Page last updated: 2024-08-16

linsidomine and 3-nitrotyrosine

linsidomine has been researched along with 3-nitrotyrosine in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (10.71)18.2507
2000's40 (71.43)29.6817
2010's10 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duran, D; Horwitz, J; Ischiropoulos, H1
Hemmens, B; Leopold, E; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER1
Brady, T; D'Ambrosio, SM; Oberyszyn, TM; Robertson, FM; Ross, MS1
Celan, I; Chazotte, L; Mower, HF; Ohshima, H; Pignatelli, B1
Maeda, S; Saeki, M1
Grisham, MB; Koyama, S; Robbins, RA; Sato, E; Simpson, KL2
Basiouny, KF; Crow, JP; Matalon, S; Zhu, S1
Daiber, A; Herold, S; Namgaladze, D; Peterson, JA; Schöneich, C; Ullrich, V1
Camhi, SL; Koyama, S; Nelson, DK; Robbins, RA; Sato, E1
Douglass, LW; Ledbetter, TK; Paape, MJ1
Camhi, SL; Hoyt, JC; Nelson, DK; Robbins, RA; Robinson, VK; Sato, E1
Berrih-Aknin, S; Gaudry-Talarmain, YM; Moulian, N; Serraf, A; Truffault, F1
Bian, K; Murad, F1
Gupta, MP; Hart, CM; Knepler, JL; Ober, MD; Patterson, C; Pavalko, F; Taher, LN1
Ducrocq, C; Gaudry-Talarmain, YM; Guermonprez, L1
Hewett, SJ; Trackey, JL; Uliasz, TF1
Bridges, CC; El-Sherbeny, A; Ganapathy, V; Ola, MS; Prasad, PD; Smith, SB1
Choi, CR; Choi, JW; Jang, ES; Ju, C; Kim, HC; Kim, WK; Ko, KH; Shin, CY1
Kato, Y; Maruyama, W; Naoi, M; Sato, Y; Shamoto-Nagai, M; Tanaka, M; Yamamoto, T; Yi, H1
Folkerts, G; Habernickel, J; Muijsers, RB; Nijkamp, FP; Postma, DS; van der Veeken, A1
Choi, JS; Chung, HY; Kim, AR; Kim, JE; Zou, Y1
Brimer, CM; Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV; Zborek, A1
Bao, F; DeWitt, DS; Liu, D; Prough, DS1
Burch, P; Heintz, NH; Janssen-Heininger, Y; Schellekens, H; Warner, L; Yuan, Z1
Clements, MK; Hanson, AJ; Nelson-Overton, LK; Quinn, MT; Rohn, TT; Siemsen, DW; Swain, SD1
Aoyagi, K; Cho, EJ; Rhyu, DY; Yokozawa, T1
Hiramoto, K; Kikugawa, K; Ohkawa, T1
Antunes, E; De Nucci, G; Marcondes, S; Moreira, J; Thomazzi, SM1
Ayuk, PT; Glazier, JD; Greenwood, SL; Khullar, S; McCord, N1
Crow, JP; Mogal, A; Nielsen, VG; Parks, DA; Zhou, F1
Austin, RC; Dickhout, JG; Hossain, GS; Lhoták, S; Pozza, LM; Zhou, J1
Aureliano, M; Gutiérrez-Merino, C; Ramos, S; Tiago, T1
Aureliano, M; Gutiérrez-Merino, C; Martín-Romero, FJ; Simão, S; Tiago, T1
Doke, N; Kawakita, K; Saito, S; Yamamoto-Katou, A; Yoshioka, H1
El Bohi, K; Fujita, S; Ishizuka, M; Kazusaka, A; Muzandu, K; Sakamoto, KQ; Shaban, Z1
Pollard, SE; Spencer, JP; Whiteman, M1
Christopher, TA; Coletti, C; Gao, E; Hu, A; Koch, W; Lopez, BL; Ma, XL; Tao, L; Wang, Y1
Idell, S; Liu, MC; Yasuda, S1
Hall, ED; Singh, IN; Sullivan, PG1
Ariz, I; Arrese-Igor, C; Auzmendi, I; González, EM; Larrainzar, E; Moran, JF; Urarte, E1
Ashki, N; Bao, F; Hayes, KC1
Asatryan, L; Gallaher, TK; Hamilton, RT; Hsiai, TK; Isas, JM; Nilsen, JT; Sawamura, T1
Arai, T; Fujieda, S; Kobayashi, S; Kuramochi, K; Nakajima, M; Nakazaki, A; Ohnishi, K; Saitoh, Y; Sugawara, F; Takeuchi, T; Watanabe, N1
Belaaouaj, A; Crouch, EC; Gao, Z; Kirk, M; Matalon, S; McDonald, B; Shrestha, K; Smith, K; Waldheuser, S1
Boos, N; Hottiger, M; Poveda, L; Wuertz, K1
Antunes, E; Cardoso, MH; De Nucci, G; Lilla, S; Marcondes, S; Morganti, RP; Murad, F1
Bi, L; Chen, H; Li, Y; Liu, X; Mao, Z; Qu, L; Xiong, J1
Chen, ML; Fan, Q; Ge, YG; Irwin, MG; Liu, SH; Liu, Y; Wang, LF; Wang, W; Xia, Z; Yang, XC; Zhang, LK1
Chen, CC; Hsu, YJ; Lee, TM1
Enerson, BE; Lawton, MP; Peters, D; Sheth, CM; Weaver, JL1
Gao, Z; Lu, N; Zhang, Y; Zhao, Y1
Hemanth Kumar, K; Khanum, F; Pal, A; Tamatam, A1
Alameda, F; Alcolea, D; Boada, M; Bosch-Morató, M; Elosúa, R; Eraso-Pichot, A; Fernández-Busquets, X; Fortea, J; Guivernau, B; Ill-Raga, G; Lleó, A; Muñoz, FJ; Nuñez, L; Paez, A; Palomer, E; Ramos-Fernández, E; Román-Dégano, I; Tajes, M; Valverde, MA1
Al-Hashimi, F; Al-Shboul, OA; Al-Shehabat, M; Mohammad, M; Mustafa, A; Yousef, A1
Akbarali, HI; Gade, A; Hashimoto, A; Kang, M1

