lidocaine and saxitoxin

lidocaine has been researched along with saxitoxin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's4 (22.22)18.2507
2000's5 (27.78)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ritchie, JM3
Takman, BH1
Narahashi, T; Roy, ML1
Abe, T; Satake, M; Yanagawa, Y1
Henderson, R; Ritchie, JM; Strichartz, GR1
Covino, BG; Gissen, AJ; Gregus, J1
Hanck, DA; Makielski, JC; Sheets, MF2
Goldstein, S; Lesch, M; Maltsev, VA; Sabbah, HN; Tanimura, M; Undrovinas, AI1
Maltsev, VA; Sabbah, HN; Undrovinas, AI1
Fozzard, HA; Glaaser, IW; Sunami, A1
Kobayashi, H; Minami, S; Saitoh, T; Shiraishi, S; Takasaki, M; Wada, A; Yanagita, T; Yokoo, H1
Cummins, TR; Dib-Hajj, SD; Herzog, RI; Leffler, A; Waxman, SG1
Chartier, D; Leblanc, N; Nattel, S; Ruben, PC; Sun, H; Varela, D; Zamponi, GW1
Carneiro, RF; Costa, PP; de Oliveira Toyama, D; de Oliveira, SC; de Souza, AJ; Dos Santos Diz Filho, EB; Fonteles, MC; Gomes, VM; Nascimento, NR; Santos, CF; Toyama, MH; Zara, FJ1
Bustamante, T; Del Campo, M; Lagos, N; Muñoz, V; Piron, R; Sánchez, A; Sepúlveda, JM; Simbaina, JC; Torres, C; Valenzuela, C1

Reviews

1 review(s) available for lidocaine and saxitoxin

ArticleYear
A pharmacological approach to the structure of sodium channels in myelinated axons.
    Annual review of neuroscience, 1979, Volume: 2

    Topics: Aconitine; Action Potentials; Anesthetics, Local; Animals; Anura; Batrachotoxins; Benzocaine; Binding Sites; Chemical Phenomena; Chemistry; Decapodiformes; Ion Channels; Lidocaine; Molecular Conformation; Nerve Fibers, Myelinated; Ranvier's Nodes; Saxitoxin; Tetrodotoxin; Veratridine

1979

Trials

1 trial(s) available for lidocaine and saxitoxin

ArticleYear
Evaluation of Neosaxitoxin as a local anesthetic during piglet castration: A potential alternative for Lidocaine.
    Toxicon : official journal of the International Society on Toxinology, 2019, Volume: 164

    Topics: Anesthetics, Local; Animals; Inflammation; Lidocaine; Male; Orchiectomy; Pain; Prospective Studies; Random Allocation; Saxitoxin; Scrotum; Skin Temperature; Sus scrofa

2019

Other Studies

16 other study(ies) available for lidocaine and saxitoxin

ArticleYear
Binding of tetrodotoxin and saxitoxin to sodium channels.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1975, Jun-10, Volume: 270, Issue:908

    Topics: Animals; Diaphragm; Electrophysiology; Fishes; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Models, Neurological; Muscle Denervation; Nephropidae; Neural Conduction; Neurons; Olfactory Nerve; Ouabain; Rabbits; Saxitoxin; Sodium; Surface Properties; Tetrodotoxin; Thallium; Vagus Nerve; Veratrine

1975
Mechanism of action of local anaesthetic agents and biotoxins.
    British journal of anaesthesia, 1975, Volume: 47 suppl

    Topics: Acetylcholine; Action Potentials; Anesthetics, Local; Animals; Benzocaine; Binding Sites; Binding, Competitive; Calcium; Cell Membrane; Fishes; Humans; Hydrogen-Ion Concentration; Lidocaine; Membrane Potentials; Neural Conduction; Potassium; Procaine; Rabbits; Saxitoxin; Sodium; Structure-Activity Relationship; Surface Properties; Tetrodotoxin; Toxins, Biological

1975
The chemistry of local anaesthetic agents: classification of blocking agents.
    British journal of anaesthesia, 1975, Volume: 47 suppl

    Topics: Anesthetics, Local; Benzocaine; Benzyl Compounds; Binding Sites; Binding, Competitive; Cell Membrane; Lidocaine; Models, Molecular; Neural Conduction; Neurilemma; Phenobarbital; Phenols; Saxitoxin; Sodium; Structure-Activity Relationship; Succinimides; Tetrodotoxin

1975
Differential properties of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:6

    Topics: Animals; Cations, Divalent; Dose-Response Relationship, Drug; Drug Resistance; Electrophysiology; Ganglia, Spinal; Homeostasis; Kinetics; Lidocaine; Neurons; Rats; Saxitoxin; Sodium Channels; Tetrodotoxin

