linsidomine has been researched along with tyrosine in 91 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (12.09) | 18.2507 |
| 2000's | 65 (71.43) | 29.6817 |
| 2010's | 15 (16.48) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duran, D; Horwitz, J; Ischiropoulos, H | 1 |
| Haddad, IY; Matalon, S; Zhu, S | 1 |
| Hemmens, B; Leopold, E; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER | 1 |
| Brady, T; D'Ambrosio, SM; Oberyszyn, TM; Robertson, FM; Ross, MS | 1 |
| Holm, P; Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E | 1 |
| Mayer, B; Pfeiffer, S | 1 |
| Goss, SP; Hogg, N; Kalyanaraman, B | 1 |
| Celan, I; Chazotte, L; Mower, HF; Ohshima, H; Pignatelli, B | 1 |
| Maeda, S; Saeki, M | 1 |
| Grisham, MB; Koyama, S; Robbins, RA; Sato, E; Simpson, KL | 2 |
| Beckman, JS; Crow, JP; MacMillan-Crow, LA; Takakura, K | 1 |
| Basiouny, KF; Crow, JP; Matalon, S; Zhu, S | 1 |
| Kamisaki, Y; Maeda, S; Saeki, M | 1 |
| Holbrook, NJ; Klotz, LO; Schieke, SM; Sies, H | 1 |
| Deby-Dupont, G; Hans, P; Kohnen, S; Lamy, M; Mathy-Hartert, M; Mouithys-Mickalad, A | 1 |
| Daiber, A; Herold, S; Namgaladze, D; Peterson, JA; Schöneich, C; Ullrich, V | 1 |
| Hodges, GR; Ingold, KU; Marwaha, J; Paul, T | 1 |
| Camhi, SL; Koyama, S; Nelson, DK; Robbins, RA; Sato, E | 1 |
| Akaike, A; Ibi, M; Kaneko, S; Katsuki, H; Kume, T; Shimazu, S; Shirakawa, H; Takenaka, C; Tomita, M | 1 |
| Blanchard, B; Ducrocq, C; Servy, C | 1 |
| Douglass, LW; Ledbetter, TK; Paape, MJ | 1 |
| Camhi, SL; Hoyt, JC; Nelson, DK; Robbins, RA; Robinson, VK; Sato, E | 1 |
| Berrih-Aknin, S; Gaudry-Talarmain, YM; Moulian, N; Serraf, A; Truffault, F | 1 |
| Feix, J; Hogg, N; Joseph, J; Kalyanaraman, B; Zhang, H | 1 |
| Bian, K; Murad, F | 1 |
| Gupta, MP; Hart, CM; Knepler, JL; Ober, MD; Patterson, C; Pavalko, F; Taher, LN | 1 |
| Ducrocq, C; Gaudry-Talarmain, YM; Guermonprez, L | 1 |
| Hewett, SJ; Trackey, JL; Uliasz, TF | 1 |
| Bridges, CC; El-Sherbeny, A; Ganapathy, V; Ola, MS; Prasad, PD; Smith, SB | 1 |
| Choi, CR; Choi, JW; Jang, ES; Ju, C; Kim, HC; Kim, WK; Ko, KH; Shin, CY | 1 |
| Kato, Y; Maruyama, W; Naoi, M; Sato, Y; Shamoto-Nagai, M; Tanaka, M; Yamamoto, T; Yi, H | 1 |
| Folkerts, G; Habernickel, J; Muijsers, RB; Nijkamp, FP; Postma, DS; van der Veeken, A | 1 |
| da Rocha, FA; de Brum-Fernandes, AJ | 1 |
| Choi, JJ; Kim, HC; Kim, WK; Ko, KH; Kong, MY; Lee, SJ | 1 |
| Choi, JS; Chung, HY; Kim, AR; Kim, JE; Zou, Y | 1 |
| Brimer, CM; Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV; Zborek, A | 1 |
| Drapier, JC; Soum, E | 1 |
| Bao, F; DeWitt, DS; Liu, D; Prough, DS | 1 |
| Burch, P; Heintz, NH; Janssen-Heininger, Y; Schellekens, H; Warner, L; Yuan, Z | 1 |
| Clements, MK; Hanson, AJ; Nelson-Overton, LK; Quinn, MT; Rohn, TT; Siemsen, DW; Swain, SD | 1 |
| Denicola, A; Radi, R; Thomson, L | 1 |
| Aoyagi, K; Cho, EJ; Rhyu, DY; Yokozawa, T | 1 |
| Hiramoto, K; Kikugawa, K; Ohkawa, T | 1 |
| Antunes, E; De Nucci, G; Marcondes, S; Moreira, J; Thomazzi, SM | 1 |
| Ayuk, PT; Glazier, JD; Greenwood, SL; Khullar, S; McCord, N | 1 |
| Choi, JB; Igarashi, Y; Kashiwagi, A; Kawamori, R; Maegawa, H; Mineki, R; Murayama, K; Nomiyama, T; Ogihara, T; Taka, H; Tanaka, Y; Uchida, T; Uchino, H; Watada, H | 1 |
| Crow, JP; Mogal, A; Nielsen, VG; Parks, DA; Zhou, F | 1 |
| Dikalov, S; Greilberger, J; Oettl, K; Reibnegger, G | 1 |