Reviews

1 review(s) available for linsidomine and 3-nitrotyrosine

ArticleYear
Use of recombinant iron-superoxide dismutase as a marker of nitrative stress.
    Methods in enzymology, 2008, Volume: 437

    Topics: Antibodies; Biomarkers; Enzyme Activation; Immunohistochemistry; Molsidomine; Nitro Compounds; Nitrosation; Oxidative Stress; Recombinant Proteins; Serum Albumin, Bovine; Superoxide Dismutase; Tyrosine

2008

Trials

1 trial(s) available for linsidomine and 3-nitrotyrosine

ArticleYear
Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans.
    Clinical science (London, England : 1979), 2011, Volume: 120, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Ischemic Postconditioning; Leukocyte Count; Male; Malondialdehyde; Middle Aged; Molsidomine; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tyrosine; Ventricular Function, Left

2011

Other Studies

54 other study(ies) available for linsidomine and 3-nitrotyrosine

ArticleYear
Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells.
    Journal of neurochemistry, 1995, Volume: 65, Issue:5

    Topics: Animals; Dihydroxyphenylalanine; Molsidomine; Nitrates; Oxidation-Reduction; PC12 Cells; Rats; Tyrosine

1995
Interference of carboxy-PTIO with nitric oxide- and peroxynitrite-mediated reactions.
    Free radical biology & medicine, 1997, Volume: 22, Issue:5

    Topics: Animals; Benzoates; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Free Radical Scavengers; Imidazoles; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Serum Albumin, Bovine; Swine; Tyrosine

1997
Sensitivity of human hepatocytes in culture to reactive nitrogen intermediates.
    Biochemical and biophysical research communications, 1997, Apr-17, Volume: 233, Issue:2

