; Wun, JK; Zhang, LT | 1 |
| Guo, JF; Luan, XH; Qiao, SY; Ren, FX; Sun, L; Xiong, SL; Zhang, YX; Zhao, YM | 1 |
| Inoue, K | 1 |
| Ballero, M; Bianco, A; Foddai, S; Guiso, M; Nicoletti, M; Piccin, A; Poli, F; Serafini, M | 1 |
| Gibson, SI; Hong, SB; Peebles, CA; San, KY; Shanks, JV | 1 |
| Lee-Parsons, CW; Royce, AJ | 1 |
| Li, X; Wang, Q; Xu, L; Yin, W; Zhang, L | 1 |
| Gao, CX; Gao, WN; Li, J; Zhang, ZL; Zhao, JY | 1 |
| Bian, J; Chen, HS; Xuan, WD | 1 |
| Chen, J; Li, HJ; Li, P; Qian, ZM; Tang, D | 1 |
| Li, L; Liu, H; Shen, J; Shi, Y; Wei, M; Xu, H | 1 |
| Sun, Y; Wang, Y; Zhao, X | 1 |
| Huo, C; Li, X; Sheng, X; Wang, Q; Zhang, L; Zhang, X | 1 |
| Hao, XJ; Kang, WY | 1 |
| Chen, CC; Chen, CY; Hsu, CY; Liu, HK | 1 |
| Cai, B; Cai, H; Ding, X; Du, W; Wang, M; Yang, H | 1 |
| Hu, ZT; Ji, YB; Li, WL; Wang, XD; Xu, D | 1 |
| Gong, T; Liu, J; Mi, D; Tang, M; Xie, B; Zhang, X; Zhang, Z | 1 |
| Bai, J; Cheng, B; Ji, YB; Li, WL; Sun, Z | 1 |
| Li, LJ; Sun, H; Wang, XJ; Zhang, N | 1 |
| Li, L; Wang, W; Yao, RQ; Zhang, L | 1 |
| Cheng, Y; Liu, ZH; Luo, GA; Meng, XS; Ye, TX; Zhao, HZ | 1 |
| Jang, YP; Kim, SH; Kim, YC; Lee, KY; Oh, TH; Sung, SH | 1 |
| Jang, CG; Kim, HC; Kwon, SH; Lee, SY | 1 |
| Fong, HH; Mesecar, AD; Rong, L; Rothwangl, K; Sabahi, A; Zhang, H | 1 |
| Ma, CJ; Ma, JY; Won, JB | 1 |
| Kang, KS; Noh, JS; Park, CH; Shibahara, N; Tanaka, T; Yamabe, N; Yokozawa, T | 1 |
| Candish, L; Lupton, DW | 2 |
| Chung, JH; Kim, JH; Kim, K; Lee, BY; Lim, KM; Noh, JY; Rhee, HI; Ryu, KH; Um, KA; Yoo, H | 1 |
| Li, M; Sun, H; Wang, P; Wang, W; Wang, X; Yang, K | 1 |
| Hong, SI; Jang, CG; Jung, YH; Kim, HC; Kim, JA; Kwon, SH; Lee, SY | 1 |
| Dai, B; Li, XF; Peng, L; Shen, KJ; Xiao, ZZ; Zhao, J | 1 |
| Ishiguro, K; Iwaoka, E; Ogawa, Y; Oku, H | 1 |
| Chen, Y; Feng, X; Lin, XH; Shan, Y; Sun, MY; Yin, M; Zhao, XZ | 1 |
| Cho, EJ; Kim, JH; Park, CH; Park, JC; Shibahara, N; Tanaka, T; Yokozawa, T | 1 |
| Liebold, T; Rauwald, HW; Straubinger, RK | 1 |
| Hou, J; Jiang, WL; Zhang, SP; Zhu, HB | 1 |
| Jeong, EJ; Kang, SY; Kim, SY; Kim, TB; Kim, YC; Sung, SH; Yang, H | 1 |
| He, JN; Liu, X; Mou, ZL; Zhan, HY; Zhang, ZQ | 1 |
| Chen, SQ; Shang, CL; Wang, LL; Zhang, T | 1 |
| Li, HB; Liu, YC; Yin, ZF; Zhao, GQ | 1 |
| Gu, R; Lai, X; Meng, X; Tan, D; Zhang, Y | 1 |
| Jeong, WS; Jun, M; Youn, K | 1 |
| da Silva, CC; de Carvalho, JE; de Oliveira, CM; de Oliveira, PR; Kato, L; Medina, RP; Santin, SM; Testa, G | 1 |
| Ding, K; Meng, ZG; Shen, Y; Xu, G; Yang, SC; Yang, ZG | 1 |
| Cai, HL; Chen, ML; Li, HD; Li, XL; Tang, HB; Tang, JH; Zhang, LJ | 1 |
| Ismail, I; Jin Kiat, C; Mohamad Zuldin, NN; Mohd Noor, N; Said, IM; Zainal, Z | 1 |
| Fan, H; Gong, N; Ma, AN; Wang, YX; Xiao, Q | 1 |
| Chen, LY; Li, YY; Liu, RH; Wang, YY; Zhang, ZL; Zuo, YM | 1 |
| Jia, ZP; Li, MX; Qiu, JG; Tao, R; Zhang, JH; Zhang, QL | 1 |
| Choi, JS; Jung, HA; Lee, CM; Oh, SH; Park, CH; Tanaka, T; Yokozawa, T | 1 |
| Lee, MK; Liu, B; Liu, K; Lu, C; Lv, G; Lv, X; Wu, Y; Xu, H | 1 |
| Gotfredsen, CH; Gousiadou, C; Jensen, SR; Kokubun, T; Martins, J | 1 |
| Liu, HQ; Wang, TL | 1 |
| Ahn, MR; Ho, CT; Jeong, WS; Jun, M; Kim, H; Kim, OY; Youn, K | 1 |
| Berger, A; Brecker, L; Gastegger, M; Klose, SI; Kostyan, MK; Lorbeer, E; Schinnerl, J | 1 |
| Du, L; Duan, JA; Guo, J; Jiang, S; Liu, P; Qian, D; Shang, EX; Su, SL; Tao, J; Zhao, M | 2 |
| Cheng, CH; Chien, CT; Tsai, WH; Wu, CH | 1 |
| Bianco, A; Casagrande, V; Maggi, A; Serrilli, AM | 1 |
| Bae, GS; Choi, SB; Jo, IJ; Kim, DG; Kim, MJ; Lee, SK; Park, SJ; Shin, JY; Shin, S; Song, HJ | 1 |
| Chen, XF; Cheng, T; Meng, J; Song, JH; Yang, WY; Zeng, Y | 2 |
| Huang, P; Liu, XD; Lu, YH; Ma, M; Peng, XJ; Yuan, LX; Zhou, RB | 1 |
| Feng, M; He, K; Li, X; Song, S; Wang, D; Wang, Y; Ye, X; Zou, Z | 1 |
| Bianco, A; Ornano, L | 1 |