1992
Mu-conotoxins share a common binding site with tetrodotoxin/saxitoxin on eel electroplax Na channels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:5

    Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Conotoxins; Electric Organ; Electrophorus; Ion Channels; Kinetics; Lidocaine; Mollusk Venoms; Saxitoxin; Sodium; Tetrodotoxin; Veratridine

1987
The binding of labelled saxitoxin to the sodium channels in nerve membranes.
    The Journal of physiology, 1973, Volume: 235, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium; Cell Membrane; Fishes; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lidocaine; Neurons; Olfactory Nerve; Rabbits; Saxitoxin; Sodium; Tetrodotoxin; Thallium; Tritium; Vagus Nerve; Veratrine

1973
Differential sensitivities of mammalian nerve fibers to local anesthetic agents.
    Anesthesiology, 1980, Volume: 53, Issue:6

    Topics: Anesthetics; Animals; Bupivacaine; Cocaine; Etidocaine; Lidocaine; Nerve Fibers; Nerve Fibers, Myelinated; Procaine; Rabbits; Saxitoxin; Tetracaine; Tetrodotoxin

1980
Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study.
    The Journal of general physiology, 1994, Volume: 103, Issue:1

    Topics: Animals; Benzocaine; Dogs; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Kinetics; Lidocaine; Myocardium; Purkinje Fibers; Saxitoxin; Sodium Channels

1994
Relationship between action potential, contraction-relaxation pattern, and intracellular Ca2+ transient in cardiomyocytes of dogs with chronic heart failure.
    Cellular and molecular life sciences : CMLS, 1998, Volume: 54, Issue:6

    Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Disease Models, Animal; Dogs; Electrophysiology; Heart; Heart Failure; Lidocaine; Muscle Contraction; Saxitoxin

1998
Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current.
    Cellular and molecular life sciences : CMLS, 1999, Volume: 55, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Calcium; Dogs; Heart; Heart Failure; Ion Transport; Lidocaine; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Potassium; Saxitoxin; Sodium; Sodium Channel Blockers; Sodium Channels

1999
Lidocaine alters activation gating of cardiac Na channels.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 439, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Cell Line; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Humans; Ion Channel Gating; Lidocaine; Myocardium; Saxitoxin; Sodium Channel Blockers; Sodium Channels

2000
Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Amino Acid Substitution; Anesthetics, Local; Animals; Calcium Channel Blockers; Cells, Cultured; Conotoxins; Ethyl Methanesulfonate; Ion Channel Gating; Lidocaine; Mesylates; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Rats; Saxitoxin; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Tetrodotoxin; Transfection; Xenopus laevis

2001
Differential effects of bupivacaine enantiomers, ropivacaine and lidocaine on up-regulation of cell surface voltage-dependent sodium channels in adrenal chromaffin cells.
    Brain research, 2003, Mar-21, Volume: 966, Issue:2

    Topics: Amides; Anesthetics, Local; Animals; Blotting, Northern; Bupivacaine; Cattle; Cells, Cultured; Chromaffin Cells; Enzyme Inhibitors; Lidocaine; Ouabain; Potassium Channel Blockers; Ropivacaine; Saxitoxin; Scorpion Venoms; Sodium; Sodium Channels; Transcription, Genetic; Tritium; Up-Regulation; Veratridine

2003
Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue.
    Pflugers Archiv : European journal of physiology, 2005, Volume: 451, Issue:3

    Topics: Animals; Cadmium; Cell Line; Extracellular Fluid; Ganglia, Spinal; Humans; Intracellular Fluid; Lidocaine; Male; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Saxitoxin; Serine; Sodium; Sodium Channels; Tetrodotoxin

2005
Differential interactions of Na+ channel toxins with T-type Ca2+ channels.
    The Journal of general physiology, 2008, Volume: 132, Issue:1

    Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line; Cells, Cultured; Dogs; Drug Interactions; Humans; Lidocaine; Marine Toxins; Membrane Potentials; Mibefradil; Molecular Sequence Data; Myocytes, Cardiac; Nickel; Saxitoxin; Sequence Homology, Amino Acid; Sodium Channel Blockers; Tetrodotoxin; Transfection

2008
The extract of the jellyfish Phyllorhiza punctata promotes neurotoxic effects.
    Journal of applied toxicology : JAT, 2011, Volume: 31, Issue:8

    Topics: Animals; Chickens; Cnidarian Venoms; Lidocaine; Male; Marine Toxins; Mice; Neuromuscular Junction; Oxocins; Phentolamine; Phospholipases A2; Saxitoxin; Scyphozoa; Specimen Handling; Synaptic Transmission; Tetrodotoxin; Vas Deferens

2011