    Topics: Cells, Cultured; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Molsidomine; Nitrites; Nitrogen; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Tyrosine

1997
Analysis of 3-nitrotyrosine in biological fluids and protein hydrolyzates by high-performance liquid chromatography using a postseparation, on-line reduction column and electrochemical detection: results with various nitrating agents.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:2

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Hypochlorous Acid; Indicators and Reagents; Molsidomine; Nitrates; Nitrites; Nitrogen Oxides; Serum Albumin, Bovine; Sodium Nitrite; Spectrophotometry, Ultraviolet; Spermine; Tyrosine

1999
p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite.
    Neuroscience research, 1999, Volume: 33, Issue:4

    Topics: Crk-Associated Substrate Protein; Humans; Molsidomine; Neuroblastoma; Nitrates; Nitric Oxide Donors; Oxidants; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured; Tyrosine

1999
Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro.
    The American journal of pathology, 1999, Volume: 155, Issue:2

    Topics: Chemokine CCL5; Chemotaxis; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrazines; Interleukin-5; Leukotriene B4; Molsidomine; Nitrates; Nitric Oxide; Nitrogen; Pteridines; Reactive Oxygen Species; Superoxides; Tyrosine; Xanthine

1999
Reactive nitrogen and oxygen species attenuate interleukin- 8-induced neutrophil chemotactic activity in vitro.
    The Journal of biological chemistry, 2000, Apr-14, Volume: 275, Issue:15

    Topics: Chemotaxis, Leukocyte; Humans; Interleukin-8; Leukotriene B4; Molsidomine; Neutrophils; Nitrates; Nitric Oxide Donors; Tyrosine

2000
Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:5

    Topics: Carbon Dioxide; Cells, Cultured; Enzyme Activation; Epithelial Cells; Humans; Hypercapnia; Lipid Metabolism; Lipopolysaccharides; Macrophages, Alveolar; Mass Spectrometry; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Respiratory Distress Syndrome; Tyrosine

2000
Nitration and inactivation of cytochrome P450BM-3 by peroxynitrite. Stopped-flow measurements prove ferryl intermediates.
    European journal of biochemistry, 2000, Volume: 267, Issue:23

    Topics: Animals; Bacillus; Bacterial Proteins; Binding Sites; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dithiothreitol; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Inhibitory Concentration 50; Iron; Mass Spectrometry; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Molsidomine; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide Donors; Nitrogen; Oxygen; Superoxide Dismutase; Temperature; Time Factors; Tyrosine; Uric Acid

2000
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.
    Free radical biology & medicine, 2001, Jan-01, Volume: 30, Issue:1

    Topics: Blood; Cell Line; Cell Movement; Complement Activation; Deferoxamine; Dithiothreitol; Embryo, Mammalian; Fibroblasts; Fibronectins; Humans; Lung; Molsidomine; Nitrates; Nitric Oxide Donors; Nitrogen; Reactive Oxygen Species; Reducing Agents; Superoxides; Tyrosine; Xanthine Oxidase

2001
Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase, and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells.
    American journal of veterinary research, 2001, Volume: 62, Issue:3

    Topics: Aniline Compounds; Animals; Antioxidants; Blotting, Western; Cattle; Cell Death; Enzyme Inhibitors; Epithelial Cells; Female; Free Radical Scavengers; Histidine; L-Lactate Dehydrogenase; Lipopolysaccharides; Mammary Glands, Animal; Molsidomine; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine

2001
Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro.
    Free radical biology & medicine, 2001, May-01, Volume: 30, Issue:9

    Topics: Animals; Base Sequence; Cell Line; DNA Primers; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Hydrazines; Lung; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; RNA, Messenger; Tyrosine

2001
In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation.
    Blood, 2001, Jun-01, Volume: 97, Issue:11

    Topics: Annexin A5; Apoptosis; Cells, Cultured; Child, Preschool; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; In Situ Nick-End Labeling; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Stromal Cells; Superoxide Dismutase; Superoxides; T-Lymphocytes; Thymus Gland; Tyrosine

