Page last updated: 2024-08-23

lofexidine and naltrexone

lofexidine has been researched along with naltrexone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agren, H1
Dackis, CA; Gold, MS; Washton, AM1
Resnick, RB; Washton, AM1
Greenwood, J; Seivewright, NA1
Gerada, C; Kemp, K; Smith, P1
Bearn, J; Buntwal, N; Gossop, M; Strang, J1
Ali, R; Gowing, L; White, J1
Cubells, JF; Tang, YL; Zhao, C; Zhao, D1
Doebrick, C; Kimmerling, A; Kosten, TR; Sinha, R1
Bramness, J; Gossop, M; Lobmaier, P; Waal, H1
Law, F; Melichar, J; O'Shea, J; Praveen, KT1
Ali, R; Gowing, L; White, JM1
Fogelman, N; Hermes, G; Hyman, SM; Kosten, TR; Sinha, R1

Reviews

8 review(s) available for lofexidine and naltrexone

ArticleYear
Clonidine treatment of the opiate withdrawal syndrome. A review of clinical trials of a theory.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Adrenergic Fibers; Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; Clonidine; Dextropropoxyphene; Drug Therapy, Combination; Heroin Dependence; Humans; Locus Coeruleus; Methadone; Morphine; Naltrexone; Narcotics; Norepinephrine; Rats; Substance Withdrawal Syndrome

1986
The sequential use of clonidine and naltrexone in the treatment of opiate addicts.
    Advances in alcohol & substance abuse, 1984,Spring, Volume: 3, Issue:3

    Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1984
What is important in drug misuse treatment?
    Lancet (London, England), 1996, Feb-10, Volume: 347, Issue:8998

    Topics: Buprenorphine; Clonidine; Humans; Methadone; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders; United Kingdom

1996
An addict who wants to detoxify.
    The Practitioner, 1998, Volume: 242, Issue:1592

    Topics: Acquired Immunodeficiency Syndrome; Adult; Clonidine; Heroin Dependence; Humans; Jaundice; Male; Naltrexone; Needle Sharing; Serologic Tests

1998
Opioid antagonists with minimal sedation for opioid withdrawal.
    The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1

    Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic

2006
Opiate addiction in China: current situation and treatments.
    Addiction (Abingdon, England), 2006, Volume: 101, Issue:5

    Topics: Buprenorphine; China; Clonidine; Drugs, Chinese Herbal; HIV Infections; Humans; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Abuse, Intravenous; Substance Withdrawal Syndrome; Sympatholytics

2006
The pharmacological treatment of opioid addiction--a clinical perspective.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:6

    Topics: Adrenergic Agonists; Analgesics, Opioid; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Social Support; Substance Withdrawal Syndrome

2010
Opioid antagonists with minimal sedation for opioid withdrawal.
    The Cochrane database of systematic reviews, 2017, 05-29, Volume: 5

    Topics: Adrenergic alpha-Agonists; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Non-Randomized Controlled Trials as Topic; Opioid-Related Disorders; Prospective Studies; Randomized Controlled Trials as Topic; Severity of Illness Index; Substance Withdrawal Syndrome

2017

Trials

4 trial(s) available for lofexidine and naltrexone

ArticleYear
Clonidine treatment of the opiate withdrawal syndrome. A review of clinical trials of a theory.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Adrenergic Fibers; Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; Clonidine; Dextropropoxyphene; Drug Therapy, Combination; Heroin Dependence; Humans; Locus Coeruleus; Methadone; Morphine; Naltrexone; Narcotics; Norepinephrine; Rats; Substance Withdrawal Syndrome

1986
Naltrexone and lofexidine combination treatment compared with conventional lofexidine treatment for in-patient opiate detoxification.
    Drug and alcohol dependence, 2000, May-01, Volume: 59, Issue:2

    Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; Neurologic Examination; Opioid-Related Disorders; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome

2000
Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings.
    Psychopharmacology, 2007, Volume: 190, Issue:4

    Topics: Adult; Behavior, Addictive; Clonidine; Cues; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Secondary Prevention; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome

2007
Lofexidine in Combination With Oral Naltrexone for Opioid Use Disorder Relapse Prevention: A Pilot Randomized, Double-Blind, Placebo-Controlled Study.
    The American journal on addictions, 2019, Volume: 28, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Chemoprevention; Clonidine; Craving; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Intention to Treat Analysis; Male; Medication Adherence; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Pilot Projects; Recurrence; Secondary Prevention; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult

2019

Other Studies

2 other study(ies) available for lofexidine and naltrexone

ArticleYear
Recent advances in opiate detoxification: clonidine and lofexidine.
    NIDA research monograph, 1983, Volume: 43

    Topics: Clonidine; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1983
Opioid dependence.
    American family physician, 2012, Sep-15, Volume: 86, Issue:6

    Topics: Buprenorphine; Clonidine; Evidence-Based Medicine; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Prognosis; Risk Factors; Substance Withdrawal Syndrome; Time Factors

2012