lidocaine and warfarin

lidocaine has been researched along with warfarin in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (21.74)	18.7374
1990's	9 (19.57)	18.2507
2000's	17 (36.96)	29.6817
2010's	10 (21.74)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Caron, G; Ermondi, G	1
Jolivette, LJ; Ward, KW	1
Carrupt, PA; Martel, S; Ottaviani, G	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Conradi, R; Lee, PH; Shanmugasundaram, V	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Blaschke, TF; Esquivel, M; Meffin, PJ; Snidow, GH	1
Rose, SD	1
Feely, J; Grimm, T	1
Routledge, PA	1
Raisfeld, IH	1
Chiou, WL; Moorhatch, P	1
Blount, AW; Miller, DS	1
Katz, J; Levine, DA; Rosen, N	1
Greene, WL; Levinson, MJ; Self, TH	1
Feely, J	1
D'Arcy, PF	1
Arvela, P; Bäckstrom, M; Pelkonen, O; Rautio, A; Sotaniemi, EA	1
Farid, R; Feely, J; Ghalighi, MR; Hosseine, SJ	1
Arvela, P; Mustajoki, P; Mustajoki, S; Pelkonen, O; Rautio, A	1
Barry, MG; Collins, WC; Cullen, MJ; Feely, J; O'Byrne, S; O'Connor, P	1
Groothuis, GM; Meijer, DK; Merema, M; Olinga, P; Slooff, MJ	1
de Jong, KP; Groothuis, GM; Hof, IH; Meijer, DK; Merema, M; Olinga, P; Slooff, MJ	1
De Jager, MH; De Jong, KP; Groothuis, GM; Hof, IH; Meijer, DK; Merema, MT; Olinga, P; Slooff, MJ	1
Ottiger, C; Wunderli-Allenspach, H	1
Evans, IL; Gibbons, AJ; Price, G; Sayers, MS; Snooks, H; Sugar, AW	1
De Jager, MH; De Kanter, R; Draaisma, AL; Groothuis, GM; Jurva, JU; Meijer, DK; Olinga, P	1
Atarashi, H; Fukunami, M; Inoue, H; Kumagai, K; Okishige, K	1
Deryabina, MA; Hansen, SH; Jensen, H	1
Groothuis, GM; Merema, MT; van Midwoud, PM; Verpoorte, E	1

Reviews

4 review(s) available for lidocaine and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The Smith Kline & French lecture 1987. Clinical pharmacology and the art of bespoke prescribing. British journal of clinical pharmacology, 1988, Volume: 26, Issue:4 Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Prescriptions; Heparin; Humans; Lidocaine; Warfarin	1988
Clinical pharmacology of drug interactions. Annual review of medicine, 1973, Volume: 24 Topics: Antihypertensive Agents; Blood Coagulation Disorders; Cardiovascular Diseases; Coumarins; Drug Interactions; Epilepsy; Heparin; Humans; Hypertension; Lidocaine; Mental Disorders; Pharmaceutical Preparations; Phenothiazines; Phenytoin; Procainamide; Salicylates	1973
Interaction of cimetidine with other drugs. Southern medical journal, 1983, Volume: 76, Issue:6 Topics: Aged; Chlormethiazole; Cimetidine; Diazepam; Drug Interactions; Guanidines; Humans; Lidocaine; Liver; Liver Circulation; Phenytoin; Propranolol; Tissue Distribution; Warfarin	1983

Trials

3 trial(s) available for lidocaine and warfarin

Article	Year
Prophylaxis of thromboembolic disease. The Medical clinics of North America, 1979, Volume: 63, Issue:6 Topics: Abdomen; Aspirin; Clinical Trials as Topic; Dextrans; Double-Blind Method; Early Ambulation; Hemorrhage; Heparin; Humans; Injections, Subcutaneous; Lidocaine; Male; Orthopedics; Postoperative Complications; Posture; Prostate; Thoracic Surgery; Thromboembolism; Warfarin	1979
Can warfarin be continued during dental extraction? Results of a randomized controlled trial. The British journal of oral & maxillofacial surgery, 2002, Volume: 40, Issue:3 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthetics, Local; Anticoagulants; Chi-Square Distribution; Confidence Intervals; Female; Follow-Up Studies; Hemostasis, Surgical; Humans; International Normalized Ratio; Lidocaine; Male; Middle Aged; Oral Hemorrhage; Postoperative Hemorrhage; Risk Factors; Statistics as Topic; Tooth Extraction; Warfarin	2002
Pharmacological conversion of persistent atrial fibrillation into sinus rhythm with oral pilsicainide: pilsicainide suppression trial for persistent atrial fibrillation II. Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:6 Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Contraindications; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Recovery of Function; Remission Induction; Thrombosis; Warfarin	2006

