Compounds > linsidomine
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linsidomine and penicillamine

linsidomine has been researched along with penicillamine in 135 studies

Research

Studies (135)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's94 (69.63)18.2507
2000's40 (29.63)29.6817
2010's1 (0.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gryglewski, RJ; Salvemini, D; Taylor, GW; Vane, JR; Zembowicz, A1
Darley-Usmar, VM; Hogg, N; Moncada, S; O'Leary, VJ; Wilson, MT1
Garthwaite, J; Southam, E2
Batchelor, AM; East, SJ; Garthwaite, J1
Akarid, K; Desforges, B; Gougerot-Pocidalo, MA; Sinet, M1
Choi, DW; Csernansky, CA; Hewett, SJ1
Shibata, S; Tanaka, T; Watanabe, S; Yamamoto, Y1
Furukawa, T; Kohno, H; Taketani, S; Tokunaga, R1
Andrew, PJ; Harant, H; Lindley, IJ1
Nagy, E; Neumannova, V; Ponka, P; Richardson, DR1
Beauvais, F; Dubertret, L; Michel, L1
deGroot, H; Hensel, M; Ioannidis, I; Kox, WJ; Volk, T1
Bialecki, RA; Stinson-Fisher, C1
Meffert, MK; Premack, BA; Schulman, H1
Cunningham, JM; Delaney, CA; Green, IC; Mabley, JG1
Beckman, J; Crow, JP; Haddad, IY; Hu, P; Matalon, S; Ye, Y1
Ceppi, ED; Horton, RA; Knowles, RG; Titheradge, MA1
de Groot, H; Ioannidis, I1
Darley-Usmar, VM; Hogg, N; Moncada, S; Wilson, MT1
Brenner, HH; Etzkorn, K; Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Noack, EA; Rodriguez, ML1
Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E; Vapaatalo, H; Vuorinen, P1
Galluser, M; Raul, F; Schleiffer, R1
Chaudhuri, G; Chopra, M; Gryglewski, R; Ignarro, LJ; Radziszewski, W; Zembowicz, A1
Brien, JF; Jimmo, SL; Marks, GS; McLaughlin, BE; Nakatsu, K; Poklewska-Koziell, M1
Dikshit, M; Shukla, A; Srimal, RC1
Lapetina, EG; Reep, BR1
Currie, MG; Mollace, V; Salvemini, D1
Brutsaert, DL; Mohan, P; Paulus, WJ; Sys, SU1
Constantine-Paton, M; Rentería, RC1
Behar-Cohen, FF; Courtois, Y; D'Hermies, F; Goureau, O1
Kawanishi, M1
Palluy, O; Rigaud, M1
Irifune, M; Kamata, Y; Nishikawa, T; Sato, T1
Barefield, E; Crow, J; Gadilhe, T; Haddad, IY; Matalon, S; Zhu, S1
Foresti, R; Intaglietta, M; Motterlini, R; Winslow, RM1
Garcia-Dorado, D; Jakob, G; Piper, HM; Ruiz-Meana, M; Schlüter, KD1
Fandrey, J; Hoffmann, G; Schobersberger, W1
Pehl, U; Schmid, HA1
Ebihara, Y; Karmazyn, M1
Grisham, MB; Milligan, SA; Owens, MW1
Kapás, L; Krueger, JM1
Sontheimer, H; Ye, ZC1
Adler, KB; Akley, NJ; Fischer, BM; Li, C; Rochelle, LG; Wright, DT1
Damoulis, PD; Hauschka, PV1
Christodoulides, N; Durante, W; Kroll, MH; Peyton, KJ; Schafer, AI1
Bauer, H; Frölich, JC; Jung, T; Neumann, C; Stichtenoth, DO; Tsikas, D1
Iadecola, C; Yang, G1
Brady, T; D'Ambrosio, SM; Oberyszyn, TM; Robertson, FM; Ross, MS1
Fandrey, J; Kiprianova, I; Schwab, S; Spranger, M1
Dietl, P; Friedrich, F; Hoffmann, G; Schobersberger, W; Völkl, H1
Boscá, L; Dallaporta, B; Hirsch, T; Hortelano, S; Kroemer, G; Marzo, I; Susin, SA; Zamzami, N1
Behrendt, J; Beste, O; Dittrich, K; Dötsch, J; Hänze, J; Rascher, W; Weber, WM1
Ade, P; Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E1
Brorson, JR; Zhang, H1
D'Souza, SW; Lees, RD; Slater, P1
Janssen, YM; Matalon, S; Mossman, BT1
Bhatnagar, A; Chandra, A; Petrash, JM; Srivastava, S; Srivastava, SK1
Billiar, TR; Kim, YM; Li, J; Talanian, RV1
Cullen, VC; Eustace, NP; Keenan, AK1
Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Robak, J1
Nishio, E; Watanabe, Y1
Demontis, MP; Emanueli, C; Madeddu, P; Varoni, MV; Volpe, AR1
Chang, ES; Graubard, K; Scholz, NL; Truman, JW1
Denenberg, AG; Kennedy, M; Salzman, AL; Szabó, C1
Gauer, S; Pröls, F; Schoecklmann, HO; Sterzel, RB; Yao, J1
Hagino, Y; Matsui, S; Nomura, H; Nomura, T; Ohtsuki, M; Sumi-Ichinose, C1
Elmedal, B; Hernández, M; Mulvany, MJ; Simonsen, U1
Akita, H; Hirata, K; Kawashima, S; Rikitake, Y; Yokoyama, M1
Cohen, RA; Garland, CJ; Jeremy, JY; Plane, F; Wiley, KE1
Lee, EH; Tsai, MJ1
Holm, P; Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E1
Ahmed, U; Conant, K; Major, EO; Schwartz, JP1
Bernassola, F; Catani, MV; Melino, G; Rossi, A1
Bocca, AL; Campanelli, AP; Cunha, FQ; Figueiredo, F; Furlanetto, AB; Hayashi, EE; Pinheiro, AG1
Lähteenmäki, T; Sievi, E; Vapaatalo, H1
Aguirre, DE; Fink, MP; Menconi, MJ; Smith, M; Unno, N1
Keilhoff, G; Reiser, M; Schild, L; Wolf, G1
Aizenman, E; Potthoff, WK1
Buus, NH; Mulvany, MJ; Simonsen, U; Wadsworth, RM1
Hirata, K; Kanazawa, H; Okamoto, T; Shiraishi, S; Yoshikawa, J1
Hatori, M; Kamijo, R; Nagumo, M; Sumitani, K; Takizawa, K; Toyoshima, T1
Archer, DC; Blantz, RC; Ishizuka, S; Kelly, CJ; Satriano, J1
Roberts, LJ; van der Veen, RC1
Choi, JJ; Kim, WK; Ko, KH; Seo, DO1
Chesnais, JM; Fischmeister, R; Méry, PF1
Immenschuh, S; Iwahara, S; Ramadori, G; Stritzke, J1
Kim, HS; Kim, SH; Son, YR1
Lenzen, S; Lortz, S; Munday, R; Tiedge, M1
Chénais, B; Jeannesson, P; Molle, I1
Iwase, M; Nagumo, M; Ohashi, M1
Deeb, RS; Hajjar, DP; Upmacis, RK1
Campagnolo, C; Claveau, D; Li, C; Ouellet, M; Percival, MD1
Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E1
Hirata, K; Kanazawa, H; Yoshikawa, J1
Cox, G; Janssen, LJ; Keshavjee, S; Lu-Chao, H; Premji, M1
Ju, C; Kim, HC; Kim, WK; Ko, KH; Oh, YK; Ryu, JR; Shin, CY; Yoon, KN1
Abate, A; Dennery, PA; Polte, T; Schröder, H1
Benhamou, PY; Kerr-Conte, J; Lemarchand, P; Moriscot, C; Pattou, F; Richard, MJ1
Komarov, AM; Mak, IT; Weglicki, WB1
Chen, JW; Eatock, RA1
Nieland, LJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; Steinbusch, HW; Terwel, D1
Cai, L; Ingram, AJ; James, L; Ly, H; Scholey, JW; Thai, K1
Muriel, P; Sandoval, G1
Buckley, BJ; Whorton, AR1
Andersson, RG; Glindell, M; Jacobsson-Strier, M; Nyhlén, K; Persson, K; Whiss, PA1
Marthan, R; Pauvert, O; Savineau, J1
Jensen, MS; Nyborg, NC; Thomsen, ES1
Bernardet, N; Dambrine, G; Djeraba, A; Quéré, P1
Campos-Pérez, JJ; Ellis, AE; Secombes, CJ1
Brady, T; D'Ambrosio, SM; Gibson-D'Ambrosio, RE; Oberyszyn, AS; Robertson, FM1
Flores, A; Soto, E; Vega, R1
Decking, UK; Schrader, J; Stumpe, T1
Ascenzi, P; Colasanti, M; Gradoni, L; Mattu, M; Salvati, L; Scalone, A; Venturini, G1
Choi, JW; Kim, H; Kim, W; Ko, KH; Ryu, JH; Ryu, JR; Shin, CY1
Buxton, IL; Kaiser, RA; Malmquist, NA; Tichenor, S1
Cooke, JP; Dulak, J; Funovics, P; Guevara, I; Huk, I; Jozkowicz, A; Pachinger, O; Weidinger, F1
Hewett, JA; Hewett, SJ; Uliasz, TF; Vidwans, AS1
Assreuy, J; Sampaio de Freitas, M; Santos-Silva, MC1
Droogmans, G; Nilius, B; Suh, SH; Watanabe, H1
Esumi, H; Kimura, H; Kurashima, Y; Ogura, T; Weisz, A1
Laude, K; Richard, V; Thuillez, C1
Assreuy, J; Costa, RS1
Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z1
Beltrán, A; González, D; Herrera, B; Otero, K; Quintero, G; Rojas, A1
Antunes, E; De Nucci, G; Marcondes, S; Moreira, J; Thomazzi, SM1
Kim, KH; Kim, SK; Kim, SM; Kwon, SR; Lee, EH; Nam, YK1
Adapala, NS; Chan, MM; Fong, D1
Abiru, S; Eguchi, K; Ishibashi, H; Komori, A; Maeda, Y; Migita, K; Nakamura, M; Takii, Y; Yatsuhashi, H; Yokoyama, T1
Bar-Shai, M; Reznick, AZ1
Dirnagl, U; Dreier, JP; Lindauer, U; Scheckenbach, KE1
Bar-Shai, M; Hasnis, E; Reznick, AZ; Wiener-Megnazi, Z1
Hall, ED; Singh, IN; Sullivan, PG1
Greenberg, DA; Jin, K; Khan, AA; Mao, XO; Xie, L1
Badejo, AM; Bhartiya, M; Bueno, FR; Casey, DB; Kadowitz, PJ; Murthy, SN; Nossaman, BD; Pankey, EA; Uppu, RM1