2001
Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs.
    Free radical biology & medicine, 2001, Aug-15, Volume: 31, Issue:4

    Topics: Animals; Endothelium, Vascular; Immunoblotting; Immunoenzyme Techniques; Lipopolysaccharides; Liver; Lung; Macrophages; Male; Molsidomine; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Sprague-Dawley; Spleen; Superoxides; Tyrosine

2001
Peroxynitrite causes endothelial cell monolayer barrier dysfunction.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:3

    Topics: Actins; Animals; beta Catenin; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Pulmonary Artery; Reactive Oxygen Species; Superoxide Dismutase; Swine; Trans-Activators; Tyrosine

2001
Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants.
    Molecular pharmacology, 2001, Volume: 60, Issue:4

    Topics: Acetates; Acetylcholine; Animals; Antioxidants; Biological Transport; Carbon Radioisotopes; Choline; Choline O-Acetyltransferase; Drug Interactions; Molsidomine; Nitrates; Oxidants; Reducing Agents; Torpedo; Tyrosine; Uric Acid

2001
SIN-1-induced cytotoxicity in mixed cortical cell culture: peroxynitrite-dependent and -independent induction of excitotoxic cell death.
    Journal of neurochemistry, 2001, Volume: 79, Issue:2

    Topics: Animals; Astrocytes; Catalase; Cell Death; Cells, Cultured; Cerebral Cortex; Free Radical Scavengers; Mice; Molsidomine; Neurons; Neurotoxins; Peroxynitrous Acid; Superoxide Dismutase; Tyrosine

2001
Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Carrier Proteins; Cell Line; Diabetes Mellitus; Dose-Response Relationship, Drug; Glutathione; Humans; Immunohistochemistry; Membrane Glycoproteins; Membrane Transport Proteins; Methylene Blue; Mice; Mice, Inbred ICR; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Pigment Epithelium of Eye; Protein Synthesis Inhibitors; Taurine; Time Factors; Tyrosine

2001
Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose.
    Brain research, 2001, Dec-20, Volume: 922, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Astrocytes; Brain; Brain Ischemia; Cell Death; Cytokines; Dehydroepiandrosterone; Enzyme Inhibitors; Free Radical Scavengers; Glioma; Glucose; Herbicides; Humans; Interferon-gamma; Lipopolysaccharides; Metalloporphyrins; Molsidomine; Neurons; Nitric Oxide; Oxidative Stress; Paraquat; Peroxynitrous Acid; Superoxide Dismutase; Tumor Cells, Cultured; Tyrosine

2001
Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells.
    Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:1

    Topics: Adenosine Triphosphate; Apoptosis; Cell Death; Cysteine Proteinase Inhibitors; Dopamine; Electron Transport Complex I; Humans; Mitochondria; Molsidomine; NADH, NADPH Oxidoreductases; Nitric Oxide Donors; Oligopeptides; Peroxynitrous Acid; Subcellular Fractions; Tumor Cells, Cultured; Tyrosine

2002
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:1

    Topics: Acetylcholine; Animals; Bronchi; Bronchial Hyperreactivity; Inflammation; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molsidomine; Peroxynitrous Acid; Trachea; Tyrosine

2002
Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea.
    Journal of agricultural and food chemistry, 2002, Oct-09, Volume: 50, Issue:21

    Topics: Brassica; Coumaric Acids; Free Radical Scavengers; Lipid Peroxidation; Lipoproteins, LDL; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Serum Albumin, Bovine; Superoxides; Tyrosine

2002
Comparison of uric acid and ascorbic acid in protection against EAE.
    Free radical biology & medicine, 2002, Nov-15, Volume: 33, Issue:10

    Topics: Albumins; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Cell Line; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Immunohistochemistry; Iron; Lipid Peroxidation; Mice; Molsidomine; Myelin Sheath; Nitric Oxide; Oxygen; Peroxynitrous Acid; Rhodamines; Time Factors; Tyrosine; Uric Acid

2002
Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin.
    Journal of neuroscience research, 2003, Jan-15, Volume: 71, Issue:2

