Page last updated: 2024-08-23

lithium and ketamine

lithium has been researched along with ketamine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's1 (4.76)18.2507
2000's3 (14.29)29.6817
2010's7 (33.33)24.3611
2020's7 (33.33)2.80

Authors

AuthorsStudies
Männistö, PT; Saarnivaara, L1
Inoue, O; Itoh, T; Suhara, T; Tsukada, H; Yamasaki, T; Yonezawa, H1
Biron, P; Latour, R1
Rubin, EH; Wooten, GF1
Cook, LL1
Persinger, MA; St-Pierre, LS1
Brody, SA; Geyer, MA; Large, CH; Ong, JC1
Budni, J; Dal-Pizzol, F; Deroza, PF; Fraga, Dde B; Ghedim, FV; Oliveira, MB; Quevedo, J; Steckert, AV; Valvassori, SS; Zugno, AI1
Barbas, C; Laje, G; Lorenzo, MP; Ramamoorthy, A; Silva dos Santos, M; Villaseñor, A; Wainer, IW; Zarate, C1
Löscher, W1
Ballard, ED; Brutsche, NE; Ionescu, DF; Luckenbaugh, DA; Lundin, NB; Machado-Vieira, R; Niciu, MJ; Richards, EM; Vande Voort, JL; Xu, AJ; Zarate, CA1
Costemale-Lacoste, JF; Gaillard, R; Guilloux, JP1
Campos, BC; da Costa, RO; de Aquino, PE; de Barros Viana, GS; de Vasconcelos, SM; do Vale, EM; Leal, LK; Neves, KR; Nogueira, BG; Xavier, CC1
Luckenbaugh, DA; Niciu, MJ; Pennybaker, SJ; Zarate, CA1
Ayala, K; Collins, L; Ettenberg, A; Fisher, MPA; Krug, JT; Mayes, MS1
Bakker, IM; Kamphuis, J; Schoevers, RA; Smith-Apeldoorn, SY; Touw, DJ; Veraart, JKE; Visser, BAE1
Butters, K; Frye, MA; McGee, SL; Morath, BA; Price, JB; Tye, SJ; Van De Wakker, SK; Yates, CG; Yates, NJ1
Buoli, M; Caldiroli, A; Capellazzi, M; Capuzzi, E; Clerici, M; Colmegna, F; Dakanalis, A; Marcatili, M; Mucci, F; Tagliabue, I1
Honyashiki, M; Inoue, T; Terao, I1
Gao, TH; Li, T; Ma, XH; Ni, PY; Ni, RJ; Tian, Y; Wang, YY; Wei, JX; Zhao, LS1
Endo, K; Kodama, W; Terao, I; Tsuge, T1

Reviews

6 review(s) available for lithium and ketamine

ArticleYear
Single versus combinatorial therapies in status epilepticus: Novel data from preclinical models.
    Epilepsy & behavior : E&B, 2015, Volume: 49

    Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Ketamine; Lithium; Phenobarbital; Pilocarpine; Rats; Seizures; Status Epilepticus

2015
The role of GSK-3 in treatment-resistant depression and links with the pharmacological effects of lithium and ketamine: A review of the literature.
    L'Encephale, 2016, Volume: 42, Issue:2

    Topics: Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Ketamine; Lithium; Mood Disorders

2016
Symptomatology and predictors of antidepressant efficacy in extended responders to a single ketamine infusion.
    Journal of affective disorders, 2017, Jan-15, Volume: 208

    Topics: Adult; Alcohol-Related Disorders; Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Female; Humans; Infusions, Intravenous; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid

2017
Pharmacodynamic Interactions Between Ketamine and Psychiatric Medications Used in the Treatment of Depression: A Systematic Review.
    The international journal of neuropsychopharmacology, 2021, 10-23, Volume: 24, Issue:10

    Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depression; Drug Interactions; Female; Haloperidol; Humans; Ketamine; Lithium; Male; Olanzapine; Psychotropic Drugs; Risperidone; Schizophrenia; Treatment Outcome

2021
Augmentative Pharmacological Strategies in Treatment-Resistant Major Depression: A Comprehensive Review.
    International journal of molecular sciences, 2021, Dec-02, Volume: 22, Issue:23

    Topics: Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Second-Generation; Buspirone; Central Nervous System Stimulants; Depressive Disorder, Treatment-Resistant; Humans; Ketamine; Lithium

2021
Comparative efficacy, tolerability and acceptability of intravenous racemic ketamine with intranasal esketamine, aripiprazole and lithium as augmentative treatments for treatment-resistant unipolar depression: A systematic review and network meta-analysis
    Journal of affective disorders, 2024, Feb-01, Volume: 346

