lidocaine and pindolol

lidocaine has been researched along with pindolol in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (42.22)	18.7374
1990's	3 (6.67)	18.2507
2000's	15 (33.33)	29.6817
2010's	8 (17.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Caron, G; Ermondi, G	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahman, M; Holmén, AG; Wan, H	1
Bard, B; Carrupt, PA; Martel, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Atsmon, A; Epstein, O; Schoenfeld, N	3
Doshchitsin, VL	1
Doshchitsin, VL; Fedorova, IF; Gendlin, GE; Pozin, VM; Skuratovskaia, SG	1
Holmboe, J; Lilleåsen, P; Normann, E	1
Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB	1
Mannhold, R; Voigt, W	1
Gorzalka, BB; Mendelson, SD	1
Szekeres, L	2
Huupponen, R; Salminen, L	1
Bender, F; Bräuer, B; Brisse, B; Müller, W	1
Iven, H; Pursche, R; Zetler, G	1
Arita, M; Kiyosue, T	1
Gordin, A; Heikkilä, J; Leinonen, H; Sundberg, S	1
Sekeresh, L	1
Koltai, M; Leprán, I; Siegmund, W; Szekeres, L	1
Steiness, E; Svendsen, TL; Tangø, M; Trap-Jensen, J; Waldorff, S	1
Izumi, F; Kobayashi, H; Kuroiwa, A; Mizuki, T; Nakashima, Y	1
Kim, Y	1
Fraudeau, C; Luck, G; Mangani, F; Vérette, E	1
Andrade, R; Béïque, JC; Chapin-Penick, EM; Mladenovic, L	1
Ishii, K; Karikomi, Y; Kubota, Y; Nakahara, T; Sakamoto, K	1

Reviews

1 review(s) available for lidocaine and pindolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for lidocaine and pindolol

Article	Year
Lorcainide in the prophylaxis of ventricular arrhythmias in acute myocardial infarction. Annals of clinical research, 1984, Volume: 16, Issue:1 Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Female; Humans; Infusions, Parenteral; Lidocaine; Male; Middle Aged; Myocardial Infarction; Pindolol; Piperidines; Random Allocation	1984
Effects of propranolol and pindolol on plasma lignocaine clearance in man. British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2 Topics: Adult; Cardiac Output; Drug Interactions; Heart Rate; Hemodynamics; Humans; Kinetics; Lidocaine; Male; Pindolol; Propranolol	1982

