Page last updated: 2024-08-23

lofexidine and hydrochlorothiazide

lofexidine has been researched along with hydrochlorothiazide in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexander, N; Maronde, RF; Velasquez, M; Vlachakis, ND1
Lopez, LM; Mehta, JL1
Beitman, RE; Kuzma, RJ; McMahon, FG; Morledge, J; Mroczek, W; Rolf, CN; Tsai, TH1
Graf, E1
Fontaine, R; Friehe, H; Gibson, JP; Larson, EJ; Sells, DM1
Aigner, A; Schmidt, U1
Dustan, HP; Oparil, S; Smith, LR; Wilkins, LH; Winternitz, SR1

Trials

4 trial(s) available for lofexidine and hydrochlorothiazide

ArticleYear
Hemodynamic effect of lofexidine with a diuretic in hypertension.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:6

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isometric Contraction; Male; Middle Aged; Norepinephrine

1983
Comparative efficacy and safety of lofexidine and clonidine given alone or concomitantly with hydrochlorothiazide in hypertensive outpatients.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1982
Lofexidine, a new, antihypertensive imidazoline derivative. Clinical profile of action with single-drug treatment and in combination with hydrochlorothiazide.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Clonidine; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1982
Lofexidine and clonidine in moderate essential hypertension.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:6

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Random Allocation

1981

Other Studies

3 other study(ies) available for lofexidine and hydrochlorothiazide

ArticleYear
Comparative efficacy and safety of lofexidine and clonidine in mild to moderately severe systemic hypertension.
    The American journal of cardiology, 1984, Mar-01, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Random Allocation

1984
Actions of lofexidine on isolated heart and smooth muscle preparations.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Animals; Clonidine; Drug Interactions; Guinea Pigs; Heart; Hydrochlorothiazide; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Vas Deferens

1982
Toxicology of the combination lofexidine/hydrochlorothiazide.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Animals; Clonidine; Dogs; Drug Combinations; Female; Hydrochlorothiazide; Male; Pregnancy; Rats; Rats, Inbred Strains; Teratogens

1982