Page last updated: 2024-08-25

ljc 10627 and imipenem, anhydrous

ljc 10627 has been researched along with imipenem, anhydrous in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	29 (55.77)	18.2507
2000's	13 (25.00)	29.6817
2010's	8 (15.38)	24.3611
2020's	2 (3.85)	2.80

Authors

Authors	Studies
Katakami, M; Miyake, Y; Murakami, K; Ono, T; Susilowati, H; Viducic, D	1
Lombardo, F; Obach, RS; Waters, NJ	1
Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A	1
Eto, M; Ishii, Y; Mano, Y; Tateda, K; Yamaguchi, K	1
Abendroth, J; Atkins, K; Boyer, SH; Clifton, MC; Dudley, MN; Durso, S; Griffith, DC; Hecker, SJ; Hirst, GC; King, P; Lomovskaya, O; Loutit, JS; Morgan, EE; Potts, KT; Raymond, A; Reddy, KR; Sabet, M; Sun, D; Tarazi, Z; Totrov, M; Tsivkovski, R	1
Ichihara, Y; Mikami, Y; Miyaji, M; Nishimura, C; Ohashi, S; Yazawa, K	1
Furukawa, Y; Hikida, M; Kawashima, K; Kuwao, S; Nishiki, K; Nishizawa, K; Saito, I	1
Jacobus, NV; Petersen, PJ; Testa, RT; Weiss, WJ	1
Furukawa, Y; Hikida, M; Konno, M; Mitsuhashi, S; Nishiki, K; Tashiro, K; Ubukata, K; Yoshida, M	1
Mitsuhashi, S; Yoshida, M	1
Bland, S; Dubreuil, L; Grollier, G; Houcke, I; Mory, F; Sedallian, A	1
Amicosante, G; Felici, A; Franceschini, N; Galleni, M; Oratore, A; Perilli, M; Segatore, B; Setacci, D; Stefani, S	1
Hikida, M; Kawashima, K; Mitsuhashi, S; Nishiki, K; Yamazaki, Y; Yoshida, M	1
Bremner, DA; Raymond, NJ	1
Lahnborg, G; Nord, CE	1
Day, IP; Goudie, J; Nishiki, K; Williams, PD	1
Andrews, JM; Boswell, FJ; Gill, MJ; Wise, R	1
Bhachech, N; Bush, K; Yang, Y	1
Alonso, R; Cisterna, R; Colom, K; Fernández-Aranguiz, A; Morla, A; Suinaga, E; Umaran, A	1
Aldridge, KE; Morice, N; Schiro, DD	1
Chen, HY; Livermore, DM	1
Collins, L; Eliopoulos, GM; Malanoski, GJ; Moellering, RC; Wennersten, C	1
Jones, RN; Sader, HS	1
Hashizume, T; Hazumi, N; Kato, Y; Matsuda, K	1
Jin, YF; Piddock, LJ	1
Kumazawa, J; Matsumoto, T; Nagayama, A	1
Akerlund, JE; Andåker, L; Angerås, M; Bäckstrand, B; Bång, H; Brismar, B; Darle, N; Eklund, AE; Falk, A; Gasslander, T; Gustafsson, PO; Hagelbäck, A; Johansson, C; Kasholm-Tengve, B; Nord, CE; Nyström, PO; Olsson-Liljequist, B; Sjöstedt, S; Skau, T; Törnqvist, A; Tunevall, G	1
Kanazawa, K; Nouda, H; Sunagawa, M	1
Hirata, Y; Igari, J; Imafuku, Y; Inoue, M; Ishigo, S; Kawaguchi, R; Kobayashi, I; Kumasaka, K; Matsuoka, K; Murakami, E; Nishino, T; Oguri, T; Ohtaki, Y; Okada, J; Okamoto, E; Saeki, H; Satou, S; Shibano, T; Takahashi, A; Tokuda, K; Uchida, K; Uehara, N; Watanabe, N; Yomoda, S; Yoshida, H	1
Awaya, Y; Fujiue, Y; Kodomari, Y; Kuwabara, M; Muroki, K; Shimizu, S; Watanabe, Y	1
Horii, T; Ichiyama, S; Kobayashi, M; Ohta, M	1
Hirata, Y; Hongo, T; Igari, J; Imafuku, Y; Inoue, M; Kawaguchi, R; Kobayashi, I; Kobayasi, Y; Kumasaka, K; Matsumoto, N; Nakasaki, N; Nishino, T; Oguri, T; Ohtaki, Y; Okada, J; Saeki, H; Sasaki, T; Satou, S; Shibano, T; Takahashi, A; Tokuda, K; Uehara, N; Watanabe, N; Yomoda, S; Yoshida, H	1
