Page last updated: 2024-09-03

loe 908 and thapsigargin

loe 908 has been researched along with thapsigargin in 7 studies

Compound Research Comparison

Studies
(loe 908)
Trials
(loe 908)
Recent Studies (post-2010)
(loe 908)
Studies
(thapsigargin)
Trials
(thapsigargin)
Recent Studies (post-2010) (thapsigargin)
50055,2343918

Protein Interaction Comparison

ProteinTaxonomyloe 908 (IC50)thapsigargin (IC50)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)0.002

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Birke, FW; Encabo, A; Groschner, K; Kukovetz, WR; Romanin, C1
Enoki, T; Furutani, H; Hasegawa, H; Hashimoto, N; Ishikawa, M; Iwamuro, Y; Masaki, T; Minowa, T; Miwa, S; Okamoto, Y; Okazawa, M; Zhang, XF1
Igarashi, T; Imai, T; Otsuka, K; Shigenobu, K; Takayanagi, K; Tanaka, H; Tanaka, Y; Yamaki, F1
Iwamuro, Y; Lee, K; Miwa, S; Morita, H; Okamoto, Y; Zhang, XF1
Enoki, T; Hashimoto, N; Kawanabe, Y; Masaki, T; Okamoto, Y1
Bootman, MD; Holmes, AM; McDonald, F; Roderick, HL1
Ambily, A; Authi, KS; Chamberlain, EV; Gibbins, JM; Jones, CI; Kaiser, WJ; Kassouf, N; Li, Z; Pierro, C1

Other Studies

7 other study(ies) available for loe 908 and thapsigargin

ArticleYear
Inhibition of a store-operated Ca2+ entry pathway in human endothelial cells by the isoquinoline derivative LOE 908.
    British journal of pharmacology, 1996, Volume: 119, Issue:4

    Topics: Acetamides; Calcium; Calcium Channels; Cells, Cultured; Endothelium, Vascular; Humans; Ionomycin; Isoquinolines; Membrane Potentials; Thapsigargin

1996
Activation of three types of voltage-independent Ca2+ channel in A7r5 cells by endothelin-1 as revealed by a novel Ca2+ channel blocker LOE 908.
    British journal of pharmacology, 1999, Volume: 126, Issue:5

    Topics: Acetamides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cations; Cells, Cultured; Drug Interactions; Endothelin-1; Imidazoles; Ionomycin; Isoquinolines; Patch-Clamp Techniques; Rats; Thapsigargin

1999
Comparison of the Ca2+ entry channels responsible for mechanical responses of guinea-pig aorta to noradrenaline and thapsigargin using SK&F 96365 and LOE 908.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:2

    Topics: Acetamides; Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cytoplasm; Enzyme Inhibitors; Extracellular Space; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Thapsigargin; Type C Phospholipases

2000
Failure of endothelin-1 to activate store-operated Ca2+ channels by lack of mobilization from intracellular Ca2+ stores in cultured bovine adrenal chromaffin cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:1

    Topics: Acetamides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cattle; Cells, Cultured; Chromaffin Cells; Endothelin-1; Enzyme Inhibitors; Imidazoles; Ion Channels; Isoquinolines; Thapsigargin

2001
Ca(2+) channels activated by endothelin-1 in CHO cells expressing endothelin-A or endothelin-B receptors.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:5

    Topics: Acetamides; Adenosine Triphosphatases; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; CHO Cells; Cricetinae; Electrophysiology; Endothelin-1; Enzyme Inhibitors; Imidazoles; Inositol Phosphates; Isoquinolines; Patch-Clamp Techniques; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Thapsigargin

2001
Interaction between store-operated and arachidonate-activated calcium entry.
    Cell calcium, 2007, Volume: 41, Issue:1

    Topics: Acetamides; Arachidonic Acid; Calcium Channels; Calcium Signaling; Cell Line; Cytosol; Humans; Imidazoles; Isoquinolines; Nitric Oxide; Thapsigargin

2007
The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets.
    Cellular signalling, 2014, Volume: 26, Issue:3

    Topics: Acetamides; Actins; Anilides; Antibodies; Blood Platelets; Calcium; Calcium Signaling; Collagen; Endoplasmic Reticulum; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; Humans; Ion Channels; Isoquinolines; Membrane Proteins; Myosins; Neoplasm Proteins; Platelet Activation; Platelet Aggregation; Protein Binding; Stromal Interaction Molecule 1; Thapsigargin; Thiadiazoles; Thrombosis; Thrombospondin 1

2014