Compounds > lobeline

lobeline and lobelane

lobeline has been researched along with lobelane in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chagkutip, J; Crooks, PA; Dwoskin, LP; Nickell, JR; Vartak, AP1
Crooks, PA; Deaciuc, AG; Dwoskin, LP; Grinevich, VP; Hojahmat, M; Horton, DB; Miller, DK; Norrholm, SD1
Crooks, PA; Deaciuc, AG; Dwoskin, LP; Zheng, G3
Crooks, PA; Deaciuc, G; Dwoskin, LP; Krishnamurthy, S; Nickell, JR; Norrholm, S; Siripurapu, KB; Zheng, G1
Crooks, PA; Dwoskin, LP; Gabriela Deaciuc, A; Vartak, AP1
Crooks, PA; Deaciuc, AG; Dwoskin, LP; Nickell, JR; Zheng, G1
Crooks, PA; Deaciuc, AG; Ding, D; Dwoskin, LP; Nickell, JR; Penthala, NR1
Crooks, PA; Dwoskin, LP; Nickell, JR; Siripurapu, KB; Vartak, A1
Crooks, PA; Dwoskin, LP; Janganati, V; Joolakanti, SR; Nickell, JR; Zheng, G1
Crooks, PA; Culver, JP; Dwoskin, LP; Janganati, V; Nickell, JR; Zheng, G1
Damaj, MI; Dukat, M; Flammia, D; Glennon, RA; Martin, B1
Crooks, PA; Deaciuc, AG; Dwoskin, LP; Norrholm, SD; Zheng, G1
Crooks, PA; Culver, JP; Deaciuc, AG; Dwoskin, LP; Horton, DB; Nickell, JR; Penthala, NR; Zheng, G1
Crooks, PA; Dwoskin, LP; Hankosky, ER; Janganati, V; Joolakanti, SR; Nickell, JR1

Reviews

1 review(s) available for lobeline and lobelane

ArticleYear
The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.
    Advances in pharmacology (San Diego, Calif.), 2014, Volume: 69

    Topics: Amphetamine-Related Disorders; Animals; Drug Delivery Systems; Drug Discovery; Humans; Lobeline; Methamphetamine; Protein Binding; Treatment Outcome; Vesicular Monoamine Transport Proteins

2014

Other Studies

15 other study(ies) available for lobeline and lobelane

ArticleYear
Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2).
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Binding Sites; Lobeline; Protein Binding; Pyrrolidines; Structure-Activity Relationship; Tetrabenazine; Vesicular Monoamine Transport Proteins

2009
Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.
    Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2

    Topics: Animals; Esters; Ligands; Lobeline; Male; Molecular Structure; Neurons; Neurotransmitter Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

2010
Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2.
    Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24

    Topics: Animals; Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Kinetics; Lobeline; Models, Chemical; Oxygen; Piperidines; Rats; Structure-Activity Relationship; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2008
Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Evaluation, Preclinical; Lobeline; Male; Methamphetamine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Synaptic Vesicles; Synaptosomes; Vesicular Monoamine Transport Proteins

2010
Quinlobelane: a water-soluble lobelane analogue and inhibitor of VMAT2.
    Bioorganic & medicinal chemistry letters, 2010, Jun-15, Volume: 20, Issue:12

    Topics: Animals; Binding Sites; Dopamine; Humans; Hydrogenation; Hydroquinones; Lobelia; Lobeline; Methamphetamine; Solubility; Structure-Activity Relationship; Substance-Related Disorders; Synaptic Vesicles; Vesicular Monoamine Transport Proteins

2010
Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues.
    The Journal of organic chemistry, 2009, Aug-21, Volume: 74, Issue:16

    Topics: Animals; Binding Sites; Cyclooctanes; Lobeline; Molecular Conformation; Rats; Stereoisomerism; Vesicular Monoamine Transport Proteins

2009
Phenyl ring-substituted lobelane analogs: inhibition of [³H]dopamine uptake at the vesicular monoamine transporter-2.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:3

    Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Lobeline; Male; Protein Binding; Protein Transport; Rats; Rats, Sprague-Dawley; Tritium; Vesicular Monoamine Transport Proteins

2011
Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake.
    Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

    Topics: Animals; Azetidines; Dopamine; Dopamine Uptake Inhibitors; Isomerism; Kinetics; Lobeline; Protein Binding; Rats; Synaptic Vesicles; Tritium; Vesicular Monoamine Transport Proteins

2013
Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
    Bioorganic & medicinal chemistry letters, 2016, 05-15, Volume: 26, Issue:10

    Topics: Chemistry Techniques, Synthetic; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Evaluation, Preclinical; Lobeline; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Vesicular Monoamine Transport Proteins

2016
1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.
    Bioorganic & medicinal chemistry letters, 2016, 07-01, Volume: 26, Issue:13

    Topics: Animals; Binding Sites; Brain; Drug Design; Lobeline; Piperidines; Radioligand Assay; Rats; Structure-Activity Relationship; Vesicular Monoamine Transport Proteins

2016
Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding.
    Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18

    Topics: Analgesics; Animals; Brain; Lobeline; Piperidines; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Structure-Activity Relationship

1999
Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.
    Journal of medicinal chemistry, 2005, Aug-25, Volume: 48, Issue:17

    Topics: Animals; Brain; In Vitro Techniques; Ligands; Lobeline; Membrane Glycoproteins; Membrane Transport Proteins; Radioligand Assay; Rats; Stereoisomerism; Structure-Activity Relationship; Synaptic Vesicles; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2005
Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands.
    Bioorganic & medicinal chemistry letters, 2005, Oct-15, Volume: 15, Issue:20

    Topics: Animals; Ligands; Protein Binding; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Tropanes

2005
Exploring the effect of
    MedChemComm, 2013, Volume: 4, Issue:3

    Topics:

2013
Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [
    Bioorganic & medicinal chemistry letters, 2017, 12-15, Volume: 27, Issue:24

    Topics: Dopamine; Dopamine Plasma Membrane Transport Proteins; ERG1 Potassium Channel; Humans; Kinetics; Piperazines; Piperidines; Protein Binding; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Vesicular Monoamine Transport Proteins

2017