Murase, M	1
Fujimura, S; Gomi, K; Honda, Y; Kikuchi, T; Kobayashi, T; Nukiwa, T; Shoji, S; Takahashi, H; Tokue, Y; Watanabe, A; Yasui, S	1
Aoki, N; Hashimoto, T; Hirata, Y; Hongo, T; Igari, J; Imafuku, Y; Inoue, M; Ishigo, S; Kajimura, K; Kawaguchi, R; Kobayashi, I; Kobayashi, Y; Kumasaka, K; Matsumoto, N; Matsuoka, K; Murakami, E; Nakasaki, N; Nishino, T; Oguri, T; Ohba, Y; Ohtaki, Y; Okada, J; Okamoto, E; Ono, J; Saeki, H; Sasaki, T; Satou, S; Shibano, T; Takahashi, A; Takata, T; Tokuda, K; Uehara, N; Watanabe, N; Yomoda, S; Yoshida, H	1
Endo, H; Jinbo, K; Nishinari, C; Suzuki, Y; Tamura, C	1
Hikida, M; Inoue, M; Okamoato, R; Sato, Y; Terashima, S	1
Araake, M; Gotoh, N; Hiraishi, T; Miyata, A; Nishino, T; Ogawa, H; Takata, T	1
Araake, M; Hara, T; Watabe, H	1
Inoue, M; Kaku, M; Nasu, M; Sagawa, K; Yokoyama, T	1
Aizawa, K; Sakakibara, S; Shimizu, A; Takata, T; Totsuka, K; Watabe, H	1
Hirota, K; Kayama, S; Miyake, Y; Mori, M; Murakami, K; Nemoto, K; Ono, T; Viducic, D	1
Doi, M; Fujiue, Y; Kuwabara, M; Muroki, K; Shimizu, S; Watanabe, Y; Yano, S	1
Hikida, M; Ito, F; Kataoka, H; Kijima, K; Maebashi, K; Mikami, Y; Muto, Y; Niida, M; Sakakibara, S; Shimizu, A; Suzuki, K; Takata, T; Takeda, K; Unno, M	1
Huang, A; Huang, W; Jia, B; Li, C; Lu, P; Wu, G; Zhang, G; Zhang, W; Zhou, X	1
Bonomo, RA; Endimiani, A; Papp-Wallace, KM; Taracila, MA	1
Citron, DM; Goldstein, EJ; Merriam, CV; Tyrrell, KL	1
Amicosante, G; Bottoni, C; Celenza, G; Colapietro, M; Compagnoni, C; Marcoccia, F; Maturo, MG; Perilli, M; Sabatini, A; Segatore, B	1
Barnes, SW; Dean, CR; Iartchouk, O; Jones, AK; Lee, PS; Mostafavi, M; Ranjitkar, S; Walker, JR; Willis, TW; Zwirko, Z	1
Bian, L; Zhang, Y	1
George Priya Doss, C; Gopikrishnan, M	1
Belz, DC; Deck, DH; Ignatius, EH; Lamichhane, G; Lippincott, CK; Nicklas, DA; Panthi, CM; Rimal, B; Serio, AW	1

Reviews

1 review(s) available for ljc 10627 and imipenem, anhydrous

Article	Year
Carbapenems: past, present, and future. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:11 Topics: Anti-Bacterial Agents; beta-Alanine; beta-Lactams; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Ertapenem; Humans; Imipenem; Thienamycins	2011

Trials

2 trial(s) available for ljc 10627 and imipenem, anhydrous

Article	Year
Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish Study Group. Scandinavian journal of infectious diseases, 1996, Volume: 28, Issue:5 Topics: Abdomen; Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Protease Inhibitors; Safety; Sweden; Thienamycins; Treatment Outcome	1996
A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections. Chemotherapy, 2010, Volume: 56, Issue:4 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hospitals, Teaching; Humans; Imipenem; Male; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections; Young Adult	2010

Article

Year

Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish Study Group.

