lignans and chamaejasmin

lignans has been researched along with chamaejasmin* in 1 studies

Other Studies

1 other study(ies) available for lignans and chamaejasmin

Article	Year
Chemical constituents and biological activities from roots of Enkleia siamensis. Natural product research, 2014, Volume: 28, Issue:4 Chemical investigation from roots of Enkleia siamensis (Kurz) Nervling resulted in the isolation of 10 compounds. Their structures were established on the basis of 1D and 2D NMR spectroscopic data as linobiflavonoid (1), chamaejasmin (2), 7-O-β-D-glucopyranosylchamaejasmin (3), ormocarpin (4), (-)-wikstromol (5), matairesinol (6), (+)-lariciresinol (7), umbelliferone (8), daphnoretin (9) and carthamidin (10). Compounds 2 and 8 showed cytotoxicity against KB, MCF-7 and NCI-H187 cancer cell lines. Compounds 1, 2 and 5 showed weak minimum inhibitory requirements to acetylcholinesterase with values ranging from 50 to 1000 ng. In addition, compound 2 exhibited antimalarial activity against Plasmodium falciparum with an IC50 value of 2.32 μg/mL. Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Biflavonoids; Cholinesterase Inhibitors; Coumarins; Drug Screening Assays, Antitumor; Flavonoids; Furans; Humans; KB Cells; Lignans; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plasmodium falciparum; Thailand; Thymelaeaceae	2014

Article

Year

Chemical constituents and biological activities from roots of Enkleia siamensis.

Natural product research, 2014, Volume: 28, Issue:4

Chemical investigation from roots of Enkleia siamensis (Kurz) Nervling resulted in the isolation of 10 compounds. Their structures were established on the basis of 1D and 2D NMR spectroscopic data as linobiflavonoid (1), chamaejasmin (2), 7-O-β-D-glucopyranosylchamaejasmin (3), ormocarpin (4), (-)-wikstromol (5), matairesinol (6), (+)-lariciresinol (7), umbelliferone (8), daphnoretin (9) and carthamidin (10). Compounds 2 and 8 showed cytotoxicity against KB, MCF-7 and NCI-H187 cancer cell lines. Compounds 1, 2 and 5 showed weak minimum inhibitory requirements to acetylcholinesterase with values ranging from 50 to 1000 ng. In addition, compound 2 exhibited antimalarial activity against Plasmodium falciparum with an IC50 value of 2.32 μg/mL.

Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Biflavonoids; Cholinesterase Inhibitors; Coumarins; Drug Screening Assays, Antitumor; Flavonoids; Furans; Humans; KB Cells; Lignans; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plasmodium falciparum; Thailand; Thymelaeaceae

2014