| Bhakta, HK; Choi, JS; Jung, HA; Min, BS; Park, CH; Yokozawa, T | 1 |
| Feng, H; Li, Y; Li, Z; Shen, B; Shi, L; Tian, Y; Zhao, C | 1 |
| Chang, FR; Chen, CS; Jong, YJ; Lo, YC; Tseng, YT | 1 |
| Li, YH; Lin, SL; Liu, CJ; Peng, SX; Shen, YQ; Wang, LF; Xu, YD; Yao, L; Zhao, HD | 1 |
| Han, SM; Hwang, ES; Kim, HB; Kim, MJ; Lee, S; Lee, SO; Maeng, S; Park, JH | 1 |
| Chu, M; Cui, C; Lin, SL; Shen, YQ; Shi, YW; Sun, MF; Xu, YD; Yang, XS; Zhu, YL | 1 |
| Cai, B; Di, L; Du, Y; Hu, L; Li, W; Shi, L; Tao, Y | 1 |
| Chao, G; Cong, F; Ou, X; Song, T; Tian, X; Zhang, W | 1 |
| Du, L; Duan, J; Jiang, S; Qian, D; Tao, J; Zhao, M | 1 |
| Ahn, JH; Hwang, BY; Jo, YH; Kim, SB; Lee, MK; Mo, EJ | 1 |
| Colinas, M; Fuller, VL; Goossens, A; Halkier, BA; Larsen, B; O'Connor, SE; Payne, R; Pollier, J; Schweizer, F; Van Moerkercke, A | 1 |
| Boonyarat, C; Kanokmedhakul, K; Kanokmedhakul, S; Moosophon, P; Plekratoke, K; Suchaichit, N; Suchaichit, NP; Tearavarich, R | 1 |
| Jiang, S; Pu, XL; Tao, JH; Wei, XY; Zhao, M | 1 |
| Babri, S; Farajdokht, F; Mesgari, M; Mohaddes, G; Nayebi Rad, S; Rajabi, M | 2 |
| Li, G; Wang, X; Wang, ZP; Yu, JQ; Zhu, H | 1 |
| Tang, WZ; Wang, LH; Wang, XJ; Xie, BX | 1 |
| Duan, JA; Jiang, S; Tao, JH; Xu, BH; Zhang, W; Zhao, M | 1 |
| Cui, Y; Feng, X; Liu, C; Wang, Y; Zhang, L; Zhao, D | 1 |
| Chen, J; Gao, G; Gao, J; Li, B; Sun, L; Xu, P; Yu, J | 1 |
| Gu, Y; Yang, Y; Zhang, S; Zhao, H | 1 |
| Chen, D; Chen, Q; Du, W; Fu, F; Hu, J; Jin, H; Ruan, H; Tong, P; Wu, C; Wu, J; Yao, S; Yu, H; Zhou, J | 1 |
| Cao, YQ; Jiang, WD; Lu, JG; Pan, YB; Wang, C; Wang, JW; Zhai, WF | 1 |
| Chang, YC; Chen, JY; Cheng, KI; Cheng, YC; Chu, LW; Dai, ZK; Hsu, JH; Wu, BN; Yeh, JL | 1 |
| Cheng, W; Hu, T; Li, X; Ma, Q; Song, G; Yuan, J; Zhang, B; Zhang, G | 1 |
| Chen, J; Chen, Y; Du, Q; Fu, Y; Jiang, M; Jiao, N; Liu, L; Sun, J; Wu, H; Xu, H; Zhu, Y | 2 |
| Ahn, SJ; In, S; Kim, E; Kim, HJ; Lee, A; Min, SS | 1 |
| Chang, YC; Chen, JY; Cheng, YC; Chu, LW; Dai, ZK; Hsieh, SL; Wu, BN | 1 |
| Bao, H; Gong, J; Gong, Y; Hu, L; Li, J; Liu, S; Shen, H; Wang, Z; Zhang, J | 1 |
| Chen, J; Chen, YP; Du, Q; Fu, YX; Gao, YY; Lu, JF; Lv, GH; Lv, X; Shu, AM; Wang, W; Xu, HQ | 1 |
| Guo, KW; Li, L; Luo, Y; Yang, CC; Zhang, L; Zheng, CC | 1 |
| Bae, GS; Choi, JW; Kim, DG; Kim, DU; Kweon, B; Lee, HS; Park, SJ; Shin, JY; Song, HJ; Zhou, Z | 1 |
| Jia, X; Kang, K; Liu, H; Liu, X; Wang, C; Yu, K; Zhang, J | 1 |
| Cho, YY; Choi, N; Jang, JH; Kang, HC; Lee, HS; Lee, JY; Yang, G | 1 |
| Li, X; Wang, C; Wang, H; Xu, J; Yu, K; Zhang, J | 1 |
| Choi, SH; Choi, YH; Jeong, JW; Jeong, SJ; Kim, GY; Kim, SO; Kwon, CY; Lee, H; Noh, JS; Park, C | 1 |
| Huang, F; Wang, X; Xiao, G; Xiao, J | 1 |
| Han, Y; He, J; Pan, CH; Shi, R; Wang, YM; Wang, ZX; Xia, CY; Xu, JK; Yan, Y; Zhang, WK | 1 |
| He, J; Li, L; Lian, WW; Ma, BZ; Xia, CY; Xu, JK; Yan, Y; Zhang, WK | 1 |
| Chang, YC; Chen, SL; Cheng, KI; Cheng, YC; Dai, ZK; Hsu, JH; Lee, CH; Wu, BN; Yeh, JL | 1 |
| Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN | 1 |
| He, K; Li, S; Liu, J; Nie, L; Xiao, S; Xie, F; Xu, J; Yang, C; Yang, X; Zhang, K; Zhou, L; Zou, L | 1 |
| He, J; Li, L; Lian, WW; Peng, Y; Wang, YW; Xia, CY; Xu, JK; Yan, Y; Zhang, F; Zhang, J; Zhang, WK; Zheng, J | 1 |
| Chen, D; Li, C; Wan, H; Yang, Y | 1 |
| Choi, TH; Jeong, SY; Jin, HS; Kim, DW; Kim, J; Lee, CG; Oh, KI; Park, E; Singh, S; Uprety, LP; Yoo, J | 1 |
| Hitora, Y; Hokaguchi, M; Ishikawa, H; Kitajima, M; Kohara, M; Sakamoto, J; Shiomi, S; Tsukamoto, S; Yoshidome, A | 1 |
| Du, G; Gao, W; Guo, Y; He, Y; Luo, D; Pang, X; Shi, J; Xie, X; Xu, W; Yang, X; Zhao, Q; Zhou, Y | 1 |
| Jin, J; Luo, Q; Shi, F | 1 |
2 review(s) available for loganin and iridoids
| Article | Year |
|---|---|
[Cytochrome P450 enzymes in biosyntheses of some plant secondary metabolites].