Scandinavian journal of infectious diseases, 1996, Volume: 28, Issue:5

Topics: Abdomen; Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Protease Inhibitors; Safety; Sweden; Thienamycins; Treatment Outcome

1996

A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections.

Chemotherapy, 2010, Volume: 56, Issue:4

Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hospitals, Teaching; Humans; Imipenem; Male; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections; Young Adult

2010

Other Studies

49 other study(ies) available for ljc 10627 and imipenem, anhydrous

Article	Year
rpoN gene of Pseudomonas aeruginosa alters its susceptibility to quinolones and carbapenems. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Carbapenems; Gene Expression Regulation, Bacterial; Genes, Bacterial; Promoter Regions, Genetic; Pseudomonas aeruginosa; Quinolones; RNA Polymerase Sigma 54; Transcription, Genetic; Virulence	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship	2009
In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa	2010
Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. Journal of medicinal chemistry, 2015, May-14, Volume: 58, Issue:9 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Carbapenems; Crystallography, X-Ray; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Heterocyclic Compounds, 1-Ring; Mice; Microbial Sensitivity Tests; Models, Molecular; Rats; Stereoisomerism; Structure-Activity Relationship	2015
In-vitro activity of new carbapenem antibiotics: comparative studies with meropenem, L-627 and imipenem against pathogenic Nocardia spp. The Journal of antimicrobial chemotherapy, 1992, Volume: 29, Issue:2 Topics: Carbapenems; Imipenem; Meropenem; Microbial Sensitivity Tests; Nocardia; Thienamycins	1992
Renal dehydropeptidase-I stability of LJC 10,627, a new carbapenem antibiotic. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:2 Topics: Animals; Carbapenems; Chromatography, High Pressure Liquid; Dipeptidases; Humans; Hydrolysis; Imipenem; In Vitro Techniques; Kidney; Kinetics; Macaca fascicularis; Spectrophotometry, Ultraviolet; Swine; Thienamycins	1992
In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:1 Topics: Amikacin; Animals; Bacterial Infections; Bacteroides fragilis; Carbapenems; Ceftazidime; Cilastatin; Ciprofloxacin; Dipeptidases; Drug Therapy, Combination; Escherichia coli; Female; Imipenem; Klebsiella pneumoniae; Metronidazole; Mice; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Staphylococcus; Streptococcus; Thienamycins	1991
In vitro activity of LJC10,627, a new carbapenem antibiotic with high stability to dehydropeptidase I. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6 Topics: Animals; Bacterial Proteins; beta-Lactamases; Carbapenems; Carrier Proteins; Ceftazidime; Dipeptidases; Gram-Negative Bacteria; Gram-Positive Bacteria; Hexosyltransferases; Hydrolysis; Imipenem; Kidney; Kinetics; Microbial Sensitivity Tests; Microscopy, Phase-Contrast; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Swine; Thienamycins	1990
In vitro antibacterial activity and beta-lactamase stability of the new carbapenem LJC10,627. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8 Topics: Bacteria; beta-Lactamases; Carbapenems; Cefpirome; Ceftazidime; Cephalosporins; Humans; Imipenem; Molecular Structure; Thienamycins	1990
[In vitro activity of carbapenems (biapenem, imipenem and meropenem) and some other antibiotics against strict anaerobic bacteria]. Pathologie-biologie, 1995, Volume: 43, Issue:4 Topics: Bacteroides fragilis; Clostridium; Dose-Response Relationship, Drug; Eubacterium; Fusobacterium; Humans; Imipenem; In Vitro Techniques; Meropenem; Peptostreptococcus; Prevotella; Thienamycins	1995
Interactions of biapenem with active-site serine and metallo-beta-lactamases. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6 Topics: beta-Lactam Resistance; beta-Lactamases; Binding Sites; Enterobacteriaceae; Enzyme Activation; Enzyme Inhibitors; Imipenem; Kinetics; Metalloproteins; Microbial Sensitivity Tests; Serine; Thienamycins; Zinc	1995
