Page last updated: 2024-08-24

lofentanil and fentanyl

lofentanil has been researched along with fentanyl in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199027 (72.97)18.7374
1990's6 (16.22)18.2507
2000's3 (8.11)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cometta-Morini, C; Kamal, J; Loew, G; Maguire, P; Tsai, N; Upton, C1
Cesselin, F; De Witte, PA; Hamon, M; Laduron, PM; Levy, C; Mauborgne, A1
Donnerer, J; Lembeck, F1
Janssen, PF; Laduron, PM3
De Witte, PA; Laduron, PM1
Janssen, PF; Laduron, PM; Poncet, J1
Lüllmann, H; Martins, BS; Peters, T1
Bilsback, P; Rolly, G; Tampubolon, O1
Korinek, AM1
Durant, PA; Yaksh, TL1
Durant, PA; Noueihed, RY; Yaksh, TL1
Brase, DA1
Janssen, PA; Lu, HR; Meert, TF; van Craenndonck, H1
Gamse, R; Saria, A1
Poncet, J; Reny-Palasse, V; Rips, R1
Cross, G; West, CD; Wood, S; Wootton, R1
Amann, R; Barthó, L; Lembeck, F; Saria, A; Szolcsányi, J1
Camu, F; Van den Abeele, G1
Leysen, J; Niemegeers, CJ; Pace, NL; Stanley, TH1
Borel, JD1
Laduron, PM2
Heykants, JJ; Hurkmans, RM; Meuldermans, WE1
Gommeren, W; Leysen, JE1
Gommeren, W; Ilien, B; Laduron, PM; Leysen, JE1
Balasubramanian, V; Burns, HD; Dannals, RF; Duelfer, T; Frost, JJ; Langström, B; Ravert, HT; Wagner, HN1
Tung, AS; Yaksh, TL1
Chen, C; Claude, PA; Law, PY; Liu-Chen, LY; Luo, LY; Xue, JC; Yin, J; Zhu, J1
Butour, JL; Meunier, JC; Moisand, C; Mollereau, C; Parmentier, M1
Butour, JL; Mazarguil, H; Meunier, JC; Moisand, C; Mollereau, C1
Blake, AD; Bot, G; Li, S; Reisine, T1
Acosta-Burruel, M; Espitia, SA; Hawkinson, JE1
Cao, Y; Chen, KX; Huang, XQ; Ji, RY; Jiang, HL; Luo, XM; Zhu, YC1
David Clark, J; Demirci, H; Gharagozlou, P; Lameh, J1
Ellis, CR; Hawkins, EG; Kim, MT; Kruhlak, NL; Stavitskaya, L1

Trials

1 trial(s) available for lofentanil and fentanyl

ArticleYear
Efficacy of the extradural administration of lofentanil, buprenorphine or saline in the management of postoperative pain. A double-blind study.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic; Double-Blind Method; Epidural Space; Female; Fentanyl; Humans; Injections; Male; Middle Aged; Morphinans; Pain, Postoperative

1985

Other Studies

36 other study(ies) available for lofentanil and fentanyl

ArticleYear
Pharmacological profiles of fentanyl analogs at mu, delta and kappa opiate receptors.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens

1992
Ethanol and opiate decrease the axonal transport of substance-P like immunoreactive material in rat vagus-nerves.
    Neuropeptides, 1990, Volume: 16, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Animals; Axons; Benzimidazoles; Biological Transport; Choice Behavior; Drinking; Ethanol; Fentanyl; Ligation; Male; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Substance P; Time Factors; Vagus Nerve

1990
Opioid control of the function of primary afferent substance P fibres.
    European journal of pharmacology, 1985, Aug-27, Volume: 114, Issue:3

    Topics: Afferent Pathways; Animals; Electric Stimulation; Enkephalins; Fentanyl; In Vitro Techniques; Naloxone; Perfusion; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vasodilation

1985
Impaired axonal transport of opiate and muscarinic receptors in streptozocin-diabetic rats.
    Brain research, 1986, Aug-20, Volume: 380, Issue:2

    Topics: Animals; Axonal Transport; Diabetes Mellitus, Experimental; Fentanyl; Male; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Opioid; Sciatic Nerve; Streptozocin; Time Factors; Vagus Nerve

1986
Enhanced axonal transport of receptor-bound opiate in ethanol-treated rats.
    Neuroscience letters, 1987, Jun-26, Volume: 77, Issue:3

    Topics: Animals; Axonal Transport; Ethanol; Fentanyl; Male; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Opioid

