lodenosine has been researched along with dideoxyadenosine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 15 (62.50) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T | 1 |
| Aoki, S; Broder, S; Driscoll, JS; Ford, H; Johns, DG; Kelley, JA; Marquez, VE; Mitsuya, H; Roth, JS; Tseng, CK | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R | 1 |
| Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV | 1 |
| Balzarini, J; De Clercq, E; Knispel, T; Marquez, VE; Meier, C; Siddiqui, MA | 1 |
| Gao, YG; Liaw, YC; Marquez, VE; Wang, AH | 1 |
| Driscoll, JS; Gao, WY; Johns, DG; Mitsuya, H | 1 |
| Adelsberger, J; Baseler, M; Boyle, MJ; Connors, M; Davey, RT; Flanigan, ME; Ford, H; Geiger, SP; Lane, HC | 1 |
| Ahluwalia, GS; Cooney, DA; Driscoll, JS; Johns, DG; Mitsuya, H; Shirasaka, T | 1 |
| Ahluwalia, GS; Cooney, DA; Driscoll, JS; Johns, DG; Mitsuya, H | 1 |
| Campbell, DA; Shah, VR; Shyu, WC; Srinivas, NR | 1 |
| Boudinot, FD; Chu, CK; Cretton-Scott, E; Kotra, LP; Koudriakova, T; Manouilov, KK; Schinazi, RF; Shanmuganathan, K; Sommadossi, JP | 1 |
| Driscoll, JS; Fridland, A; Hui, FK; Kavlick, MF; Mitsuya, H; Srinivas, RV; Tanaka, M; Ueno, T | 1 |
| Ford, H; Kelley, JA; Mitsuya, H; Roth, JS; Tanaka, M | 1 |
| Balis, FM; Kelley, JA; McCully, CM; Poplack, DG; Roth, JS | 1 |
| Anderson, L; Barchi, JJ; Ford, H; Knispel, T; Kodama, E; Le, R; Marquez, VE; Meier, C; Mitsuya, H; Mu, L; Nicklaus, MC; Russ, P; Sarafianos, SG; Siddiqui, MA | 1 |
| Kelley, JA; Roth, JS; Wang, J | 1 |
| Ford, H; Kelley, JA; Roth, JS; Zhang, H | 1 |
| Hanna, L | 1 |
| Aboul-Enein, HY; Abu-Zaid, S | 1 |
| Hirose, N; Izawa, K; Katayama, S; Maruyama, T; Naito, M; Takamatsu, S | 1 |
| Anderson, BD; DeGraw, RT | 2 |
24 other study(ies) available for lodenosine and dideoxyadenosine
| Article | Year |
|---|---|
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship | 1991 |
Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV.
Topics: Antiviral Agents; Drug Stability; Gene Products, gag; HIV; HIV Core Protein p24; Lymphocyte Activation; Purine Nucleosides; Viral Core Proteins | 1990 |
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
Topics: Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; HIV; Structure-Activity Relationship | 1987 |
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine | 1994 |
cycloSal-Pronucleotides of 2'-fluoro-ara- and 2'-fluoro-ribo-2',3'- dideoxyadenosine as a strategy to bypass a metabolic blockade.
Topics: 3T3 Cells; Adenosine Deaminase; AMP Deaminase; Animals; Anti-HIV Agents; Cell Line; Dideoxyadenosine; Drug Delivery Systems; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Organophosphates; Prodrugs; Structure-Activity Relationship; Virus Replication | 1999 |
Molecular structures of two new anti-HIV nucleoside analogs: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine and 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)hypoxanthine.
Topics: Antiviral Agents; Didanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; X-Ray Diffraction | 1992 |
Enhancement by hydroxyurea of the anti-human immunodeficiency virus type 1 potency of 2'-beta-fluoro-2',3'-dideoxyadenosine in peripheral blood mononuclear cells.
Topics: Antiviral Agents; Cells, Cultured; Dideoxyadenosine; Drug Synergism; HIV Core Protein p24; HIV-1; Humans; Hydroxyurea; Monocytes | 1995 |
The human HIV/peripheral blood lymphocyte (PBL)-SCID mouse. A modified human PBL-SCID model for the study of HIV pathogenesis and therapy.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antiviral Agents; Base Sequence; CD4-Positive T-Lymphocytes; Dideoxyadenosine; Disease Models, Animal; DNA Primers; DNA, Viral; Genes, env; HIV Infections; HIV-1; Humans; Immunotherapy, Adoptive; Lymphocyte Count; Lymphocyte Transfusion; Male; Mice; Mice, SCID; Molecular Sequence Data; Proviruses; Transplantation, Heterologous; Tumor Necrosis Factor-alpha; Viremia | 1995 |
Enhancement by 2'-deoxycoformycin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of 2',3'-dideoxyadenosine and 2'-beta-fluoro-2',3'-dideoxyadenosine.
