lidocaine and rifampin

lidocaine has been researched along with rifampin in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (16.67)	18.7374
1990's	5 (20.83)	18.2507
2000's	4 (16.67)	29.6817
2010's	10 (41.67)	24.3611
2020's	1 (4.17)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Artursson, P; Mateus, A; Matsson, P	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Artru, AA; Bowdle, TA; Marathe, PH; Shen, DD	1
Celestin, C; Foster, JR; Patterson, JH; Powell, JR; Rice, TL	1
Belpaire, FM; Bogaert, MG; De Rick, AF; Dello, C	1
Hackshaw, R; Turner, KJ; Wetherall, JD	1
Clee, M; Feely, J; Guy, E; Pereira, L	1
Kaminski, DL; Li, AP; Rasmussen, A; Xu, L	1
Hoener, BA	1
Jurima-Romet, M; Li, AP	1
Nacke, A; Reichel, C; Sauerbruch, T; Skodra, T; Spengler, U	1
Alcouffe, P; Ladavière, C; Montembault, A; Peers, S	1

Reviews

1 review(s) available for lidocaine and rifampin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for lidocaine and rifampin

Article	Year
The lignocaine metabolite (MEGX) liver function test and P-450 induction in humans. British journal of clinical pharmacology, 1998, Volume: 46, Issue:6 Topics: Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Lidocaine; Liver Function Tests; Male; Mixed Function Oxygenases; Reproducibility of Results; Rifampin	1998

Other Studies

22 other study(ies) available for lidocaine and rifampin

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Effect of serum protein binding on the entry of lidocaine into brain and cerebrospinal fluid in dogs. Anesthesiology, 1991, Volume: 75, Issue:5 Topics: Animals; Brain; Dogs; Drug Interactions; Infusions, Intravenous; Lidocaine; Orosomucoid; Protein Binding; Rifampin	1991
Influence of rifampin on tocainide pharmacokinetics in humans. Clinical pharmacy, 1989, Volume: 8, Issue:3 Topics: Adult; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Female; Humans; Lidocaine; Male; Rifampin; Tocainide	1989
Influence of enhanced alpha-1-acid glycoprotein concentration on protein binding, pharmacokinetics and antiarrhythmic effect of lidocaine in the dog. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Dogs; Epinephrine; Heart Rate; Kinetics; Lidocaine; Orosomucoid; Protein Binding; Rifampin	1987
The rat mast cell degranulation assay as an in vitro allergy test. Australian and New Zealand journal of medicine, 1974, Volume: 4, Issue:2 Topics: Age Factors; Animals; Cycloserine; Cytoplasmic Granules; Dextrans; Drug Hypersensitivity; Histamine Release; Humans; Hydrogen-Ion Concentration; Immunoglobulin E; In Vitro Techniques; Insulin; Lidocaine; Mast Cells; Penicillins; Rats; Rifampin	1974
Enzyme induction with rifampicin; lipoproteins and drug binding to alpha 1-acid glycoprotein. British journal of clinical pharmacology, 1983, Volume: 16, Issue:2 Topics: Adult; Aged; Cholesterol; Enzyme Induction; Female; Humans; Lidocaine; Lipoproteins; Male; Middle Aged; Orosomucoid; Protein Binding; Rifampin	1983
Rifampicin induction of lidocaine metabolism in cultured human hepatocytes. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2 Topics: Aged; Cells, Cultured; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Lidocaine; Liver; Male; Middle Aged; Rifampin	1995
Predicting the hepatic clearance of xenobiotics in humans from in vitro data. Biopharmaceutics & drug disposition, 1994, Volume: 15, Issue:4 Topics: Biological Availability; Chlorzoxazone; Cytochrome P-450 Enzyme System; Humans; Hydrocortisone; Lidocaine; Liver; Mathematics; Metabolic Clearance Rate; Mexiletine; Nifedipine; Predictive Value of Tests; Rifampin; Xenobiotics	1994
Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin. Cell biology and toxicology, 1997, Volume: 13, Issue:4-5 Topics: Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Humans; Lidocaine; Liver; Mixed Function Oxygenases; Rifampin; Steroid Hydroxylases; Terfenadine	1997
Embedment of liposomes into chitosan physical hydrogel for the delayed release of antibiotics or anaesthetics, and its first ESEM characterization. Carbohydrate polymers, 2020, Feb-01, Volume: 229 Topics: Anesthetics; Anti-Bacterial Agents; Chitosan; Drug Liberation; Fluoresceins; Hydrogels; Lidocaine; Liposomes; Microscopy, Electron, Scanning; Rheology; Rifampin	2020