    Topics: 2,4-Dinitrophenol; Animals; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Immunohistochemistry; Male; Metalloporphyrins; Microdialysis; Molsidomine; Neurons; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Time Factors; Tyrosine

2003
Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide.
    American journal of respiratory cell and molecular biology, 2003, Volume: 28, Issue:6

    Topics: Animals; Catalase; Cell Cycle; Cells, Cultured; Cyclin D1; Epithelial Cells; Fluoresceins; Gene Expression Regulation; Hydrogen Peroxide; Mice; Molsidomine; Nitric Oxide Donors; Nitrogen Dioxide; Oxidants; Pulmonary Alveoli; Signal Transduction; Superoxide Dismutase; Transcription Factor AP-1; Tyrosine

2003
Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses.
    Journal of leukocyte biology, 2003, Volume: 73, Issue:3

    Topics: Actins; Chemotaxis; Dimerization; Dose-Response Relationship, Drug; Humans; Molsidomine; Neutrophil Activation; Neutrophils; Nitric Oxide Donors; Peroxynitrous Acid; Phagocytosis; Reactive Oxygen Species; Respiratory Burst; Tyrosine

2003
Protective activity of (-)-epicatechin 3-O-gallate against peroxynitrite-mediated renal damage.
    Free radical research, 2003, Volume: 37, Issue:5

    Topics: Animals; Antioxidants; Caspases; Catechin; Cell Cycle; Cell Line; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione; Glutathione Peroxidase; Kidney; Lipid Peroxides; Lipopolysaccharides; LLC-PK1 Cells; Male; Molsidomine; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Rhodamines; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine

2003
Effects of oxygen on the reactivity of nitrogen oxide species including peroxynitrite.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:1

    Topics: Anaerobiosis; Electron Spin Resonance Spectroscopy; Glutathione; Molsidomine; Morpholines; Nitric Oxide; Nitrogen Oxides; Nitrosamines; Nitrous Oxide; Oxygen; Peroxynitrous Acid; S-Nitrosoglutathione; Solutions; Tyrosine

2004
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
    British journal of pharmacology, 2004, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine

2004
Nitric oxide and superoxide impair human placental amino acid uptake and increase Na+ permeability: implications for fetal growth.
    Free radical biology & medicine, 2004, Feb-01, Volume: 36, Issue:3

    Topics: Amino Acids; Biological Transport; Female; Fetal Growth Retardation; Free Radicals; Humans; Infant, Newborn; Microvilli; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Placenta; Pregnancy; Sodium; Subcellular Fractions; Superoxides; Time Factors; Trophoblasts; Tyrosine

2004
Peroxynitrite decreases hemostasis in human plasma in vitro.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:1

    Topics: Blood Coagulation Factors; Blotting, Western; Coagulants; Dose-Response Relationship, Drug; Factor X; Hemostasis; Humans; In Vitro Techniques; Molsidomine; Nitric Oxide Donors; Partial Thromboplastin Time; Peroxynitrous Acid; Plasma; Protein C; Prothrombin Time; Superoxide Dismutase; Thrombelastography; Tyrosine

2004
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:12

    Topics: Animals; Aorta; Apolipoproteins E; Apoptosis; Atherosclerosis; Calcium; Cells, Cultured; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endothelium, Vascular; Female; Homeostasis; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Peroxynitrous Acid; Superoxides; Tyrosine; Umbilical Veins

2005
Peroxynitrite induces F-actin depolymerization and blockade of myosin ATPase stimulation.
    Biochemical and biophysical research communications, 2006, Mar-31, Volume: 342, Issue:1

    Topics: Actins; Animals; Calorimetry, Differential Scanning; Enzyme Activation; Molsidomine; Myosins; Oxidation-Reduction; Peroxynitrous Acid; Protein Denaturation; Protein Folding; Rabbits; Temperature; Tyrosine

2006
Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite.
    Biochemistry, 2006, Mar-21, Volume: 45, Issue:11