Postantibiotic effect of carbapenems against Pseudomonas aeruginosa. The Journal of antibiotics, 1995, Volume: 48, Issue:8 Topics: Animals; Ceftazidime; Cephalosporins; Female; Imipenem; Meropenem; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	1995
The in-vitro activity of biapanem against 964 clinical isolates of aerobic bacteria. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:5 Topics: Bacteria, Aerobic; Humans; Imipenem; Microbial Sensitivity Tests; Thienamycins	1995
Biapenem versus imipenem in the treatment of experimental intraabdominal infections. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7, Issue:1 Topics: Abdomen; Animals; Bacteria; Bacterial Infections; Disease Models, Animal; Imipenem; Male; Microbial Sensitivity Tests; Rats; Rats, Sprague-Dawley; Thienamycins	1995
Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem. Toxicology letters, 1995, Volume: 76, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Cilastatin; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipenem; Injections, Intravenous; Male; Meropenem; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Thienamycins	1995
Postantibiotic effects of three carbapenems on Pseudomonas aeruginosa in the presence of lysine. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:1 Topics: Carbapenems; Imipenem; Lysine; Meropenem; Pseudomonas aeruginosa; Thienamycins	1995
Biochemical comparison of imipenem, meropenem and biapenem: permeability, binding to penicillin-binding proteins, and stability to hydrolysis by beta-lactamases. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:1 Topics: Bacteria; Bacterial Proteins; beta-Lactamases; Carrier Proteins; Cell Membrane Permeability; Hexosyltransferases; Hydrolysis; Imipenem; Kinetics; Meropenem; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Binding; Thienamycins	1995
In vitro activity of biapenem against beta-lactamase producing Enterobacteriaceae. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:10 Topics: beta-Lactamases; Cefotaxime; Enterobacteriaceae; Imipenem; Microbial Sensitivity Tests; Sensitivity and Specificity; Thienamycins	1994
In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4 Topics: Bacteria, Anaerobic; beta-Lactamases; Drug Resistance, Microbial; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins	1994
In-vitro activity of biapenem, compared with imipenem and meropenem, against Pseudomonas aeruginosa strains and mutants with known resistance mechanisms. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:5 Topics: beta-Lactamase Inhibitors; beta-Lactamases; Carbenicillin; Enzyme Induction; Hydrolysis; Imipenem; Meropenem; Microbial Sensitivity Tests; Mutation; Penicillin Resistance; Porins; Pseudomonas aeruginosa; Thienamycins	1994
In vitro activity of biapenem against clinical isolates of gram-positive and gram-negative bacteria. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9 Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Imipenem; Methicillin Resistance; Microbial Sensitivity Tests; Thienamycins	1993
Antimicrobial activity of the new carbapenem biapenem compared to imipenem, meropenem and other broad-spectrum beta-lactam drugs. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:5 Topics: Anti-Bacterial Agents; Bacteremia; Bacteria; Ceftazidime; Drug Resistance, Microbial; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins	1993
Effects of a beta-lactamase inhibitor, sulbactam, on the activity of carbapenems against Pseudomonas aeruginosa. The Journal of antibiotics, 1995, Volume: 48, Issue:11 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Drug Synergism; Enzyme Inhibitors; Imipenem; Meropenem; Pseudomonas aeruginosa; Sulbactam; Thienamycins	1995
Activity of biapenem (LJC 10627) against 51 imipenem-resistant bacteria and selection and characterisation of biapenem-resistant mutants. The Journal of antimicrobial chemotherapy, 1995, Volume: 36, Issue:5 Topics: Drug Resistance, Microbial; Gram-Negative Bacteria; Imipenem; Thienamycins	1995
Sensitivities to four carbapenems of bacteria isolated from patients with refractory complicated urinary tract infections and the detection of carbapenemase-producing Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins; Urinary Tract Infections	1996