Other Studies

39 other study(ies) available for lidocaine and warfarin

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Effect of phenobarbitone on the disposition of lignocaine and warfarin in the dog. The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:12 Topics: Animals; Biological Availability; Dogs; Drug Interactions; Lidocaine; Liver Circulation; Phenobarbital; Time Factors; Warfarin	1978
A comparison of drug protein binding and alpha 1-acid glycoprotein concentration in Chinese and Caucasians. British journal of clinical pharmacology, 1991, Volume: 31, Issue:5 Topics: Adult; Asian People; Blood Proteins; Female; Humans; Lidocaine; Male; Orosomucoid; Pharmaceutical Preparations; Protein Binding; Warfarin; White People	1991
Interactions between drugs and plastic intravenous fluid bags. I. Sorption studies on 17 drugs. American journal of hospital pharmacy, 1974, Volume: 31, Issue:1 Topics: Absorption; Drug Compounding; Drug Interactions; Drug Packaging; Glucose; Hydrocortisone; Hydrogen-Ion Concentration; Lidocaine; Methohexital; Pentobarbital; Plastics; Sodium Chloride; Solutions; Spectrophotometry; Temperature; Time Factors; Tubocurarine; Vitamins; Warfarin	1974
Quinidine-induced recurrent ventricular fibrillation: (quinidine syncope) treated with transvenous pacemaker. Southern medical journal, 1971, Volume: 64, Issue:5 Topics: Adult; Atrial Fibrillation; Atropine; Blood Cell Count; Chlorpromazine; Coumarins; Creatine Kinase; Digitalis Glycosides; Diuretics; Electric Countershock; Electrocardiography; Female; Heart Valve Prosthesis; Humans; L-Lactate Dehydrogenase; Lactates; Lidocaine; Mitral Valve Stenosis; Pacemaker, Artificial; Paranoid Disorders; Pneumonia; Potassium Chloride; Quinidine; Rheumatic Heart Disease; Syncope; Ventricular Fibrillation	1971
Anesthesia for patients with prosthetic heart valves. JAMA, 1967, Dec-04, Volume: 202, Issue:10 Topics: Anesthesia; Halothane; Heart Valve Prosthesis; Humans; Lidocaine; Meperidine; Middle Aged; Succinylcholine; Thiopental; Tolbutamide; Tubocurarine; Warfarin	1967
Cimetidine drug interactions. The Journal of family practice, 1983, Volume: 16, Issue:6 Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Anti-Arrhythmia Agents; Anticonvulsants; Benzodiazepines; Cimetidine; Drug Interactions; Guanidines; Humans; Lidocaine; Peptic Ulcer; Warfarin	1983
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients. British journal of clinical pharmacology, 1995, Volume: 39, Issue:1 Topics: Administration, Oral; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Capsules; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Epilepsy; Female; Humans; Injections, Intravenous; Isoenzymes; Kidney Diseases; Kidney Function Tests; Lidocaine; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Middle Aged; Mixed Function Oxygenases; Peptide Fragments; Procollagen; Umbelliferones	1995
Interethnic differences in drug protein binding and alpha 1 acid glycoprotein concentration. Irish journal of medical science, 1995, Volume: 164, Issue:1 Topics: Adolescent; Adult; Cross-Cultural Comparison; Ethnicity; Female; Humans; Iran; Ireland; Lidocaine; Male; Orosomucoid; Protein Binding; Reference Values; Warfarin	1995
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:1 Topics: Adult; Arginine; Caffeine; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Heme; Humans; Isoenzymes; Lidocaine; Male; Middle Aged; Porphyrias, Hepatic; Reference Values	1994
Plasma protein binding of lidocaine and warfarin in insulin-dependent and non-insulin-dependent diabetes mellitus. Clinical pharmacokinetics, 1993, Volume: 24, Issue:2 Topics: Adolescent; Adult; Aged; Blood Proteins; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dialysis; Female; Glycated Hemoglobin; Humans; Lidocaine; Male; Middle Aged; Protein Binding; Warfarin	1993
Influence of 48 hours of cold storage in University of Wisconsin organ preservation solution on metabolic capacity of rat hepatocytes. Journal of hepatology, 1997, Volume: 27, Issue:4 Topics: Animals; Coumarins; Cryopreservation; Lidocaine; Liver; Male; Organ Preservation Solutions; Rats; Rats, Wistar; Time Factors; Universities; Wisconsin	1997
Effect of human liver source on the functionality of isolated hepatocytes and liver slices. Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:1 Topics: Adenosine Triphosphate; Adolescent; Adult; Age Factors; Aged; Cell Survival; Child; Child, Preschool; Coumarins; Hepatectomy; Humans; Lidocaine; Liver; Liver Transplantation; Middle Aged; Organ Preservation Solutions; Potassium; Taurocholic Acid; Testosterone	1998
Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver. Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:4 Topics: Animals; Cold Temperature; Coumarins; Cryopreservation; Hot Temperature; Humans; In Vitro Techniques; Ischemia; Lidocaine; Liver; Macaca fascicularis; Organ Preservation; Testosterone	1998
Immobilized artificial membrane (IAM)-HPLC for partition studies of neutral and ionized acids and bases in comparison with the liposomal partition system. Pharmaceutical research, 1999, Volume: 16, Issue:5 Topics: Alkalies; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anticoagulants; Buffers; Chromatography, High Pressure Liquid; Diazepam; Hydrogen-Ion Concentration; Ions; Kinetics; Lidocaine; Liposomes; Membranes, Artificial; Phosphatidylcholines; Propranolol; Salicylates; Solvents; Temperature; Thermodynamics; Vasodilator Agents; Warfarin	1999
Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices. Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:5 Topics: Adenosine Triphosphate; Animals; Biotransformation; Coumarins; Humans; In Vitro Techniques; Intestinal Mucosa; Kidney; Lidocaine; Liver; Lung; Male; Pharmaceutical Preparations; Rats; Rats, Wistar; Testosterone; Umbelliferones	2002
Molecular interactions in lipophilic environments studied by electrochemistry at interfaces between immiscible electrolyte solutions. Analytical chemistry, 2008, Jan-01, Volume: 80, Issue:1 Topics: Buffers; Cholesterol; Diflunisal; Electrochemistry; Electrolytes; Hydrophobic and Hydrophilic Interactions; Lidocaine; Ligands; Prilocaine; Propranolol; Solutions; Warfarin	2008
A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices. Lab on a chip, 2010, Oct-21, Volume: 10, Issue:20 Topics: Animals; Coumarins; Equipment Design; Equipment Failure Analysis; Flow Injection Analysis; Intestinal Mucosa; Lidocaine; Liver; Male; Microfluidic Analytical Techniques; Organ Culture Techniques; Rats; Rats, Wistar	2010