linezolid has been researched along with acetohydroxamic-acid* in 1 studies
1 other study(ies) available for linezolid and acetohydroxamic-acid
Article | Year |
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Synthesis and antibacterial activity of novel oxazolidinones bearing N-hydroxyacetamidine substituent.
Novel oxazolidinone antibacterials containing N-hydroxyacetamidine moiety are synthesized with the diversity at C-5 terminus. These compounds have been evaluated against a panel of clinically relevant gram-positive and gram-negative pathogens. Most of the analogs in this series displayed activity superior to Linezolid and in vivo efficacies of selected oxazolidinones are also disclosed herein. Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hydroxamic Acids; Mice; Microbial Sensitivity Tests; Molecular Conformation; Oxazolidinones; Stereoisomerism | 2006 |