lithium-chloride has been researched along with aniline* in 1 studies
1 other study(ies) available for lithium-chloride and aniline
Article | Year |
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Palladium on carbon-catalyzed synthesis of 2- and 2,3-substituted indoles under heterogeneous conditions.
A mild, efficient and LiCl-free synthetic method for indole derivatives based on the heteroannulation of alkynes with 2-iodoanilines was achieved using palladium on carbon (Pd/C) and NaOAc in heated NMP. The N-tosyl protection of 2-iodoaniline expedited the reaction progress, while other protecting groups, such as tert-butoxycarbonyl, acetyl, and benzyloxycarbonyl groups, underwent deprotection under the present conditions. A variety of di- and monosubstituted alkynes could effectively react with N-tosyl-2-iodoaniline to give the corresponding indoles in good to high yields. Topics: Alkynes; Aniline Compounds; Carbon; Catalysis; Indoles; Lithium Chloride; Palladium | 2010 |