| Brugnara, C; De Franceschi, L; Di Stasi, AM; Mallozzi, C | 1 |
| Bottari, SP; Garrido, MR; Levy, P; Pinzar, E; Wang, T; Xu, W | 1 |
| Austin, RC; Dickhout, JG; Hossain, GS; Lhoták, S; Pozza, LM; Zhou, J | 1 |
| Aviram, M; Soliman, K; Szuchman, A; Tamir, S; Vaya, J | 1 |
| Barbar, EJ; Deeb, RS; Gross, SS; Hajjar, DP; Hao, G; Lainé, M; Qiu, JH; Resnick, B; Upmacis, RK | 1 |
| Aureliano, M; Gutiérrez-Merino, C; Ramos, S; Tiago, T | 1 |
| Aureliano, M; Gutiérrez-Merino, C; Martín-Romero, FJ; Simão, S; Tiago, T | 1 |
| Doke, N; Kawakita, K; Saito, S; Yamamoto-Katou, A; Yoshioka, H | 1 |
| El Bohi, K; Fujita, S; Ishizuka, M; Kazusaka, A; Muzandu, K; Sakamoto, KQ; Shaban, Z | 1 |
| Bar-Shai, M; Reznick, AZ | 1 |
| Pollard, SE; Spencer, JP; Whiteman, M | 1 |
| Christopher, TA; Coletti, C; Gao, E; Hu, A; Koch, W; Lopez, BL; Ma, XL; Tao, L; Wang, Y | 1 |
| Idell, S; Liu, MC; Yasuda, S | 1 |
| Carbonneau, MA; Fouret, G; Leger, CL; Torres-Rasgado, E | 1 |
| Hall, ED; Singh, IN; Sullivan, PG | 1 |
| Dairou, J; Dupret, JM; Haddad, I; Mary, J; Noiran, J; Petit, E; Pluvinage, B; Rodrigues-Lima, F; Vinh, J | 1 |
| Black, SA; Ferguson, SS; Pholpramool, C; Pinthong, M; Ribeiro, FM; Rylett, RJ | 1 |
| Ariz, I; Arrese-Igor, C; Auzmendi, I; González, EM; Larrainzar, E; Moran, JF; Urarte, E | 1 |
| Davies, MJ; Kennett, EC | 1 |
| Ashki, N; Bao, F; Hayes, KC | 1 |
| Asatryan, L; Gallaher, TK; Hamilton, RT; Hsiai, TK; Isas, JM; Nilsen, JT; Sawamura, T | 1 |
| Gao, Z; Lu, N; Zhang, Y | 1 |
| Arai, T; Fujieda, S; Kobayashi, S; Kuramochi, K; Nakajima, M; Nakazaki, A; Ohnishi, K; Saitoh, Y; Sugawara, F; Takeuchi, T; Watanabe, N | 1 |
| Belaaouaj, A; Crouch, EC; Gao, Z; Kirk, M; Matalon, S; McDonald, B; Shrestha, K; Smith, K; Waldheuser, S | 1 |
| Boos, N; Hottiger, M; Poveda, L; Wuertz, K | 1 |
| Hall, ED; Singh, IN; Xiong, Y | 1 |
| Barbosa-Sicard, E; Brandes, RP; Braun, T; Fleming, I; Frömel, T; Hammock, BD; Keserü, B; Krüger, M; Morisseau, C | 1 |
| Antunes, E; Cardoso, MH; De Nucci, G; Lilla, S; Marcondes, S; Morganti, RP; Murad, F | 1 |
| Bi, L; Chen, H; Li, Y; Liu, X; Mao, Z; Qu, L; Xiong, J | 1 |
| Chen, ML; Fan, Q; Ge, YG; Irwin, MG; Liu, SH; Liu, Y; Wang, LF; Wang, W; Xia, Z; Yang, XC; Zhang, LK | 1 |
| Domingo de Miguel, E; Iraburu, MJ; López-Zabalza, MJ; Mòdol, T; Natal, C; Pérez de Obanos, MP | 1 |
| Chen, CC; Hsu, YJ; Lee, TM | 1 |
| Delledonne, M; Gaupels, F; Spiazzi-Vandelle, E; Yang, D | 1 |
| Enerson, BE; Lawton, MP; Peters, D; Sheth, CM; Weaver, JL | 1 |
| Gao, Z; Lu, N; Zhang, Y; Zhao, Y | 1 |
| Hemanth Kumar, K; Khanum, F; Pal, A; Tamatam, A | 1 |
| Barroso, JB; Begara-Morales, JC; Carreras, A; Chaki, M; Corpas, FJ; López-Jaramillo, J; Sánchez-Calvo, B; Valderrama, R | 1 |
| Alameda, F; Alcolea, D; Boada, M; Bosch-Morató, M; Elosúa, R; Eraso-Pichot, A; Fernández-Busquets, X; Fortea, J; Guivernau, B; Ill-Raga, G; Lleó, A; Muñoz, FJ; Nuñez, L; Paez, A; Palomer, E; Ramos-Fernández, E; Román-Dégano, I; Tajes, M; Valverde, MA | 1 |
| Al-Hashimi, F; Al-Shboul, OA; Al-Shehabat, M; Mohammad, M; Mustafa, A; Yousef, A | 1 |
| Akbarali, HI; Gade, A; Hashimoto, A; Kang, M | 1 |
| Arnhold, J; Flemmig, J; Koyani, CN; Malle, E | 1 |
| Gao, W; Gao, Z; Li, H; Zhao, J | 1 |
1 review(s) available for linsidomine and tyrosine
| Article | Year |
|---|---|
Use of recombinant iron-superoxide dismutase as a marker of nitrative stress.