Other Studies

135 other study(ies) available for linsidomine and penicillamine

ArticleYear
Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Animals; Aorta; Cyclic GMP; Drug Interactions; In Vitro Techniques; Methylene Blue; Molsidomine; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Platelet Aggregation; Pyocyanine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Vasodilator Agents

1992
The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein.
    Free radical research communications, 1992, Volume: 17, Issue:1

    Topics: Antioxidants; Catalase; Humans; Lipid Peroxidation; Lipoproteins, LDL; Molecular Structure; Molsidomine; Nitric Oxide; Nitroprusside; Oxygen Consumption; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Time Factors

1992
Comparative effects of some nitric oxide donors on cyclic GMP levels in rat cerebellar slices.
    Neuroscience letters, 1991, Sep-02, Volume: 130, Issue:1

    Topics: Animals; Cerebellum; Cyclic GMP; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1991
Intercellular action of nitric oxide in adult rat cerebellar slices.
    Neuroreport, 1991, Volume: 2, Issue:11

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine

1991
Selective blockade of N-methyl-D-aspartate receptor function by the nitric oxide donor, nitroprusside.
    European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2

    Topics: Action Potentials; Animals; Cerebellum; Glutamates; Glutamic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical; Synapses

1991
Inhibitory effect of nitric oxide on the replication of a murine retrovirus in vitro and in vivo.
    Journal of virology, 1995, Volume: 69, Issue:11

    Topics: Animals; Antiviral Agents; Arginine; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Friend murine leukemia virus; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred DBA; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Virus Replication

1995
Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS.
    Neuron, 1994, Volume: 13, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Astrocytes; Cell Death; Cells, Cultured; Drug Synergism; Enzyme Induction; In Vitro Techniques; Interferon-gamma; Interleukin-1; Kainic Acid; Mice; Molsidomine; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; S-Nitroso-N-Acetylpenicillamine

1994
NG-nitro-L-arginine protects against hypoxia/hypoglycemia-induced decrease in CA1 presynaptic spikes in rat hippocampal slices.
    European journal of pharmacology, 1995, Feb-06, Volume: 273, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electrophysiology; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Molsidomine; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Receptors, Presynaptic; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1995
Nitric oxide-mediated inactivation of mammalian ferrochelatase in vivo and in vitro: possible involvement of the iron-sulphur cluster of the enzyme.
    The Biochemical journal, 1995, Sep-01, Volume: 310 ( Pt 2)

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Ferrochelatase; Humans; Immunoblotting; Interferon-gamma; Iron-Sulfur Proteins; Lipopolysaccharides; Macrophages; Mammals; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1995
Nitric oxide regulates IL-8 expression in melanoma cells at the transcriptional level.
    Biochemical and biophysical research communications, 1995, Sep-25, Volume: 214, Issue:3

    Topics: Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; DNA Primers; DNA-Binding Proteins; Gene Expression; Glutathione; Humans; Interleukin-8; Melanoma; Molecular Sequence Data; Molsidomine; Mutagenesis, Site-Directed; NF-kappa B; Nitric Oxide; Nitroso Compounds; Nuclear Proteins; Penicillamine; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Promoter Regions, Genetic; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Vasodilator Agents

1995
The effect of redox-related species of nitrogen monoxide on transferrin and iron uptake and cellular proliferation of erythroleukemia (K562) cells.
    Blood, 1995, Oct-15, Volume: 86, Issue:8