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Catalysis; Cysteine; Dose-Response Relationship, Drug; Enzyme Stability; Magnesium; Molsidomine; Myosin Subfragments; Oxidation-Reduction; Peroxynitrous Acid; Protein Folding; Rabbits; Skeletal Muscle Myosins; Temperature; Time Factors; Tyrosine

2006
Peroxynitrite generation and tyrosine nitration in defense responses in tobacco BY-2 cells.
    Plant & cell physiology, 2006, Volume: 47, Issue:6

    Topics: Algal Proteins; Aniline Compounds; Antibodies, Anti-Idiotypic; Cells, Cultured; Cyclic GMP; Fluoresceins; Fungal Proteins; Molsidomine; Nicotiana; Nitric Oxide; Peroxynitrous Acid; Phytophthora; Proteins; Reactive Oxygen Species; Superoxides; Tyrosine; Uric Acid

2006
Effect of lycopene and beta-carotene on peroxynitrite-mediated cellular modifications.
    Toxicology and applied pharmacology, 2006, Sep-15, Volume: 215, Issue:3

    Topics: Animals; Antioxidants; beta Carotene; Carotenoids; Cell Line; Cell Survival; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Lycopene; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Tyrosine

2006
Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling.
    Biochemical and biophysical research communications, 2006, Sep-08, Volume: 347, Issue:4

    Topics: Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Hesperidin; Humans; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Signal Transduction; Tyrosine

2006
Thioredoxin reduces post-ischemic myocardial apoptosis by reducing oxidative/nitrative stress.
    British journal of pharmacology, 2006, Volume: 149, Issue:3

    Topics: Animals; Apoptosis; Male; Mice; Molsidomine; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Superoxides; Thioredoxins; Tyrosine

2006
Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: identification of SULT1A3 as the enzyme responsible.
    The Biochemical journal, 2007, Jan-15, Volume: 401, Issue:2

    Topics: Arylsulfotransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Dopamine; Humans; Kinetics; Molsidomine; Sulfotransferases; Tyrosine

2007
Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers.
    Journal of neuroscience research, 2007, Aug-01, Volume: 85, Issue:10

    Topics: Aldehydes; Animals; Cell Respiration; Cerebral Cortex; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Transport Complex I; Free Radical Scavengers; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitochondria; Molsidomine; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Penicillamine; Peroxynitrous Acid; Protein Carbonylation; Spin Labels; Tyrosine

2007
The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord.
    Neuroscience, 2008, Sep-22, Volume: 156, Issue:1

    Topics: Action Potentials; Animals; Axons; Cell Membrane; Dose-Response Relationship, Drug; Extracellular Fluid; Female; Guinea Pigs; Molsidomine; Nerve Degeneration; Neural Conduction; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Peroxynitrous Acid; Sodium Channels; Spinal Cord; Spinal Cord Injuries; Tyrosine

2008
LDL protein nitration: implication for LDL protein unfolding.
    Archives of biochemistry and biophysics, 2008, Nov-01, Volume: 479, Issue:1

    Topics: Animals; Aorta; Apolipoprotein B-100; Cattle; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Models, Chemical; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Protein Conformation; Protein Denaturation; Protein Processing, Post-Translational; Protein Structure, Secondary; Proteins; Reproducibility of Results; Tyrosine

2008
Synthesis and biological activities of neoechinulin A derivatives: new aspects of structure-activity relationships for neoechinulin A.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:12

    Topics: Animals; Antioxidants; Brain Chemistry; Cell Survival; Indicators and Reagents; Indole Alkaloids; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Molsidomine; Nitrates; PC12 Cells; Peroxynitrous Acid; Piperazines; Protective Agents; Rats; Structure-Activity Relationship; Tyrosine

2008
Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:5

    Topics: Amino Acid Sequence; Animals; Bronchoalveolar Lavage Fluid; Humans; Mice; Molsidomine; Nitrogen Dioxide; Peroxynitrous Acid; Protein Structure, Quaternary; Protein Structure, Tertiary; Pulmonary Surfactant-Associated Protein D; Rats; Recombinant Proteins; Tandem Mass Spectrometry; Tyrosine