Topics: Antibodies; Biomarkers; Enzyme Activation; Immunohistochemistry; Molsidomine; Nitro Compounds; Nitrosation; Oxidative Stress; Recombinant Proteins; Serum Albumin, Bovine; Superoxide Dismutase; Tyrosine | 2008 |
1 trial(s) available for linsidomine and tyrosine
| Article | Year |
|---|---|
Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans.
Topics: Aged; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Ischemic Postconditioning; Leukocyte Count; Male; Malondialdehyde; Middle Aged; Molsidomine; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tyrosine; Ventricular Function, Left | 2011 |
89 other study(ies) available for linsidomine and tyrosine
| Article | Year |
|---|---|
Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells.
Topics: Animals; Dihydroxyphenylalanine; Molsidomine; Nitrates; Oxidation-Reduction; PC12 Cells; Rats; Tyrosine | 1995 |
Nitration of surfactant protein A (SP-A) tyrosine residues results in decreased mannose binding ability.
Topics: Animals; Binding Sites; Free Radical Scavengers; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lipid Peroxidation; Liposomes; Mannose; Molsidomine; Nitrates; Nitric Oxide; Oxidative Stress; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Superoxides; Tetranitromethane; Tyrosine | 1996 |
Interference of carboxy-PTIO with nitric oxide- and peroxynitrite-mediated reactions.
Topics: Animals; Benzoates; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Free Radical Scavengers; Imidazoles; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Serum Albumin, Bovine; Swine; Tyrosine | 1997 |
Sensitivity of human hepatocytes in culture to reactive nitrogen intermediates.
Topics: Cells, Cultured; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Molsidomine; Nitrites; Nitrogen; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Tyrosine | 1997 |
Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine.
Topics: Molsidomine; Nitric Oxide; Oxygen; Penicillamine; Superoxides; Triazoles; Tyrosine | 1998 |
Lack of tyrosine nitration by peroxynitrite generated at physiological pH.
Topics: Carbon Dioxide; Free Radicals; Hydrogen-Ion Concentration; Models, Chemical; Molsidomine; Nitrates; Nitrogen Oxides; Spermine; Tyrosine; Xanthine Oxidase | 1998 |
The effect of alpha-tocopherol on the nitration of gamma-tocopherol by peroxynitrite.
Topics: Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Liposomes; Molsidomine; Nitrates; Oxidants; Pentetic Acid; Stereoisomerism; Tyrosine; Vitamin E | 1999 |
Analysis of 3-nitrotyrosine in biological fluids and protein hydrolyzates by high-performance liquid chromatography using a postseparation, on-line reduction column and electrochemical detection: results with various nitrating agents.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Hypochlorous Acid; Indicators and Reagents; Molsidomine; Nitrates; Nitrites; Nitrogen Oxides; Serum Albumin, Bovine; Sodium Nitrite; Spectrophotometry, Ultraviolet; Spermine; Tyrosine | 1999 |
p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite.
Topics: Crk-Associated Substrate Protein; Humans; Molsidomine; Neuroblastoma; Nitrates; Nitric Oxide Donors; Oxidants; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured; Tyrosine | 1999 |
Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro.
Topics: Chemokine CCL5; Chemotaxis; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrazines; Interleukin-5; Leukotriene B4; Molsidomine; Nitrates; Nitric Oxide; Nitrogen; Pteridines; Reactive Oxygen Species; Superoxides; Tyrosine; Xanthine | 1999 |
Rapid and irreversible inactivation of protein tyrosine phosphatases PTP1B, CD45, and LAR by peroxynitrite.
Topics: Aniline Compounds; Anions; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Leukocyte Common Antigens; Models, Molecular; Molsidomine; Nitrates; Nitric Oxide; Nitroso Compounds; Organophosphates; Organophosphorus Compounds; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; S-Nitrosoglutathione; Superoxide Dismutase; Tyrosine | 1999 |
Reactive nitrogen and oxygen species attenuate interleukin- 8-induced neutrophil chemotactic activity in vitro.
Topics: Chemotaxis, Leukocyte; Humans; Interleukin-8; Leukotriene B4; Molsidomine; Neutrophils; Nitrates; Nitric Oxide Donors; Tyrosine | 2000 |
Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages.
Topics: Carbon Dioxide; Cells, Cultured; Enzyme Activation; Epithelial Cells; Humans; Hypercapnia; Lipid Metabolism; Lipopolysaccharides; Macrophages, Alveolar; Mass Spectrometry; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Respiratory Distress Syndrome; Tyrosine | 2000 |
Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Carbachol; Genistein; Humans; Molsidomine; Neuroblastoma; Nitrates; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2000 |
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.