Topics: Cyclohexanones; Cytochrome P-450 Enzyme System; Glucosides; Indole Alkaloids; Iridoid Glucosides; Iridoids; Naphthoquinones; Oxidation-Reduction; Plants; Secologanin Tryptamine Alkaloids; Tryptamines; Vinca Alkaloids | 2005 |
Phytochemistry, synthesis, analytical methods, pharmacological activity, and pharmacokinetics of loganin: A comprehensive review.
Topics: Cornus; Humans; Iridoids; NF-kappa B; Phosphatidylinositol 3-Kinases; Signal Transduction | 2022 |
128 other study(ies) available for loganin and iridoids
| Article | Year |
|---|---|
Iridoids and secoiridoids from Guettarda platypoda.
Topics: Chemical Phenomena; Chemistry; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Plants, Medicinal; Pyrans | 1988 |
[Determination of loganin in Cornus officinalis Sieb. et Zucc. by TLC scanner].
Topics: Chromatography, Thin Layer; Densitometry; Drugs, Chinese Herbal; Glucosides; Iridoids; Pyrans; Quality Control | 1994 |
2,4-D and alkaloid accumulation in periwinkle cell suspensions.
Topics: 2,4-Dichlorophenoxyacetic Acid; Cells, Cultured; Glucosides; Iridoid Glucosides; Iridoids; Plants, Medicinal; Pyrans; Secologanin Tryptamine Alkaloids; Vinca Alkaloids; Yohimbine | 1994 |
[Determination of loganin in the fruit of Cornus officinalis Sieb. et Zucc].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Glucosides; Iridoids; Magnoliopsida; Pyrans | 1996 |
Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P450.
Topics: Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glucosides; Iridoid Glucosides; Iridoids; Magnoliopsida; Microsomes; NADP; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Pyrans; Substrate Specificity | 2000 |
Iridoid glycosides from Lonicera quinquelocularis.
Topics: Disaccharides; Glucosides; Glycosides; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Roots; Plant Shoots; Plants, Medicinal; Pyrans; Pyrones | 2000 |
Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase.
Topics: Asteraceae; Cells, Cultured; Cloning, Molecular; Cytochrome P-450 Enzyme System; Escherichia coli; Glucosides; Iridoid Glucosides; Iridoids; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Pyrans; Vinca Alkaloids | 2000 |
Determination of iridoid glycosides by micellar electrokinetic capillary chromatography-mass spectrometry with use of the partial filling technique.
Topics: Chromatography, Micellar Electrokinetic Capillary; Glucosides; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Mass Spectrometry; Molecular Structure; Molecular Weight; Plantago; Plants, Medicinal; Pyrans; Scrophulariaceae; Species Specificity; Spectrophotometry, Ultraviolet; Valerianaceae | 2001 |
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.
Topics: Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Glucosides; Iridoids; Ketoconazole; Magnoliopsida; Metyrapone; Miconazole; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Oxygen Consumption; Pyrans | 2001 |
Coelobillardin, an iridoid glucoside dimer from Coelospermum billardieri.
Topics: Acylation; Chromatography; Cyclobutanes; Dimerization; Glucose; Hydrolysis; Iridoids; Methanol; New Caledonia; Nuclear Magnetic Resonance, Biomolecular; Plant Extracts; Rubiaceae; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism | 2002 |
Analysis of three effective components in Fructus corni and its preparations by micellar electrokinetic capillary chromatography.
Topics: Buffers; Chromatography, Micellar Electrokinetic Capillary; Drugs, Chinese Herbal; Electrophoresis, Capillary; Gallic Acid; Iridoids; Molecular Structure; Reproducibility of Results; Temperature | 2003 |
[RP-HPLC determination of loganin in mouse plasma and its pharmacokinetics].
Topics: Adjuvants, Immunologic; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Iridoids; Male; Mice | 2002 |
seco-iridoids from Calycophyllum spruceanum (Rubiaceae).
Topics: Animals; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Magnetic Resonance Spectroscopy; Molecular Structure; Rubiaceae; Stereoisomerism; Trypanocidal Agents; Trypanosoma cruzi | 2003 |
[Loganin. II].
Topics: Iridoids; Strychnine | 1957 |
[Studies on pharmacokinetics of loganin and morroniside in Cornus officinalis injection in mice].
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cornus; Drugs, Chinese Herbal; Female; Injections, Intravenous; Iridoids; Male; Mice; Plants, Medicinal | 2003 |
[Determination of glycosides in traditional Chinese medicine liu-wei di-huang by RP-HPLC].
Topics: Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Cornus; Dioscorea; Drug Combinations; Drugs, Chinese Herbal; Glucosides; Iridoids; Monoterpenes; Plants, Medicinal; Quality Control; Rehmannia | 2003 |
A comparative chemotaxonomic study on Vinca sardoa steam and Vinca difformis pourret.
Topics: Classification; Iridoids; Plant Leaves; Vinca | 2005 |
Effects of terpenoid precursor feeding on Catharanthus roseus hairy roots over-expressing the alpha or the alpha and beta subunits of anthranilate synthase.
Topics: Anthranilate Synthase; Catharanthus; Indole Alkaloids; Iridoid Glucosides; Iridoids; Plant Roots; Tryptamines; Tryptophan; Xylulose | 2006 |
Precursor limitations in methyl jasmonate-induced Catharanthus roseus cell cultures.
Topics: Acetates; Acyclic Monoterpenes; Catharanthus; Cells, Cultured; Cyclopentanes; Iridoids; Oxylipins; Secologanin Tryptamine Alkaloids; Terpenes; Tryptamines | 2006 |
HPLC study of tissue distribution of loganin in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Iridoids; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2006 |
[Function of getting rid of cores of Cornus officinalis Sieb. et Zucc. and studies on method of processing in producing area].
Topics: Chromatography, High Pressure Liquid; Cornus; Drugs, Chinese Herbal; Fruit; Glycosides; Iridoids; Plants, Medicinal; Quality Control; Technology, Pharmaceutical; Time Factors | 2006 |
[A new indole alkaloid glycoside from stems of Nauclea officinalis].
Topics: Carbolines; Glucosides; Glycosides; Indole Alkaloids; Iridoid Glucosides; Iridoids; Molecular Conformation; Molecular Structure; Plant Stems; Plants, Medicinal; Rubiaceae | 2006 |
Simultaneous quantification of seven bioactive components in Caulis Lonicerae Japonicae by high performance liquid chromatography.
Topics: Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Glucosides; Hydroxybenzoates; Iridoid Glucosides; Iridoids; Linear Models; Lonicera; Luteolin; Molecular Structure; Reproducibility of Results; Rutin; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
Morroniside and loganin extracted from Cornus officinalis have protective effects on rat mesangial cell proliferation exposed to advanced glycation end products by preventing oxidative stress.