Structure-activity relationships of carbapenem compounds to anti-Haemophilus influenzae activity and affinity for penicillin-binding proteins. Effect of 1 beta-methyl group and C-2 side chain. The Journal of antibiotics, 1997, Volume: 50, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Carbapenems; Carrier Proteins; Haemophilus influenzae; Hexosyltransferases; Imipenem; Meropenem; Methylation; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Binding; Structure-Activity Relationship; Thienamycins	1997
[Survey of sensitivities of clinical isolates to antibacterial agents (annual report)]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:8 Topics: 4-Quinolones; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Carbapenems; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Cocci; Haemophilus influenzae; Humans; Imipenem; Meropenem; Monobactams; Penicillins; Pseudomonas aeruginosa; Serratia marcescens; Thienamycins	1997
[The antimicrobial susceptibilities and serotypes of Pseudomonas aeruginosa isolated from sputum]. The Japanese journal of antibiotics, 1998, Volume: 51, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Carbapenems; Cefozopran; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Humans; Imipenem; Meropenem; Monobactams; Penicillins; Piperacillin; Pseudomonas aeruginosa; Serotyping; Sputum; Thienamycins	1998
Relationship between morphological changes and endotoxin release induced by carbapenems in Pseudomonas aeruginosa. Journal of medical microbiology, 1999, Volume: 48, Issue:3 Topics: Carbapenems; Endotoxins; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	1999
[Survey of the sensitivities of clinical isolates to antibacterial agents (annual report)]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:4 Topics: Carbapenems; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins; Time Factors	1999
[In vitro antibacterial activities of carbapenems against clinical isolates]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:11 Topics: Bacteria; Enterobacteriaceae; Imipenem; Meropenem; Methicillin Resistance; Pseudomonas aeruginosa; Staphylococcus aureus; Thienamycins	1999
[In vitro activity of biapenem (BIPM) against clinically isolated respiratory pathogens in 1996-1998]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:12 Topics: Bacteria; Carbapenems; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Humans; Imipenem; Meropenem; Penicillins; Piperacillin; Respiratory Tract Infections; Thienamycins; Time Factors	1999
[Changes in the antibacterial activity of chemotherapeutic agents (especially carbapenems) for 10 species of clinical isolates between 1994 and 1996. Surveillance group of the sensitivities of clinical isolates to antibacterial agents]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:3 Topics: Bacteria; Carbapenems; Drug Resistance, Microbial; Humans; Imipenem; Japan; Meropenem; Multicenter Studies as Topic; Thienamycins; Time Factors	2000
[Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains]. The Japanese journal of antibiotics, 2001, Volume: 54, Issue:9 Topics: Bacteria; Carbapenems; Cefepime; Cefozopran; Cephalosporins; Imipenem; Meropenem; Thienamycins	2001
[Comparative antibacterial activity of carbapenems against P. aeruginosa (1)]. The Japanese journal of antibiotics, 2001, Volume: 54, Issue:11 Topics: beta-Lactamases; Carbapenems; Drug Resistance, Microbial; Imipenem; Meropenem; Pseudomonas aeruginosa; Thienamycins	2001
[Bactericidal activity of biapenem against various efflux system mutants of Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:1 Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Imipenem; Meropenem; Mutation; Pseudomonas aeruginosa; Thienamycins	2002
[Antibacterial activity of biapenem against recent clinical isolates]. The Japanese journal of antibiotics, 2003, Volume: 56, Issue:2 Topics: Bacteria; Bacterial Infections; beta-Alanine; Carbapenems; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Thienamycins	2003