Topics: Androstadienes; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Molsidomine; Morpholines; Nitrates; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Skin; Time Factors; Tyrosine; Tyrphostins; Wortmannin | 2000 |
Effects of propofol on endothelial cells subjected to a peroxynitrite donor (SIN-1).
Topics: Anesthetics, Intravenous; Cell Culture Techniques; Cell Death; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Molsidomine; Nitrates; Nitric Oxide Donors; Propofol; Tyrosine | 2000 |
Nitration and inactivation of cytochrome P450BM-3 by peroxynitrite. Stopped-flow measurements prove ferryl intermediates.
Topics: Animals; Bacillus; Bacterial Proteins; Binding Sites; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dithiothreitol; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Inhibitory Concentration 50; Iron; Mass Spectrometry; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Molsidomine; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide Donors; Nitrogen; Oxygen; Superoxide Dismutase; Temperature; Time Factors; Tyrosine; Uric Acid | 2000 |
A novel procedure for generating both nitric oxide and superoxide in situ from chemical sources at any chosen mole ratio. First application: tyrosine oxidation and a comparison with preformed peroxynitrite.
Topics: Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Spermine; Superoxides; Tyrosine | 2000 |
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.
Topics: Blood; Cell Line; Cell Movement; Complement Activation; Deferoxamine; Dithiothreitol; Embryo, Mammalian; Fibroblasts; Fibronectins; Humans; Lung; Molsidomine; Nitrates; Nitric Oxide Donors; Nitrogen; Reactive Oxygen Species; Reducing Agents; Superoxides; Tyrosine; Xanthine Oxidase | 2001 |
Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity.
Topics: Animals; Animals, Newborn; Cell Survival; Coculture Techniques; Corpus Striatum; Dihydrolipoamide Dehydrogenase; Dopamine; Mesencephalon; Molsidomine; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide Donors; Nitroarginine; Nitroso Compounds; Organ Culture Techniques; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine; Tyrosine 3-Monooxygenase | 2001 |
Chemical evaluation of compounds as nitric oxide or peroxynitrite donors using the reactions with serotonin.
Topics: Aerobiosis; Chromatography, High Pressure Liquid; Copper; Glutathione; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; S-Nitrosoglutathione; Serotonin; Tyrosine | 2001 |
Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase, and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells.
Topics: Aniline Compounds; Animals; Antioxidants; Blotting, Western; Cattle; Cell Death; Enzyme Inhibitors; Epithelial Cells; Female; Free Radical Scavengers; Histidine; L-Lactate Dehydrogenase; Lipopolysaccharides; Mammary Glands, Animal; Molsidomine; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 2001 |
Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro.
Topics: Animals; Base Sequence; Cell Line; DNA Primers; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Hydrazines; Lung; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; RNA, Messenger; Tyrosine | 2001 |
In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation.
Topics: Annexin A5; Apoptosis; Cells, Cultured; Child, Preschool; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; In Situ Nick-End Labeling; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Stromal Cells; Superoxide Dismutase; Superoxides; T-Lymphocytes; Thymus Gland; Tyrosine | 2001 |
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution.
Topics: Bicarbonates; Cyclic N-Oxides; Free Radicals; Hydroxyl Radical; Lipid Bilayers; Liposomes; Mass Spectrometry; Membranes, Artificial; Molsidomine; Nitrates; Nitrosation; Oxidation-Reduction; Solutions; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spin Labels; Tyrosine; Water | 2001 |
Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs.
Topics: Animals; Endothelium, Vascular; Immunoblotting; Immunoenzyme Techniques; Lipopolysaccharides; Liver; Lung; Macrophages; Male; Molsidomine; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Sprague-Dawley; Spleen; Superoxides; Tyrosine | 2001 |
Peroxynitrite causes endothelial cell monolayer barrier dysfunction.
Topics: Actins; Animals; beta Catenin; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Pulmonary Artery; Reactive Oxygen Species; Superoxide Dismutase; Swine; Trans-Activators; Tyrosine | 2001 |
Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants.
Topics: Acetates; Acetylcholine; Animals; Antioxidants; Biological Transport; Carbon Radioisotopes; Choline; Choline O-Acetyltransferase; Drug Interactions; Molsidomine; Nitrates; Oxidants; Reducing Agents; Torpedo; Tyrosine; Uric Acid | 2001 |
SIN-1-induced cytotoxicity in mixed cortical cell culture: peroxynitrite-dependent and -independent induction of excitotoxic cell death.
Topics: Animals; Astrocytes; Catalase; Cell Death; Cells, Cultured; Cerebral Cortex; Free Radical Scavengers; Mice; Molsidomine; Neurons; Neurotoxins; Peroxynitrous Acid; Superoxide Dismutase; Tyrosine | 2001 |
Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells.
Topics: Animals; Antioxidants; Ascorbic Acid; Carrier Proteins; Cell Line; Diabetes Mellitus; Dose-Response Relationship, Drug; Glutathione; Humans; Immunohistochemistry; Membrane Glycoproteins; Membrane Transport Proteins; Methylene Blue; Mice; Mice, Inbred ICR; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Pigment Epithelium of Eye; Protein Synthesis Inhibitors; Taurine; Time Factors; Tyrosine | 2001 |
Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose.
