Compounds > lnd 623
Page last updated: 2024-09-03

lnd 623 and digoxin

lnd 623 has been researched along with digoxin in 3 studies

Compound Research Comparison

Studies
(lnd 623)		Trials
(lnd 623)		Recent Studies (post-2010)
(lnd 623)		Studies
(digoxin)		Trials
(digoxin)		Recent Studies (post-2010) (digoxin)
80011,4839581,289

Protein Interaction Comparison

ProteinTaxonomylnd 623 (IC50)digoxin (IC50)
STAT3, partialHomo sapiens (human)1.862
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)0.32
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)0.0055
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.19
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiaris (dog)0.5
Nuclear receptor ROR-gammaHomo sapiens (human)3.4798
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0055
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.2359

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berrebi Bertrand, I; Fénard, S; Lelièvre, LG; Maixent, JM1
Biour, M; Cheymol, G; Heckle, J; Jaillon, P; Jarreau, FX; Poirier, JM; Weissenburger, J1
Fenard, S; Jarreau, FX; Koenig, JJ1

Other Studies

3 other study(ies) available for lnd 623 and digoxin

ArticleYear
Efficacy and safety of the novel Na+,K(+)-ATPase inhibitor 20R 14 beta-amino 3 beta-rhamnosyl 5 beta-pregnan 20 beta-ol in a dog model of heart failure.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:11

    Topics: Anesthesia; Animals; Cardiotonic Agents; Digoxin; Dogs; Female; Heart Failure; Hemodynamics; Male; Mannosides; Myocardial Contraction; Pregnanes; Propranolol; Sodium-Potassium-Exchanging ATPase

1992
Comparative hemodynamic study of a new aminosteroid: LND-623 with its 20 alpha-isomer: LND-369, and with digoxin and digoxigenin-rhamnoside in the anesthetized dog.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Cardiac Output; Digoxigenin; Digoxin; Dogs; Glycosides; Heart Rate; Hemodynamics; Isomerism; Mannosides; Myocardial Contraction; Pregnanes; Renin

1989
A new inotropic aminosteroid: LND 623.
    European heart journal, 1984, Volume: 5 Suppl F

    Topics: Animals; Cardiotonic Agents; Digoxin; Dogs; Dose-Response Relationship, Drug; Glycosides; Guinea Pigs; Heart; Male; Mannosides; Myocardial Contraction; Papillary Muscles; Pregnanes; Propranolol; Reserpine; Stimulation, Chemical; Structure-Activity Relationship

1984