ll-z1640-2 and formal-glycol

ll-z1640-2 has been researched along with formal-glycol* in 1 studies

Other Studies

1 other study(ies) available for ll-z1640-2 and formal-glycol

Article	Year
Total synthesis of TAK-kinase inhibitor LL-Z1640-2 via consecutive macrocyclization and transannular aromatization. Organic letters, 2010, Dec-03, Volume: 12, Issue:23 The biomimetic total synthesis of LL-Z1640-2 (3) is reported without the use of phenol protection. The aromatic unit was constructed via the transannular aromatization of macrocyclic triketo-ester 2, which in turn was synthesized by macrolactonization using an intramolecular trapping of a triketo-ketene derived from dioxinone 1. Topics: Cyclization; Dioxolanes; Lactones; MAP Kinase Kinase Kinases; Molecular Structure; Protein Kinase Inhibitors	2010

Article

Year

Total synthesis of TAK-kinase inhibitor LL-Z1640-2 via consecutive macrocyclization and transannular aromatization.

Organic letters, 2010, Dec-03, Volume: 12, Issue:23

The biomimetic total synthesis of LL-Z1640-2 (3) is reported without the use of phenol protection. The aromatic unit was constructed via the transannular aromatization of macrocyclic triketo-ester 2, which in turn was synthesized by macrolactonization using an intramolecular trapping of a triketo-ketene derived from dioxinone 1.

Topics: Cyclization; Dioxolanes; Lactones; MAP Kinase Kinase Kinases; Molecular Structure; Protein Kinase Inhibitors

2010