Topics: Adjuvants, Immunologic; Animals; Astrocytes; Brain; Brain Ischemia; Cell Death; Cytokines; Dehydroepiandrosterone; Enzyme Inhibitors; Free Radical Scavengers; Glioma; Glucose; Herbicides; Humans; Interferon-gamma; Lipopolysaccharides; Metalloporphyrins; Molsidomine; Neurons; Nitric Oxide; Oxidative Stress; Paraquat; Peroxynitrous Acid; Superoxide Dismutase; Tumor Cells, Cultured; Tyrosine | 2001 |
Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells.
Topics: Adenosine Triphosphate; Apoptosis; Cell Death; Cysteine Proteinase Inhibitors; Dopamine; Electron Transport Complex I; Humans; Mitochondria; Molsidomine; NADH, NADPH Oxidoreductases; Nitric Oxide Donors; Oligopeptides; Peroxynitrous Acid; Subcellular Fractions; Tumor Cells, Cultured; Tyrosine | 2002 |
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness.
Topics: Acetylcholine; Animals; Bronchi; Bronchial Hyperreactivity; Inflammation; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molsidomine; Peroxynitrous Acid; Trachea; Tyrosine | 2002 |
Evidence that peroxynitrite affects human osteoblast proliferation and differentiation.
Topics: Alkaline Phosphatase; Catalase; Cell Differentiation; Cell Division; Cells, Cultured; Humans; Interferon-gamma; Interleukin-1; Molsidomine; Nitric Oxide Donors; Nitrites; Osteoblasts; Peroxynitrous Acid; Recombinant Proteins; Superoxide Dismutase; Thymidine; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Ciclopirox prevents peroxynitrite toxicity in astrocytes by maintaining their mitochondrial function: a novel mechanism for cytoprotection by ciclopirox.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cell Cycle; Cell Death; Cells, Cultured; Ciclopirox; Flow Cytometry; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Molsidomine; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Pyridones; Rats; Rats, Sprague-Dawley; Rhodamines; Serum Albumin, Bovine; Superoxides; Tyrosine | 2002 |
Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea.
Topics: Brassica; Coumaric Acids; Free Radical Scavengers; Lipid Peroxidation; Lipoproteins, LDL; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Serum Albumin, Bovine; Superoxides; Tyrosine | 2002 |
Comparison of uric acid and ascorbic acid in protection against EAE.
Topics: Albumins; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Cell Line; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Immunohistochemistry; Iron; Lipid Peroxidation; Mice; Molsidomine; Myelin Sheath; Nitric Oxide; Oxygen; Peroxynitrous Acid; Rhodamines; Time Factors; Tyrosine; Uric Acid | 2002 |
Nitric oxide and peroxynitrite promote complete disruption of the [4Fe-4S] cluster of recombinant human iron regulatory protein 1.
Topics: Aconitate Hydratase; Blotting, Western; Conserved Sequence; Electrophoretic Mobility Shift Assay; Ferrozine; Humans; Iron Regulatory Protein 1; Iron-Sulfur Proteins; Mercaptoethanol; Molsidomine; Nitrates; Nitric Oxide; Peroxynitrous Acid; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 2003 |
Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin.
Topics: 2,4-Dinitrophenol; Animals; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Immunohistochemistry; Male; Metalloporphyrins; Microdialysis; Molsidomine; Neurons; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Time Factors; Tyrosine | 2003 |
Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide.
Topics: Animals; Catalase; Cell Cycle; Cells, Cultured; Cyclin D1; Epithelial Cells; Fluoresceins; Gene Expression Regulation; Hydrogen Peroxide; Mice; Molsidomine; Nitric Oxide Donors; Nitrogen Dioxide; Oxidants; Pulmonary Alveoli; Signal Transduction; Superoxide Dismutase; Transcription Factor AP-1; Tyrosine | 2003 |
Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses.
Topics: Actins; Chemotaxis; Dimerization; Dose-Response Relationship, Drug; Humans; Molsidomine; Neutrophil Activation; Neutrophils; Nitric Oxide Donors; Peroxynitrous Acid; Phagocytosis; Reactive Oxygen Species; Respiratory Burst; Tyrosine | 2003 |
The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity.
Topics: Animals; Antioxidants; Biochemistry; Blotting, Western; Chromatography, High Pressure Liquid; Disulfides; Dose-Response Relationship, Drug; Glutathione; Macrophages; Models, Chemical; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Oxygen; Peroxynitrous Acid; Sulfhydryl Compounds; Time Factors; Trypanosoma cruzi; Tyrosine | 2003 |
Protective activity of (-)-epicatechin 3-O-gallate against peroxynitrite-mediated renal damage.
Topics: Animals; Antioxidants; Caspases; Catechin; Cell Cycle; Cell Line; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione; Glutathione Peroxidase; Kidney; Lipid Peroxides; Lipopolysaccharides; LLC-PK1 Cells; Male; Molsidomine; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Rhodamines; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine | 2003 |
Effects of oxygen on the reactivity of nitrogen oxide species including peroxynitrite.
