linsidomine has been researched along with 8-bromocyclic gmp in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 43 (70.49) | 18.2507 |
| 2000's | 18 (29.51) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Till, U | 1 |
| Chap, H; Gassama-Diagne, A; Simon, MF | 1 |
| Bucher, B; Ouedraogo, S; Paya, D; Stoclet, JC; Tschöpl, M | 1 |
| Alam, AS; Datta, HK; Hecker, M; Lidbury, PS; MacIntyre, I; Moonga, BS; Vane, JR; Zaidi, M | 1 |
| Giles, WR; Han, X; Shimoni, Y | 1 |
| Iadecola, C; Xu, X; Zhang, F | 1 |
| Garg, LC; Guzman, NJ; Madsen, KM; Tisher, CC; Tojo, A | 1 |
| Maronde, E; Mayer, B; Middendorff, R; Olcese, J | 1 |
| Neumannova, V; Ponka, P; Richardson, DR | 1 |
| Johnston, HM; Morris, BJ | 2 |
| Bouriquet, N; Casellas, D | 1 |
| Andre, A; Andriantsitohaina, R; Lagaud, GJ; Muller, B; Stoclet, JC | 1 |
| Brian, JE; Hicks, KK; Kennedy, RH; Seifen, E | 1 |
| Becquet, F; Courtois, Y; Goureau, O | 1 |
| Hess, DT; Patterson, SI; Skene, JH; Smith, DS | 1 |
| Kubes, P | 1 |
| Brutsaert, DL; Mohan, P; Paulus, WJ; Sys, SU | 1 |
| Fandrey, J; Hoffmann, G; Schobersberger, W | 1 |
| Ikeda, M; Ikeda, U; Kano, S; Minota, S; Shimada, K; Takahashi, M | 1 |
| Garland, CJ; Hurrell, A; Jeremy, JY; Plane, F | 1 |
| Boss, GR; Pascual, FE; Pilz, RB; Suhasini, M | 1 |
| Hempel, A; Hölschermann, H; Noll, T; Piper, HM | 1 |
| Funayama, H; Ikeda, U; Kano, S; Masuyama, J; Shimada, K; Takahashi, M | 1 |
| Iadecola, C; Yang, G | 1 |
| Katusic, ZS; Onoue, H | 2 |
| Baux, G; Fossier, P; Mothet, JP; Schirar, A; Tauc, L | 1 |
| Nishizawa, S; Ryu, H; Uemura, K; Yamamoto, S; Yokoyama, T | 1 |
| Dietl, P; Friedrich, F; Hoffmann, G; Schobersberger, W; Völkl, H | 1 |
| Kinoshita, M; Liu, Q; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M; Takaoka, A | 1 |
| Nishizawa, S; Uemura, K; Yamamoto, S; Yokoyama, T | 1 |
| Cantabrana, B; Hidalgo, A; Menéndez Antolin, L; Pérez Vallina, JR; Sánchez, M | 1 |
| Gauer, S; Pröls, F; Schoecklmann, HO; Sterzel, RB; Yao, J | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Galland, A | 1 |
| Allescher, HD; Franck, H; Puschmann, A; Schusdziarra, V; Storr, M | 1 |
| Fujino, MA; Hosoda, K; Owyang, C; Takahashi, T | 1 |
| Brüne, B; Callsen, D; Pfeilschifter, J | 1 |
| Fernández-Tomé, P; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Charles, SL; Salt, TE; Shaw, PJ | 1 |
| Immenschuh, S; Iwahara, S; Ramadori, G; Stritzke, J | 1 |
| Chen, SJ; Wu, CC; Yen, MH | 1 |
| Kankaanranta, H; Kosonen, O; Malo-Ranta, U; Moilanen, E | 1 |
| Baribeau, J; Berkenbosch, JW; Perreault, T | 1 |
| Cox, G; Janssen, LJ; Keshavjee, S; Lu-Chao, H; Premji, M | 1 |
| Abate, A; Dennery, PA; Polte, T; Schröder, H | 1 |
| Chen, Q; Gole, M; Gow, AJ; Ischiropoulos, H; Lee, VM; Themistocleous, M | 1 |
| Andersson, K; Fujiwara, M; Persson, K | 1 |
| Rehder, V; Van Wagenen, S | 1 |
| Prado, WA; Sousa, AM | 1 |
| Decking, UK; Schrader, J; Stumpe, T | 1 |
| Kim, JH; Kim, SB; Lee, SK; Park, JS; Park, SK; Yang, WS | 1 |
| Graier, WF; Groschner, K; Malli, R; Schmidt, K; Thyagarajan, B | 1 |
| Brading, AF; Deka, DK | 1 |
| Eldred, WD; Yu, D | 1 |
| Elmedal Laursen, B; Mulvany, MJ; Simonsen, U | 1 |
| Almanza, A; Navarrete, F; Soto, E; Vega, R | 1 |
| Kiagiadaki, F; Mastrodimou, N; Thermos, K | 1 |