    Topics: Antioxidants; Biological Transport; Cell Division; Gene Expression Regulation, Leukemic; Humans; Iron; Iron-Regulatory Proteins; Leukemia, Erythroblastic, Acute; Macromolecular Substances; Models, Biological; Molsidomine; Neoplasm Proteins; Nitric Oxide; Nitroprusside; Oxidation-Reduction; Penicillamine; Protein Binding; Protein Processing, Post-Translational; Receptors, Transferrin; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; RNA, Neoplasm; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Transferrin; Tumor Cells, Cultured; Up-Regulation

1995
Exogenous nitric oxide elicits chemotaxis of neutrophils in vitro.
    Journal of cellular physiology, 1995, Volume: 165, Issue:3

    Topics: Aminoquinolines; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cysteine; Enzyme Inhibitors; Guanylate Cyclase; Humans; Molsidomine; Neutrophils; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols

1995
Endothelial damage induced by nitric oxide: synergism with reactive oxygen species.
    Biochemical and biophysical research communications, 1995, Aug-04, Volume: 213, Issue:1

    Topics: Analysis of Variance; Animals; Antimycin A; Catalase; Cells, Cultured; Endothelium; Kinetics; Liver; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Potassium Cyanide; Rats; Reactive Oxygen Species; Rotenone; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vasodilator Agents

1995
KCa channel antagonists reduce NO donor-mediated relaxation of vascular and tracheal smooth muscle.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 1

    Topics: Animals; Calcium; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Trachea

1995
Nitric oxide stimulates Ca(2+)-independent synaptic vesicle release.
    Neuron, 1994, Volume: 12, Issue:6

    Topics: Animals; Calcium; Fluorescent Dyes; Glutamates; Glutamic Acid; Hippocampus; Indoles; Kinetics; Male; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Potassium Chloride; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Spectrometry, Fluorescence; Synaptic Vesicles; Vasodilator Agents

1994
The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting cell lines HIT-T15 and RINm5F.
    Molecular and cellular endocrinology, 1994, Volume: 102, Issue:1-2

    Topics: Animals; Cell Line; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Glutathione; Hydroxylamine; Hydroxylamines; Insulin; Insulin Secretion; Islets of Langerhans; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

1994
Concurrent generation of nitric oxide and superoxide damages surfactant protein A.
    The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 1

    Topics: Humans; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Penicillamine; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Reactive Oxygen Species; Rhodamines; S-Nitroso-N-Acetylpenicillamine; Superoxides; Time Factors

1994
Inhibition of hepatic gluconeogenesis by nitric oxide: a comparison with endotoxic shock.
    The Biochemical journal, 1994, May-01, Volume: 299 ( Pt 3)

    Topics: Animals; Dihydroxyacetone; Endotoxins; Fructose; Gluconeogenesis; Glycerol; Lactates; Liver; Male; Molsidomine; Nitric Oxide; Nitrites; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Shock, Septic

1994
Cytotoxicity of nitric oxide in Fu5 rat hepatoma cells: evidence for co-operative action with hydrogen peroxide.
    The Biochemical journal, 1993, Dec-01, Volume: 296 ( Pt 2)

    Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Line; Cell Survival; Glucose Oxidase; Hydrogen Peroxide; Kinetics; Liver Neoplasms; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Tumor Cells, Cultured; Vasodilator Agents; Xanthine Oxidase

1993
The oxidation of alpha-tocopherol in human low-density lipoprotein by the simultaneous generation of superoxide and nitric oxide.
    FEBS letters, 1993, Jul-12, Volume: 326, Issue:1-3

    Topics: Acetaldehyde; Catalase; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Lipoproteins, LDL; Molsidomine; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Thiobarbiturates; Vitamin E; Xanthine Oxidase

1993
Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide.
    Biochimica et biophysica acta, 1993, Sep-08, Volume: 1182, Issue:2

    Topics: Animals; Cells, Cultured; Female; Islets of Langerhans; Male; Mice; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Inbred Lew; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Superoxides; Trypan Blue; Tumor Cells, Cultured

1993
Inhibition by nitric oxide-donors of human polymorphonuclear leucocyte functions.
    British journal of pharmacology, 1993, Volume: 109, Issue:3

    Topics: Cell Degranulation; Chemotaxis, Leukocyte; Cyclic AMP; Cyclic GMP; Glucuronidase; Humans; In Vitro Techniques; Leukotriene B4; Luminescent Measurements; Molsidomine; Neutrophils; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxides; Triazoles

1993
Intestinal absorption of calcium in vivo is dependent on endogenous nitric oxide.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:3

    Topics: Animals; Arginine; Calcium; Female; Intestinal Absorption; Intestine, Small; Male; Mesenteric Veins; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Penicillamine; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1995
Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins.
    International journal of cardiology, 1995, Volume: 51, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Blood Platelets; Cells, Cultured; Culture Media; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; Humans; Ion Transport; Molsidomine; Nitric Oxide; Ouabain; Penicillamine; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Probenecid; Prostaglandin D2; Prostaglandins; Prostaglandins A; Purinones; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Time Factors; Triazoles

1995
Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:11

    Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Luminescent Measurements; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vasodilation; Vasodilator Agents

1995
Nitric oxide-dependent blood-brain barrier permeability alteration in the rat brain.
    Experientia, 1996, Feb-15, Volume: 52, Issue:2

    Topics: Animals; Arginine; Atropine; Blood Pressure; Blood-Brain Barrier; Heart Rate; Kinetics; Microcirculation; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Permeability; Rats; Rats, Sprague-Dawley; Reference Values; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1996
Nitric oxide stimulates the phosphorylation of rap1b in human platelets and acts synergistically with iloprost.
    Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1

    Topics: Blood Platelets; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Humans; Iloprost; Kinetics; Molsidomine; Nitric Oxide; Penicillamine; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; rap GTP-Binding Proteins; S-Nitroso-N-Acetylpenicillamine

1996
Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators.
    The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Aorta; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Hemoglobins; Humans; Kinetics; Male; Methylene Blue; Models, Cardiovascular; Molsidomine; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilation; Vasodilator Agents; Verapamil

1996
Myocardial contractile response to nitric oxide and cGMP.
    Circulation, 1996, Mar-15, Volume: 93, Issue:6

    Topics: Animals; Cats; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Molsidomine; Myocardial Contraction; Nitric Oxide; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine

1996
Exogenous nitric oxide causes collapse of retinal ganglion cell axonal growth cones in vitro.
    Journal of neurobiology, 1996, Volume: 29, Issue:4

    Topics: Animals; Axons; Cells, Cultured; Cysteine; Free Radical Scavengers; Mercaptoethanol; Molsidomine; Neurites; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Penicillamine; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Sulfhydryl Reagents; Time Factors; Vasodilator Agents; Xenopus laevis

1996
Decreased intraocular pressure induced by nitric oxide donors is correlated to nitrite production in the rabbit eye.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:8

    Topics: Acetonitriles; Animals; Aqueous Humor; Eye; Eye Proteins; Female; Injections; Intraocular Pressure; Molsidomine; Morpholines; Nitric Oxide; Nitrites; Ocular Hypotension; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents; Vitreous Body