Topics: Anaerobiosis; Electron Spin Resonance Spectroscopy; Glutathione; Molsidomine; Morpholines; Nitric Oxide; Nitrogen Oxides; Nitrosamines; Nitrous Oxide; Oxygen; Peroxynitrous Acid; S-Nitrosoglutathione; Solutions; Tyrosine | 2004 |
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine | 2004 |
Nitric oxide and superoxide impair human placental amino acid uptake and increase Na+ permeability: implications for fetal growth.
Topics: Amino Acids; Biological Transport; Female; Fetal Growth Retardation; Free Radicals; Humans; Infant, Newborn; Microvilli; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Placenta; Pregnancy; Sodium; Subcellular Fractions; Superoxides; Time Factors; Trophoblasts; Tyrosine | 2004 |
Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1.
Topics: 3T3-L1 Cells; Animals; Binding Sites; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Receptor Substrate Proteins; Mice; Molsidomine; Nitrates; Peroxynitrous Acid; Phosphoproteins; Protein Binding; Rats; Tyrosine | 2004 |
Peroxynitrite decreases hemostasis in human plasma in vitro.
Topics: Blood Coagulation Factors; Blotting, Western; Coagulants; Dose-Response Relationship, Drug; Factor X; Hemostasis; Humans; In Vitro Techniques; Molsidomine; Nitric Oxide Donors; Partial Thromboplastin Time; Peroxynitrous Acid; Plasma; Protein C; Prothrombin Time; Superoxide Dismutase; Thrombelastography; Tyrosine | 2004 |
Interference of 7,8-dihydroneopterin with peroxynitrite-mediated reactions.
Topics: Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxylation; Luminescent Measurements; Molsidomine; Neopterin; Oxidation-Reduction; Peroxynitrous Acid; Piperidines; Salicylic Acid; Spectrometry, Fluorescence; Superoxides; Tyrosine | 2004 |
Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr.
Topics: Down-Regulation; Enzyme Activation; Erythrocytes; Humans; K Cl- Cotransporters; Molsidomine; Peroxynitrous Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; src-Family Kinases; Symporters; Tyrosine | 2005 |
Angiotensin II induces tyrosine nitration and activation of ERK1/2 in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molsidomine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Rats; Receptor, Angiotensin, Type 1; Tyrosine | 2005 |
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis.
Topics: Animals; Aorta; Apolipoproteins E; Apoptosis; Atherosclerosis; Calcium; Cells, Cultured; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endothelium, Vascular; Female; Homeostasis; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Peroxynitrous Acid; Superoxides; Tyrosine; Umbilical Veins | 2005 |
Exogenous N-linoleoyl tyrosine marker as a tool for the characterization of cellular oxidative stress in macrophages.
Topics: Animals; Cell-Free System; Cells, Cultured; Copper; Hypochlorous Acid; Linoleic Acid; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molsidomine; Oxidative Stress; Tyrosine | 2006 |
Heme catalyzes tyrosine 385 nitration and inactivation of prostaglandin H2 synthase-1 by peroxynitrite.
Topics: Amino Acid Sequence; Animals; Apoenzymes; Binding Sites; Catalysis; Chromatography, Ion Exchange; Cyclooxygenase 1; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Heme; Hemin; Holoenzymes; Hydroxyl Radical; Male; Models, Chemical; Molecular Sequence Data; Molsidomine; Peroxynitrous Acid; Seminal Vesicles; Sheep; Tyrosine | 2006 |
Peroxynitrite induces F-actin depolymerization and blockade of myosin ATPase stimulation.
Topics: Actins; Animals; Calorimetry, Differential Scanning; Enzyme Activation; Molsidomine; Myosins; Oxidation-Reduction; Peroxynitrous Acid; Protein Denaturation; Protein Folding; Rabbits; Temperature; Tyrosine | 2006 |
Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Catalysis; Cysteine; Dose-Response Relationship, Drug; Enzyme Stability; Magnesium; Molsidomine; Myosin Subfragments; Oxidation-Reduction; Peroxynitrous Acid; Protein Folding; Rabbits; Skeletal Muscle Myosins; Temperature; Time Factors; Tyrosine | 2006 |
Peroxynitrite generation and tyrosine nitration in defense responses in tobacco BY-2 cells.
Topics: Algal Proteins; Aniline Compounds; Antibodies, Anti-Idiotypic; Cells, Cultured; Cyclic GMP; Fluoresceins; Fungal Proteins; Molsidomine; Nicotiana; Nitric Oxide; Peroxynitrous Acid; Phytophthora; Proteins; Reactive Oxygen Species; Superoxides; Tyrosine; Uric Acid | 2006 |
Effect of lycopene and beta-carotene on peroxynitrite-mediated cellular modifications.
Topics: Animals; Antioxidants; beta Carotene; Carotenoids; Cell Line; Cell Survival; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Lycopene; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Tyrosine | 2006 |
Reactive nitrogen species induce nuclear factor-kappaB-mediated protein degradation in skeletal muscle cells.
Topics: Animals; Antioxidants; Cells, Cultured; Metalloendopeptidases; Molsidomine; Muscle Cells; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; NF-kappa B; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Rats; Reactive Nitrogen Species; Tyrosine; Ubiquitin | 2006 |
Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling.
Topics: Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Hesperidin; Humans; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Signal Transduction; Tyrosine | 2006 |
Thioredoxin reduces post-ischemic myocardial apoptosis by reducing oxidative/nitrative stress.