| Acierno, R; Amelio, D; Gattuso, A; Guerrieri, A; Mannarino, C; Tota, B | 1 |
| Carletti, F; D'Agostino, S; Ferraro, G; Lonobile, G; Rizzo, V; Sardo, P | 1 |
| Kim, JM; Kim, SY; Koo, JY; Koo, YK; Oh, D; Park, S; Yun-Choi, HS | 1 |
1 trial(s) available for linsidomine and 8-bromocyclic gmp
| Article | Year |
|---|---|
Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro.
Topics: Adult; Antithrombins; Arginine; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Humans; In Vitro Techniques; Infusions, Intravenous; Male; Molsidomine; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2; Thromboxane B2; Thromboxanes | 1998 |
60 other study(ies) available for linsidomine and 8-bromocyclic gmp
| Article | Year |
|---|---|
Nitrovasodilators inhibit thrombin-induced platelet-activating factor synthesis in human endothelial cells.
Topics: Acetyltransferases; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Humans; Molsidomine; Nitroprusside; Platelet Activating Factor; Thrombin | 1992 |
Inhibition of platelet arachidonic acid liberation by endothelium-derived relaxing factor (EDRF) as studied with sin-1, a nitric oxide generating drug. Evidence for calcium-dependent and calcium-independent mechanisms.
Topics: Arachidonic Acid; Blood Platelets; Calcium; Cyclic GMP; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Molsidomine; Nitric Oxide; Phospholipases A; Phospholipases A2; Thrombin | 1992 |
Role of the L-arginine-NO pathway and of cyclic GMP in electrical field-induced noradrenaline release and vasoconstriction in the rat tail artery.
Topics: Animals; Arginine; Arteries; Atrial Natriuretic Factor; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Purinones; Rats; Tail; Vasoconstriction; Vasodilator Agents | 1992 |
Osteoclastic inhibition: an action of nitric oxide not mediated by cyclic GMP.
Topics: Animals; Animals, Newborn; Bone Resorption; Calcitonin; Calcium; Cell Membrane; Cells, Cultured; Cyclic GMP; Cytosol; Dibutyryl Cyclic GMP; Ionomycin; Kinetics; Molsidomine; Nitric Oxide; Osteoclasts; Rats; Rats, Inbred Strains; Vasodilator Agents | 1991 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
SIN-1 reverses attenuation of hypercapnic cerebrovasodilation by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebrovascular Circulation; Cyclic GMP; Hypercapnia; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Papaverine; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Nitric oxide inhibits bafilomycin-sensitive H(+)-ATPase activity in rat cortical collecting duct.
Topics: Amino Acid Oxidoreductases; Animals; Anti-Bacterial Agents; Arginine; Cyclic GMP; Enzyme Induction; Ethylmaleimide; Female; In Vitro Techniques; Interferon-gamma; Kidney Tubules, Collecting; Kinetics; Lipopolysaccharides; Macrolides; Macrophages; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Vacuoles | 1994 |
The effect of NO-donors in bovine and rat pineal cells: stimulation of cGMP and cGMP-independent inhibition of melatonin synthesis.
Topics: Animals; Cattle; Cells, Cultured; Cyclic GMP; Isoproterenol; Melatonin; Molsidomine; Nitric Oxide; Nitroprusside; Pineal Gland; Rats; Stimulation, Chemical | 1995 |
Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells.
