lignans and benzothiazoline

In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8-O-4' neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2-9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and cytotoxic effects of isolated compounds were evaluated in vitro. The isolated compounds (IC

Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Benzothiazoles; Biphenyl Compounds; Bupleurum; Cell Line, Tumor; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Inhibitory Concentration 50; Lignans; MCF-7 Cells; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Picrates; Plant Roots