Topics: Animals; Antioxidants; Cell Cycle; Cell Line; Cell Proliferation; Cell Shape; Cornus; Diabetic Nephropathies; Flow Cytometry; Glutathione Peroxidase; Glycation End Products, Advanced; Glycosides; Iridoids; Malondialdehyde; Mesangial Cells; Microscopy, Fluorescence; Oxidative Stress; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2006 |
Simultaneous determination of four bioactive constituents in Liuwei Dihuang Pills by micellar electrokinetic chromatography.
Topics: Acetonitriles; Benzoates; Boric Acids; Bridged-Ring Compounds; Buffers; Chloramphenicol; Chromatography, Micellar Electrokinetic Capillary; Drug Carriers; Drugs, Chinese Herbal; Glucosides; Glycosides; Humans; Hydrogen-Ion Concentration; Iridoids; Molecular Structure; Monoterpenes; Reference Standards; Reproducibility of Results; Sodium Dodecyl Sulfate; Time Factors | 2007 |
Microbial metabolism of loganin by intestinal bacteria and identification of new metabolites in rat.
Topics: Animals; Bacteria; Chromatography, High Pressure Liquid; Intestines; Iridoids; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2008 |
[Terpenoid glycosides from stem of Luculia pinceana].
Topics: Glucosides; Iridoids; Plant Stems; Plants, Medicinal; Rubiaceae; Saponins | 2007 |
Fructus Corni suppresses hepatic gluconeogenesis related gene transcription, enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Cornus; Dexamethasone; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Fruit; Gene Expression; Gluconeogenesis; Glucose; Humans; Insulin; Insulin-Secreting Cells; Iridoids; Liver; Phosphoenolpyruvate Carboxykinase (ATP); Rats; RNA, Messenger; Triterpenes; Ursolic Acid | 2008 |
Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography.
Topics: Biological Assay; Calibration; Chromatography, High Pressure Liquid; Cornus; Drugs, Chinese Herbal; Furaldehyde; Gallic Acid; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Molecular Structure; Pyrans; Reproducibility of Results; Time Factors | 2008 |
[Studies on absorption mechanism of loganin in intestines of rats].
Topics: Animals; Drugs, Chinese Herbal; Duodenum; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Intestinal Mucosa; Iridoids; Jejunum; Kinetics; Male; Rats; Rats, Wistar | 2008 |
An approach based on HPLC-fingerprint and chemometrics to quality consistency evaluation of Liuwei Dihuang Pills produced by different manufacturers.
Topics: Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Evaluation Studies as Topic; Glucosides; Iridoids; Mass Spectrometry; Medicine, Chinese Traditional; Molecular Structure; Molecular Weight; Monoterpenes; Principal Component Analysis; Quality Control; Spectrometry, Mass, Electrospray Ionization | 2008 |
[Investigation of JinKui ShenQi pills by ultraviolet spectra and tandem mass spectrometry].
Topics: Acetophenones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Iridoids; Principal Component Analysis; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry | 2008 |
[Promoting effect of constituents in plasma after oral administration of liuwei dihuangwan on proliferation of rat osteoblast].
Topics: Administration, Oral; Animals; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Osteoblasts; Plasma; Rats; Rats, Wistar | 2008 |
Cornel iridoid glycoside promotes neurogenesis and angiogenesis and improves neurological function after focal cerebral ischemia in rats.
Topics: Angiogenesis Inducing Agents; Animals; Brain; Cognition; Cornus; Drugs, Chinese Herbal; Glycosides; Infarction, Middle Cerebral Artery; Iridoids; Male; Neurogenesis; Neurons; Neuroprotective Agents; Neuropsychological Tests; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
[Determination of loganin and paeonol in Liuwei Dihuang pills by HPLC amalgamated of double UV waves].
Topics: Acetophenones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Iridoids; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2008 |
Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice.
Topics: Acetylcholinesterase; Administration, Oral; Amnesia; Animals; Avoidance Learning; Behavior, Animal; Cholinesterase Inhibitors; Cognition; Cornus; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Hippocampus; Iridoids; Male; Memory, Short-Term; Mice; Mice, Inbred ICR; Nootropic Agents; Scopolamine; Time Factors | 2009 |
Loganin improves learning and memory impairments induced by scopolamine in mice.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Iridoids; Learning; Male; Maze Learning; Memory Disorders; Mice; Muscarinic Antagonists; Neuroprotective Agents; Scopolamine | 2009 |
Lamiridosins, hepatitis C virus entry inhibitors from Lamium album.
Topics: Antiviral Agents; Hepacivirus; Iridoids; Lamiaceae; Molecular Structure; Plants, Medicinal; Stereoisomerism | 2009 |
Simultaneous determination of four marker components in Yukmijihwang Tang by high performance liquid chromatography/diode array detector.
Topics: Acetophenones; Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Furaldehyde; Glucosides; Iridoids; Medicine, Korean Traditional; Molecular Structure; Monoterpenes; Plant Preparations; Quality Control; Reference Standards; Reproducibility of Results | 2010 |
Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice.
Topics: Animals; Biomarkers; Body Weight; Cholesterol; Cornus; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drinking; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucose; Glycation End Products, Advanced; Hematologic Tests; Inflammation; Iridoids; Kidney; Lipid Metabolism; Liver; Lysine; Male; Mice; Nitric Oxide Synthase Type II; Organ Size; Oxidative Stress; PPAR alpha; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcription Factor RelA; Triglycerides | 2010 |
The total synthesis of (-)-7-deoxyloganin via N-heterocyclic carbene catalyzed rearrangement of α,β-unsaturated enol esters.
Topics: Catalysis; Esters; Heterocyclic Compounds; Iridoids; Methane; Molecular Structure; Stereoisomerism | 2010 |
Anti-inflammatory and analgesic activities of SKLJI, a highly purified and injectable herbal extract of Lonicera japonica.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Enzyme Inhibitors; Hemolysis; Inflammation; Injections, Intravenous; Iridoid Glucosides; Iridoids; Lonicera; Male; Mice; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Sprague-Dawley | 2010 |
The pharmacological effects of morroniside and loganin isolated from Liuweidihuang Wan, on MC3T3-E1 cells.
Topics: 3T3 Cells; Animals; Cell Proliferation; Drugs, Chinese Herbal; Female; Glycosides; Humans; Iridoids; Male; Mice; Osteoporosis, Postmenopausal | 2010 |
Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells.
Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Cytochromes c; Humans; Hydrogen Peroxide; Iridoids; L-Lactate Dehydrogenase; Membrane Potentials; Neuroblastoma; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinases; Reactive Oxygen Species | 2011 |
[Study on the best concentration of combination of the effects of the four original constituents of liu-wei di-huang pill on the proliferation and differentiation of rat preadipocyte].