[Proper use of carbapenem antibiotics based on the feature in the treatment of infectious diseases (discussion)]]. The Japanese journal of antibiotics, 2004, Volume: 57, Issue:1 Topics: Bacteria; Bacterial Infections; beta-Alanine; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Administration Schedule; Drug Combinations; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Thienamycins; Treatment Failure	2004
Optimization of dose and dose regimen of biapenem based on pharmacokinetic and pharmacodynamic analysis. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2004, Volume: 10, Issue:2 Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Drug Administration Schedule; Humans; Imipenem; Male; Meropenem; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Thigh	2004
Role for rpoS gene of Pseudomonas aeruginosa in antibiotic tolerance. FEMS microbiology letters, 2005, Jan-01, Volume: 242, Issue:1 Topics: Adaptation, Physiological; Anti-Infective Agents; Bacterial Proteins; Colony Count, Microbial; Drug Tolerance; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hot Temperature; Imipenem; Mutation; Osmotic Pressure; Pseudomonas aeruginosa; Sigma Factor; Signal Transduction; Thienamycins	2005
[Antimicrobial susceptibility of Pseudomonas aeruginosa isolated from urine at one hospital to mainly carbapenem and fluoroquinolone drugs]. The Japanese journal of antibiotics, 2006, Volume: 59, Issue:2 Topics: Amikacin; Anti-Infective Agents; Carbapenems; Ceftazidime; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Meropenem; Oxazines; Piperacillin; Pseudomonas aeruginosa; Thienamycins; Urine	2006
Pharmacokinetic and pharmacodynamic properties of biapenem, a carbapenem antibiotic, in rat experimental model of severe acute pancreatitis. Pancreas, 2008, Volume: 36, Issue:2 Topics: Acute Disease; Animals; Anti-Bacterial Agents; Ascites; Bacterial Infections; Disease Models, Animal; Dose-Response Relationship, Drug; Imipenem; Injections, Subcutaneous; Intestines; Lymph Nodes; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar; Severity of Illness Index; Taurocholic Acid; Thienamycins	2008
In vitro activity of Biapenem plus RPX7009, a carbapenem combined with a serine β-lactamase inhibitor, against anaerobic bacteria. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; beta-Lactamase Inhibitors; Carbapenems; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Gram-Positive Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Prevotella; Serine; Thienamycins	2013
Identification of New Natural CphA Metallo-β-Lactamases CphA4 and CphA5 in Aeromonas veronii and Aeromonas hydrophila Isolates from Municipal Sewage in Central Italy. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Aeromonas hydrophila; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Ertapenem; Imipenem; Italy; Molecular Sequence Data; Point Mutation; Sewage; Thienamycins	2015
Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:2 Topics: beta-Lactams; Imipenem; Microbial Sensitivity Tests; Monobactams; Piperidines; Pseudomonas aeruginosa; Quaternary Ammonium Compounds; Tazobactam; Thienamycins; Transcriptome	2019
Recognition and interaction of CphA from Aeromonas hydrophila with imipenem and biapenem by spectroscopic analysis in combination with molecular docking. Journal of molecular recognition : JMR, 2019, Volume: 32, Issue:8 Topics: Aeromonas hydrophila; Bacterial Proteins; beta-Lactamases; Binding Sites; Hydrogen Bonding; Hydrolysis; Imipenem; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Thienamycins	2019
Molecular docking and dynamic approach to screen the drug candidate against the Imipenem-resistant CarO porin in Acinetobacter baumannii. Microbial pathogenesis, 2023, Volume: 177 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Carbapenems; Doripenem; Ertapenem; Imipenem; Meropenem; Microbial Sensitivity Tests; Molecular Docking Simulation; Porins	2023
Efficacy of Omadacycline-Containing Regimen in a Mouse Model of Pulmonary Mycobacteroides abscessus Disease. mSphere, 2023, 04-20, Volume: 8, Issue:2 Topics: Animals; Anti-Bacterial Agents; Cefoxitin; Cystic Fibrosis; Imipenem; Linezolid; Mice; Microbial Sensitivity Tests; Mycobacterium abscessus; Rifabutin; Tetracyclines	2023