Topics: Adenosine Deaminase Inhibitors; Cell Line; Didanosine; Dideoxyadenosine; Drug Synergism; HIV; IMP Dehydrogenase; Pentostatin; Phosphorylation; Ribavirin | 1994 |
Enhanced stimulation by ribavirin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of purine 2'-beta-fluoro-2',3'-dideoxynucleosides.
Topics: Didanosine; Dideoxyadenosine; Dideoxynucleosides; Drug Synergism; HIV-1; Phosphorylation; Purine Nucleosides; Ribavirin; Structure-Activity Relationship | 1993 |
High-performance liquid chromatographic analysis of 2'-fluoro-2',3'-dideoxyadenosine and 2'-fluoro-2',3'-dideoxyinosine in dog plasma and urine.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxyadenosine; Dogs; Male | 1996 |
In vitro and in vivo evaluation of 6-azido-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosylpurine and N6-methyl-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosyladenine as prodrugs of the anti-HIV nucleosides 2'-F-ara-ddA and 2'-F-ara-ddI.
Topics: Animals; Anti-HIV Agents; Azides; Biotransformation; Didanosine; Dideoxyadenosine; Female; Magnetic Resonance Spectroscopy; Mice; Microsomes, Liver; Prodrugs; Spectrophotometry, Ultraviolet; Vidarabine | 1996 |
In vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosine.
Topics: Animals; Anti-HIV Agents; COS Cells; Deoxyadenine Nucleotides; Dideoxyadenosine; Dideoxynucleotides; Drug Resistance, Microbial; Genes, pol; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 1997 |
Determination of 2'-beta-fluoro-2',3'-dideoxyadenosine, an experimental anti-AIDS drug, in human plasma by high-performance liquid chromatography.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Blood Proteins; Chromatography, High Pressure Liquid; Dideoxyadenosine; Drug Stability; HIV; HIV Seropositivity; Humans; Protein Binding; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1998 |
2'-beta-fluoro-2',3'-dideoxyadenosine, lodenosine, in rhesus monkeys: plasma and cerebrospinal fluid pharmacokinetics and urinary disposition.
Topics: Animals; Anti-HIV Agents; Dideoxyadenosine; Macaca mulatta; Male | 1999 |
Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase.
Topics: Anti-HIV Agents; Binding Sites; Deoxyadenine Nucleotides; Dideoxyadenosine; Dideoxynucleotides; Dinucleoside Phosphates; HIV Reverse Transcriptase; Humans; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Reverse Transcriptase Inhibitors; Thermodynamics; Tyrosine | 2000 |
Determination of lodenosine and its major metabolite in human plasma by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Dideoxyadenosine; Humans; Molecular Structure; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2000 |
Evaluation of a fluorogenic derivatization method for the reversed-phase HPLC analysis of 2'-beta-fluoro-2',3'-dideoxyadenosine, a new anti-AIDS drug.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Dideoxyadenosine; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2001 |
FddA: antiretroviral in development.
Topics: Anti-HIV Agents; Clinical Trials, Phase I as Topic; Dideoxyadenosine; Drug Stability; Drugs, Investigational; HIV Infections; Humans | 1998 |
High performance liquid chromatography analysis of 9-(2',3'-dideoxy-2'beta-fluoro-D-threo-penta furanosyl) adenine and its metabolite in human plasma using solid-phase extraction on a polyfluorinated reversed stationary phase.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Dideoxyadenosine; Fluorine; Humans; Spectrophotometry, Ultraviolet | 2001 |
Synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine (FddA) via a purine 3'-deoxynucleoside.
Topics: Anti-HIV Agents; Deoxyadenosines; Dideoxyadenosine; Molecular Conformation | 2001 |
Enhanced oral bioavailability of 2'- beta-fluoro-2',3'-dideoxyadenosine (F-ddA) through local inhibition of intestinal adenosine deaminase.
Topics: Adenine; Adenosine Deaminase Inhibitors; Algorithms; Animals; Anti-HIV Agents; Biological Availability; Biological Transport; Chemical Phenomena; Chemistry, Physical; Dideoxyadenosine; Enzyme Inhibitors; Intestinal Absorption; Intestines; Male; Rats; Rats, Sprague-Dawley | 2001 |
Lodenosine trial halted.
Topics: Clinical Trials as Topic; Dideoxyadenosine; Humans | 2000 |
Determination of carrier-mediated transport of 2',3'-dideoxypurine nucleosides in the rat ileum using a bidirectional perfusion technique.
Topics: Animals; Biological Transport; Didanosine; Dideoxyadenosine; Drug Carriers; Ileum; Intestinal Absorption; Male; Perfusion; Permeability; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |