lipid x has been researched along with lipid a in 47 studies
| Studies (lipid x) | Trials (lipid x) | Recent Studies (post-2010) (lipid x) | Studies (lipid a) | Trials (lipid a) | Recent Studies (post-2010) (lipid a) |
|---|---|---|---|---|---|
| 67 | 0 | 6 | 3,901 | 125 | 1,143 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (57.45) | 18.7374 |
| 1990's | 14 (29.79) | 18.2507 |
| 2000's | 1 (2.13) | 29.6817 |
| 2010's | 5 (10.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brade, H; Feist, W; Flad, HD; Gerdes, J; Kusumoto, S; Musehold, J; Rietschel, HT; Ulmer, AJ; Wang, MH | 1 |
| Golenbock, DT; Lynn, WA; Qureshi, N; Raetz, CR | 1 |
| Macher, I; Schindlmaier, K; Scholz, D; Schütze, E; Vyplel, H | 1 |
| Brade, H; Feist, W; Flad, HD; Rietschel, ET; Ulmer, AJ; Wang, MH | 1 |
| Datta, P; Hunter, RL; Olsen, M; Takayama, K | 1 |
| Danner, RL; Doerfler, ME; Parrillo, JE; Stuetz, P; Van Dervort, AL | 1 |
| Harlan, JM; Kovach, NL; Munford, RS; Raetz, CR; Yee, E | 1 |
| Brade, H; Feist, W; Flad, HD; Herzbeck, H; Kusumoto, S; Rietschel, ET; Ulmer, AJ; Wang, MH | 1 |
| Hawiger, J; Romano, M | 1 |
| Birkland, TP; Cornwell, RD; Golenbock, DT; Proctor, RA | 1 |
| Colwell, DE; Kirkland, TN; McGhee, JR; Michalek, SM; Ziegler, EJ | 1 |
| Gartner, SL; Homer, LD; Kang, YH; Sieckmann, DG; Watson, LP | 1 |
| Proctor, RA | 1 |
| Brade, H; Feist, W; Flad, HD; Kusumoto, S; Loppnow, H; Rietschel, ET; Ulmer, AJ; Wang, MH | 1 |
| Basalka, E; Lam, C; Schütze, E; Walzl, H | 2 |
| Jirsa, RC; Walters, JD | 1 |
| Cady, AB; Kotani, S; Krueger, JM; Kusumoto, S; Shiba, T | 1 |
| Hauser, H; Lipka, G | 1 |
| Akagawa, K; Akamatsu, Y; Amano, F; Nishijima, M | 1 |
| Callahan, KS; Harlan, JM; Maier, RV; Pohlman, TH; Winn, RK | 1 |
| Grabarek, J; Hawiger, J; Timmons, S | 1 |
| Smith, RM | 1 |
| Chung, J; Kugler, E; Macher, I; Sayers, TJ | 1 |
| Raetz, CR; Sibley, CH; Terry, A | 1 |
| Demel, RA; Hauser, H; Lipka, G | 1 |
| Johnson, AG; Ribi, E; Tomai, MA | 1 |
| Golenbock, DT; Proctor, RA; Raetz, CR; Will, JA | 1 |
| Brade, L; Freudenberg, M; Galanos, C; Kusumoto, S; Lüderitz, O; Rietschel, ET; Schade, U; Shiba, T | 1 |
| Ebert, S; Golenbock, DT; Proctor, RA; Will, JA | 1 |
| Dijkstra, J; Mellors, JW; Ryan, JL; Szoka, FC | 1 |
| Burhop, KE; Proctor, RA; Raetz, CR; Will, JA | 1 |
| Brozek, KA; Bulawa, CE; Raetz, CR | 1 |
| Achiwa, K; Ikeda, K; Nakamoto, S; Shimizu, C; Takahashi, T | 1 |
| Anderson, MS; Raetz, CR; Wightman, PD; Zoeller, RA | 1 |
| Akamatsu, Y; Amano, F; Nishijima, M | 1 |
| Akagawa, K; Akamatsu, Y; Amano, F; Nishijima, M; Raetz, CR; Tokunaga, T | 1 |
| Hildebrandt, J; Manthey, CL; Perera, PY; Stütz, PL; Vogel, SN | 1 |
| Carlson, RW; Kelly, TM; Price, NP; Raetz, CR | 1 |
| Flad, HD; Loppnow, H; Rietschel, ET; Ulmer, AJ | 1 |
| Arai, M; Deguchi, N; Kurakata, S; Macindoe, WM; Maeda, H; Miyazaki, H; Mochizuki, T; Ogawa, J; Shiozaki, M; Tatsuta, T | 1 |
| Altobell, LJ; Boyle, NA; Janda, KD; Jones, LH; Lerner, RA; MacDonald, MT; Wentworth, P | 1 |
| Guan, Z; Li, C; Liu, D; Raetz, CR | 1 |
| Finer-Moore, JS; Lee, JK; Metzger, LE; Raetz, CR; Stroud, RM | 1 |
| Barker, JR; Guan, Z; Valdivia, RH; Young, HE; Zhao, J; Zhou, P | 1 |
| Kobayashi, M; Okada, C; Shinoda, A; Tanaka, I; Wakabayashi, H; Yao, M | 1 |
| Cho, J; Lee, CJ; Young, HE; Zhao, J; Zhou, P | 1 |
2 review(s) available for lipid x and lipid a
| Article | Year |
|---|---|
Endotoxin biosynthetic precursors: biologic and therapeutic activities.
Topics: Animals; Endotoxins; Escherichia coli Infections; Glycolipids; Humans; Lipid A; Mice; Mice, Inbred C57BL; Sheep; Ticarcillin | 1989 |
Agonists and antagonists for lipopolysaccharide-induced cytokines.
Topics: Acute-Phase Reaction; Animals; Cytokines; Escherichia coli; Glycolipids; Humans; Leukocytes, Mononuclear; Lipid A; Lipopolysaccharides; Salmonella typhimurium; Structure-Activity Relationship | 1993 |
45 other study(ies) available for lipid x and lipid a
| Article | Year |
|---|---|
Inhibition of endotoxin or lipid A-induced tumor necrosis factor production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.
Topics: Endotoxins; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Glycolipids; Humans; Interferon-gamma; Lipid A; Lipopolysaccharides; Monocytes; Recombinant Proteins; Salmonella; Staphylococcus aureus; Tumor Necrosis Factor-alpha | 1992 |
Lipopolysaccharide-induced stimulation of CD11b/CD18 expression on neutrophils. Evidence of specific receptor-based response and inhibition by lipid A-based antagonists.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; CD18 Antigens; Culture Media, Serum-Free; Cycloheximide; Dactinomycin; Dexamethasone; Disaccharides; Glycolipids; Humans; In Vitro Techniques; Lipid A; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Up-Regulation | 1991 |
C-glycosidic analogues of lipid A and lipid X: synthesis and biological activities.
Topics: Animals; Disaccharides; Glycolipids; Glycosides; Lipid A; Mice; Monosaccharides | 1991 |
Induction and modulation of interleukin 1 production by defined partial structures of lipopolysaccharide.
Topics: Dose-Response Relationship, Drug; Escherichia coli; Glycolipids; Humans; Interleukin-1; Kinetics; Leukocytes, Mononuclear; Lipid A; Lipopolysaccharides | 1991 |
Adjuvant activity of non-ionic block copolymers. V. Modulation of antibody isotype by lipopolysaccharides, lipid A and precursors.
Topics: Adjuvants, Immunologic; Animals; Carbohydrate Sequence; Female; Glycolipids; Immunoglobulin G; Immunoglobulin Isotypes; Lipid A; Lipopolysaccharides; Mice; Molecular Sequence Data; Poloxalene | 1991 |
Antiendotoxin activity of lipid A analogues: requirements of the chemical structure.
Topics: Bacterial Infections; Chemical Phenomena; Chemistry; Endotoxins; Glycolipids; Humans; In Vitro Techniques; Lipid A; Myristic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Superoxides; Trypan Blue | 1990 |
Lipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo.
Topics: Acylation; Animals; Blood; Blotting, Northern; Cytotoxicity Tests, Immunologic; Fibroblasts; Glycolipids; Humans; Lipid A; Lipopolysaccharides; Recombinant Proteins; RNA, Messenger; Salmonella typhimurium; Tumor Necrosis Factor-alpha | 1990 |
Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes.
Topics: Carbohydrate Sequence; Glycolipids; Humans; In Vitro Techniques; Interleukin-1; Lipid A; Lipopolysaccharides; Molecular Sequence Data; Molecular Structure; Monocytes | 1990 |
Interaction of endotoxic lipid A and lipid X with purified human platelet protein kinase C.
Topics: Blood Platelets; Blotting, Western; Calcium; Cell-Free System; Endotoxins; Enzyme Activation; Glycolipids; Humans; In Vitro Techniques; Isoelectric Point; Kinetics; Lipid A; Protein Kinase C | 1990 |
Comparative study of lipopolysaccharide-, lipid IVa-, and lipid X-induced tumor necrosis factor production in murine macrophage-like cell lines.
Topics: Animals; Cell Line; Glycolipids; Lipid A; Lipopolysaccharides; Macrophages; Mice; Tumor Necrosis Factor-alpha | 1990 |
Analysis of the fine specificity and cross-reactivity of monoclonal anti-lipid A antibodies.
Topics: Antibodies, Monoclonal; Antibody Specificity; Antigens, Bacterial; Binding, Competitive; Cross Reactions; Epitopes; Escherichia coli; Glycolipids; Lipid A; Salmonella | 1986 |
Effects of lipopolysaccharide, lipid A, lipid X, and phorbol ester on cultured bovine endothelial cells.
Topics: Animals; Cattle; Cell Adhesion; Cell Line; Cell Survival; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycolipids; Lipid A; Lipopolysaccharides; Microscopy, Electron; Microscopy, Electron, Scanning; Protein Biosynthesis; RNA; Tetradecanoylphorbol Acetate | 1988 |
Interleukin 1 and tumor necrosis factor: studies on the induction by lipopolysaccharide partial structures.
Topics: Glycolipids; Humans; In Vitro Techniques; Interleukin-1; Leukocytes, Mononuclear; Lipid A; Lipopolysaccharides; Tumor Necrosis Factor-alpha | 1989 |
Protection of mice against lethal endotoxemia by lipid X is mediated through inhibition of neutrophil function.
Topics: Animals; Cell Aggregation; Galactosamine; Glucuronidase; Glycolipids; Humans; In Vitro Techniques; Lipid A; Lipopolysaccharides; Lung Diseases; Male; Mice; Mice, Inbred C57BL; Neutrophils; Shock, Septic; Superoxides | 1987 |
Activation of cyclic nucleotide phosphodiesterase by a monosaccharide precursor of Escherichia coli lipid A.
Topics: Calcineurin; Calcium; Calmodulin; Calmodulin-Binding Proteins; Enzyme Activation; Escherichia coli; Glycolipids; Lipid A; Monosaccharides; Phosphoprotein Phosphatases; Structure-Activity Relationship | 1988 |
Somnogenic activities of synthetic lipid A.
Topics: Animals; Body Temperature; Colon; Delta Rhythm; Glycolipids; Lipid A; Male; Rabbits; Sleep; Sleep, REM; Structure-Activity Relationship | 1989 |
Phase behaviour of mixtures of lipid X with phosphatidylcholine and phosphatidylethanolamine.
Topics: Chromatography, Gel; Freeze Fracturing; Freezing; Glycolipids; Hot Temperature; Hydrogen-Ion Concentration; Lipid A; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Microscopy, Electron; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Sonication; Spectrophotometry | 1989 |
Enhancement of O2- generation and tumoricidal activity of murine macrophages by a monosaccharide precursor of Escherichia coli lipid A.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Escherichia coli; Glycolipids; Leukemia, Experimental; Lipid A; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred ICR; Superoxides | 1985 |
A glycolipid precursor of bacterial lipopolysaccharide (lipid X) lacks activity against endothelial cells in vitro and is not toxic in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Escherichia coli; Glycolipids; Goats; Leukocyte Count; Limulus Test; Lipid A; Lipopolysaccharides; Radioimmunoassay; Vibrio cholerae | 1988 |
Modulation of human platelet protein kinase C by endotoxic lipid A.
Topics: Blood Platelets; Blood Proteins; Endotoxins; Enzyme Activation; Escherichia coli; Glycolipids; Humans; Lipid A; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate; Thromboxane-A Synthase; Type C Phospholipases | 1988 |
Pulmonary oxygen toxicity in rats: prevention by pyrogenic diphosphoryl lipid A and potentiation by nontoxic monophosphoryl lipid A and lipid X.
Topics: Animals; Drug Synergism; Endotoxins; Escherichia coli; Glycolipids; Lipid A; Male; Oxygen; Pulmonary Edema; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1988 |
The production of tumor necrosis factor by mouse bone marrow-derived macrophages in response to bacterial lipopolysaccharide and a chemically synthesized monosaccharide precursor.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Glycolipids; Glycoproteins; Interferon-gamma; Lipid A; Lipopolysaccharides; Macrophages; Mice; Neutralization Tests; Tumor Necrosis Factor-alpha | 1987 |
Induction of kappa light chain synthesis in 70Z/3 B lymphoma cells by chemically defined lipid A precursors.
Topics: Animals; B-Lymphocytes; Escherichia coli; Glycolipids; Immunoglobulin kappa-Chains; Lipid A; Lymphoma; Mice; RNA, Messenger; Salmonella typhimurium; Tumor Cells, Cultured | 1988 |
Phase behaviour of lipid X.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry; Chromatography, Gel; Densitometry; Glycolipids; Lipid A; Micelles; Microscopy, Electron; Particle Size; Solubility; Spectrometry, Fluorescence | 1988 |
Glycolipid induced proliferation of lipopolysaccharide hyporesponsive C3H/HeJ splenocytes.
Topics: Animals; Cell Division; Escherichia coli; Glycolipids; Lipid A; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred C3H; Polymyxin B; Salmonella; Spleen | 1988 |
Lipid X ameliorates pulmonary hypertension and protects sheep from death due to endotoxin.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Chemical Phenomena; Chemistry; Endotoxins; Escherichia coli; Escherichia coli Infections; Female; Glycolipids; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Leukocyte Count; Lipid A; Male; Sheep | 1987 |
Endotoxic properties of synthetic pentaacyl lipid A precursor Ib and a structural isomer.
Topics: Animals; Antigens; Endotoxins; Escherichia coli; Fever; Glycolipids; Hemolysis; Lethal Dose 50; Lipid A; Macrophage Activation; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mitosis; Rabbits; Spleen | 1987 |
Elimination and tissue distribution of the monosaccharide lipid A precursor, lipid X, in mice and sheep.
Topics: Animals; Chemical Phenomena; Chemistry; Glycolipids; Half-Life; Lipid A; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Sheep; Tissue Distribution | 1988 |
Modulation of the biological activity of bacterial endotoxin by incorporation into liposomes.
Topics: Animals; Cell Line; Cell Membrane; Cholesterol; Glycolipids; Interleukin-1; Limulus Test; Lipid A; Lipopolysaccharides; Liposomes; Macrophage Activation; Macrophages; Mice; Phagocytosis; Phosphatidylcholines; Phosphatidylserines; Salmonella | 1987 |
Protection of mice against lethal endotoxemia by a lipid A precursor.
Topics: Animals; Drug Administration Schedule; Endotoxins; Escherichia coli; Glycolipids; Lipid A; Mice; Shock, Septic; Structure-Activity Relationship | 1986 |
Biosynthesis of lipid A precursors in Escherichia coli. A membrane-bound enzyme that transfers a palmitoyl residue from a glycerophospholipid to lipid X.
Topics: Acyltransferases; Carbohydrate Conformation; Escherichia coli; Glycolipids; Lipid A; Magnetic Resonance Spectroscopy; Palmitic Acid; Palmitic Acids; Phosphatidic Acids; Protein Precursors; Spectrophotometry, Atomic | 1987 |
Inhibition of lipopolysaccharide-mediated activation of neutrophils with monosaccharide derivatives of lipid A.
Topics: Animals; Galactosamine; Glycolipids; Humans; In Vitro Techniques; Lipid A; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Neutrophils; Oxygen | 1987 |
Lipid A and related compounds. XI. New, efficient synthesis of lipid X.
Topics: Chemical Phenomena; Chemistry; Glycolipids; Lipid A | 1987 |
Accumulation of lysophosphatidylinositol in RAW 264.7 macrophage tumor cells stimulated by lipid A precursors.
Topics: Animals; Calcium; Glycolipids; Lipid A; Lysophospholipids; Macrophages; Membrane Lipids; Phospholipids; Prostaglandins; Tumor Cells, Cultured | 1987 |
A monosaccharide precursor of Escherichia coli lipid A has the ability to induce tumor-cytotoxic factor production by a murine macrophage-like cell line, J774.1.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Glycolipids; Glycoproteins; Lipid A; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Monosaccharides; Neoplasms, Experimental; Tumor Necrosis Factor-alpha | 1986 |
Macrophage activation by monosaccharide precursors of Escherichia coli lipid A.
Topics: Animals; Cytotoxicity, Immunologic; Dinoprostone; Escherichia coli; Glycolipids; Lipid A; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Peptones; Prostaglandins E | 1985 |
Induction of early gene expression in murine macrophages by synthetic lipid A analogs with differing endotoxic potentials.
Topics: Animals; Carbohydrate Sequence; Endotoxins; Female; Gene Expression; Glycolipids; In Vitro Techniques; Interleukin-1; Lipid A; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C3H; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Structure-Activity Relationship; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 1993 |
Biosynthesis of a structurally novel lipid A in Rhizobium leguminosarum: identification and characterization of six metabolic steps leading from UDP-GlcNAc to 3-deoxy-D-manno-2-octulosonic acid2-lipid IVA.
Topics: Acetates; Acyltransferases; Amidohydrolases; Carbohydrate Sequence; Glycolipids; Lipid A; Models, Biological; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Phosphates; Phosphotransferases (Alcohol Group Acceptor); Rhizobium leguminosarum; Sugar Acids; Transferases | 1994 |
Syntheses of 1-O-carboxyalkyl GLA-60 analogues.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Cells, Cultured; Escherichia coli; Glucosides; Glycolipids; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Prednisolone; Salmonella; Tumor Necrosis Factor-alpha | 1996 |
Active immunization with a glycolipid transition state analogue protects against endotoxic shock.
Topics: Animals; Antibodies; Diphosphonates; Escherichia coli; Glycoconjugates; Glycolipids; Hemocyanins; Lipid A; Mice; Molecular Mimicry; Shock, Septic; Tumor Necrosis Factor-alpha; Vaccination; Vaccines, Synthetic | 2002 |
Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli.
Topics: Acyltransferases; Arabidopsis; Base Sequence; Chromosome Mapping; DNA, Plant; Escherichia coli; Gene Knockdown Techniques; Gene Knockout Techniques; Genes, Plant; Glycolipids; Lipid A; Metabolic Networks and Pathways; Mitochondria; Molecular Structure; Mutation; Plants, Genetically Modified; Species Specificity | 2011 |
LpxI structures reveal how a lipid A precursor is synthesized.
Topics: Amino Acid Sequence; Caulobacter crescentus; Crystallization; DNA Mutational Analysis; Glycolipids; Isoenzymes; Lipid A; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Conformation; Protein Folding; Pyrophosphatases; Ultracentrifugation | 2012 |
Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis.
Topics: Biosynthetic Pathways; Chlamydia trachomatis; Escherichia coli; Gene Library; Genetic Testing; Glycolipids; Lipid A; Pyrophosphatases; Sequence Homology, Amino Acid | 2016 |
Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa.
Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Glycolipids; Hydrophobic and Hydrophilic Interactions; Lipid A; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Pyrophosphatases | 2016 |
Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis.
Topics: Biocatalysis; Carbohydrate Metabolism; Crystallization; Crystallography, X-Ray; Glycolipids; Haemophilus influenzae; Hydrolysis; Lipid A; Models, Molecular; Pyrophosphatases; Substrate Specificity | 2016 |