lithium-chloride and imidazole

lithium-chloride has been researched along with imidazole* in 2 studies

Other Studies

2 other study(ies) available for lithium-chloride and imidazole

Article	Year
Kinetics and mechanism of imidazole-catalyzed acylation of cellulose in LiCl/N,N-dimethylacetamide. Carbohydrate polymers, 2013, Feb-15, Volume: 92, Issue:2 Cellulose acylation by anhydrides (ethanoic to hexanoic) plus tosyl chloride, TsCl, or imidazole in LiCl/N,N-dimethylacetamide solution has been studied. Contrary to a previous claim, TsCl does not catalyze acylation. For the diazole-catalyzed reaction, N-acylimidazole is the acylating agent. Third order rate constants (k(3); 40-70 °C) have been calculated from conductivity data and split, by using information from model compounds, into contributions from the primary- (k(3;Prim(OH))) and secondary- (k(3;Sec(OH))) hydroxyl groups of cellulose. Values of k(3,Prim(OH))/k(3,Sec(OH)) are >1, and increase linearly as a function of increasing the number of carbon atoms of the acyl group. Rate constants and the degree of biopolymer substitution decrease on going from ethanoic- to butanoic-, then increase for pentanoic- and hexanoic anhydride, due to enthalpy/entropy compensation. Relative to the uncatalyzed reaction, the diazole-mediated one is associated with smaller enthalpy- and larger entropy of activation, due to difference of the acylating agent. Topics: Acetamides; Acylation; Anhydrides; Catalysis; Cellulose; Entropy; Imidazoles; Kinetics; Lithium Chloride; Tosyl Compounds	2013
The Morita-Baylis-Hillman adducts of beta-aryl nitroethylenes with other activated alkenes: synthesis and anticancer activity studies. Chemical communications (Cambridge, England), 2006, Jan-21, Issue:3 The Morita-Baylis-Hillman (MBH) adducts of beta-aryl nitroethylenes with methyl vinyl ketone (MVK) and acrylate, formed in moderate to good yield when mediated by imidazole/LiCl in THF at room temperature, inhibit HeLa cell proliferation by binding to tubulin. Topics: Acrylates; Alkenes; Antineoplastic Agents; Binding Sites; Butanones; Cell Proliferation; Ethylenes; Furans; HeLa Cells; Humans; Imidazoles; Lithium Chloride; Models, Chemical; Nitro Compounds; Temperature; Tubulin	2006

Article

Year

Kinetics and mechanism of imidazole-catalyzed acylation of cellulose in LiCl/N,N-dimethylacetamide.

Carbohydrate polymers, 2013, Feb-15, Volume: 92, Issue:2

Cellulose acylation by anhydrides (ethanoic to hexanoic) plus tosyl chloride, TsCl, or imidazole in LiCl/N,N-dimethylacetamide solution has been studied. Contrary to a previous claim, TsCl does not catalyze acylation. For the diazole-catalyzed reaction, N-acylimidazole is the acylating agent. Third order rate constants (k(3); 40-70 °C) have been calculated from conductivity data and split, by using information from model compounds, into contributions from the primary- (k(3;Prim(OH))) and secondary- (k(3;Sec(OH))) hydroxyl groups of cellulose. Values of k(3,Prim(OH))/k(3,Sec(OH)) are >1, and increase linearly as a function of increasing the number of carbon atoms of the acyl group. Rate constants and the degree of biopolymer substitution decrease on going from ethanoic- to butanoic-, then increase for pentanoic- and hexanoic anhydride, due to enthalpy/entropy compensation. Relative to the uncatalyzed reaction, the diazole-mediated one is associated with smaller enthalpy- and larger entropy of activation, due to difference of the acylating agent.

Topics: Acetamides; Acylation; Anhydrides; Catalysis; Cellulose; Entropy; Imidazoles; Kinetics; Lithium Chloride; Tosyl Compounds

2013

The Morita-Baylis-Hillman adducts of beta-aryl nitroethylenes with other activated alkenes: synthesis and anticancer activity studies.

Chemical communications (Cambridge, England), 2006, Jan-21, Issue:3

The Morita-Baylis-Hillman (MBH) adducts of beta-aryl nitroethylenes with methyl vinyl ketone (MVK) and acrylate, formed in moderate to good yield when mediated by imidazole/LiCl in THF at room temperature, inhibit HeLa cell proliferation by binding to tubulin.

Topics: Acrylates; Alkenes; Antineoplastic Agents; Binding Sites; Butanones; Cell Proliferation; Ethylenes; Furans; HeLa Cells; Humans; Imidazoles; Lithium Chloride; Models, Chemical; Nitro Compounds; Temperature; Tubulin

2006