Topics: Animals; Apoptosis; Male; Mice; Molsidomine; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Superoxides; Thioredoxins; Tyrosine | 2006 |
Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: identification of SULT1A3 as the enzyme responsible.
Topics: Arylsulfotransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Dopamine; Humans; Kinetics; Molsidomine; Sulfotransferases; Tyrosine | 2007 |
Peroxynitrite mild nitration of albumin and LDL-albumin complex naturally present in plasma and tyrosine nitration rate-albumin impairs LDL nitration.
Topics: Antioxidants; Atherosclerosis; Humans; Lipoproteins, LDL; Molsidomine; Nitric Oxide Donors; Nitrogen Dioxide; Oxidation-Reduction; Peroxynitrous Acid; Serum Albumin; Tyrosine | 2007 |
Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers.
Topics: Aldehydes; Animals; Cell Respiration; Cerebral Cortex; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Transport Complex I; Free Radical Scavengers; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitochondria; Molsidomine; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Penicillamine; Peroxynitrous Acid; Protein Carbonylation; Spin Labels; Tyrosine | 2007 |
Nitration of a critical tyrosine residue in the allosteric inhibitor site of muscle glycogen phosphorylase impairs its catalytic activity.
Topics: Allosteric Regulation; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glycogen Phosphorylase, Muscle Form; Mice; Models, Molecular; Molsidomine; Muscle Fibers, Skeletal; Muscle, Skeletal; Nitric Oxide Donors; Peroxynitrous Acid; Protein Structure, Tertiary; Tyrosine | 2007 |
Activity and subcellular trafficking of the sodium-coupled choline transporter CHT is regulated acutely by peroxynitrite.
Topics: Animals; Biotinylation; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cell Membrane; Choline; Cholinergic Agents; Culture Media; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hemicholinium 3; Humans; Inhibitory Concentration 50; Kidney; Kinetics; L-Lactate Dehydrogenase; Luminescence; Membrane Potentials; Membrane Transport Proteins; Molsidomine; Neuroblastoma; Nitrogen; Oxidative Stress; Peroxynitrous Acid; Protein Transport; Rats; Sodium; Subcellular Fractions; Time Factors; Transfection; Tyrosine | 2008 |
Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid.
Topics: Animals; Bicarbonates; Cells, Cultured; Extracellular Matrix; Hydrogen-Ion Concentration; Molecular Structure; Molsidomine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peroxynitrous Acid; Rats; Swine; Tyrosine | 2008 |
The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord.
Topics: Action Potentials; Animals; Axons; Cell Membrane; Dose-Response Relationship, Drug; Extracellular Fluid; Female; Guinea Pigs; Molsidomine; Nerve Degeneration; Neural Conduction; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Peroxynitrous Acid; Sodium Channels; Spinal Cord; Spinal Cord Injuries; Tyrosine | 2008 |
LDL protein nitration: implication for LDL protein unfolding.
Topics: Animals; Aorta; Apolipoprotein B-100; Cattle; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Models, Chemical; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Protein Conformation; Protein Denaturation; Protein Processing, Post-Translational; Protein Structure, Secondary; Proteins; Reproducibility of Results; Tyrosine | 2008 |
Hemin-H2O2-NO2(-) induced protein oxidation and tyrosine nitration are different from those of SIN-1: a study on glutamate dehydrogenase nitrative/oxidative modification.
Topics: Animals; Cattle; Circular Dichroism; Glutamate Dehydrogenase; Hemin; Hydrogen Peroxide; Mass Spectrometry; Molsidomine; Nitric Oxide Donors; Nitrites; Oxidation-Reduction; Reactive Nitrogen Species; Tyrosine | 2009 |
Synthesis and biological activities of neoechinulin A derivatives: new aspects of structure-activity relationships for neoechinulin A.
Topics: Animals; Antioxidants; Brain Chemistry; Cell Survival; Indicators and Reagents; Indole Alkaloids; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Molsidomine; Nitrates; PC12 Cells; Peroxynitrous Acid; Piperazines; Protective Agents; Rats; Structure-Activity Relationship; Tyrosine | 2008 |
Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo.
Topics: Amino Acid Sequence; Animals; Bronchoalveolar Lavage Fluid; Humans; Mice; Molsidomine; Nitrogen Dioxide; Peroxynitrous Acid; Protein Structure, Quaternary; Protein Structure, Tertiary; Pulmonary Surfactant-Associated Protein D; Rats; Recombinant Proteins; Tandem Mass Spectrometry; Tyrosine | 2009 |
Peroxynitrite induces gene expression in intervertebral disc cells.
Topics: Active Transport, Cell Nucleus; Adolescent; Adult; Cell Nucleus; Cells, Cultured; Female; Gene Expression; Humans; Immunohistochemistry; Interleukin-10; Interleukin-1beta; Interleukin-6; Interleukin-8; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine | 2009 |
Tempol protection of spinal cord mitochondria from peroxynitrite-induced oxidative damage.
Topics: Animals; Antioxidants; Cell Respiration; Cyclic N-Oxides; Female; Mitochondria; Molsidomine; Nitric Oxide Donors; Nitroso Compounds; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spin Labels; Spinal Cord; Tyrosine | 2009 |
Inhibition of the soluble epoxide hydrolase by tyrosine nitration.
