lithium-chloride has been researched along with carbene* in 2 studies
2 other study(ies) available for lithium-chloride and carbene
| Article | Year |
|---|---|
An Enantioselective Assembly of Dihydropyranones through an NHC/LiCl-Mediated in situ Activation of α,β-Unsaturated Carboxylic Acids.
A straightforward N-heterocyclic carbene (NHC)/LiCl-mediated synthesis of dihydropyranones from α,β-unsaturated carboxylic acids and 1,3-dicarbonyl compounds was realized through the in situ activation strategy. The key advantages of this protocol include ready availability and high stability of starting materials, good yields, and excellent enantioselectivity. Topics: Carboxylic Acids; Catalysis; Heterocyclic Compounds; Lithium Chloride; Methane; Pyrones; Stereoisomerism | 2016 |
Asymmetric synthesis of highly substituted β-lactones through oxidative carbene catalysis with LiCl as cooperative Lewis acid.
The reaction of enals with β-diketones, β-ketoesters, and malonates bearing a β-oxyalkyl substituent at the α-position by oxidative NHC catalysis to provide highly substituted β-lactones is described. Reactions occur with excellent diastereo- and enantioselectivity. The organo cascade comprises two CC bond formations and one CO bond formation. Up to four contiguous stereogenic centers including two fully substituted stereocenters are formed in the cascade. Topics: Catalysis; Cyclohexanes; Lactones; Lewis Acids; Lithium Chloride; Methane; Oxidants; Oxidation-Reduction; Stereoisomerism | 2014 |