1987
Retrograde axonal transport of receptor-bound opiate in the vagus and delayed accumulation in the nodose ganglion.
    Brain research, 1985, May-06, Volume: 333, Issue:2

    Topics: Animals; Axonal Transport; Capsaicin; Fentanyl; Male; Nodose Ganglion; Rats; Rats, Inbred Strains; Receptors, Opioid; Vagus Nerve; Vinblastine

1985
Opiate receptors in brain labelled in vivo with [3H]lofentanil.
    Neuropharmacology, 1985, Volume: 24, Issue:7

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Fentanyl; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Subcellular Fractions

1985
pH-dependent accumulation of fentanyl, lofentanil and alfentanil by beating guinea pig atria.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Alfentanil; Analgesics, Opioid; Animals; Fentanyl; Guinea Pigs; Heart Atria; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardial Contraction; Myocardium; Time Factors

1985
[Use of morphine derivatives by the systemic route in the treatment of acute pain].
    Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:5

    Topics: Acute Disease; Alfentanil; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Infusions, Parenteral; Intraoperative Period; Pain; Postoperative Period; Sufentanil

1985
Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study.
    Anesthesiology, 1986, Volume: 64, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Behavior, Animal; Bupivacaine; Catheterization; Catheters, Indwelling; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Epidural Space; Fentanyl; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Time Factors

1986
Studies of the pharmacology and pathology of intrathecally administered 4-anilinopiperidine analogues and morphine in the rat and cat.
    Anesthesiology, 1986, Volume: 64, Issue:1

    Topics: Alfentanil; Analgesia; Analgesics, Opioid; Animals; Catheterization; Cats; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Humans; Injections, Spinal; Morphine; Motor Activity; Naloxone; Rats; Spinal Cord; Sufentanil; Time Factors

1986
Unequal opiate cross-tolerance to morphine in the locomotor-activation model in the mouse.
    Neuropharmacology, 1986, Volume: 25, Issue:3

    Topics: Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Receptors, Opioid; Time Factors

1986
Comparison between epidural fentanyl, sufentanil, carfentanil, lofentanil and alfentanil in the rat: analgesia and other in vivo effects.
    European journal of anaesthesiology, 1988, Volume: 5, Issue:5

    Topics: Alfentanil; Analgesia, Epidural; Analgesics, Opioid; Animals; Fentanyl; Male; Rats; Rats, Inbred Strains; Sufentanil

1988
Antidromic vasodilatation in the rat hindpaw measured by laser Doppler flowmetry: pharmacological modulation.
    Journal of the autonomic nervous system, 1987, Volume: 19, Issue:2

    Topics: Adrenergic Fibers; Animals; Capsaicin; Cimetidine; Electric Stimulation; Enkephalin, Methionine; Female; Fentanyl; Hindlimb; Lasers; Male; Naloxone; Pyrilamine; Rats; Regional Blood Flow; Rheology; Skin; Vasodilation

1987
TRH-induced antinociception: interaction with the opioid systems?
    General pharmacology, 1987, Volume: 18, Issue:2

    Topics: Analgesia; Animals; Brain; Cyclazocine; Endorphins; Ethylketocyclazocine; Fentanyl; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Thyrotropin-Releasing Hormone

1987
An analgesiometry system for use in rabbits with some preliminary data on the effects of buprenorphine and lofentanil.
    Laboratory animals, 1988, Volume: 22, Issue:3

    Topics: Analgesia; Animals; Buprenorphine; Female; Fentanyl; Injections, Subcutaneous; Kinetics; Male; Pain Measurement; Rabbits; Rectum

1988
Peripheral effects of opioid drugs on capsaicin-sensitive neurones of the guinea-pig bronchus and rabbit ear.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Bronchi; Capsaicin; Ear, External; Enkephalin, Methionine; Female; Fentanyl; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Narcotics; Neurons; Pain; Rabbits

1987
Clinical evaluation of the analgesic potency of lofentanil in postoperative pain.
    Acta anaesthesiologica Belgica, 1983, Volume: 34, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Humans; Isonipecotic Acids; Male; Middle Aged; Pain, Postoperative; Pirinitramide; Time Factors

1983
Narcotic dosage and central nervous system opiate receptor binding.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:8

    Topics: Analgesia; Analgesics, Opioid; Anesthesia; Animals; Central Nervous System; Dose-Response Relationship, Drug; Fentanyl; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sufentanil

