Page last updated: 2024-08-25

ljc 10627 and cilastatin

ljc 10627 has been researched along with cilastatin in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (33.33)	18.2507
2000's	4 (44.44)	29.6817
2010's	2 (22.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Jacobus, NV; Petersen, PJ; Testa, RT; Weiss, WJ	1
Day, IP; Goudie, J; Nishiki, K; Williams, PD	1
Akerlund, JE; Andåker, L; Angerås, M; Bäckstrand, B; Bång, H; Brismar, B; Darle, N; Eklund, AE; Falk, A; Gasslander, T; Gustafsson, PO; Hagelbäck, A; Johansson, C; Kasholm-Tengve, B; Nord, CE; Nyström, PO; Olsson-Liljequist, B; Sjöstedt, S; Skau, T; Törnqvist, A; Tunevall, G	1
Araake, M; Hara, T; Watabe, H	1
Inoue, M; Kaku, M; Nasu, M; Sagawa, K; Yokoyama, T	1
Huang, A; Huang, W; Jia, B; Li, C; Lu, P; Wu, G; Zhang, G; Zhang, W; Zhou, X	1
Bonomo, RA; Endimiani, A; Papp-Wallace, KM; Taracila, MA	1

Reviews

1 review(s) available for ljc 10627 and cilastatin

Article	Year
Carbapenems: past, present, and future. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:11 Topics: Anti-Bacterial Agents; beta-Alanine; beta-Lactams; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Ertapenem; Humans; Imipenem; Thienamycins	2011

Trials

2 trial(s) available for ljc 10627 and cilastatin

Article	Year
Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish Study Group. Scandinavian journal of infectious diseases, 1996, Volume: 28, Issue:5 Topics: Abdomen; Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Protease Inhibitors; Safety; Sweden; Thienamycins; Treatment Outcome	1996
A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections. Chemotherapy, 2010, Volume: 56, Issue:4 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hospitals, Teaching; Humans; Imipenem; Male; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections; Young Adult	2010

Article

Year

Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish Study Group.

Scandinavian journal of infectious diseases, 1996, Volume: 28, Issue:5

Topics: Abdomen; Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacterial Infections; Cilastatin; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Protease Inhibitors; Safety; Sweden; Thienamycins; Treatment Outcome

1996

A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections.

Chemotherapy, 2010, Volume: 56, Issue:4

Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Hospitals, Teaching; Humans; Imipenem; Male; Middle Aged; Respiratory Tract Infections; Thienamycins; Urinary Tract Infections; Young Adult

2010

Other Studies

6 other study(ies) available for ljc 10627 and cilastatin

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:1 Topics: Amikacin; Animals; Bacterial Infections; Bacteroides fragilis; Carbapenems; Ceftazidime; Cilastatin; Ciprofloxacin; Dipeptidases; Drug Therapy, Combination; Escherichia coli; Female; Imipenem; Klebsiella pneumoniae; Metronidazole; Mice; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Staphylococcus; Streptococcus; Thienamycins	1991
Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem. Toxicology letters, 1995, Volume: 76, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Cilastatin; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipenem; Injections, Intravenous; Male; Meropenem; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Thienamycins	1995
[Antibacterial activity of biapenem against recent clinical isolates]. The Japanese journal of antibiotics, 2003, Volume: 56, Issue:2 Topics: Bacteria; Bacterial Infections; beta-Alanine; Carbapenems; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Thienamycins	2003
[Proper use of carbapenem antibiotics based on the feature in the treatment of infectious diseases (discussion)]]. The Japanese journal of antibiotics, 2004, Volume: 57, Issue:1 Topics: Bacteria; Bacterial Infections; beta-Alanine; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Administration Schedule; Drug Combinations; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Thienamycins; Treatment Failure	2004