lidocaine has been researched along with ranitidine in 38 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (23.68) | 18.7374 |
1990's | 1 (2.63) | 18.2507 |
2000's | 15 (39.47) | 29.6817 |
2010's | 13 (34.21) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Gozalbes, R; Pineda-Lucena, A | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Artursson, P; Mateus, A; Matsson, P | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Collier, PS; Flynn, RJ; Howard, PJ; Moore, J | 1 |
Heath, CA; Johnson, RF; Roberts, RK; Schenker, S; Speeg, KV | 1 |
Kapil, RP; Lalonde, RL; Mattern, AL; North, DS | 1 |
Cheek, DB; Dailey, PA; Healy, K; Hughes, SC; Rosen, MA; Shnider, SM | 1 |
Kim, KC; Tasch, MD | 1 |
Bentley, JB; Fukui, T; Gandolfi, AJ; Glass, SJ; Jackson, JE; Plachetka, JR | 1 |
Birkett, DJ; Lillywhite, KJ; Miners, JO; Robson, RA; Wing, LM | 1 |
Wood, JR | 1 |
Feely, J; Guy, E | 1 |
King, AD; Stewart, JT; Warren, FW | 1 |
Al Obaid, AR; Al Rasheed, NM; Al Sayed, MI; Al Zuhair, HH; Fatani, AJ | 1 |
Mata, JL; Restolho, J; Saramago, B | 1 |
1 review(s) available for lidocaine and ranitidine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
4 trial(s) available for lidocaine and ranitidine
Article | Year |
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Single dose oral H2-antagonists do not affect plasma lidocaine levels in the parturient.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Cimetidine; Drug Interactions; Female; Fetal Blood; Humans; Lidocaine; Pregnancy; Randomized Controlled Trials as Topic; Ranitidine | 1989 |
The effect of histamine-2 receptor antagonists on tocainide pharmacokinetics.
Topics: Adult; Anti-Arrhythmia Agents; Cimetidine; Drug Interactions; Female; Half-Life; Histamine H2 Antagonists; Humans; Lidocaine; Male; Middle Aged; Ranitidine; Tocainide | 1988 |
Effects of histamine-2 receptor blockade on lidocaine kinetics.
Topics: Administration, Oral; Adult; Analysis of Variance; Chromatography, High Pressure Liquid; Cimetidine; Double-Blind Method; Drug Interactions; Half-Life; Humans; Infusions, Parenteral; Kinetics; Lidocaine; Male; Orosomucoid; Ranitidine | 1985 |
Lack of effect of ranitidine on the disposition of lignocaine.
Topics: Adult; Female; Furans; Half-Life; Histamine H2 Antagonists; Humans; Kinetics; Lidocaine; Male; Ranitidine | 1983 |
33 other study(ies) available for lidocaine and ranitidine
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Effect of H2-receptor antagonists on steady-state extraction of indocyanine green and lidocaine by the perfused rat liver.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Indocyanine Green; Lidocaine; Liver; Male; Oxygen Consumption; Perfusion; Ranitidine; Rats; Rats, Inbred Strains | 1986 |
Effect of cimetidine and ranitidine on lidocaine concentrations during epidural anesthesia for cesarean section.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Cimetidine; Female; Fetal Blood; Humans; Lidocaine; Pregnancy; Ranitidine | 1988 |
Effects of cimetidine and ranitidine on local anesthetic central nervous system toxicity in mice.
Topics: Anesthetics, Local; Animals; Brain Diseases; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Lidocaine; Mice; Procaine; Ranitidine; Seizures | 1986 |
The effect of ranitidine on the disposition of lignocaine.
Topics: Adolescent; Adult; Biological Availability; Drug Interactions; Female; Humans; Lidocaine; Male; Metabolic Clearance Rate; Ranitidine | 1985 |
H2 receptor antagonists: cimetidine and ranitidine.
Topics: Cimetidine; Drug Interactions; Furans; Guanidines; Histamine H2 Antagonists; Humans; Lidocaine; Propranolol; Ranitidine | 1983 |
Stability of ranitidine hydrochloride and seven medications.
Topics: Aminophylline; Chromatography, High Pressure Liquid; Dobutamine; Dopamine; Drug Stability; Humans; Lidocaine; Methylprednisolone; Nitroprusside; Norepinephrine; Ranitidine; Sodium Chloride | 1994 |
Effects of two newly synthesized analogues of lidocaine on rat arterial blood pressure and heart rate.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Benzoates; Blood Pressure; Calcium Chloride; Cyproheptadine; Enzyme Inhibitors; Heart Rate; Hexamethonium; Histamine Agonists; Indomethacin; Lidocaine; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Pyrilamine; Quinacrine; Ranitidine; Rats; Rats, Wistar; Vasodilator Agents | 2001 |
Peculiar surface behavior of some ionic liquids based on active pharmaceutical ingredients.
Topics: Dioctyl Sulfosuccinic Acid; Ibuprofen; Ionic Liquids; Lidocaine; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Ranitidine; Surface Tension; Temperature | 2011 |