    Topics: Adult; Antidepressive Agents; Aripiprazole; Depression; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Humans; Ketamine; Lithium; Network Meta-Analysis

2024

Trials

2 trial(s) available for lithium and ketamine

ArticleYear
A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial networks.
    British journal of pharmacology, 2014, Volume: 171, Issue:8

    Topics: Adult; Antidepressive Agents; Biomarkers, Pharmacological; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolome; Middle Aged; Pilot Projects; Valproic Acid; Young Adult

2014
Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression.
    Neural plasticity, 2015, Volume: 2015

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid

2015

Other Studies

13 other study(ies) available for lithium and ketamine

ArticleYear
Effect of lithium and rubidium on the sleeping time caused by various intravenous anaesthetics in the mouse.
    British journal of anaesthesia, 1976, Volume: 48, Issue:3

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Animals; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ketamine; Lithium; Male; Methohexital; Mice; Propanidid; Rubidium; Sleep; Thiopental; Time Factors

1976
Effect of lithium and anesthetics on in vivo binding of dopamine receptors.
    Acta radiologica. Supplementum, 1991, Volume: 376

    Topics: Animals; Apomorphine; Benzazepines; Ketamine; Lithium; Male; Mice; Mice, Inbred C3H; Pentobarbital; Rats; Receptors, Dopamine; Spiperone

1991
[Five new drugs offered in 1970].
    L'union medicale du Canada, 1972, Volume: 101, Issue:2

    Topics: Benzazepines; Carbonates; Dihydroxyphenylalanine; Flurazepam; Hypnotics and Sedatives; Ketamine; Lithium; Mesoridazine

1972
Lithium-ketamine interaction: an animal study of potential clinical and theoretical interest.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Drug Interactions; Ketamine; Lithium; Male; Rats; Rats, Inbred Strains

1982
Ventricular enlargement and the lithium/pilocarpine seizure model: possible explanation for agonistic behaviour.
    The International journal of neuroscience, 2000, Volume: 100, Issue:1-4

    Topics: Acepromazine; Agonistic Behavior; Animals; Anticonvulsants; Ketamine; Lateral Ventricles; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures

2000
The brain matrix and multifocal brain damage following a single injection of ketamine in young adult rats: conspicuous changes in old age.
    Perceptual and motor skills, 2002, Volume: 95, Issue:3 Pt 1

    Topics: Acepromazine; Age Factors; Animals; Brain; Brain Damage, Chronic; Disease Models, Animal; Ketamine; Lithium; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Seizures

2002
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid

2005
Evaluation of behavioral and neurochemical changes induced by ketamine in rats: implications as an animal model of mania.
    Journal of psychiatric research, 2012, Volume: 46, Issue:12

    Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Drug Interactions; Ketamine; Lithium; Male; Protein Carbonylation; Rats; Rats, Wistar; Valproic Acid

2012
Antinociceptive and Anti-Inflammatory Effects of Ketamine and the Relationship to Its Antidepressant Action and GSK3 Inhibition.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Behavior, Animal; Cyclooxygenase 2; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; Ketamine; Lithium; Male; Mice; Nitric Oxide Synthase Type II; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Subcutaneous Tissue; Tumor Necrosis Factor-alpha

2016
Differential effects of lithium isotopes in a ketamine-induced hyperactivity model of mania.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 190

    Topics: Animals; Antimanic Agents; Behavior, Animal; Disease Models, Animal; Isotopes; Ketamine; Lithium; Lithium Chloride; Locomotion; Male; Mania; Rats; Rats, Sprague-Dawley; Treatment Outcome

2020
Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression.
    Translational psychiatry, 2021, 11-25, Volume: 11, Issue:1

    Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder, Treatment-Resistant; Insulin; Ketamine; Lithium; Male; Rats; Rats, Wistar; Rodentia

2021
A letter to the editor, associated with the article entitled "Efficacy and tolerability of combination treatments for major depression: Antidepressants plus second-generation antipsychotics vs esketamine vs lithium" by Vázquez et al. (
    Journal of psychopharmacology (Oxford, England), 2022, Volume: 36, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Depression; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Ketamine; Lithium; Psychopharmacology

2022
Chronic lithium treatment ameliorates ketamine-induced mania-like behavior via the PI3K-AKT signaling pathway.
    Zoological research, 2022, Nov-18, Volume: 43, Issue:6

    Topics: Animals; Antidepressive Agents; Depressive Disorder, Major; Ketamine; Lithium; Lithium Compounds; Male; Mammals; Mania; Mice; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Rodent Diseases; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2022