lignans and pentaerythritol-tetra(3-mercaptopropionate)

Magnolol, a neolignan natural product with antioxidant properties, contains inherent, orthogonal, phenolic, and alkenyl reactive groups that were used in both direct thermoset synthesis, as well as the stepwise synthesis of a small library of monomers, followed by transformation into thermoset materials. Each monomer from the small library was prepared via a single step functionalization reaction of the phenolic groups of magnolol. Thermoset materials were realized through solvent-free, thiol-ene reactions, and the resulting cross-linked materials were each comprised of thioether and ester linkages, with one retaining the hydrophilic phenols from magnolol, another having the phenols protected as an acetonide, and two others incorporating the phenols into additional cross-linking sites via hydrolytically labile carbonates or stable ether linkages. With this diversity of chemical compositions and structures, the thermosets displayed a range of thermomechanical properties including glass transition temperatures, T

Topics: 3-Mercaptopropionic Acid; Animals; Antioxidants; Biodegradable Plastics; Biphenyl Compounds; Cattle; Cells, Cultured; Endothelial Cells; Lignans; Phenols; Propylene Glycols; Stimuli Responsive Polymers; Stress, Mechanical; Temperature