Compounds > loe 908
Page last updated: 2024-09-03

loe 908 and verapamil

loe 908 has been researched along with verapamil in 2 studies

Compound Research Comparison

Studies
(loe 908)		Trials
(loe 908)		Recent Studies (post-2010)
(loe 908)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
500517,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomyloe 908 (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inagaki, R; Muramatsu, I; Suzuki, F; Takauji, R; Taniguchi, T1
Brady, JD; Jezior, JR; McCammon, KA; Miner, AS; Ratz, PH; Rosenstein, DI1

Other Studies

2 other study(ies) available for loe 908 and verapamil

ArticleYear
[Two-phase responses of acid expulsion triggered by alpha-1a adrenoceptor in CHO cell].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114 Suppl 1

    Topics: Acetamides; Acids; Amiloride; Animals; Calcium Channel Blockers; CHO Cells; Conotoxins; Cricetinae; Egtazic Acid; Humans; Imidazoles; Isoquinolines; Nifedipine; Norepinephrine; Receptors, Adrenergic, alpha; Verapamil

1999
Dependency of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetamides; Amides; Animals; Bethanechol; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Isoquinolines; Muscle Contraction; Myosin Light Chains; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rabbits; Time Factors; Urinary Bladder; Verapamil

2001