linoleic-acid-hydroperoxide has been researched along with 2-methyl-6-(4-methoxyphenyl)-3-7-dihydroimidazo(1-2-alpha)pyrazin-3-one* in 1 studies
1 other study(ies) available for linoleic-acid-hydroperoxide and 2-methyl-6-(4-methoxyphenyl)-3-7-dihydroimidazo(1-2-alpha)pyrazin-3-one
| Article | Year |
|---|---|
Mechanism for the generation of superoxide anion and singlet oxygen during heme compound-catalyzed linoleic acid hydroperoxide decomposition.
Heme compound, hematin or cytochrome c, catalyzes the decomposition of 13-hydroperoxy linoleic acid yielding both O2- and 1O2 under aerobic conditions. No 1O2 is produced when hydrogen peroxide and cumene hydroperoxide are used as substrates. In these experiments, both O2- and 1O2 could be precisely detected by a chemiluminescence method using a cypridina luciferin analog, 2-methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin++ +-3-one, as a chemiluminescence probe, in the absence and presence of Cu-Zn superoxide dismutase in catalytic amounts. The reduction and oxidation cycle of ferric heme compound and the bimolecular reaction of peroxyl radicals are plausible reaction mechanisms for O2- and 1O2 production, respectively, in the systems studied. Topics: Catalysis; Heme; Imidazoles; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Luminescent Measurements; Oxidation-Reduction; Oxygen; Pyrazines; Singlet Oxygen; Superoxides | 1991 |