lithium-chloride and sodium-bromide

Water authorities interested in the evaluation of the structural state of a sewer must quantify leakage to plan strategic intervention. However, the quantification of the exfiltration and the localisation of structural damage are challenging tasks that usually require expensive and time-consuming inspections. Herein, we report one of the first applications of the QUEST-C method to quantify the exfiltration in a continuously operating sewer by dosing two chemical tracers, sodium bromide (NaBr) and lithium chloride (LiCl). The method was applied at the catchment scale in a 14-year-old sewer in Rome, Italy. Preliminary laboratory tests, field measurements, and numerical simulations showed that reliable results require the QUEST-C method to be applied to sewers without lateral inflows, during periods of quasi-steady flow, and that the travel time of the NaBr tracer is minimised. Three sewer reaches were tested and the estimated exfiltration, as a fraction of the dry weather flow (DWF), increased from 0.128 in the agricultural area to 0.208 in the urban area. Although our estimates are at the lower end of the range given in the literature (0.01-0.56 DWF), the exfiltration was not negligible, and interventions should focus on the sewers in urban areas. This illustrates the capability of the QUEST-C method to guide strategic intervention at low cost and without an interruption of sewer operation. However, careful interpretation of the results is recommended for sewers with many lateral inflows, where leakage may be overestimated.

Topics: Bromides; Drainage, Sanitary; Environmental Monitoring; Lithium Chloride; Reproducibility of Results; Rome; Sewage; Sodium Compounds; Waste Disposal, Fluid

Antidepressant drug imipramine hydrochloride (IMP) is amphiphilic which shows surfactant-like behavior in aqueous solutions. We have studied the effect of adding electrolytes and non-electrolytes on the micellar behavior of IMP by making cloud point (CP) and dye solubilization measurements. The CP of a 100mM IMP solution (prepared in 10mM sodium phosphate (SP) buffer) was found to decrease with increasing pH, both in the absence as well as presence of added salts. Increase in pH increased the visible absorbance of Sudan III dye solubilized in the drug micelles, implying micellar growth. Addition of increasing amounts of salts to 100mM IMP solutions (at pH 6.7) caused continuous increase in CP due to micellar growth. On the basis of these studies, the binding-effect orders of counter- and co-ions have been deduced, respectively, as: Br(-)>Cl(-)>F(-) and Li(+)

Topics: Azo Compounds; Bromides; Coloring Agents; Electrolytes; Emulsions; Hydrogen-Ion Concentration; Imipramine; Lithium Chloride; Lithium Compounds; Micelles; Potassium Chloride; Potassium Compounds; Quaternary Ammonium Compounds; Sodium Chloride; Sodium Compounds; Sodium Fluoride; Solubility; Solutions; Thiourea; Urea

In the temperature-composition phase diagram of the nonionic surfactant n-octyl-hydroxypenta(oxyethylene), C(8)E(5), there are three principal curves; the one for the critical micelle concentration (cmc), the one delineating the existence of the hexagonal phase, and then the lower consolute boundary (lcb). In this work it is clarified how the presence of the alkali halides NaF, LiCl, NaCl, NaBr and NaI in the aqueous solutions, up to high molalities, change the lcb temperature-position and shape. The lcbs are obtained from measurements of cloud-point temperatures. Rather marked anion-controlled shifts are observed in the boundary temperature-position, and the order of the anions is in accordance with the prediction of the Hofmeister series. Also the shape of the boundary is affected in an anion-specific way, so that the largest changes are found with the strongest salting-out agent. The separation point varies in distinctly non-linear manners with the molality of the studied alkali halides. An approach is presented that can reproduce the effects of the alkali halides on the cloud-point temperature of C(8)E(5) and a poly(ethylene oxide) polymer, at low amounts of the macroentities. In this approach use is made of the known behaviour of the electrolytes at the air/water surface and the virial expansion, to account for the initial salting-out/-in effect and the variation of the effect with electrolyte molality.

Topics: Bromides; Ethers; Lithium Chloride; Micelles; Polyethylene Glycols; Sodium Chloride; Sodium Compounds; Sodium Fluoride; Sodium Iodide; Surface Properties; Surface-Active Agents; Thermodynamics

Composite effects of pH and halide ions on the transport of HgCl2 into brush border membrane vesicles (BBMV) were investigated in rats. BBMV were incubated for 10 min. in buffer solution at different pH containing 10(-4) M HgCl2. The increase in pH increased the uptake of Hg by BBMV as a result of the increase in transport of Hg into intravesicular space and decrease in binding of Hg to BBMV. The isotonic displacement of NaCl in the buffer solution by LiCl or KCl did not change the uptake of Hg at each pH. The displacement of NaCl by mannitol increased the uptake of Hg at each pH, while the displacement by NaBr or NaI decreased the uptake and diminished the increasing effect of pH on the uptake of Hg. These changes in uptake of Hg due to the displacement were mainly ascribed to the changes in transport of Hg. These results suggest that the increase in pH mainly increases the transport of HgCl2 as a result of the conversion to hydroxide forms of Hg such as Hg(OH)Cl and Hg(OH)2, and Cl- Br- and I- act as the competing ions with OH- and decrease the transport of Hg.

Topics: Animals; Biological Transport; Bromides; Chlorides; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Lithium; Lithium Chloride; Mercuric Chloride; Microvilli; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Sodium Compounds

The denaturation of ribonuclease A by guanidine hydrochloride, lithium bromide, and lithium chloride and by mixed denaturants consisting of guanidine hydrochloride and one of the denaturants lithium chloride, lithium bromide, and sodium bromide was followed by difference spectral measurements at pH 4.8 and 25 degrees C. Both components of mixed denaturant systems enhance each other's effect in unfolding the protein. The effect of lithium bromide on the midpoint of guanidine hydrochloride denaturation transition is approximately the sum of the effects of the constituent ions. For all the mixed denaturants tested, the dependence of the free energy change on denaturation is linear. The conformational free energy associated with the guanidine hydrochloride denaturation transition in water is 7.5 +/- 0.1 kcal mol-1, and it is unchanged in the presence of low concentrations of lithium bromide, lithium chloride, and sodium bromide which by themselves are not concentrated enough to unfold the protein. The conformational free energy associated with the lithium bromide denaturation transition in water is 11.7 +/- 0.3 kcal mol-1, and it is not affected by the presence of low concentrations of guanidine hydrochloride which by themselves do not disrupt the structure of native ribonuclease A.

Topics: Animals; Bromides; Calorimetry; Cattle; Chlorides; Guanidine; Guanidines; Kinetics; Lithium; Lithium Chloride; Lithium Compounds; Pancreas; Protein Denaturation; Ribonuclease, Pancreatic; Sodium; Sodium Compounds; Thermodynamics