Topics: Animals; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Mice; Mice, Inbred C57BL; Mice, Obese; Molsidomine; Mutagenesis, Site-Directed; Oxidative Stress; Peroxynitrous Acid; Tyrosine | 2009 |
The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion.
Topics: Blood Platelets; Blood Proteins; Cell Adhesion; Enzyme Inhibitors; Fibrinogen; Free Radical Scavengers; Guanylate Cyclase; Humans; Molsidomine; Nitrates; Peroxynitrous Acid; Solubility; Superoxides; Thrombin; Tyrosine | 2010 |
Protective effects of flavonoids against oxidative stress induced by simulated microgravity in SH-SY5Y cells.
Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Flavonols; Humans; Hydrogen Peroxide; Luteolin; Molecular Structure; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Oxidants; Oxidative Stress; Quercetin; Reactive Oxygen Species; Tyrosine; Weightlessness | 2010 |
Apoptosis of hepatic stellate cells mediated by specific protein nitration.
Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line; DNA Fragmentation; Hepatic Stellate Cells; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Liver Cirrhosis; Molsidomine; Nitric Oxide; Peroxynitrous Acid; Protein-Tyrosine Kinases; Rats; Signal Transduction; src-Family Kinases; Syk Kinase; Tyrosine | 2011 |
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.
Topics: Acetophenones; Allopurinol; Animals; Arrhythmias, Cardiac; Coronary Vessels; Ethidium; Male; Molsidomine; Myocardial Infarction; Myocardium; NADPH Oxidases; Nerve Growth Factor; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Sympathetic Nervous System; Tyrosine; Xanthine Oxidase | 2011 |
Detection of peroxynitrite accumulation in Arabidopsis thaliana during the hypersensitive defense response.
Topics: Aniline Compounds; Arabidopsis; Bacterial Proteins; Boron Compounds; Fluoresceins; Molsidomine; Nitric Oxide; Peroxynitrous Acid; Photometry; Plant Diseases; Plant Leaves; Protein Processing, Post-Translational; Pseudomonas syringae; Signal Transduction; Tyrosine; Uric Acid | 2011 |
Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats.
Topics: Animals; Azepines; Biomarkers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; Male; Mesenteric Arteries; Molsidomine; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phosphodiesterase 4 Inhibitors; Rats; Rats, Sprague-Dawley; Tyrosine; Vascular System Injuries | 2011 |
High glucose induced rat aorta vascular smooth muscle cell oxidative injury: involvement of protein tyrosine nitration.
Topics: Animals; Aorta; Cell Survival; Glucose; Glucose Oxidase; Glutathione; Hemin; Lipid Peroxidation; Male; Molsidomine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Primary Cell Culture; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine | 2011 |
Neuroprotective effects of Cyperus rotundus on SIN-1 induced nitric oxide generation and protein nitration: ameliorative effect against apoptosis mediated neuronal cell damage.
Topics: Apoptosis; Blotting, Western; Caspase 3; Catalase; Cell Death; Cell Line, Tumor; Cyperus; Cytoprotection; DNA Damage; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Humans; Lipid Peroxidation; Molsidomine; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rhizome; Superoxide Dismutase; Tyrosine | 2013 |
Tyrosine nitration provokes inhibition of sunflower carbonic anhydrase (β-CA) activity under high temperature stress.
Topics: Carbonic Anhydrases; Enzyme Activation; Helianthus; Models, Molecular; Molsidomine; Nitric Oxide; Protein Processing, Post-Translational; Stress, Physiological; Temperature; Tyrosine | 2013 |
Posttranslational nitro-glycative modifications of albumin in Alzheimer's disease: implications in cytotoxicity and amyloid-β peptide aggregation.
Topics: Aged; Albumins; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Female; Glycosylation; Humans; Male; Molsidomine; Neurons; Peptide Fragments; Protein Aggregates; Protein Processing, Post-Translational; tau Proteins; Trypsin; Tyrosine | 2014 |
Effect of oxidative stress on the expression of thin filament-associated proteins in gastric smooth muscle cells.
Topics: Animals; Gastrointestinal Motility; Gene Expression Regulation; Male; Microfilament Proteins; Molsidomine; Muscle, Smooth; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stomach; Tyrosine | 2014 |
Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex.
Topics: Animals; Calcium Chloride; CHO Cells; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Ileum; KATP Channels; Mice; Molsidomine; Muscle Contraction; Muscle, Smooth; Mutation; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction; Sulfides; Sulfonylurea Receptors; Transfection; Tyrosine | 2015 |
Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme.
Topics: Aniline Compounds; Anti-Inflammatory Agents; Catechin; Fluoresceins; Halogenation; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Molsidomine; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Peroxynitrous Acid; Tyrosine | 2015 |
Triosephosphate isomerase tyrosine nitration induced by heme-NaNO
Topics: Acetophenones; Anthracenes; Antioxidants; Circular Dichroism; Flavonoids; Heme; Hydrogen Peroxide; Indicators and Reagents; Kinetics; Molsidomine; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Phytochemicals; Protein Processing, Post-Translational; Protein Structure, Secondary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sodium Nitrite; Triose-Phosphate Isomerase; Tyrosine | 2017 |