Compounds > locustamyoinhibiting-peptide--locusta-migratoria

locustamyoinhibiting-peptide--locusta-migratoria and neomyosuppressin

locustamyoinhibiting-peptide--locusta-migratoria has been researched along with neomyosuppressin* in 1 studies

Other Studies

1 other study(ies) available for locustamyoinhibiting-peptide--locusta-migratoria and neomyosuppressin

Article	Year
Isolation, primary structure and synthesis of neomyosuppressin, a myoinhibiting neuropeptide from the grey fleshfly, Neobellieria bullata. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 102, Issue:2 1. An amidated decapeptide, showing strong inhibitory activity of spontaneous visceral muscle movement was isolated, from head extracts of 42 thousand fleshflies, Neobellieria bullata (Diptera, Sarcophagidae). 2. Amino acid sequencing and verification by peptide synthesis revealed the following primary structure: Thr-Asp-Val-Asp-His-Val-Phe-Leu-Arg-PheNH2. 3. The novel peptide was termed neomyosuppressin or Neb-MS. 4. During the process of consecutive high performance liquid chromatography (HPLC) purifications the biological activity of the samples was monitored using heterologous bioassay system. 5. The threshold level of synthetic Neb-MS was found to be 8.6 +/- 0.5 x 10(-11) M on the Leucophaea hindgut and 3.4 +/- 0.5 x 10(-10) M on the Locusta oviduct bioassay, respectively. Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Diptera; Dose-Response Relationship, Drug; Female; Grasshoppers; Insect Hormones; Insect Proteins; Male; Molecular Sequence Data; Muscle Contraction; Neuropeptides	1992

Article

Year

Isolation, primary structure and synthesis of neomyosuppressin, a myoinhibiting neuropeptide from the grey fleshfly, Neobellieria bullata.

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 102, Issue:2

1. An amidated decapeptide, showing strong inhibitory activity of spontaneous visceral muscle movement was isolated, from head extracts of 42 thousand fleshflies, Neobellieria bullata (Diptera, Sarcophagidae). 2. Amino acid sequencing and verification by peptide synthesis revealed the following primary structure: Thr-Asp-Val-Asp-His-Val-Phe-Leu-Arg-PheNH2. 3. The novel peptide was termed neomyosuppressin or Neb-MS. 4. During the process of consecutive high performance liquid chromatography (HPLC) purifications the biological activity of the samples was monitored using heterologous bioassay system. 5. The threshold level of synthetic Neb-MS was found to be 8.6 +/- 0.5 x 10(-11) M on the Leucophaea hindgut and 3.4 +/- 0.5 x 10(-10) M on the Locusta oviduct bioassay, respectively.

Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Diptera; Dose-Response Relationship, Drug; Female; Grasshoppers; Insect Hormones; Insect Proteins; Male; Molecular Sequence Data; Muscle Contraction; Neuropeptides

1992