Page last updated: 2024-09-03

lithocholate 3-o-glucuronide and lithocholic acid

lithocholate 3-o-glucuronide has been researched along with lithocholic acid in 12 studies

Compound Research Comparison

Studies
(lithocholate 3-o-glucuronide)
Trials
(lithocholate 3-o-glucuronide)
Recent Studies (post-2010)
(lithocholate 3-o-glucuronide)
Studies
(lithocholic acid)
Trials
(lithocholic acid)
Recent Studies (post-2010) (lithocholic acid)
13011,11124280

Protein Interaction Comparison

ProteinTaxonomylithocholate 3-o-glucuronide (IC50)lithocholic acid (IC50)
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1Homo sapiens (human)4.823
60 kDa heat shock protein, mitochondrialHomo sapiens (human)10
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)6.12
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)2.71
10 kDa heat shock protein, mitochondrialHomo sapiens (human)10
Bile acid receptorHomo sapiens (human)0.0183
large T antigenBetapolyomavirus macacae26.1

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's7 (58.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lehman, P; Lester, R; Little, JM; Radominska, A; Zimniak, P1
Kasama, T; Ohki, H; Sano, N; Takikawa, H; Yamanaka, M1
Takemura, T; Takikawa, H; Tomita, J; Yamanaka, M1
Lester, R; Little, JM; Radominska, A; Shattuck, KE; Zimniak, P1
Ohki, H; Sano, N; Takikawa, H; Yamanaka, M1
Adcock, EW; Lester, R; Little, JM; Oelberg, DG1
Adcock, EW; Chari, MV; Lester, R; Little, JM; Oelberg, DG1
Sano, N; Takikawa, H; Yamanaka, M; Yamazaki, R1
Minagawa, K; Sano, N; Takikawa, H; Yamanaka, M1
Sano, N; Takikawa, H; Wako, Y; Yamanaka, M1
Chen, G; Czernik, P; Gall, WE; Little, JM; Magdalou, J; Radominska-Pandya, A; Samokyszyn, VM; Terrier, N; Zawada, G1
Arnold, LA; Bikle, DD; Bogart, JW; Cook, JM; Preston, JV; Sanchez, LM; Silvaggi, NR; Teske, KA; Yu, OB1

Other Studies

12 other study(ies) available for lithocholate 3-o-glucuronide and lithocholic acid

ArticleYear
Urinary excretion of lithocholic acid and its conjugates by the bile duct-ligated rat.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:4 Pt 1

    Topics: Animals; Bile Ducts; Chromatography, Thin Layer; Glucuronates; Ligation; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Taurolithocholic Acid

1991
Cholestasis induced by lithocholate and its glucuronide: their biliary excretion and metabolism.
    Biochimica et biophysica acta, 1991, Jan-04, Volume: 1081, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Bilirubin; Cholestasis; Chromatography, Thin Layer; Glucuronates; Kinetics; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Spectrometry, Mass, Fast Atom Bombardment

1991
Cytotoxic effect and uptake mechanism by isolated rat hepatocytes of lithocholate and its glucuronide and sulfate.
    Biochimica et biophysica acta, 1991, Jan-31, Volume: 1091, Issue:2

    Topics: Animals; Bile Acids and Salts; Biotransformation; Cell Survival; Cells, Cultured; Diffusion; Glucuronates; Lithocholic Acid; Liver; Male; Rats; Rats, Inbred Strains; Sulfates; Sulfobromophthalein

1991
Metabolism of lithocholic acid in the rat: formation of lithocholic acid 3-O-glucuronide in vivo.
    Journal of lipid research, 1990, Volume: 31, Issue:4

    Topics: Animals; Bile; Chromatography, High Pressure Liquid; Glucuronates; Kinetics; Lithocholic Acid; Liver; Male; Rats; Rats, Inbred Strains

1990
Comparison of biliary excretion and metabolism of lithocholic acid and its sulfate and glucuronide conjugates in rats.
    Biochimica et biophysica acta, 1989, Aug-08, Volume: 1004, Issue:2

    Topics: Animals; Bile; Biotransformation; Chromatography, Thin Layer; Glucuronates; Hydroxylation; Kinetics; Lithocholic Acid; Liver; Male; Rats; Rats, Inbred Strains

1989
Intestinal absorption of bile acid glucuronides in rats.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:9

    Topics: Animals; Bile Acids and Salts; Cholic Acids; Glucuronates; Ileum; Intestinal Absorption; Jejunum; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Taurocholic Acid

1988
Lithocholate glucuronide is a cholestatic agent.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:6

    Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Cholestasis; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucuronates; Kinetics; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Tritium

1984
Colchicine inhibits lithocholate-3-O-glucuronide-induced cholestasis in rats.
    Journal of hepatology, 1995, Volume: 22, Issue:1

    Topics: Animals; Bile; Cholestasis; Colchicine; Glucuronates; Lithocholic Acid; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Vinblastine

1995
Lithocholate-3-O-glucuronide-induced cholestasis. A study with congenital hyperbilirubinemic rats and effects of ursodeoxycholate conjugates.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:8

    Topics: Animals; Bile; Cholestasis; Glucuronates; Hyperbilirubinemia, Hereditary; Lithocholic Acid; Liver; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1993
Changes in biliary excretory mechanisms in bile duct-ligated rat.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts; Glucuronates; Glutathione; Ligation; Lithocholic Acid; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid

1996
Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II.
    Protein science : a publication of the Protein Society, 2001, Volume: 10, Issue:1

    Topics: Alitretinoin; Animals; Glucuronates; Glucuronosyltransferase; Humans; Lithocholic Acid; Microsomes, Liver; Photoaffinity Labels; Rats; Receptors, Retinoic Acid; Recombinant Proteins; Structure-Activity Relationship; Tretinoin; Tritium

2001
Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites.
    European journal of medicinal chemistry, 2016, Feb-15, Volume: 109

    Topics: Calcitriol; Cell Line, Tumor; Cholesterol; Glucuronates; Humans; Lithocholic Acid; Male; Prostatic Neoplasms; Receptors, Calcitriol; Transcription, Genetic; Vitamin D; Vitamin D3 24-Hydroxylase

2016