lignans and benzothiophene

lignans has been researched along with benzothiophene* in 1 studies

Other Studies

1 other study(ies) available for lignans and benzothiophene

Article	Year
Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes. Biomolecules, 2020, 07-31, Volume: 10, Issue:8 A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship. It was found that both, the side chain in position five and the substitution pattern of the aryl moiety in position two have a significant influence on the inhibitory activity. Topics: Anti-Inflammatory Agents; Benzofurans; HEK293 Cells; Humans; Lignans; NF-kappa B; Structure-Activity Relationship; Thiophenes	2020

Article

Year

Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes.

Biomolecules, 2020, 07-31, Volume: 10, Issue:8

A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship. It was found that both, the side chain in position five and the substitution pattern of the aryl moiety in position two have a significant influence on the inhibitory activity.

Topics: Anti-Inflammatory Agents; Benzofurans; HEK293 Cells; Humans; Lignans; NF-kappa B; Structure-Activity Relationship; Thiophenes

2020