Topics: Acetophenones; Adipocytes; Animals; Benzoates; Bridged-Ring Compounds; Cell Differentiation; Cell Proliferation; Cells, Cultured; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Fats; Glucosides; Glycosides; Iridoids; Male; Monoterpenes; Plants, Medicinal; Rats; Rats, Wistar | 2010 |
Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica.
Topics: Animals; Anti-Allergic Agents; Chickens; Chlorogenic Acid; Female; Flowers; Hypersensitivity; Iridoid Glucosides; Iridoids; Lonicera; Male; Mice; Mice, Inbred Strains; Muramidase; Phytotherapy; Plant Extracts; Structure-Activity Relationship; Veins | 2011 |
[Studies on the chemical constituents from stems and leaves of Lonicera macranthoides].
Topics: Caffeic Acids; Glycosides; Iridoids; Lonicera; Molecular Structure; Plant Leaves; Plant Stems; Plants, Medicinal; Scopoletin | 2011 |
Hepato-protective effects of loganin, iridoid glycoside from Corni Fructus, against hyperglycemia-activated signaling pathway in liver of type 2 diabetic db/db mice.
Topics: Animals; Cornus; Diabetes Mellitus, Type 2; Hyperglycemia; Iridoid Glycosides; Iridoids; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction | 2011 |
Growth inhibiting activity of lipophilic extracts from Dipsacus sylvestris Huds. roots against Borrelia burgdorferi s. s. in vitro.
Topics: Anti-Bacterial Agents; Borrelia burgdorferi; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Thin Layer; Dipsacaceae; Iridoids; Lipids; Microbial Sensitivity Tests; Plant Extracts; Plant Roots; Solvents; Spectrophotometry, Ultraviolet | 2011 |
Effect of loganin on experimental diabetic nephropathy.
Topics: Animals; Blood Glucose; Cell Line; Cell Proliferation; Connective Tissue Growth Factor; Cornus; Cystatin C; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epithelial Cells; Glucose; Humans; Immunohistochemistry; Iridoids; Kidney; Male; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Weight Gain | 2012 |
Neuroprotective iridoid glycosides from Cornus officinalis fruits against glutamate-induced toxicity in HT22 hippocampal cells.
Topics: Animals; Cell Line, Transformed; Chemical Fractionation; Chromatography, High Pressure Liquid; Cornus; Fruit; Glutamic Acid; Glycosides; Hippocampus; Hydrolysis; Iridoids; Methanol; Mice; Molecular Structure; Neuroprotective Agents; Plant Extracts; Spectrometry, Mass, Electrospray Ionization | 2012 |
Concise formal synthesis of (-)-7-deoxyloganin via N-heterocyclic carbene catalysed rearrangement of α,β-unsaturated enol esters.
Topics: Catalysis; Esters; Glycosylation; Iridoids; Isomerism; Methane; Molecular Structure; Oxidation-Reduction | 2011 |
[Optimization of microwave-assisted extraction with RSM and HPLC determination for three iridoid glycosides in Cornus officinalis].
Topics: Chromatography, High Pressure Liquid; Cornus; Fruit; Glucosides; Iridoid Glucosides; Iridoids; Microwaves; Pyrans; Quality Control; Reproducibility of Results; Solvents | 2011 |
[Study on the correlation between the quality of Cornus officinalis and the contents of the inorganic elements in the planting soil].
Topics: China; Cornus; Fruit; Iridoids; Iron; Manganese; Plants, Medicinal; Polysaccharides; Potassium; Quality Control; Soil; Spectrophotometry, Ultraviolet; Trace Elements; Triterpenes; Ursolic Acid | 2011 |
[Iridoid glycosides from buds of Jasminum officinale L. var. grandiflorum].
Topics: Antiviral Agents; Flowers; Glucosides; Hep G2 Cells; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Inhibitory Concentration 50; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Jasminum; Molecular Structure; Plants, Medicinal | 2011 |
[Determination of loganin in Pterocephalus hookeri by HPLC].
Topics: Chromatography, High Pressure Liquid; Iridoids; Medicine, Tibetan Traditional; Plants, Medicinal | 2011 |
β-Secretase (BACE1) inhibitory property of loganin isolated from Corni fructus.
Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cornus; Enzyme Activation; Iridoids | 2013 |
Cytotoxic activity of Guettarda pohliana Müll. Arg. (Rubiaceae).
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; HT29 Cells; Humans; Iridoid Glucosides; Iridoids; Plant Extracts; Plant Leaves; Plant Roots; Rubiaceae | 2013 |
[Chemical constituents of Dipsacus asper].
Topics: Chromatography, Thin Layer; Dipsacaceae; Iridoids; Plant Roots; Triterpenes | 2012 |
HPLC-DAD method for comprehensive quality control of Semen Strychni.
Topics: Buffers; Calibration; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Iridoids; Limit of Detection; Linear Models; Loganiaceae; Phytotherapy; Plants, Medicinal; Quality Control; Reference Standards; Reproducibility of Results; Seeds; Solvents; Spectrophotometry, Ultraviolet | 2013 |
Induction and analysis of the alkaloid mitragynine content of a Mitragyna speciosa suspension culture system upon elicitation and precursor feeding.
Topics: 2,4-Dichlorophenoxyacetic Acid; Benzyl Compounds; Iridoids; Kinetin; Mitragyna; Naphthaleneacetic Acids; Plant Growth Regulators; Purines; Secologanin Tryptamine Alkaloids; Tissue Culture Techniques; Tryptophan | 2013 |
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Topics: Analgesics; Animals; Central Nervous System Agents; Exenatide; Formaldehyde; Glucagon-Like Peptide-1 Receptor; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; Iridoid Glucosides; Iridoids; Male; Mice; Nociception; PC12 Cells; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, Glucagon; Spinal Cord; Venoms | 2014 |
[Study on chemical constituents of iridoids from eucommiae folium].
Topics: Chromatography, Thin Layer; Coumaric Acids; Eucommiaceae; Iridoids; Molecular Structure; Plant Leaves; Plants, Medicinal | 2014 |
[Isolation and identification of nine iridoid glycosides from Lamiophlomis rotata by HPLC combining PDA and MS].
Topics: Chromatography, High Pressure Liquid; Ethanol; Glucosides; Iridoid Glycosides; Iridoids; Lamiaceae; Molecular Structure; Plant Roots; Plants, Medicinal; Pyrans; Resins, Synthetic; Spectrometry, Mass, Electrospray Ionization; Terpenes | 2014 |
Kinetic and molecular docking studies of loganin and 7-O-galloyl-D-sedoheptulose from Corni Fructus as therapeutic agents for diabetic complications through inhibition of aldose reductase.
Topics: Aldehyde Reductase; Binding Sites; Catalytic Domain; Cornus; Diabetes Complications; Enzyme Inhibitors; Heptoses; Humans; Indicators and Reagents; Iridoids; Kinetics; Models, Molecular; Molecular Conformation; Recombinant Proteins | 2015 |
Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products.