1983
New narcotics in anesthesia.
    Contemporary anesthesia practice, 1983, Volume: 7

    Topics: Alfentanil; Analgesics, Opioid; Animals; Cardiovascular System; Dogs; Fentanyl; Humans; Respiration; Sufentanil

1983
Axoplasmic transport and possible recycling of opiate receptors labelled with 3H-lofentanil.
    Life sciences, 1982, Aug-02, Volume: 31, Issue:5

    Topics: Animals; Axonal Transport; Fentanyl; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors; Vagus Nerve

1982
Axonal transport of opiate receptors in capsaicin-sensitive neurones.
    Brain research, 1984, Feb-27, Volume: 294, Issue:1

    Topics: Animals; Axonal Transport; Capsaicin; Fentanyl; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance P; Vagus Nerve

1984
Axonal transport of receptors: coexistence with neurotransmitter and recycling.
    Biochemical pharmacology, 1984, Mar-15, Volume: 33, Issue:6

    Topics: Animals; Axonal Transport; Capsaicin; Dogs; Dopamine beta-Hydroxylase; Fentanyl; Humans; Neurotransmitter Agents; Norepinephrine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Sciatic Nerve; Vagus Nerve

1984
Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and lofentanil in blood.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 257, Issue:1

    Topics: Alfentanil; Animals; Blood Proteins; Fentanyl; Humans; In Vitro Techniques; Male; Orosomucoid; Protein Binding; Rats; Rats, Inbred Strains; Sufentanil

1982
Binding properties of 3H-lofentanil at the opiate receptor.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 258, Issue:1

    Topics: Animals; Brain; Fentanyl; In Vitro Techniques; Kinetics; Rats; Receptors, Opioid; Stereoisomerism

1982
Solubilized opiate receptors labelled with 3H-lofentanil.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 258, Issue:2

    Topics: Animals; Brain; Fentanyl; In Vitro Techniques; Lysophosphatidylcholines; Microsomes; Rats; Receptors, Opioid; Solubility

1982
In vivo studies of opiate receptors.
    Annals of neurology, 1984, Volume: 15 Suppl

    Topics: Brain; Carbon Radioisotopes; Diprenorphine; Drug Compounding; Fentanyl; Humans; Radioactive Tracers; Receptors, Opioid; Structure-Activity Relationship; Tomography, Emission-Computed

1984
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
    Pain, 1982, Volume: 12, Issue:4

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Nociceptors; Pain; Reflex; Skin; Time Factors

1982
The region in the mu opioid receptor conferring selectivity for sufentanil over the delta receptor is different from that over the kappa receptor.
    FEBS letters, 1996, Apr-15, Volume: 384, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Diprenorphine; Fentanyl; Kinetics; Protein Binding; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Sufentanil

1996
Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids.
    FEBS letters, 1996, Oct-14, Volume: 395, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Diprenorphine; Dynorphins; Etorphine; Fentanyl; Glutamine; Histamine; Humans; Kinetics; Ligands; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid

1996
Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids.
    European journal of pharmacology, 1997, Feb-19, Volume: 321, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Analgesics, Opioid; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Enzyme Inhibitors; Fentanyl; Molecular Sequence Data; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid

1997
Fentanyl and its analogs desensitize the cloned mu opioid receptor.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Analgesics, Opioid; Animals; Cells, Cultured; Cyclic AMP; Fentanyl; Mice; Mutagenesis; Receptors, Opioid, mu; Sufentanil; Transfection

1998
Opioid activity profiles indicate similarities between the nociceptin/orphanin FQ and opioid receptors.
    European journal of pharmacology, 2000, Feb-18, Volume: 389, Issue:2-3

    Topics: Animals; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Narcotics; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid

2000
Study on mechanism of interaction of nociceptin and opioids binding with opioid receptor-like 1 receptor.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:6

    Topics: Binding Sites; Drug Interactions; Etorphine; Fentanyl; Models, Molecular; Molecular Conformation; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid

2000
Activity of opioid ligands in cells expressing cloned mu opioid receptors.
    BMC pharmacology, 2003, Jan-04, Volume: 3

    Topics: Azocines; beta-Endorphin; Binding, Competitive; Butorphanol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fentanyl; Humans; Hydromorphone; Ligands; Morphine; Naltrexone; Phenazocine; Radioligand Assay; Receptors, Opioid, mu; Tritium

2003
Predicting opioid receptor binding affinity of pharmacologically unclassified designer substances using molecular docking.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Binding Sites; Fentanyl; Humans; Kinetics; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Receptors, Opioid, mu; Thermodynamics

2018