1996
Nitric oxide inhibits Epstein-Barr virus DNA replication and activation of latent EBV.
    Intervirology, 1995, Volume: 38, Issue:3-4

    Topics: Blotting, Northern; Blotting, Southern; DNA Replication; Herpesvirus 4, Human; Molsidomine; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Viral Proteins; Virus Latency; Virus Replication

1995
Nitric oxide induces cultured cortical neuron apoptosis.
    Neuroscience letters, 1996, Apr-12, Volume: 208, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; DNA; Electrophoresis, Agar Gel; Glutathione; Molsidomine; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

1996
Inhibition of purified (Na+,K+)-ATPase activity from porcine cerebral cortex by NO generating drugs.
    Brain research, 1995, Dec-15, Volume: 704, Issue:1

    Topics: Animals; Cerebral Cortex; Dithiothreitol; Enzyme Inhibitors; Molsidomine; Nitric Oxide; Nitro Compounds; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Reagents; Superoxide Dismutase; Swine

1995
Inhibition of alveolar type II cell ATP and surfactant synthesis by nitric oxide.
    The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 1

    Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Cells, Cultured; Molsidomine; Nitric Oxide; Nitrogen Oxides; Penicillamine; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Spermine

1996
NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Bilirubin; Cell Line; Cell Survival; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Heme Oxygenase (Decyclizing); Hydrogen Peroxide; Male; Molsidomine; Nitric Oxide; Nitrites; Nitroprusside; Oxidative Stress; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine

1996
Protection of reoxygenated cardiomyocytes against osmotic fragility by nitric oxide donors.
    The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 2

    Topics: Animals; Antioxidants; Diacetyl; Enzyme Activation; Guanylate Cyclase; Hypoxia; Male; Molsidomine; Myocardium; Nitric Oxide; Nitroprusside; Osmotic Fragility; Oxygen; Penicillamine; Phenylenediamines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine

1996
Nitric oxide donors suppress erythropoietin production in vitro.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:6

    Topics: Carcinoma, Hepatocellular; Cyclic GMP; Cytokines; Erythropoietin; Humans; Hydrogen Peroxide; Liver Neoplasms; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured

1996
Regional specific effects of nitric oxide donors and cGMP on the electrical activity of neurons in the rat spinal cord.
    Journal of chemical neuroanatomy, 1996, Volume: 10, Issue:3-4

    Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Histocytochemistry; Male; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Organ Culture Techniques; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Spinal Cord; Vasodilator Agents

1996
Inhibition of beta- but not alpha 1-mediated adrenergic responses in isolated hearts and cardiomyocytes by nitric oxide and 8-bromo cyclic GMP.
    Cardiovascular research, 1996, Volume: 32, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Cell Size; Cells, Cultured; Cyclic GMP; Isoproterenol; Male; Molsidomine; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Perfusion; Phenylephrine; Propranolol; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical; Vasodilator Agents

1996
Inhibition of pleural mesothelial cell collagen synthesis by nitric oxide.
    Free radical biology & medicine, 1996, Volume: 21, Issue:5

    Topics: Animals; Cell Line; Collagen; Cytokines; Epithelial Cells; Epithelium; Free Radicals; Inflammation Mediators; Lipopolysaccharides; Molsidomine; Nitric Oxide; Penicillamine; Pleura; Rats; S-Nitroso-N-Acetylpenicillamine

1996
Nitric oxide donors SIN-1 and SNAP promote nonrapid-eye-movement sleep in rats.
    Brain research bulletin, 1996, Volume: 41, Issue:5

    Topics: Animals; Body Temperature; Electroencephalography; Enzyme Inhibitors; Male; Molsidomine; Motor Activity; Nitric Oxide; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sleep; Sodium-Potassium-Exchanging ATPase

1996
Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide.
    Neuroreport, 1996, Sep-02, Volume: 7, Issue:13

    Topics: Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Cytokines; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Humans; Interferon-gamma; Interleukin-1; Kinetics; Molsidomine; Neuroglia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penicillamine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha

1996
Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: Animals; Cell Transformation, Viral; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium; Guinea Pigs; Humans; Hydrogen Peroxide; Molsidomine; Mucins; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Peroxides; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxides; tert-Butylhydroperoxide; Trachea; Type C Phospholipases; Xanthine Oxidase

1996
Nitric oxide acts in conjunction with proinflammatory cytokines to promote cell death in osteoblasts.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:3

    Topics: Animals; Bone Remodeling; Cell Death; Cell Line; Coculture Techniques; Glutathione; Hormones; Humans; Interferon-gamma; Interleukin-1; Mice; Molsidomine; Nitric Oxide; Nitroso Compounds; Osteoblasts; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Tumor Necrosis Factor-alpha

1997
Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells.
    Circulation research, 1997, Volume: 80, Issue:4

    Topics: Animals; Carbon Monoxide; Cells, Cultured; Cyclic GMP; Cycloheximide; Cytokines; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic

1997
Nitric oxide inhibits the secretion of T-helper 1- and T-helper 2-associated cytokines in activated human T cells.
    Immunology, 1997, Volume: 90, Issue:2

    Topics: CD3 Complex; Cell Culture Techniques; Cell Division; Cytokines; Humans; Lymphocyte Activation; Molsidomine; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Th1 Cells; Th2 Cells

1997
Obligatory role of NO in glutamate-dependent hyperemia evoked from cerebellar parallel fibers.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebellum; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Glutamic Acid; Hyperemia; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Papaverine; Partial Pressure; Penicillamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Vasodilation

1997
Sensitivity of human hepatocytes in culture to reactive nitrogen intermediates.
    Biochemical and biophysical research communications, 1997, Apr-17, Volume: 233, Issue:2

    Topics: Cells, Cultured; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Molsidomine; Nitrites; Nitrogen; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Tyrosine

1997
Suppression of the oxidative burst in murine microglia by nitric oxide.
    Neuroscience letters, 1997, Apr-25, Volume: 226, Issue:2

    Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Interferon-gamma; Interleukin-1; Kinetics; Luminescent Measurements; Mice; Microglia; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Respiratory Burst; S-Nitroso-N-Acetylpenicillamine; Superoxides

1997
Nitric oxide donors inhibit spontaneous depolarizations by L-type Ca2+ currents in alveolar epithelial cells.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Aminoquinolines; Animals; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cyclic GMP; Enzyme Inhibitors; Epithelium; Guanylate Cyclase; Kinetics; Membrane Potentials; Microelectrodes; Molsidomine; Nitroprusside; Penicillamine; Pulmonary Alveoli; Rats; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Strontium; Time Factors

1997
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.
    FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3

    Topics: Animals; Apoptosis; Cells, Cultured; Glutathione; Intracellular Membranes; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Permeability; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Thymus Gland

1997
Suppression of neuropeptide Y1 receptor function in SK-N-MC cells by nitric oxide.
    The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 1

    Topics: Blotting, Northern; Cyclic AMP; Molsidomine; Nitric Oxide; Nitroprusside; Penicillamine; Receptors, Neuropeptide Y; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured; Vasodilator Agents

