linsidomine has been researched along with quinoxalines in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (24.32) | 18.2507 |
| 2000's | 23 (62.16) | 29.6817 |
| 2010's | 5 (13.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shibata, S; Tanaka, T; Watanabe, S; Yamamoto, Y | 1 |
| Cantabrana, B; Hidalgo, A; Menéndez Antolin, L; Pérez Vallina, JR; Sánchez, M | 1 |
| Ackermann, A; Fernández-Alfonso, MS; González, C; Ortega, T; Paul, M; Sánchez de Rojas, R | 1 |
| Fernández-Tomé, P; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Fiore, SA; Homer, KL; Wanstall, JC | 1 |
| Rehder, V; Van Wagenen, S | 1 |
| Alves-Do-Prado, W; Ambiel, CR; Silva, HM | 1 |
| Briski, KP | 1 |
| Chesnais, JM; Fischmeister, R; Mery, PF | 1 |
| Bae, HR; Bae, KW; Kang, EK; Lee, SA; Park, HT; Park, JK | 1 |
| Ekelund, UE; Georgakopoulos, D; Hare, JM; Harrison, RW; Isoda, T; Kass, DA; Ozaki, M; Paolocci, N; Vandegaer, K | 1 |
| Tiritilli, A | 1 |
| Prado, WA; Sousa, AM | 1 |
| Kizawa, Y; Kusama, T; Murakami, H; Ohuchi, N; Saito, K | 1 |
| De Iuri, L; Imbrogno, S; Mazza, R; Tota, B | 1 |
| Garland, CJ; Plane, F; Sampson, LJ; Smith, JJ | 1 |
| Fernández, E; Jiménez, M; Tanović, A | 1 |
| Buxton, IL; Kaiser, RA; Malmquist, NA; Tichenor, S | 1 |
| Antunes, E; Conran, N; De Nucci, G; Ferreira, HH; Kandratavicius, L; Lodo, ML; Martins, AR; Salaroli, AF | 1 |
| Graier, WF; Groschner, K; Malli, R; Schmidt, K; Thyagarajan, B | 1 |
| Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z | 1 |
| Ferreira, SH; Parada, CA; Vivancos, GG | 1 |
| Jun, CH; Lee, TS; Sohn, UD | 1 |
| Déciga-Campos, M; López-Muñoz, FJ | 1 |
| Cho, KW; Cui, X; Jin, JY; Kim, SH; Kim, SM; Kim, SZ; Lee, HS; Wen, JF | 1 |
| Brading, AF; Deka, DK | 1 |
| Correia, NC; Guarino, MP; Lautt, WW; Macedo, MP | 1 |
| Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Mura, MP; Rocchitta, G; Serra, PA | 1 |
| Andersen, CU; Mulvany, MJ; Simonsen, U | 1 |
| Elmedal Laursen, B; Mulvany, MJ; Simonsen, U | 1 |
| Faggio, C; Pidalà, P; Trischitta, F | 1 |
| Aguiar, DC; Braga, AA; Guimarães, FS | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Sarac, B; Sencan, M; Turan, M | 1 |
| Arner, A; de Sá, VP; Ekblad, E; Harnek, J; Stenram, U; Zoucas, E | 1 |
| Lu, L; Shimizu, T; Tanaka, K; Yokotani, K | 1 |
| Badejo, AM; Bhartiya, M; Bueno, FR; Casey, DB; Kadowitz, PJ; Murthy, SN; Nossaman, BD; Pankey, EA; Uppu, RM | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Gursoy, S; Ozdemir, E | 1 |
37 other study(ies) available for linsidomine and quinoxalines
| Article | Year |
|---|---|
NG-nitro-L-arginine protects against hypoxia/hypoglycemia-induced decrease in CA1 presynaptic spikes in rat hippocampal slices.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electrophysiology; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Molsidomine; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Receptors, Presynaptic; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Nitric oxide and cyclic nucleotides participate in the relaxation of diclofenac on rat uterine smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Enzyme Inhibitors; Female; GTP-Binding Proteins; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Nucleotides, Cyclic; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Rats, Wistar; Sensitivity and Specificity; Sulfonamides; Uterine Contraction; Uterus; Vanadates; Vasodilator Agents; Virulence Factors, Bordetella | 1998 |
Modulation of angiotensin-converting enzyme by nitric oxide.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Carotid Arteries; Diethylamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Oligopeptides; Oxadiazoles; Peptidyl-Dipeptidase A; Quinoxalines; Rabbits; Rats; Rats, Sprague-Dawley | 1998 |
Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP.