2009
Peroxynitrite induces gene expression in intervertebral disc cells.
    Spine, 2009, May-15, Volume: 34, Issue:11

    Topics: Active Transport, Cell Nucleus; Adolescent; Adult; Cell Nucleus; Cells, Cultured; Female; Gene Expression; Humans; Immunohistochemistry; Interleukin-10; Interleukin-1beta; Interleukin-6; Interleukin-8; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine

2009
The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion.
    European journal of pharmacology, 2010, Feb-10, Volume: 627, Issue:1-3

    Topics: Blood Platelets; Blood Proteins; Cell Adhesion; Enzyme Inhibitors; Fibrinogen; Free Radical Scavengers; Guanylate Cyclase; Humans; Molsidomine; Nitrates; Peroxynitrous Acid; Solubility; Superoxides; Thrombin; Tyrosine

2010
Protective effects of flavonoids against oxidative stress induced by simulated microgravity in SH-SY5Y cells.
    Neurochemical research, 2010, Volume: 35, Issue:9

    Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Flavonols; Humans; Hydrogen Peroxide; Luteolin; Molecular Structure; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Oxidants; Oxidative Stress; Quercetin; Reactive Oxygen Species; Tyrosine; Weightlessness

2010
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.
    Free radical biology & medicine, 2011, Jun-01, Volume: 50, Issue:11

    Topics: Acetophenones; Allopurinol; Animals; Arrhythmias, Cardiac; Coronary Vessels; Ethidium; Male; Molsidomine; Myocardial Infarction; Myocardium; NADPH Oxidases; Nerve Growth Factor; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Sympathetic Nervous System; Tyrosine; Xanthine Oxidase

2011
Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:1

    Topics: Animals; Azepines; Biomarkers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; Male; Mesenteric Arteries; Molsidomine; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phosphodiesterase 4 Inhibitors; Rats; Rats, Sprague-Dawley; Tyrosine; Vascular System Injuries

2011
High glucose induced rat aorta vascular smooth muscle cell oxidative injury: involvement of protein tyrosine nitration.
    Journal of physiology and biochemistry, 2011, Volume: 67, Issue:4

    Topics: Animals; Aorta; Cell Survival; Glucose; Glucose Oxidase; Glutathione; Hemin; Lipid Peroxidation; Male; Molsidomine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Primary Cell Culture; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine

2011
Neuroprotective effects of Cyperus rotundus on SIN-1 induced nitric oxide generation and protein nitration: ameliorative effect against apoptosis mediated neuronal cell damage.
    Neurotoxicology, 2013, Volume: 34

    Topics: Apoptosis; Blotting, Western; Caspase 3; Catalase; Cell Death; Cell Line, Tumor; Cyperus; Cytoprotection; DNA Damage; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Humans; Lipid Peroxidation; Molsidomine; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rhizome; Superoxide Dismutase; Tyrosine

2013
Posttranslational nitro-glycative modifications of albumin in Alzheimer's disease: implications in cytotoxicity and amyloid-β peptide aggregation.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 40, Issue:3

    Topics: Aged; Albumins; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Female; Glycosylation; Humans; Male; Molsidomine; Neurons; Peptide Fragments; Protein Aggregates; Protein Processing, Post-Translational; tau Proteins; Trypsin; Tyrosine

2014
Effect of oxidative stress on the expression of thin filament-associated proteins in gastric smooth muscle cells.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:1

    Topics: Animals; Gastrointestinal Motility; Gene Expression Regulation; Male; Microfilament Proteins; Molsidomine; Muscle, Smooth; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stomach; Tyrosine

2014
Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Mar-15, Volume: 308, Issue:6

    Topics: Animals; Calcium Chloride; CHO Cells; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Ileum; KATP Channels; Mice; Molsidomine; Muscle Contraction; Muscle, Smooth; Mutation; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction; Sulfides; Sulfonylurea Receptors; Transfection; Tyrosine

2015