1997
Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.
    FEBS letters, 1997, Aug-18, Volume: 413, Issue:2

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Microglia; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine

1997
Disrupted [Ca2+]i homeostasis contributes to the toxicity of nitric oxide in cultured hippocampal neurons.
    Journal of neurochemistry, 1997, Volume: 69, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzamides; Calcium; Cells, Cultured; Cysteine; Cysteine Proteinase Inhibitors; Dipeptides; Embryo, Mammalian; Enzyme Inhibitors; Free Radical Scavengers; Hemoglobins; Hippocampus; Homeostasis; Molsidomine; Neurons; Nitric Oxide; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Superoxide Dismutase

1997
Nitric oxide does not modulate kainate receptor binding in human brain.
    Neuroscience letters, 1997, Sep-19, Volume: 233, Issue:2-3

    Topics: Brain; Cysteine; Female; Humans; Male; Middle Aged; Molsidomine; Nitric Oxide; Penicillamine; Receptors, Kainic Acid; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols

1997
Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Animals; Apoptosis; Cell Line; Epithelial Cells; Genes, fos; Genes, jun; Hydrogen Peroxide; Lung; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Reactive Oxygen Species; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Spermine; Transcription, Genetic

1997
Active site modification of aldose reductase by nitric oxide donors.
    Biochimica et biophysica acta, 1997, Sep-05, Volume: 1341, Issue:2

    Topics: Aldehyde Reductase; Binding Sites; Borohydrides; Catalysis; Diabetes Complications; Diabetes Mellitus; Dithiothreitol; Enzyme Inhibitors; Glyceraldehyde; Humans; Kinetics; Molsidomine; Mutagenesis, Site-Directed; NADP; Nitric Oxide; Nitroprusside; Penicillamine; Placenta; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine

1997
Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation.
    Biochemical and biophysical research communications, 1997, Nov-17, Volume: 240, Issue:2

    Topics: Animals; Apoptosis; Borates; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Dactinomycin; Dithiothreitol; Humans; Kinetics; Liver; Male; Mercuric Chloride; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Tumor Necrosis Factor-alpha

1997
Lack of effect of two nitric oxide donors on hydrogen peroxide-induced endothelial barrier dysfunction.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Animals; Cattle; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Molsidomine; Nitric Oxide; Penicillamine; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine

1997
Nitric oxide donation and nitrite assays in the presence of thiols and albumin as determined by Griess' and Werringloer's methods.
    Polish journal of pharmacology, 1997, Volume: 49, Issue:4

    Topics: Amino Acids; Cysteine; Glutathione; Molsidomine; Nitric Oxide; Nitrites; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Serum Albumin, Bovine; Sodium Nitrite; Sulfhydryl Compounds

1997
Nitric oxide donor-induced apoptosis in smooth muscle cells is modulated by protein kinase C and protein kinase A.
    European journal of pharmacology, 1997, Nov-27, Volume: 339, Issue:2-3

    Topics: Animals; Aorta; Apoptosis; Cyclic AMP-Dependent Protein Kinases; Membrane Proteins; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Protein Kinase C; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1997
Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium.
    British journal of pharmacology, 1998, Volume: 123, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Cadmium; Calcium Chloride; Citrulline; Enzyme Inhibitors; Heart Rate; Hypertension; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1998
The NO/cGMP pathway and the development of neural networks in postembryonic lobsters.
    Journal of neurobiology, 1998, Feb-15, Volume: 34, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Central Nervous System; Cyclic GMP; Female; Ganglia, Invertebrate; Larva; Molsidomine; Nephropidae; Nerve Net; Nerve Tissue Proteins; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Signal Transduction; Smell

1998
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells.
    Gastroenterology, 1998, Volume: 114, Issue:3

    Topics: Adenosine Triphosphate; Caco-2 Cells; DNA Damage; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Permeability; Poly(ADP-ribose) Polymerases; S-Nitroso-N-Acetylpenicillamine

1998
Exogenous nitric oxide inhibits mesangial cell adhesion to extracellular matrix components.
    Kidney international, 1998, Volume: 53, Issue:3

    Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Cyclic GMP; Cytoskeleton; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glomerular Mesangium; Glutathione; Molsidomine; Nitric Oxide; Nitroprusside; Nitroso Compounds; Penicillamine; Protein-Tyrosine Kinases; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Signal Transduction

1998
Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:1

    Topics: Adenosine Triphosphate; Animals; Benzoates; Calcium; Cells, Cultured; Cyclic GMP; Imidazoles; Lactic Acid; Liver; Male; Molsidomine; Nitric Oxide; Nitro Compounds; Oleic Acid; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Vasodilator Agents

1998
Mechanisms of relaxations of bovine isolated bronchioles by the nitric oxide donor, GEA 3175.
    British journal of pharmacology, 1998, Volume: 123, Issue:5

    Topics: Albuterol; Aminoquinolines; Animals; Apamin; Bronchi; Bronchodilator Agents; Cattle; Charybdotoxin; Female; Glyburide; Male; Molsidomine; Muscle Relaxation; Nitric Oxide; Oxyhemoglobins; Penicillamine; Peptides; Receptors, Adrenergic, beta-2; Superoxide Dismutase; Triazoles

1998
Inhibitory effect of inducible type nitric oxide synthase on oxidative modification of low density lipoprotein by vascular smooth muscle cells.
    Atherosclerosis, 1998, Volume: 136, Issue:1

    Topics: Animals; Cells, Cultured; Copper; Electrophoresis, Agar Gel; Enzyme Induction; Enzyme Inhibitors; Humans; Kinetics; Lipoproteins, LDL; Mice; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase

1998
Evidence that different mechanisms underlie smooth muscle relaxation to nitric oxide and nitric oxide donors in the rabbit isolated carotid artery.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Acetylcholine; Animals; Apamin; Calcimycin; Carotid Arteries; Cell Membrane; Cyclic GMP; Glyburide; In Vitro Techniques; Membrane Potentials; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Peptides; Potassium Channel Blockers; Rabbits

1998
Nitric oxide donors protect cultured rat astrocytes from 1-methyl-4-phenylpyridinium-induced toxicity.
    Free radical biology & medicine, 1998, Mar-15, Volume: 24, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Astrocytes; Cells, Cultured; Free Radicals; Molsidomine; Neuroprotective Agents; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Sprague-Dawley; Rotenone

1998
Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine.
    European journal of pharmacology, 1998, Apr-03, Volume: 346, Issue:1

    Topics: Molsidomine; Nitric Oxide; Oxygen; Penicillamine; Superoxides; Triazoles; Tyrosine

1998
IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism.
    Journal of neuroimmunology, 1998, Aug-01, Volume: 88, Issue:1-2

    Topics: Brain; Cell Nucleus; Cells, Cultured; Enzyme Inhibitors; Humans; Interferon-gamma; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Transcription Factor AP-1

1998
Inhibition of clotting factor XIII activity by nitric oxide.
    Biochemical and biophysical research communications, 1998, Aug-10, Volume: 249, Issue:1

    Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Factor XIII; Glutathione; Humans; Molsidomine; Nitric Oxide; Nitroso Compounds; Penicillamine; Platelet Aggregation Inhibitors; S-Nitrosoglutathione; Spermine

1998
Treatment of Paracoccidioides brasiliensis-infected mice with a nitric oxide inhibitor prevents the failure of cell-mediated immune response.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Sep-15, Volume: 161, Issue:6

    Topics: Animals; Cell-Free System; Drug Administration Schedule; Immunity, Cellular; Injections, Intraperitoneal; Lung; Lung Diseases, Parasitic; Lymphocyte Activation; Macrophages, Alveolar; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Paracoccidioides; Paracoccidioidomycosis; Penicillamine; Spleen; Tumor Necrosis Factor-alpha

1998
Inhibitory effects of mesoionic 3-aryl substituted oxatriazole-5-imine derivatives on vascular smooth muscle cell mitogenesis and proliferation in vitro.
    British journal of pharmacology, 1998, Volume: 125, Issue:2

    Topics: Animals; Cell Division; Cells, Cultured; Cyclic GMP; DNA; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitrites; Penicillamine; Rats; Rats, Wistar; Signal Transduction; Triazoles; Urea

1998
Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite.
    Biochimica et biophysica acta, 1998, Sep-16, Volume: 1425, Issue:1

    Topics: Antioxidants; Caco-2 Cells; Epithelial Cells; Free Radical Scavengers; Glutathione; Humans; Hydroxyl Radical; Intestinal Absorption; Intestines; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Permeability; Superoxide Dismutase; Superoxides

1998
Interaction of nitric oxide donors and ascorbic acid on D-[3H] aspartate efflux from rat striatal slices.
    Neurochemical research, 1999, Volume: 24, Issue:1

    Topics: Animals; Ascorbic Acid; Aspartic Acid; Corpus Striatum; In Vitro Techniques; Kinetics; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Potassium Cyanide; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Tritium

1999
Lack of interaction between nitric oxide and the redox modulatory site of the NMDA receptor.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: Animals; Binding Sites; Cerebral Cortex; CHO Cells; Cricetinae; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Membrane Potentials; Molsidomine; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Patch-Clamp Techniques; Penicillamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins

1999
In vitro simultaneous measurements of relaxation and nitric oxide concentration in rat superior mesenteric artery.
    The Journal of physiology, 1999, Apr-01, Volume: 516 ( Pt 1)

    Topics: Acetylcholine; Animals; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Artery, Superior; Microelectrodes; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Oxyhemoglobins; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine

1999
Inhibition of bronchoprotective effects of beta2-adrenoceptor agonists by peroxynitrite in guinea pig airways.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:4 Pt 1

    Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Bronchoconstriction; Colforsin; Guinea Pigs; Isoproterenol; Male; Molsidomine; Nitrates; Penicillamine; Receptors, Adrenergic, beta-1

1999
Nitric oxide up-regulates the expression of intercellular adhesion molecule-1 on cancer cells.
    Biochemical and biophysical research communications, 1999, Apr-13, Volume: 257, Issue:2

    Topics: Benzoates; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Free Radical Scavengers; Genistein; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Staurosporine; Tongue Neoplasms; Transcription Factor AP-1; Tumor Cells, Cultured; Up-Regulation

1999
Regulation of intracellular polyamine biosynthesis and transport by NO and cytokines TNF-alpha and IFN-gamma.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: 3T3 Cells; Animals; Biological Transport; Cell Line; Cell Line, Transformed; Dithiothreitol; Enzyme Inhibitors; Interferon-gamma; Kidney Tubules, Proximal; Lysine; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Penicillamine; Polyamines; Rats; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha

1999
Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids.
    Journal of neuroimmunology, 1999, Mar-01, Volume: 95, Issue:1-2

    Topics: Animals; Central Nervous System; Dinoprost; Encephalomyelitis, Autoimmune, Experimental; F2-Isoprostanes; Lipid Peroxidation; Mice; Molsidomine; Myelin Proteins; Myelin Sheath; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Penicillamine

1999
Immunostimulated glial cells potentiate glucose deprivation-induced death of cultured rat cerebellar granule cells.
    Journal of neurotrauma, 1999, Volume: 16, Issue:5

    Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; Coculture Techniques; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glucose; Interferon-gamma; Kinetics; Lipopolysaccharides; Microtubule-Associated Proteins; Molsidomine; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine

1999
Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart.
    The Journal of physiology, 1999, Jul-15, Volume: 518 ( Pt 2)

    Topics: Aminoquinolines; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Half-Life; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Molsidomine; Muscle Fibers, Skeletal; Myocardial Contraction; Nitric Oxide Donors; Nitroprusside; Penicillamine; Rana esculenta; S-Nitroso-N-Acetylpenicillamine

1999
Up-regulation of heme-binding protein 23 (HBP23) gene expression by lipopolysaccharide is mediated via a nitric oxide-dependent signaling pathway in rat Kupffer cells.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Animals; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclic GMP; Cytochrome-B(5) Reductase; Gene Expression Regulation; Heme-Binding Proteins; Hemeproteins; Kinetics; Kupffer Cells; Lipopolysaccharides; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Penicillamine; Protein Biosynthesis; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Transcription, Genetic

1999
Nitric oxide synthase inhibitors enhance 5-HT2 receptor-mediated behavior, the head-twitch response in mice.
    Life sciences, 1999, Volume: 64, Issue:26

    Topics: Animals; Arginine; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Head Movements; Male; Methylene Blue; Mice; Mice, Inbred ICR; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1999
Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells.
    Diabetologia, 1999, Volume: 42, Issue:7

    Topics: Animals; Antioxidants; Catalase; Cytotoxicity, Immunologic; DEET; Drug Synergism; Gene Expression; Glutathione Peroxidase; Hydrogen Peroxide; Hypoxanthine; Islets of Langerhans; Molsidomine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tumor Cells, Cultured

1999
Inhibitory effect of nitric oxide on chemically induced differentiation of human leukemic K562 cells.
    Biochemical pharmacology, 1999, Sep-01, Volume: 58, Issue:5

    Topics: Antibiotics, Antineoplastic; Cell Division; Erythropoiesis; Humans; K562 Cells; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; RNA, Messenger; Tumor Cells, Cultured

1999
Elevated production of salivary nitric oxide in oral mucosal diseases.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1999, Volume: 28, Issue:8

    Topics: Adult; Cell Line; Cell Size; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Lichen Planus, Oral; Male; Molsidomine; Mouth Diseases; Mouth Mucosa; Nitric Oxide; Nitric Oxide Donors; Oral Ulcer; Penicillamine; Saliva; Salivary Glands

1999
Regulation of prostaglandin H2 synthase activity by nitrogen oxides.
    Biochemistry, 1999, Sep-21, Volume: 38, Issue:38

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cells, Cultured; Cyclooxygenase 1; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Isoenzymes; Male; Membrane Proteins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Peroxides; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine; Sheep; Superoxides

1999
Inhibition of cathepsin K by nitric oxide donors: evidence for the formation of mixed disulfides and a sulfenic acid.
    Biochemistry, 1999, Oct-12, Volume: 38, Issue:41

