lm 4108 has been researched along with indomethacin in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crews, BC; Kalgutkar, AS; Kozak, KR; Marnett, AB; Marnett, LJ; Remmel, RP; Rowlinson, SW | 1 |
| Crews, BC; Kalgutkar, AS; Marnett, AB; Marnett, LJ; Remmel, RP | 1 |
| Blobaum, AL; Marnett, LJ | 1 |
| Algutkar, AS; Crews, BC; Kalgutkar, AS; Kozak, KR; Marnett, LJ; Remmel, RP | 1 |
| Babaev, VR; Burleigh, ME; Crews, BC; Fazio, S; Linton, MF; Marnett, LJ; Morrow, JD; Oates, JA; Patel, MB; Remmel, RP | 1 |
| Bauman, JN; Boyer, D; Kalgutkar, AS; Kapinos, B; Karki, K; Walker, DP | 1 |
1 review(s) available for lm 4108 and indomethacin
| Article | Year |
|---|---|
Structural and functional basis of cyclooxygenase inhibition.
Topics: Animals; Cardiovascular System; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Kinetics; Models, Molecular; Protein Conformation; Risk Assessment | 2007 |
5 other study(ies) available for lm 4108 and indomethacin
| Article | Year |
|---|---|
Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Edema; Esters; Gastrointestinal Diseases; Hindlimb; Humans; Indomethacin; Isoenzymes; Kinetics; Macrophages; Male; Meclofenamic Acid; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sheep | 2000 |
Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Indomethacin; Isoenzymes; Macrophages; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Sheep; Structure-Activity Relationship | 2000 |
Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.
Topics: Animals; Bile; Biotransformation; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Indomethacin; Injections, Intravenous; Isoenzymes; Mass Spectrometry; Membrane Proteins; Mice; Microsomes, Liver; Prostaglandin-Endoperoxide Synthases; Rats; Recombinant Proteins; Species Specificity | 2004 |
Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Indomethacin; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Thromboxanes | 2005 |
Utility of MetaSite in improving metabolic stability of the neutral indomethacin amide derivative and selective cyclooxygenase-2 inhibitor 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-phenethyl-acetamide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biotransformation; Computer Simulation; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Indomethacin; Male; Mass Spectrometry; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2009 |