Topics: Analysis of Variance; Animals; Blood Urea Nitrogen; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycation End Products, Advanced; Iridoids; Kidney; Malondialdehyde; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidative Stress; Pancreas; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase | 2015 |
Iridoid glucosides in the endemic Picconia azorica (Oleaceae).
Topics: Azores; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Molecular Structure; Oleaceae; Phenols; Pyrans | 2015 |
[Chemical constituents from flower of Lonicera fragrantissima].
Topics: Caffeic Acids; Chlorogenic Acid; Flavones; Flowers; Glucosides; Inositol; Iridoid Glucosides; Iridoids; Lonicera; Rutin; Sucrose | 2014 |
Neuroprotective effect of loganin against Aβ25-35-induced injury via the NF-κB-dependent signaling pathway in PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Caspase 3; Cell Death; Cyclooxygenase 2; Iridoids; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; PC12 Cells; Peptide Fragments; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Loganin and secologanin derived tryptamine-iridoid alkaloids from Palicourea crocea and Palicourea padifolia (Rubiaceae).
Topics: Costa Rica; Indole Alkaloids; Iridoid Glucosides; Iridoids; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Rubiaceae; Secologanin Tryptamine Alkaloids | 2015 |
Comparative pharmacokinetics of the main compounds of Shanzhuyu extract after oral administration in normal and chronic kidney disease rats.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Cornus; Fruit; Glycosides; Iridoids; Male; Plant Extracts; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Tandem Mass Spectrometry | 2015 |
Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity.
Topics: Animals; Drugs, Chinese Herbal; Female; Intercellular Adhesion Molecule-1; Iridoids; NF-kappa B; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Substance P; Urinary Bladder, Overactive; Urination | 2016 |
Synthesis of deuterium-labelled substrates for the study of oleuropein biosynthesis in Olea europaea callus cultures.
Topics: Deuterium; Iridoid Glucosides; Iridoids; Molecular Structure; Olea; Tissue Culture Techniques | 2016 |
Loganin protects against pancreatitis by inhibiting NF-κB activation.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Female; Iridoids; Mice; Mice, Inbred C57BL; NF-kappa B; Pancreatitis; Protective Agents | 2015 |
[Influences of Base Fertilizer Dosage and Root Size on Quality and Yield of Gentiana crassicaulis Root].
Topics: China; Fertilizers; Gentiana; Iridoid Glucosides; Iridoids; Plant Roots; Plants, Medicinal | 2015 |
[Pharmacokinetics of loganin, ferulic acid and stilbene glucoside in Bushen Tongluo formula in vivo].
Topics: Administration, Oral; Animals; Biological Availability; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Iridoids; Male; Rats; Rats, Sprague-Dawley; Stilbenes | 2015 |
The Hypoglycemic and Synergistic Effect of Loganin, Morroniside, and Ursolic Acid Isolated from the Fruits of Cornus officinalis.
Topics: alpha-Glucosidases; Animals; China; Cornus; Diabetes Mellitus, Experimental; Free Radical Scavengers; Fruit; Glycosides; Hep G2 Cells; Humans; Hypoglycemic Agents; Iridoids; Male; Mice; Plant Extracts; Plants, Medicinal; Reactive Oxygen Species; Triterpenes; Ursolic Acid | 2016 |
Simultaneous determination of loganin, morroniside, catalpol and acteoside in normal and chronic kidney disease rat plasma by UPLC-MS for investigating the pharmacokinetics of Rehmannia glutinosa and Cornus officinalis Sieb drug pair extract.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cornus; Drugs, Chinese Herbal; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Limit of Detection; Male; Mass Spectrometry; Phenols; Rats; Rats, Sprague-Dawley; Rehmannia; Renal Insufficiency, Chronic | 2016 |
Synthesis of LoganVir, a new carbocyclic nucleoside analogue.
Topics: Adenosine; Anti-HIV Agents; Chemistry Techniques, Synthetic; Cyclopentanes; Iridoids; Nucleosides; Reverse Transcriptase Inhibitors; Vinca | 2016 |
Kinetics and molecular docking studies of loganin, morroniside and 7-O-galloyl-D-sedoheptulose derived from Corni fructus as cholinesterase and β-secretase 1 inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Butyrylcholinesterase; Cholinesterase Inhibitors; Cornus; Drug Discovery; Glycosides; Heptoses; Iridoids; Kinetics; Molecular Docking Simulation; Protein Binding | 2016 |
Loganin inhibits the inflammatory response in mouse 3T3L1 adipocytes and mouse model.
Topics: 3T3 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Atherosclerosis; Chemokine CCL2; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Iridoids; Lipid Metabolism; Mice; NF-kappa B; Phosphorylation; Polyethylene Glycols; Signal Transduction; Tumor Necrosis Factor-alpha | 2016 |
Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
Topics: Animals; Apoptosis; Cell Line; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Genetic Predisposition to Disease; Humans; Insulin-Like Growth Factor I; Iridoids; Mice; Mice, Transgenic; Motor Activity; Motor Neurons; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Muscular Atrophy, Spinal; Mutation; Nerve Degeneration; Neuroprotective Agents; Phenotype; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; SKP Cullin F-Box Protein Ligases; Survival of Motor Neuron 1 Protein; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Weight Gain | 2016 |
Unexpected Neuroprotective Effects of Loganin on 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neurotoxicity and Cell Death in Zebrafish.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Iridoids; MAP Kinase Kinase 4; MPTP Poisoning; Neuroprotective Agents; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; TOR Serine-Threonine Kinases; Zebrafish; Zebrafish Proteins | 2017 |
Loganin enhances long-term potentiation and recovers scopolamine-induced learning and memory impairments.
Topics: Analysis of Variance; Animals; Avoidance Learning; Biophysics; Cholinergic Antagonists; Electric Stimulation; Hippocampus; In Vitro Techniques; Iridoids; Learning Disabilities; Long-Term Potentiation; Maze Learning; Memory Disorders; Patch-Clamp Techniques; Rats; Recovery of Function; Scopolamine | 2017 |
Neuroprotective Effects of Loganin on MPTP-Induced Parkinson's Disease Mice: Neurochemistry, Glial Reaction and Autophagy Studies.
Topics: Animals; Astrocytes; Corpus Striatum; Dopamine; Iridoids; Male; Mice; Microglia; MPTP Poisoning; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase | 2017 |
Integrating UHPLC-MS/MS quantification and DAS analysis to investigate the effects of wine-processing on the tissue distributions of bioactive constituents of herbs in rats: Exemplarily shown for Dipsacus asper.