    Topics: Animals; Catalysis; Cathepsin K; Cathepsins; CHO Cells; Cricetinae; Disulfides; Dose-Response Relationship, Drug; Enzyme Activation; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Hydrogen-Ion Concentration; Molsidomine; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Penicillamine; Protease Inhibitors; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Sulfenic Acids; Time Factors

1999
Different effects of reactive nitrogen intermediates on prostaglandin E2 synthesis in cultured rat microglia and RAW 264.7 cells.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Arachidonic Acid; Cell Line; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Macrophages; Mice; Microglia; Molsidomine; Monocytes; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats

1999
Possible mechanism of bronchoprotection by SIN-1 in anaesthetized guinea pigs: roles of nitric oxide and peroxynitrite.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:3

    Topics: Acetylcholine; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; Male; Molsidomine; Nebulizers and Vaporizers; Nitrates; Nitric Oxide; Penicillamine; Rhodamines; Time Factors; Vasodilator Agents

2000
NO(+) but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca(2+).
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:5

    Topics: 4-Aminopyridine; Animals; Bronchi; Calcium; Calcium-Transporting ATPases; Charybdotoxin; Cyclic GMP; Dithiothreitol; Dogs; Enzyme Activation; Free Radicals; Guanylate Cyclase; Humans; In Vitro Techniques; Molsidomine; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Penicillamine; Potassium Channels; Potassium Chloride; Tetraethylammonium; Trachea

2000
Synergistic depletion of astrocytic glutathione by glucose deprivation and peroxynitrite: correlation with mitochondrial dysfunction and subsequent cell death.
    Journal of neurochemistry, 2000, Volume: 74, Issue:5

    Topics: Animals; Astrocytes; Cell Survival; Drug Synergism; Glucose; Glutathione; Membrane Potentials; Mitochondria; Molsidomine; Nitrates; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

2000
Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:5

    Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Heme Oxygenase (Decyclizing); Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Pulmonary Artery; Second Messenger Systems

2000
Contribution of adenoviral-mediated superoxide dismutase gene transfer to the reduction in nitric oxide-induced cytotoxicity on human islets and INS-1 insulin-secreting cells.
    Diabetologia, 2000, Volume: 43, Issue:5

    Topics: Adenoviridae; Animals; Cell Survival; Cells, Cultured; Genetic Vectors; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Superoxide Dismutase; Transfection; Tumor Cells, Cultured

2000
The origin of dinitrosyl-iron complex in endothelial cells.
    Annals of the New York Academy of Sciences, 2000, Volume: 899

    Topics: Animals; Cells, Cultured; Endothelium, Vascular; Iron; Molsidomine; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine

2000
Major potassium conductance in type I hair cells from rat semicircular canals: characterization and modulation by nitric oxide.
    Journal of neurophysiology, 2000, Volume: 84, Issue:1

    Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic GMP; Gluconates; Guanylate Cyclase; Hair Cells, Vestibular; Membrane Potentials; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Potassium; Potassium Channel Blockers; Rats; Rats, Long-Evans; Semicircular Canals; Signal Transduction

2000
S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules.
    European journal of pharmacology, 2000, Jul-14, Volume: 400, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Catalase; Deferoxamine; Flow Cytometry; Hydrogen Peroxide; Molsidomine; Neuroblastoma; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tumor Cells, Cultured

2000
Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:2

    Topics: Animals; Biological Transport; Cells, Cultured; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Mitogen-Activated Protein Kinases; Molsidomine; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Penicillamine; Pyridines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Stress, Mechanical

2000
Nitric oxide and peroxynitrite anion modulate liver plasma membrane fluidity and Na(+)/K(+)-ATPase activity.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:4

    Topics: Animals; Cell Fractionation; Cell Polarity; Enzyme Activation; Fluorescence Polarization; Liver; Male; Membrane Fluidity; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2000
Adaptive responses to peroxynitrite: increased glutathione levels and cystine uptake in vascular cells.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:4

    Topics: Adaptation, Physiological; Animals; Cattle; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Glutamic Acid; Glutathione; Metalloporphyrins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Nucleic Acid Synthesis Inhibitors; Penicillamine; Protein Synthesis Inhibitors; S-Nitroso-N-Acetylpenicillamine; Sodium; Superoxide Dismutase

2000
Nitric oxide donors and angiotensin-converting enzyme inhibitors act in concert to inhibit human angiotensin-converting enzyme activity and platelet aggregation in vitro.
    European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Endothelium, Vascular; Female; Humans; Molsidomine; Nitric Oxide Donors; Penicillamine; Peptidyl-Dipeptidase A; Platelet Aggregation; S-Nitroso-N-Acetylpenicillamine; Umbilical Veins

2000
NO-induced modulation of calcium-oscillations in pulmonary vascular smooth muscle.
    Cell calcium, 2000, Volume: 27, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Calcium; Cyclic GMP-Dependent Protein Kinases; Endothelin-1; Indoles; Isometric Contraction; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Penicillamine; Pulmonary Artery; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sarcoplasmic Reticulum; Vasodilation; Vasodilator Agents

2000
Various nitric oxide donors protect chick embryonic neurons from cyanide-induced apoptosis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Animals; Apoptosis; Cell Death; Cells, Cultured; Chick Embryo; Dithiothreitol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Hydrazines; Kynurenic Acid; Molsidomine; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrogen Oxides; Nitroglycerin; Nitroprusside; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Sodium Cyanide

2000
Nitric oxide inhibits Marek's disease virus replication but is not the single decisive factor in interferon-gamma-mediated viral inhibition.
    Virology, 2000, Nov-10, Volume: 277, Issue:1

    Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chick Embryo; Chickens; Chlorocebus aethiops; Coculture Techniques; COS Cells; Fibroblasts; Herpesvirus 2, Gallid; Interferon-gamma; Macrophages; Molsidomine; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Virus Replication

2000
Toxicity of nitric oxide and peroxynitrite to bacterial pathogens of fish.
    Diseases of aquatic organisms, 2000, Nov-14, Volume: 43, Issue:2

    Topics: Aeromonas; Animals; Bacterial Infections; Catalase; Cell-Free System; Fish Diseases; Free Radical Scavengers; Microbial Sensitivity Tests; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oncorhynchus mykiss; Oxidants; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase

2000
Mechanisms of nitric oxide-induced cytotoxicity in normal human hepatocytes.
    Environmental and molecular mutagenesis, 2001, Volume: 37, Issue:1

    Topics: Adult; Apoptosis; Blotting, Southern; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; DNA Damage; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electron Transport; Hepatocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Molsidomine; Mutagenicity Tests; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Reactive Oxygen Species

2001
Nitric oxide in the afferent synaptic transmission of the axolotl vestibular system.
    Neuroscience, 2001, Volume: 103, Issue:2

    Topics: Action Potentials; Ambystoma; Animals; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hair Cells, Vestibular; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Acid; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Synapses; Synaptic Transmission

2001
Nitric oxide reduces energy supply by direct action on the respiratory chain in isolated cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:5

