Page last updated: 2024-09-05

limonin and rutecarpine

limonin has been researched along with rutecarpine in 9 studies

Compound Research Comparison

Studies
(limonin)
Trials
(limonin)
Recent Studies (post-2010)
(limonin)
Studies
(rutecarpine)
Trials
(rutecarpine)
Recent Studies (post-2010) (rutecarpine)
15901062351125

Protein Interaction Comparison

ProteinTaxonomylimonin (IC50)rutecarpine (IC50)
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.23
Cytochrome P450 1A1Homo sapiens (human)0.26
Cytochrome P450 1A2Homo sapiens (human)0.022
Prostaglandin G/H synthase 1Homo sapiens (human)8.7
Prostaglandin G/H synthase 2Homo sapiens (human)0.29
Cytochrome P450 1B1Homo sapiens (human)0.055

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Iinuma, M; Kubo, M; Matsuda, H; Tanaka, T; Wu, JX1
Hiratsuka, A; Iwata, H; Kadota, S; Tezuka, Y; Watabe, T1
Cai, Z; Gong, X; Li, Z; Zhao, Y; Zhou, C; Zhou, X1
Chen, Y; Huang, Z; Liu, Y; Wu, Y; Yi, J1
Chen, Y; Huang, Z; Liu, Y; Tang, X; Yi, J; Zhao, J1
Gong, M; Li, J; Li, Z; Lu, X; Pan, X; Shang, Y; Wang, M; Wu, Y; Xu, Y; Zhai, Y1
Chen, Z; Liu, Y; Mao, Z; Zhou, W1

Reviews

1 review(s) available for limonin and rutecarpine

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005

Other Studies

8 other study(ies) available for limonin and rutecarpine

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Antinociceptive activities of 70% methanol extract of evodiae fructus (fruit of Evodia rutaecarpa var. bodinieri) and its alkaloidal components.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:3

    Topics: Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; China; Chromatography, High Pressure Liquid; Indole Alkaloids; Limonins; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Plant Extracts; Plants, Medicinal; Quinazolines; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Triterpenes; Vasodilator Agents

1997
Mechanism-based inactivation of human liver microsomal CYP3A4 by rutaecarpine and limonin from Evodia fruit extract.
    Drug metabolism and pharmacokinetics, 2005, Volume: 20, Issue:1

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Evodia; Fruit; Humans; Indole Alkaloids; Kinetics; Limonins; Magnetic Resonance Spectroscopy; Microsomes, Liver; Plant Extracts; Quinazolines

2005
Quality evaluation of Evodia rutaecarpa (Juss.) Benth by high performance liquid chromatography with photodiode-array detection.
    Journal of pharmaceutical and biomedical analysis, 2008, Dec-01, Volume: 48, Issue:4

    Topics: Calibration; Chromatography, High Pressure Liquid; Cluster Analysis; Drug Stability; Evodia; Indole Alkaloids; Limonins; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Principal Component Analysis; Quality Control; Quercetin; Quinazolines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2008
[Optimization of a HPLC determination method for Evodia rutaecarpa].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:4

    Topics: Chromatography, High Pressure Liquid; Evodia; Indole Alkaloids; Limonins; Plant Extracts; Quinazolines

2011
Simultaneous determination of six bioactive compounds in Evodiae Fructus by high-performance liquid chromatography with diode array detection.
    Journal of chromatographic science, 2014, Volume: 52, Issue:2

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Evodia; Fruit; Indole Alkaloids; Limonins; Plant Extracts; Quinazolines; Reproducibility of Results; Triterpenes

2014
Identification of active ingredients in Wuzhuyu decoction improving migraine in mice by spectral efficiency association.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Animals; Brain; China; Drugs, Chinese Herbal; Ginsenosides; Humans; Indole Alkaloids; Limonins; Medicine, Chinese Traditional; Mice; Migraine Disorders; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Quinazolines; Reserpine; Serotonin

2015
Analysis of Evodiae Fructus by capillary electrochromatography-mass spectrometry with methyl-vinylimidazole functionalized organic polymer monolilth as stationary phases.
    Journal of chromatography. A, 2019, Sep-27, Volume: 1602

    Topics: Acetonitriles; Ammonia; Calibration; Capillary Electrochromatography; Drugs, Chinese Herbal; Electrolytes; Evodia; Fruit; Hydrogen-Ion Concentration; Imidazoles; Indole Alkaloids; Limit of Detection; Limonins; Mass Spectrometry; Polymers; Quinazolines; Reference Standards; Reproducibility of Results

2019