Topics: Animals; Cell Line; Cyclic GMP; Humans; Iodine Radioisotopes; Iron; Iron Radioisotopes; Melanoma; Mice; Molsidomine; Nitric Oxide; Nitrites; Nitroprusside; Thymidine; Transferrin | 1995 |
Selective regulation of dendritic MAP2 mRNA levels in hippocampal granule cells by nitric oxide.
Topics: Animals; Base Sequence; Cyclic GMP; Cytoskeleton; Dendrites; Gene Expression Regulation; Hippocampus; Male; Microtubule-Associated Proteins; Molecular Sequence Data; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Receptors, Glutamate; RNA, Messenger | 1994 |
Interaction between cGMP-dependent dilators and autoregulation in rat preglomerular vasculature.
Topics: Animals; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Homeostasis; Kidney Glomerulus; Male; Molsidomine; Nitroprusside; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasodilator Agents | 1995 |
Effects of cGMP on calcium handling in ATP-stimulated rat resistance arteries.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Male; Mesenteric Arteries; Molsidomine; Myosins; Nitrendipine; Nitroprusside; Phosphorylation; Rats; Rats, Wistar; Terpenes; Thapsigargin; Vascular Resistance; Vasoconstriction | 1995 |
Nitric oxide has no chronotropic effect in right atria isolated from rat heart.
Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Guanylate Cyclase; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Norepinephrine; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasodilator Agents | 1994 |
Nitric oxide alters proenkephalin and prodynorphin gene expression in hippocampal granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Cyclic GMP; Dendrites; Enkephalins; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Molecular Sequence Data; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Protein Precursors; Rats; RNA, Messenger; Vasodilator Agents | 1994 |
Nitric oxide decreases in vitro phagocytosis of photoreceptor outer segments by bovine retinal pigmented epithelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cyclic GMP; Interferon-gamma; Lipopolysaccharides; Molsidomine; Nitric Oxide; Phagocytosis; Pigment Epithelium of Eye; Rod Cell Outer Segment | 1994 |
Neuronal growth cone collapse and inhibition of protein fatty acylation by nitric oxide.
Topics: Acylation; Animals; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; Ganglia, Spinal; Hemoglobins; Molsidomine; Nerve Crush; Nerve Tissue Proteins; Neurites; Neurons; Nitric Oxide; Palmitic Acid; Palmitic Acids; PC12 Cells; Rats; Sciatic Nerve; Time Factors; Vasodilator Agents | 1993 |
Nitric oxide-induced microvascular permeability alterations: a regulatory role for cGMP.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Capillary Permeability; Cats; Cyclic GMP; Intestines; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow | 1993 |
Myocardial contractile response to nitric oxide and cGMP.
Topics: Animals; Cats; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Molsidomine; Myocardial Contraction; Nitric Oxide; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine | 1996 |
Nitric oxide donors suppress erythropoietin production in vitro.
Topics: Carcinoma, Hepatocellular; Cyclic GMP; Cytokines; Erythropoietin; Humans; Hydrogen Peroxide; Liver Neoplasms; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured | 1996 |
Nitric oxide inhibits intracellular adhesion molecule-1 expression in rat mesangial cells.
Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Glomerular Mesangium; Intercellular Adhesion Molecule-1; Interleukin-1; Male; Molsidomine; Nitric Oxide; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
Evidence that potassium channels make a major contribution to SIN-1-evoked relaxation of rat isolated mesenteric artery.
Topics: Animals; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilator Agents | 1996 |
Nitric oxide-releasing agents and cGMP analogues inhibit murine erythroleukemia cell differentiation and suppress erythroid-specific gene expression: correlation with decreased DNA binding of NF-E2 and altered c-myb mRNA expression.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Animals; Base Sequence; Cell Differentiation; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyclic GMP; Dimethyl Sulfoxide; DNA-Binding Proteins; Erythroid-Specific DNA-Binding Factors; GATA1 Transcription Factor; Gene Expression Regulation, Neoplastic; Globins; Leukemia, Erythroblastic, Acute; Mice; Molecular Sequence Data; Molsidomine; NF-E2 Transcription Factor; NF-E2 Transcription Factor, p45 Subunit; Nitric Oxide; Nuclear Proteins; Oligonucleotide Probes; Oncogenes; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Purinones; Recombinant Proteins; RNA, Messenger; Thionucleotides; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Dual role of cGMP in modulation of macromolecule permeability of aortic endothelial cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Calcium; Capillary Permeability; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Extracellular Space; Guanylate Cyclase; Macromolecular Substances; Molsidomine; Serum Albumin; Stimulation, Chemical; Swine | 1997 |
Nitric oxide attenuates adhesion molecule expression in human endothelial cells.