Topics: Animals; Chlorogenic Acid; Chromatography, High Pressure Liquid; Dipsacaceae; Iridoids; Male; Plant Extracts; Plants, Medicinal; Quinic Acid; Rats; Rats, Sprague-Dawley; Saponins; Tandem Mass Spectrometry; Tissue Distribution; Wine | 2017 |
Blocking Smad2 signalling with loganin attenuates SW10 cell cycle arrest induced by TNF-α.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line; E2F1 Transcription Factor; Humans; Inhibitor of Apoptosis Proteins; Iridoids; Real-Time Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Survivin; Tumor Necrosis Factor-alpha | 2017 |
UPLC-Q-TOF/MS-Based Metabolic Profiling Comparison of Two Major Bioactive Components and Their Metabolites in Normal and CKD Rat Plasma, Urine and Feces Following Oral Administration of Fructus Corni Extract.
Topics: Administration, Oral; Animals; Biomarkers; Chromatography, High Pressure Liquid; Cornus; Glycosides; Iridoids; Male; Metabolome; Metabolomics; Plant Extracts; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2017 |
Variation of loganin content in Cornus officinalis fruits at different extraction conditions and maturation stages.
Topics: Chemical Fractionation; Cornus; Fruit; Iridoids | 2017 |
Identification of Iridoid Glucoside Transporters in Catharanthus roseus.
Topics: Animals; Biological Assay; Biological Transport; Biosynthetic Pathways; Catharanthus; Cell Membrane; Gene Expression Regulation, Plant; Iridoid Glucosides; Iridoids; Kinetics; Membrane Transport Proteins; Models, Biological; Oocytes; Plant Proteins; Protein Transport; Terpenes; Xenopus | 2017 |
Phytochemical investigation and acetylcholinesterase inhibitory activity of bark of Hymenodictyon orixense.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Coumarins; Iridoid Glycosides; Iridoids; Phytochemicals; Plant Bark; Plants, Medicinal; Rubiaceae | 2018 |
Comparative metabolism of two major compounds in Fructus Corni extracts by gut microflora from normal and chronic nephropathy rats in vitro by UPLC-Q-TOF/MS.
Topics: Animals; Chromatography, High Pressure Liquid; Cornus; Gastrointestinal Microbiome; Glycosides; Iridoids; Mass Spectrometry; Plant Extracts; Rats; Renal Insufficiency, Chronic | 2018 |
Impact of loganin on pro-inflammatory cytokines and depression- and anxiety-like behaviors in male diabetic rats.
Topics: Animals; Anxiety; Behavior, Animal; Cytokines; Depression; Diabetes Mellitus, Experimental; Iridoids; Male; Rats; Rats, Wistar | 2018 |
[Chemical constituents of Lonicera japonica roots and their anti-inflammatory effects].
Topics: Animals; Anti-Inflammatory Agents; Chlorogenic Acid; Chromatography, High Pressure Liquid; Iridoid Glucosides; Iridoids; Lonicera; Macrophages; Plant Roots; Quinic Acid; Zebrafish | 2016 |
Impact of loganin on pro-inflammatory cytokines and depression- and anxiety-like behaviors in male diabetic rats.
Topics: Animals; Anxiety; Behavior, Animal; Cytokines; Depression; Diabetes Mellitus, Experimental; Interleukin-6; Iridoids; Male; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2018 |
[Study on Chemical Constituents of Strychnos nux-vomica].
Topics: Iridoids; Seeds; Strychnine; Strychnos nux-vomica | 2016 |
[The Effection Study of Transplanting Techniques for Yield and Quality of Gentiana crassicaulis].
Topics: Gentiana; Iridoid Glucosides; Iridoids | 2016 |
UPLC-Q-TOF/MS-based metabolic profiling comparison of four major bioactive components in normal and CKD rat plasma, urine and feces following oral administration of Cornus officinalis Sieb and Rehmannia glutinosa Libosch herb couple extract.
Topics: Administration, Oral; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Cornus; Feces; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Male; Phenols; Plant Extracts; Rats; Rehmannia; Renal Insufficiency, Chronic; Tandem Mass Spectrometry | 2018 |
Loganin prevents BV-2 microglia cells from Aβ
Topics: Amyloid beta-Peptides; Animals; Dinoprostone; Inflammation; Iridoids; Mice; Microglia; NF-kappa B; Nitric Oxide; Peptide Fragments; Signal Transduction; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4 | 2018 |
Established UPLC-MS/MS procedure for multicomponent quantitative analysis in rat plasma: A contrastive pharmacokinetics study of Qiangshen tablet in normal and kidney yang deficiency syndrome models.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Monitoring; Drugs, Chinese Herbal; Ficusin; Furocoumarins; Glucosides; Glycosides; Iridoids; Male; Metabolome; Monoterpenes; Proline; Rats; Rats, Sprague-Dawley; Tablets; Tandem Mass Spectrometry; Yang Deficiency | 2019 |
Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt.
Topics: Animals; Apoptosis; China; Chondrocytes; Inflammation; Interleukin-1beta; Iridoids; Male; Osteoarthritis; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Loganin ameliorates cartilage degeneration and osteoarthritis development in an osteoarthritis mouse model through inhibition of NF-κB activity and pyroptosis in chondrocytes.
Topics: Animals; Chondrocytes; Collagen Type II; Collagen Type X; Cornus; Disease Models, Animal; Fruit; Humans; Iridoids; Male; Menisci, Tibial; Mice; NF-kappa B; Osteoarthritis, Knee; Pyroptosis; Signal Transduction | 2020 |
Loganin alleviates LPS-activated intestinal epithelial inflammation by regulating TLR4/NF-κB and JAK/STAT3 signaling pathways.
Topics: Caco-2 Cells; Cell Survival; Cytokines; Humans; Inflammation; Inflammation Mediators; Insulin-Like Growth Factor I; Intestinal Mucosa; Iridoids; Janus Kinases; Lipopolysaccharides; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Toll-Like Receptor 4 | 2020 |
Loganin prevents chronic constriction injury-provoked neuropathic pain by reducing TNF-α/IL-1β-mediated NF-κB activation and Schwann cell demyelination.
Topics: Analgesics, Non-Narcotic; Animals; Chronic Pain; Constriction; Cytokines; Hyperalgesia; Interleukin-1beta; Iridoids; Male; Neuralgia; NF-kappa B; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Tumor Necrosis Factor-alpha | 2020 |
Protective effects of iridoid glycosides on acute colitis via inhibition of the inflammatory response mediated by the STAT3/NF-кB pathway.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Colitis; Colitis, Ulcerative; Cornus; Dextran Sulfate; Disease Models, Animal; Glycosides; Humans; Iridoid Glycosides; Iridoids; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; NF-kappa B; Phosphorylation; Signal Transduction; STAT3 Transcription Factor | 2020 |
Loganin and catalpol exert cooperative ameliorating effects on podocyte apoptosis upon diabetic nephropathy by targeting AGEs-RAGE signaling.