Topics: Animals; Cell Death; Cyclic GMP; Drug Synergism; Enzyme Inhibitors; Hydrogen Peroxide; Molsidomine; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilator Agents | 1998 |
Inhibition by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) of responses to nitric oxide-donors in rat pulmonary artery: influence of the mechanism of nitric oxide generation.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitrogen Oxides; Oxadiazoles; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; Spermine; Vasodilation | 1999 |
Regulation of neuronal growth cone filopodia by nitric oxide.
Topics: Animals; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Cones; Guanylate Cyclase; Hydrazines; Molsidomine; Mutagens; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Pseudopodia; Quinoxalines; Snails; Sulfhydryl Reagents | 1999 |
The neuromuscular transmission fade (Wedensky inhibition) induced by L-arginine in neuromuscular preparations from rats.
Topics: Animals; Arginine; Diaphragm; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Molsidomine; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Nitroarginine; Oxadiazoles; Phrenic Nerve; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Pharmacological manipulation of central nitric oxide/guanylate cyclase activity alters Fos expression by rat hypothalamic vasopressinergic neurons during acute glucose deprivation.
Topics: Animals; Deoxyglucose; Enzyme Inhibitors; Glucose; Guanylate Cyclase; Hypothalamus; Immunoenzyme Techniques; Male; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1; Vasopressins | 1999 |
Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart.
Topics: Aminoquinolines; Animals; Atrial Function; Catalase; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Heart Atria; Heart Ventricles; Hydroxyl Radical; Molsidomine; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Donors; Oxadiazoles; Oxidants; Quinoxalines; Rana esculenta; Sodium; Sodium-Calcium Exchanger; Ventricular Function | 1999 |
Calmodulin-dependent activation of p38 and p42/44 mitogen-activated protein kinases contributes to c-fos expression by calcium in PC12 cells: modulation by nitric oxide.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, fos; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Potassium Chloride; Proto-Oncogene Proteins c-fos; Pyridines; Quinoxalines; Rats; Sulfonamides | 2000 |
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
Topics: Animals; Cyclic GMP; Diethylamines; Drug Combinations; Enzyme Inhibitors; Glutathione; In Vitro Techniques; Male; Molsidomine; Myocardial Contraction; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nucleotides, Cyclic; Oxadiazoles; Oxidation-Reduction; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Guanylate cyclase and not ATP-dependent K(+) channels seems temperature-dependent in smooth muscle relaxation of human umbilical arteries.
Topics: Adenosine Triphosphate; Arginine; Cromakalim; Dose-Response Relationship, Drug; Female; Glyburide; Guanylate Cyclase; Humans; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; Nicorandil; Nitroarginine; Oxadiazoles; Potassium Channels; Pregnancy; Quinoxalines; Serotonin; Temperature; Umbilical Arteries; Vasodilation; Vasodilator Agents | 2000 |
The dual effect of a nitric oxide donor in nociception.
Topics: Animals; Chronic Disease; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemoglobins; Injections, Spinal; Ligation; Male; Molsidomine; Nerve Compression Syndromes; Neuralgia; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Sciatic Nerve | 2001 |
Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells.
Topics: Animals; Bronchi; Cell Division; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Male; Molsidomine; Muscle, Smooth; Nitric Oxide; Oxadiazoles; Peptides, Cyclic; Quinoxalines | 2001 |
Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Anguilla; Animals; Arginine; Atropine; Detergents; Enzyme Inhibitors; Female; Free Radical Scavengers; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Molsidomine; Muscarinic Antagonists; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Octoxynol; omega-N-Methylarginine; Ornithine; Oxadiazoles; Parasympatholytics; Pirenzepine; Quinoxalines; Superoxide Dismutase | 2001 |
Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Peptides; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Vasodilation | 2001 |
Actions of NO donors and endogenous nitrergic transmitter on the longitudinal muscle of rat ileum in vitro: mechanisms involved.
Topics: Animals; Apamin; Atropine; Calcium Channels; Charybdotoxin; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ileum; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetrodotoxin | 2001 |
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP.
Topics: Charybdotoxin; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Labor, Obstetric; Molsidomine; Muscle Relaxation; Muscle, Smooth; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Oxytocin; Penicillamine; Peptides; Pregnancy; Quinoxalines; S-Nitrosothiols; Scorpion Venoms; Time Factors; Uterus | 2001 |
Expression of nitric oxide synthases and in vitro migration of eosinophils from allergic rhinitis subjects.
Topics: Cell Movement; Chemokine CCL11; Chemokines, CC; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Guanylate Cyclase; Humans; Isoenzymes; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; Rhinitis, Allergic, Perennial; S-Nitroso-N-Acetylpenicillamine; Solubility | 2002 |
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
Topics: Barium; Calcium; Cell Line; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Oxygen Consumption; Peroxynitrous Acid; Quinoxalines; Thapsigargin; Time Factors | 2002 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues.