    Topics: Adenosine; Alkaloids; Animals; Calcium; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Enzyme Inhibitors; Indoles; Molsidomine; Muscle Fibers, Skeletal; Myocardium; NAD; Nitric Oxide; Nitric Oxide Donors; Oxygen Consumption; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine

2001
NO donors inhibit Leishmania infantum cysteine proteinase activity.
    Biochimica et biophysica acta, 2001, Feb-09, Volume: 1545, Issue:1-2

    Topics: Animals; Ascorbic Acid; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dithiothreitol; Glutathione; Kinetics; Leishmania infantum; Leupeptins; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitroglycerin; Nitroprusside; Nitroso Compounds; Penicillamine; Protozoan Proteins; S-Nitrosoglutathione

2001
Immunostimulation of rat primary astrocytes decreases intracellular ATP level.
    Brain research, 2001, Jun-01, Volume: 902, Issue:2

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Central Nervous System; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Inflammation Mediators; Interferon-gamma; Intracellular Fluid; L-Lactate Dehydrogenase; Lipopolysaccharides; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured

2001
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Charybdotoxin; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Labor, Obstetric; Molsidomine; Muscle Relaxation; Muscle, Smooth; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Oxytocin; Penicillamine; Peptides; Pregnancy; Quinoxalines; S-Nitrosothiols; Scorpion Venoms; Time Factors; Uterus

2001
Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF.
    Cardiovascular research, 2001, Volume: 51, Issue:4

    Topics: Analysis of Variance; Animals; Cells, Cultured; DEET; Endothelial Growth Factors; Humans; Lymphokines; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Penicillamine; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Differential modulation of prostaglandin H synthase-2 by nitric oxide-related species in intact cells.
    Biochemistry, 2001, Sep-25, Volume: 40, Issue:38

    Topics: Animals; Astrocytes; Brain; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Isoenzymes; Lipopolysaccharides; Mice; Molsidomine; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroso Compounds; Oxidation-Reduction; Penicillamine; Prostaglandin-Endoperoxide Synthases; S-Nitroso-N-Acetylpenicillamine; Transfection

2001
Killing of lymphoblastic leukemia cells by nitric oxide and taxol: involvement of NF-kappaB activity.
    Cancer letters, 2001, Nov-08, Volume: 173, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cytoskeleton; Drug Synergism; Humans; Leukemia L1210; Leukemia, Lymphoid; Mice; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Paclitaxel; Penicillamine; Protein Synthesis Inhibitors; Pyrrolidines; Thiocarbamates; Tumor Cells, Cultured

2001
ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 444, Issue:3

    Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Calcium; Cations; Cell Line; Electrophysiology; Endothelium, Vascular; Humans; Ion Channels; Membrane Potentials; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Umbilical Veins

2002
Effects of nitric oxide donors on vascular endothelial growth factor gene induction.
    Biochemical and biophysical research communications, 2002, Aug-30, Volume: 296, Issue:4

    Topics: Blotting, Northern; Blotting, Western; Cell Nucleus; Dithiothreitol; Dose-Response Relationship, Drug; Endothelial Growth Factors; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; Lymphokines; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Oxidation-Reduction; Penicillamine; Plasmids; Promoter Regions, Genetic; Pyridines; Reducing Agents; RNA; RNA, Messenger; S-Nitrosoglutathione; Transcription Factors; Triazenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Peroxynitrite triggers a delayed resistance of coronary endothelial cells against ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Ischemic Preconditioning, Myocardial; Male; Methionine; Molsidomine; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Uric Acid

2002
Nitric oxide inhibits irreversibly P815 cell proliferation: involvement of potassium channels.
    Cell proliferation, 2002, Volume: 35, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Count; Cell Division; Coloring Agents; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gentian Violet; Growth Inhibitors; Guanylate Cyclase; Kinetics; Mastocytoma; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Potassium Channel Blockers; Potassium Channels; Tumor Cells, Cultured

2002
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
    European journal of pharmacology, 2003, Mar-19, Volume: 464, Issue:2-3

    Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases

2003
Nitric oxide disrupts VE-cadherin complex in murine microvascular endothelial cells.
    Biochemical and biophysical research communications, 2003, Apr-25, Volume: 304, Issue:1

    Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cell Line; Endothelium, Vascular; Macromolecular Substances; Male; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; RNA, Messenger; Skin

2003
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
    British journal of pharmacology, 2004, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine

2004
Comparison of toxic effects of nitric oxide and peroxynitrite on Uronema marinum (Ciliata: Scuticociliatida).
    Diseases of aquatic organisms, 2004, Mar-10, Volume: 58, Issue:2-3

    Topics: Animals; Catalase; Ciliophora; Dose-Response Relationship, Drug; Hemoglobins; Molsidomine; Nitric Oxide Donors; Penicillamine; Superoxide Dismutase

2004
Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania.
    Parasitology research, 2005, Volume: 96, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Leishmania donovani; Leishmania major; Mice; Mice, Inbred BALB C; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; Peroxynitrous Acid

2005
Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells.
    FEBS letters, 2005, Jun-06, Volume: 579, Issue:14

    Topics: Cell Line; Collagenases; Enzyme Activation; Hepatocytes; Humans; I-kappa B Proteins; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Molsidomine; NF-kappa B; NF-KappaB Inhibitor alpha; Nitrates; Penicillamine; Peroxynitrous Acid; Phosphorylation; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2005
Reactive nitrogen species induce nuclear factor-kappaB-mediated protein degradation in skeletal muscle cells.
    Free radical biology & medicine, 2006, Jun-15, Volume: 40, Issue:12

    Topics: Animals; Antioxidants; Cells, Cultured; Metalloendopeptidases; Molsidomine; Muscle Cells; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; NF-kappa B; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Rats; Reactive Nitrogen Species; Tyrosine; Ubiquitin

2006
Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP.
    Experimental neurology, 2006, Volume: 202, Issue:2

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Cortical Spreading Depression; Cyclic GMP; Drug Interactions; Hypercapnia; Laser-Doppler Flowmetry; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Spermine; Thionucleotides; Time Factors

2006
The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-kappaB and implication to inflammatory processes.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 4

    Topics: Animals; Cell Line; Cells, Cultured; Humans; Inflammation; Lymphocytes; Molsidomine; NF-kappa B; Nicotiana; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Rats; Smoke

2006
Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers.
    Journal of neuroscience research, 2007, Aug-01, Volume: 85, Issue:10

    Topics: Aldehydes; Animals; Cell Respiration; Cerebral Cortex; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Transport Complex I; Free Radical Scavengers; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitochondria; Molsidomine; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Penicillamine; Peroxynitrous Acid; Protein Carbonylation; Spin Labels; Tyrosine

2007
Neuroglobin protects against nitric oxide toxicity.
    Neuroscience letters, 2008, Jan-10, Volume: 430, Issue:2

    Topics: Animals; Cell Death; Cell Line, Transformed; Dose-Response Relationship, Drug; Globins; Mice; Molsidomine; Nerve Tissue Proteins; Neuroglobin; Neurons; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Transfection

2008
Peroxynitrite has potent pulmonary vasodilator activity in the rat.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Male; Molsidomine; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Peroxynitrous Acid; Pulmonary Artery; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents

2012