Topics: Cell Adhesion; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Molsidomine; Nitric Oxide; RNA, Messenger; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1996 |
Obligatory role of NO in glutamate-dependent hyperemia evoked from cerebellar parallel fibers.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebellum; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Glutamic Acid; Hyperemia; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Papaverine; Partial Pressure; Penicillamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Vasodilation | 1997 |
Role of potassium channels in relaxations of canine middle cerebral arteries induced by nitric oxide donors.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 4-Aminopyridine; Animals; Barium Compounds; Cerebral Arteries; Charybdotoxin; Chlorides; Cyclic GMP; Diltiazem; Dogs; Glyburide; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Potassium Channels; Purinones; Vasodilation; Vasodilator Agents | 1997 |
Opposite effects of nitric oxide on identified inhibitory and excitatory cholinergic synapses of Aplysia californica.
Topics: Acetylcholine; Action Potentials; Animals; Aplysia; Arginine; Calcium Channels; Cholinergic Agonists; Cholinergic Antagonists; Cyclic GMP; Ganglia, Invertebrate; Ganglia, Parasympathetic; Guanylate Cyclase; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Synapses; Synaptic Transmission | 1996 |
Subarachnoid hemorrhage impairs cerebral blood flow response to nitric oxide but not to cyclic GMP in large cerebral arteries.
Topics: Animals; Brain; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Cyclic GMP; Injections, Intra-Articular; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Papaverine; Phenylephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Subarachnoid Hemorrhage; Time Factors; Vasodilator Agents | 1997 |
Nitric oxide donors inhibit spontaneous depolarizations by L-type Ca2+ currents in alveolar epithelial cells.
Topics: Aminoquinolines; Animals; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cyclic GMP; Enzyme Inhibitors; Epithelium; Guanylate Cyclase; Kinetics; Membrane Potentials; Microelectrodes; Molsidomine; Nitroprusside; Penicillamine; Pulmonary Alveoli; Rats; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Strontium; Time Factors | 1997 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Pyrroles; Vasodilator Agents | 1997 |
Dysfunction of nitric oxide induces protein kinase C activation resulting in vasospasm after subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Cyclic GMP; Dogs; Enzyme Activation; Enzyme Inhibitors; Female; Immunoenzyme Techniques; Ischemic Attack, Transient; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Protein Kinase C; Reference Values; Subarachnoid Hemorrhage | 1997 |
Nitric oxide and cyclic nucleotides participate in the relaxation of diclofenac on rat uterine smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Enzyme Inhibitors; Female; GTP-Binding Proteins; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Nucleotides, Cyclic; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Rats, Wistar; Sensitivity and Specificity; Sulfonamides; Uterine Contraction; Uterus; Vanadates; Vasodilator Agents; Virulence Factors, Bordetella | 1998 |
Subarachnoid hemorrhage and the role of potassium channels in relaxations of canine basilar artery to nitrovasodilators.
Topics: 4-Aminopyridine; Animals; Basilar Artery; Charybdotoxin; Cyclic GMP; Dogs; Female; Humans; Male; Molsidomine; Nitroprusside; Potassium Channels; Subarachnoid Hemorrhage; Uridine Triphosphate; Vasodilation; Vasodilator Agents | 1998 |
Exogenous nitric oxide inhibits mesangial cell adhesion to extracellular matrix components.
Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Cyclic GMP; Cytoskeleton; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glomerular Mesangium; Glutathione; Molsidomine; Nitric Oxide; Nitroprusside; Nitroso Compounds; Penicillamine; Protein-Tyrosine Kinases; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Signal Transduction | 1998 |
Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Apamin; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Charybdotoxin; Cyclic GMP; Egtazic Acid; Glyburide; Ileum; In Vitro Techniques; Indoles; Kinetics; Male; Molsidomine; Muscle Contraction; Muscle, Smooth; Peptides; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin; Thionucleotides | 1998 |
Inhibitory effects of nitric oxide donors on nitric oxide synthesis in rat gastric myenteric plexus.
Topics: Animals; Calcium Channels; Citrulline; Cyclic GMP; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Molsidomine; Muscle Relaxation; Myenteric Plexus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Stomach; Vasoactive Intestinal Peptide | 1998 |
Rapid and delayed p42/p44 mitogen-activated protein kinase activation by nitric oxide: the role of cyclic GMP and tyrosine phosphatase inhibition.
Topics: Acetylcysteine; Animals; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic GMP; Enzyme Activation; Free Radical Scavengers; Glomerular Mesangium; Glutathione; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molsidomine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Onium Compounds; Oxadiazoles; Oxazines; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Rats; S-Nitrosoglutathione; Second Messenger Systems | 1998 |
Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP.
Topics: Animals; Cell Death; Cyclic GMP; Drug Synergism; Enzyme Inhibitors; Hydrogen Peroxide; Molsidomine; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilator Agents | 1998 |
Actions of 8-bromo-cyclic-GMP on neurones in the rat thalamus in vivo and in vitro.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Geniculate Bodies; Guanylate Cyclase; In Vitro Techniques; Molsidomine; N-Methylaspartate; Neurons, Afferent; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar | 1999 |
Up-regulation of heme-binding protein 23 (HBP23) gene expression by lipopolysaccharide is mediated via a nitric oxide-dependent signaling pathway in rat Kupffer cells.
Topics: Animals; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclic GMP; Cytochrome-B(5) Reductase; Gene Expression Regulation; Heme-Binding Proteins; Hemeproteins; Kinetics; Kupffer Cells; Lipopolysaccharides; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Penicillamine; Protein Biosynthesis; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Transcription, Genetic | 1999 |
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Apamin; Calcium; Charybdotoxin; Cromakalim; Cyclic GMP; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred WKY | 1999 |
Nitric oxide-releasing compounds inhibit neutrophil adhesion to endothelial cells.
Topics: Animals; CD11 Antigens; CD18 Antigens; Cell Adhesion; Coculture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Molsidomine; Neutrophils; Nitric Oxide Donors; Rabbits; Thionucleotides; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Decreased synthesis and vasodilation to nitric oxide in piglets with hypoxia-induced pulmonary hypertension.
Topics: Animals; Animals, Newborn; Arginine; Blood Vessels; Cyclic GMP; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Circulation; Swine; Vasodilation; Vasodilator Agents | 2000 |
NO(+) but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca(2+).
Topics: 4-Aminopyridine; Animals; Bronchi; Calcium; Calcium-Transporting ATPases; Charybdotoxin; Cyclic GMP; Dithiothreitol; Dogs; Enzyme Activation; Free Radicals; Guanylate Cyclase; Humans; In Vitro Techniques; Molsidomine; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Penicillamine; Potassium Channels; Potassium Chloride; Tetraethylammonium; Trachea | 2000 |
Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Heme Oxygenase (Decyclizing); Molsidomine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Pulmonary Artery; Second Messenger Systems | 2000 |
Two distinct mechanisms of nitric oxide-mediated neuronal cell death show thiol dependency.
Topics: Acetylcysteine; Animals; Cell Death; Cell Differentiation; Cell Line; Cell Survival; Cyclic GMP; Hydrazines; Molsidomine; Necrosis; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Sulfhydryl Compounds | 2000 |
Nitric oxide-induced cGMP accumulation in the mouse bladder is not related to smooth muscle relaxation.
Topics: Animals; Arginine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phosphodiesterase Inhibitors; Piperazines; Piperidines; Purines; Quinazolines; Sildenafil Citrate; Sulfones; Urethra; Urinary Bladder | 2000 |
Regulation of neuronal growth cone filopodia by nitric oxide depends on soluble guanylyl cyclase.