Topics: Animals; Arginine; Bucladesine; Cyclic GMP; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Subcutaneous; Male; Molsidomine; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Subcutaneous Tissue; Time Factors | 2003 |
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagogastric Junction; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Signal Transduction; Vasoactive Intestinal Peptide | 2003 |
Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoenzymes; Lactones; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Sulfones; Uric Acid | 2003 |
High and low gain switches for regulation of cAMP efflux concentration: distinct roles for particulate GC- and soluble GC-cGMP-PDE3 signaling in rabbit atria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Animals; Atrial Natriuretic Factor; Biological Transport; Cardiac Pacing, Artificial; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Enzyme Inhibitors; Guanylate Cyclase; Heart Atria; Milrinone; Molsidomine; Myocardial Contraction; Myocytes, Cardiac; Natriuretic Peptide, C-Type; Nitric Oxide Donors; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazoles; Pyridines; Quinoxalines; Rabbits; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Soluble Guanylyl Cyclase; Stroke Volume | 2004 |
Nitric oxide activates glibenclamide-sensitive K+ channels in urinary bladder myocytes through a c-GMP-dependent mechanism.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glyburide; Guinea Pigs; Indoles; Ion Channel Gating; Male; Membrane Potentials; Molsidomine; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Potassium Channels; Quinoxalines; Signal Transduction; Urinary Bladder | 2004 |
Insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver.
Topics: Acetylcholine; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Injections, Intravenous; Insulin Resistance; Liver; Male; Molsidomine; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Portal Vein; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2004 |
Signalling pathways in the nitric oxide donor-induced dopamine release in the striatum of freely moving rats: evidence that exogenous nitric oxide promotes Ca2+ entry through store-operated channels.
Topics: Animals; Boron Compounds; Calcium; Chelating Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Egtazic Acid; Electrochemistry; Functional Laterality; Male; Microdialysis; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Quinoxalines; Rats; Rats, Wistar; S-Nitrosoglutathione; Signal Transduction; Wakefulness | 2004 |
Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats.
Topics: Acetylcholine; Actins; Animals; Atrial Natriuretic Factor; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Guanylate Cyclase; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Lung; Male; Molsidomine; Muscle, Smooth; Oxadiazoles; Piperazines; Pulmonary Artery; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Systole; Vasodilation; Vasodilator Agents | 2005 |
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor.
Topics: Animals; Bronchi; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Ouabain; Oxadiazoles; Peptides; Potassium; Quinoxalines; S-Nitrosoglutathione; Serotonin; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Triazoles | 2006 |
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Anguilla; Animals; Arginine; Bicarbonates; Chlorides; Cyclic GMP; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Potentials; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Permeability; Quinoxalines; Time Factors | 2007 |
NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase.
Topics: Animals; Catheterization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escape Reaction; Guanylate Cyclase; Male; Microinjections; Molsidomine; Motor Activity; Multivariate Analysis; Nitric Oxide Donors; Oxadiazoles; Periaqueductal Gray; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Time Factors; Triazenes | 2009 |
Investigation of relaxant effects of new agents affecting nitric oxide/cyclic guanosine monophosphate pathway on sheep oddi sphincter.
Topics: Animals; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Sheep; Sphincter of Oddi; Triazenes | 2010 |
Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway.
Topics: Actins; Analysis of Variance; Angioplasty, Balloon, Coronary; Animals; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Guanylate Cyclase; Hyperplasia; Intermediate Filaments; Molsidomine; Myosins; NAD(P)H Dehydrogenase (Quinone); NADP; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Signal Transduction; Sus scrofa; Time Factors; Tunica Intima | 2011 |
Possible involvement of S-nitrosylation of brain cyclooxygenase-1 in bombesin-induced central activation of adrenomedullary outflow in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenal Medulla; Animals; Benzoates; Bombesin; Brain; Catecholamines; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Ethylmaleimide; Imidazoles; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide Donors; Oxadiazoles; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; S-Nitrosothiols; Sulfhydryl Reagents | 2012 |
Peroxynitrite has potent pulmonary vasodilator activity in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Male; Molsidomine; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Peroxynitrous Acid; Pulmonary Artery; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2012 |
Soluble guanylyl cyclase activators increase the expression of tolerance to morphine analgesic effect.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Male; Molsidomine; Morphine; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Photosensitizing Agents; Protoporphyrins; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Restriction Mapping; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase | 2014 |