lignans and indole-3-carbaldehyde

To study the chemical constituents of the whole plant of Sphagneticola trilobata.. The compounds were isolated and purified by column chromatography and their structures were determined by spectroscopic techniques.. Three lignans, two indolics and two phenolic glycosides were isolated from the whole plant of Sphagneticola trilobata and identified as syringaresinol-4-O-β-D-glucopyranoside(1), pinoresinol-4-sulfate(2), pinoresinol-4-O-β-D-glucopyranoside(3), 1H-indole-3-carboxylic acid (4), 1H-indole-3-carbaldehyde(5), 2,6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (6), and 3,5-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (7).. Compounds 1 - 7 are isolated from the genus Wedelia for the first time. Compound 4 demonstrates significant inhibitory activity against α-glucosidase.

Topics: Asteraceae; Glucosides; Glycosides; Indoles; Lignans; Phenols; Plants, Medicinal