lignans has been researched along with phenanthroindolizidine* in 1 studies
1 other study(ies) available for lignans and phenanthroindolizidine
Article | Year |
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Hispidacine, an unusual 8,4'-oxyneolignan-alkaloid with vasorelaxant activity, and hispiloscine, an antiproliferative phenanthroindolizidine alkaloid, from Ficus hispida Linn.
Hispidacine, an 8,4'-oxyneolignan featuring incorporation of an unusual 2-hydroxyethylamine moiety at C-7, and hispiloscine, a phenanthroindolizidine alkaloid, were isolated from the stem-bark and leaves of the Malaysian Ficus hispida Linn. Their structures were established by spectroscopic analysis. Hispidacine induced a moderate vasorelaxant activity in rat isolated aorta, while hispiloscine showed appreciable antiproliferative activities against MDA-MB-231, MCF-7, A549, HCT-116 and MRC-5 cell lines. Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Aorta; Cell Line, Tumor; Ficus; Humans; Indolizidines; Indolizines; Lignans; Male; Molecular Structure; Phenanthrolines; Plant Bark; Plant Leaves; Rats, Sprague-Dawley; Vasodilator Agents | 2015 |