Topics: Animals; Cells, Cultured; Cyclic GMP; Ganglia, Invertebrate; Growth Cones; Guanylate Cyclase; Molsidomine; NADPH Dehydrogenase; Nervous System; Nitric Oxide; Nitric Oxide Donors; Potassium Chloride; Snails | 2001 |
The dual effect of a nitric oxide donor in nociception.
Topics: Animals; Chronic Disease; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemoglobins; Injections, Spinal; Ligation; Male; Molsidomine; Nerve Compression Syndromes; Neuralgia; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Sciatic Nerve | 2001 |
Nitric oxide reduces energy supply by direct action on the respiratory chain in isolated cardiomyocytes.
Topics: Adenosine; Alkaloids; Animals; Calcium; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Enzyme Inhibitors; Indoles; Molsidomine; Muscle Fibers, Skeletal; Myocardium; NAD; Nitric Oxide; Nitric Oxide Donors; Oxygen Consumption; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 2001 |
Exogenous nitric oxide inhibits VCAM-1 expression in human peritoneal mesothelial cells. Role of cyclic GMP and NF-kappaB.
Topics: Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Humans; Interleukin-1; Lipopolysaccharides; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Peritoneum; Signal Transduction; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
Topics: Barium; Calcium; Cell Line; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Oxygen Consumption; Peroxynitrous Acid; Quinoxalines; Thapsigargin; Time Factors | 2002 |
Nitric oxide activates glibenclamide-sensitive K+ channels in urinary bladder myocytes through a c-GMP-dependent mechanism.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glyburide; Guinea Pigs; Indoles; Ion Channel Gating; Male; Membrane Potentials; Molsidomine; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Potassium Channels; Quinoxalines; Signal Transduction; Urinary Bladder | 2004 |
Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cadmium; Citrulline; Cyclic GMP; DEET; Dizocilpine Maleate; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Immunohistochemistry; In Vitro Techniques; Molsidomine; Neural Inhibition; Nipecotic Acids; Nitric Oxide; Potassium; Retina; Silver Staining; Thiourea; Turtles; Vigabatrin | 2005 |
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor.
Topics: Animals; Bronchi; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Ouabain; Oxadiazoles; Peptides; Potassium; Quinoxalines; S-Nitrosoglutathione; Serotonin; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Triazoles | 2006 |
Modulation of voltage-gated Ca2+ current in vestibular hair cells by nitric oxide.
Topics: Animals; Calcium Channels, L-Type; Carbazoles; Cell Separation; Cyclic GMP; Data Interpretation, Statistical; Enzyme Inhibitors; Ethylmaleimide; Free Radical Scavengers; Hair Cells, Vestibular; In Vitro Techniques; Indoles; Molsidomine; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Signal Transduction | 2007 |
The role of nitric oxide and cGMP in somatostatin's protection against retinal ischemia.
Topics: Animals; Choline O-Acetyltransferase; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fluorescent Antibody Technique, Indirect; In Situ Nick-End Labeling; Ischemia; Molsidomine; Nitric Oxide; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Vessels; Somatostatin; Spermine | 2008 |
Nitric oxide modulates the frog heart ventricle morphodynamics.
Topics: Animals; Anura; Arginine; Cyclic GMP; Female; Heart Ventricles; In Vitro Techniques; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Serine; Software; Ventricular Function | 2008 |
Nitric oxide- and cGMP-active compounds affect the discharge of substantia nigra pars reticulata neurons: in vivo evidences in the rat.
Topics: Action Potentials; Animals; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Iontophoresis; Male; Molsidomine; Neural Inhibition; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Signal Transduction; Substantia Nigra; Up-Regulation | 2009 |
Elevated plasma concentration of NO and cGMP may be responsible for the decreased platelet aggregation and platelet leukocyte conjugation in platelets hypo-responsive to catecholamines.
Topics: Adenosine Triphosphate; Adult; Asian People; Blood Platelets; Catecholamines; Cyclic AMP; Cyclic GMP; Female; Humans; Leukocyte Common Antigens; Leukocytes; Male; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Platelet Aggregation; Platelet Aggregation Inhibitors; Young Adult | 2009 |