Compounds > lnd 623
Page last updated: 2024-09-03

lnd 623 and ouabain

lnd 623 has been researched along with ouabain in 4 studies

Compound Research Comparison

Studies
(lnd 623)		Trials
(lnd 623)		Recent Studies (post-2010)
(lnd 623)		Studies
(ouabain)		Trials
(ouabain)		Recent Studies (post-2010) (ouabain)
80016,35772747

Protein Interaction Comparison

ProteinTaxonomylnd 623 (IC50)ouabain (IC50)
STAT3, partialHomo sapiens (human)1.154
Kruppel-like factor 5Homo sapiens (human)0.0832
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-1 Rattus norvegicus (Norway rat)4.3
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.17
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.031
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)1.1263
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.1646
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.097
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.8
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Rattus norvegicus (Norway rat)0.0018
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0031

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LaBella, FS; Sashi Kumar, VP; Smyth, DD; Templeton, JF; Widajewicz, W; Yan, Y1
Berrebi-Bertrand, I; Lelievre, LG; Maixent, JM1
Brown, L1
Berrebi-Bertrand, I; Lelièvre, L; Maixent, JM1

Other Studies

4 other study(ies) available for lnd 623 and ouabain

ArticleYear
Digitaloid pregnanes promote potassium-sparing diuresis in the guinea pig.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:5

    Topics: Animals; Cardiotonic Agents; Diuresis; Glucosides; Guinea Pigs; Kidney; Male; Mannosides; Medroxyprogesterone; Medroxyprogesterone Acetate; Ouabain; Potassium; Pregnanes; Radioligand Assay; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship

1992
Inhibition of cardiac (Na+, K+)-ATPase isozymes by LND 623.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Animals; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Isoenzymes; Mannosides; Myocardium; Ouabain; Pregnanes; Rats; Sodium-Potassium-Exchanging ATPase

1991
Positive inotropic and vasoconstrictor responses to 14 beta-aminopregnane derivatives in isolated tissues from the guinea-pig.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:8

    Topics: Animals; Aorta, Thoracic; Cardiotonic Agents; Guinea Pigs; Male; Mannosides; Myocardial Contraction; Ouabain; Papillary Muscles; Pregnanes; Steroids; Vasoconstriction; Vasoconstrictor Agents

1990
Mechanism underlying the strong positive inotropic effects of LND-623: specific inhibition of Na, K-ATPase isoforms and exclusion of cellular sites of contractile control.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:6

    Topics: Adenylyl Cyclases; Animals; Cardiotonic Agents; Dogs; Erythrocytes; Humans; In Vitro Techniques; Isoenzymes; Male; Mannosides; Membranes; Myocardial Contraction; Myofibrils; Ouabain; Phosphoric Diester Hydrolases; Pregnanes; Rats; Rats, Wistar; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase

1998