Topics: Animals; Apoptosis; Diabetic Nephropathies; Drug Therapy, Combination; Glycation End Products, Advanced; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Podocytes; Receptor for Advanced Glycation End Products; Signal Transduction | 2020 |
Loganin alleviates testicular damage and germ cell apoptosis induced by AGEs upon diabetes mellitus by suppressing the RAGE/p38MAPK/NF-κB pathway.
Topics: Animals; Apoptosis; Cell Line; Diabetes Mellitus, Experimental; Down-Regulation; Glycation End Products, Advanced; Inflammation; Iridoids; Kidney; Male; Mice; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protective Agents; Receptor for Advanced Glycation End Products; Signal Transduction; Spermatozoa; Testis | 2020 |
Determination of 12 herbal compounds for estimating the presence of Angelica Gigas Root, Cornus Fruit, Licorice Root, Pueraria Root, and Schisandra Fruit in foods by LC-MS/MS.
Topics: Benzopyrans; Butyrates; Chromatography, Liquid; Coumarins; Cyclooctanes; Dioxoles; Flavanones; Food Analysis; Fruit; Glucosides; Glycosides; Glycyrrhizic Acid; Herbal Medicine; Iridoids; Isoflavones; Lignans; Plant Roots; Plants, Medicinal; Polycyclic Compounds; Tandem Mass Spectrometry | 2020 |
Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation.
Topics: Animals; Glucose; Humans; Inflammasomes; Iridoids; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats; Schwann Cells | 2020 |
Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis.
Topics: Animals; Blotting, Western; Colitis, Ulcerative; Cytokines; Iridoids; Macrophages; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirtuin 1 | 2020 |
Loganin alleviates macrophage infiltration and activation by inhibiting the MCP-1/CCR2 axis in diabetic nephropathy.
Topics: Animals; Chemokine CCL2; Chemokine CCL8; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Glycation End Products, Advanced; Iridoids; Kidney; Macrophage Activation; Macrophages; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Receptors, CCR1; Receptors, CCR2; Signal Transduction; Transforming Growth Factor beta1 | 2021 |
Cornel Iridoid Glycoside Regulates Modification of Tau and Alleviates Synaptic Abnormalities in Aged P301S Mice.
Topics: Administration, Oral; Animals; Brain; Cell-Free System; Disease Models, Animal; Female; Glycosides; Humans; Iridoids; Male; Mice; Mice, Transgenic; Models, Molecular; Molecular Docking Simulation; Mutation; Phenotype; Protein Binding; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; tau Proteins; Tauopathies; Treatment Outcome | 2020 |
Loganin Attenuates the Severity of Acute Kidney Injury Induced by Cisplatin through the Inhibition of ERK Activation in Mice.
Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Cell Death; Cisplatin; Creatinine; Cytokines; Iridoids; Kidney; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL | 2021 |
Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways.
Topics: Acute Kidney Injury; Animals; Cell Line; Cornus; Dose-Response Relationship, Drug; Heme Oxygenase-1; Iridoids; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Molecular Structure; NF-E2-Related Factor 2; Protective Agents; Proto-Oncogene Proteins c-akt; Sepsis; Signal Transduction; Structure-Activity Relationship | 2021 |
Loganin Alleviates Gout Inflammation by Suppressing NLRP3 Inflammasome Activation and Mitochondrial Damage.
Topics: Administration, Oral; Animals; Cells, Cultured; Disease Models, Animal; DNA, Mitochondrial; Gout; Inflammasomes; Inflammation; Iridoids; Macrophages; Male; Mice, Inbred C57BL; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Uric Acid | 2021 |
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Caspase 1; Inflammasomes; Interleukin-1beta; Iridoids; Lung; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; RAW 264.7 Cells; Sepsis | 2021 |
Loganin Inhibits Lipopolysaccharide-Induced Inflammation and Oxidative Response through the Activation of the Nrf2/HO-1 Signaling Pathway in RAW264.7 Macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cell Survival; Dinoprostone; Heme Oxygenase-1; Inflammation; Iridoids; Lipopolysaccharides; Membrane Proteins; Mice; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Phagocytosis; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction | 2021 |
Loganin exerts a protective effect on ischemia-reperfusion-induced acute kidney injury by regulating JAK2/STAT3 and Nrf2/HO-1 signaling pathways.
Topics: Acute Kidney Injury; Animals; Apoptosis; Heme Oxygenase-1; Iridoids; Ischemia; Kidney; Mice; NF-E2-Related Factor 2; Oxidative Stress; Reperfusion; Reperfusion Injury; Signal Transduction | 2022 |
Loganin ameliorates depression-like behaviors of mice via modulation of serotoninergic system.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Iridoids; Mice; Motor Activity; Serotonin | 2021 |
Identifying the mechanism underlying antidepressant-like effects of loganin by network pharmacology in combination with experimental validation.
Topics: Animals; Antidepressive Agents; beta Catenin; Cell Line; Cell Survival; Depression; Inflammation; Iridoids; Lipopolysaccharides; Mice; Microglia; Network Pharmacology; Protein Interaction Maps; Reproducibility of Results; Tumor Necrosis Factor-alpha | 2021 |
Loganin prevents CXCL12/CXCR4-regulated neuropathic pain via the NLRP3 inflammasome axis in nerve-injured rats.
Topics: Animals; Cell Cycle Proteins; Hyperalgesia; Inflammasomes; Iridoids; Neuralgia; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Receptors, CXCR4; Spinal Cord | 2021 |
Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats.
Topics: Animals; Antioxidants; Behavior, Animal; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide; Calcium Channels, T-Type; Cell Line, Tumor; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Fasting; Humans; Hyperglycemia; Inflammation; Inflammation Mediators; Insulin; Insulin Resistance; Iridoids; Male; Neuralgia; Neuroglia; NF-kappa B; Niacinamide; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Dorsal Horn; Streptozocin | 2021 |
Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Iridoids; Mice; Mice, Transgenic; Morris Water Maze Test; Neuroprotective Agents; Proteome | 2021 |
Loganin attenuates interleukin-1
Topics: Animals; Cartilage; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Inflammation; Interleukin-1beta; Interleukin-6; Iridoids; Myeloid Differentiation Factor 88; NF-kappa B; Nitric Oxide; Osteoarthritis; Rats; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Effects of Loganin on Bone Formation and Resorption In Vitro and In Vivo.
Topics: Animals; Female; Iridoids; Mice; Osteoblasts; Osteogenesis; Osteoporosis | 2022 |
Divergent Total Syntheses of Hetero-Oligomeric Iridoid Glycosides.
Topics: Glycosides; Iridoid Glycosides; Iridoids | 2023 |
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Humans; Iridoids; Male; Mice; Mitophagy; Molecular Docking Simulation; Neuroblastoma; Protein Kinases; Ubiquitin-Protein Ligases | 2023 |
Identification of intestinal metabolic activation of loganin generated dialdehyde reactive intermediates improves intestinal bile salt hydrolase activities.
Topics: Activation, Metabolic; Animals; Intestines; Iridoids; Rats | 2023 |