Compounds > loe 908
Page last updated: 2024-09-03

loe 908 and wortmannin

loe 908 has been researched along with wortmannin in 4 studies

Compound Research Comparison

Studies
(loe 908)		Trials
(loe 908)		Recent Studies (post-2010)
(loe 908)		Studies
(wortmannin)		Trials
(wortmannin)		Recent Studies (post-2010) (wortmannin)
50054,0662726

Protein Interaction Comparison

ProteinTaxonomyloe 908 (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, N; Kawanabe, Y; Masaki, T4

Other Studies

4 other study(ies) available for loe 908 and wortmannin

ArticleYear
Effects of phosphoinositide 3-kinase on the endothelin-1-induced activation of voltage-independent Ca(2+) channels and mitogenesis in Chinese hamster ovary cells stably expressing endothelin(a) receptor.
    Molecular pharmacology, 2002, Volume: 62, Issue:3

    Topics: Acetamides; Androstadienes; Animals; Calcium; Calcium Channels; CHO Cells; Chromones; Cricetinae; Drug Interactions; Endothelin-1; Enzyme Inhibitors; Imidazoles; Isoquinolines; Morpholines; Phosphatidylinositol 3-Kinases; Receptor, Endothelin A; Receptors, Endothelin; Transfection; Wortmannin

2002
Role of phosphoinositide 3-kinase in the nonselective cation channel activation by endothelin-1/endothelinB receptor.
    American journal of physiology. Cell physiology, 2003, Volume: 284, Issue:2

    Topics: Acetamides; Androstadienes; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Membrane; CHO Cells; Chromones; Cricetinae; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Ion Channels; Isoquinolines; Morpholines; Phosphatidylinositol 3-Kinases; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Up-Regulation; Wortmannin

2003
Involvements of voltage-independent Ca2+ channels and phosphoinositide 3-kinase in endothelin-1-induced PYK2 tyrosine phosphorylation.
    Molecular pharmacology, 2003, Volume: 63, Issue:4

    Topics: Acetamides; Androstadienes; Animals; Calcium; Calcium Channels; Cells, Cultured; Chromones; Drug Interactions; Endothelin-1; Enzyme Inhibitors; Focal Adhesion Kinase 2; Imidazoles; Isoquinolines; Morpholines; Muscle, Smooth, Vascular; Nifedipine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Wortmannin

2003
Effects of phosphoinositide 3-kinase on endothelin-1-induced activation of voltage-independent Ca2+ channels and vasoconstriction.
    Biochemical pharmacology, 2004, Jul-15, Volume: 68, Issue:2

    Topics: Acetamides; Androstadienes; Animals; Basilar Artery; Calcium; Calcium Channels; Chromones; Drug Interactions; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Isoquinolines; Morpholines; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Rabbits; Vasoconstriction; Wortmannin

2004