Other Studies

42 other study(ies) available for lidocaine and pindolol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists. Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3 Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Inhibitory effect of membrane active compounds on induction of tyrosine aminotransferase in chick embryo liver cells in culture. FEBS letters, 1977, Feb-01, Volume: 73, Issue:2 Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cells, Cultured; Chick Embryo; Dexamethasone; Enzyme Induction; Kinetics; Lidocaine; Liver; Pindolol; Practolol; Propranolol; Quinidine; Tyrosine Transaminase	1977
Inhibitory effect of some membrane active drugs on RNA and DNA synthesis in cultured chick embryo liver cells. Biochemical and biophysical research communications, 1976, May-23, Volume: 76, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Cells, Cultured; Chick Embryo; DNA; Kinetics; Lidocaine; Liver; Oxprenolol; Pindolol; Propranolol; Quinidine; RNA; Thymidine; Uridine	1976
Inhibitory effect of membrane active compounds on the uptake of 14C-alpha-aminoisobutyric acid (AIB) in cultured chick embryo liver cells. Life sciences, 1977, Aug-01, Volume: 21, Issue:3 Topics: Adrenergic beta-Antagonists; Aminoisobutyric Acids; Animals; Chick Embryo; Lidocaine; Liver; Oxprenolol; Pindolol; Practolol; Propranolol; Quinidine	1977
[Comparative evaluation of new drugs used in the treatment of cardiac arrhythmia]. Kardiologiia, 1975, Volume: 15, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Ajmaline; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barbiturates; Drug Combinations; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Pindolol; Practolol; Propranolol; Sparteine; Verapamil	1975
[Prevention of ventricular fibrillation in animal experiments]. Kardiologiia, 1978, Volume: 18, Issue:4 Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Drug Evaluation; Lidocaine; Pindolol; Rats; Ventricular Fibrillation; Verapamil	1978
Pindolol (Viscén) in persistent ventricular fibrillation. A case report. Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:1 Topics: Aged; Aortic Aneurysm; Electric Countershock; Female; Humans; Lidocaine; Pindolol; Resuscitation; Tachycardia; Ventricular Fibrillation	1976
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:5 Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metoprolol; Myocardial Contraction; Pindolol; Propranolol; Time Factors; Ventricular Fibrillation	1987
Characterization, localization and pharmacological profile of a high-affinity [3H]lidocaine binding site. European journal of pharmacology, 1989, Oct-04, Volume: 169, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Binding Sites; Binding, Competitive; Cattle; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Iodocyanopindolol; Kinetics; Lidocaine; Liver; Mitochondria, Liver; Myocardium; Pindolol; Sarcolemma; Subcellular Fractions; Tissue Distribution	1989
Stimulation of beta-adrenoceptors inhibits lordosis behavior in the female rat. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4 Topics: Animals; Estradiol; Female; Isomerism; Lidocaine; Metoprolol; Pindolol; Posture; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sexual Behavior, Animal	1988
Cardioprotection by anti-ischaemic and cytoprotective drugs. Basic research in cardiology, 1987, Volume: 82 Suppl 2 Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Death, Sudden; Dietary Fats; Epoprostenol; Humans; Lidocaine; Linoleic Acid; Linoleic Acids; Myocardial Infarction; Pindolol	1987
Transient corneal anaesthesia after topical pindolol in rabbits. Acta ophthalmologica, 1985, Volume: 63, Issue:1 Topics: Anesthetics, Local; Animals; Cornea; Lidocaine; Ophthalmic Solutions; Pindolol; Placebos; Rabbits	1985
[Plasma and tissue catecholamine concentration and antiarrhythmic influence on it]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79 Topics: Animals; Anti-Arrhythmia Agents; Catecholamines; Humans; Lidocaine; Male; Pindolol; Practolol; Rats; Verapamil	1973
Field-stimulus response of guinea-pig atria as influenced by the peptides angiotensin, bradykinin, and substance P. Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 312, Issue:1 Topics: Angiotensin II; Animals; Bradykinin; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Pindolol; Substance P; Tetrodotoxin; Vas Deferens	1980
Modification of "depressed fast channel dependent slow conduction" by lidocaine and verapamil in the presence or absence of catecholamines--evidence for alteration of preferential ionic channels for slow conduction. Japanese circulation journal, 1983, Volume: 47, Issue:1 Topics: Action Potentials; Animals; Catecholamines; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Ion Channels; Isoproterenol; Lidocaine; Microelectrodes; Myocardial Infarction; Papillary Muscles; Pindolol; Potassium; Verapamil	1983
A pharmacological evaluation of electrical events in the myocardium. Advances in myocardiology, 1982, Volume: 3 Topics: Animals; Calcium; Cardiac Output; Coronary Circulation; Dogs; Electrocardiography; Heart; Heart Rate; Ion Channels; Lidocaine; Myocardial Contraction; Myocardium; Pindolol; Potassium; Purkinje Fibers; Rabbits; Sinoatrial Node; Sodium-Potassium-Exchanging ATPase; Verapamil	1982
[Pharmacologic evaluation of electrical processes in the myocardium]. Kardiologiia, 1982, Volume: 22, Issue:8 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electrophysiology; Heart; Heart Conduction System; In Vitro Techniques; Lidocaine; Nitroglycerin; Pindolol; Verapamil	1982
Coronary artery ligation, early arrhythmias, and determination of the ischemic area in conscious rats. Journal of pharmacological methods, 1983, Volume: 9, Issue:3 Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Coronary Vessels; Disease Models, Animal; Lidocaine; Ligation; Male; Myocardial Infarction; Pindolol; Rats; Rats, Inbred Strains	1983
Lidocaine increases the number of beta-adrenoceptors in neonatal rat cardiocytes in culture. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:2 Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Cell Membrane; Cells, Cultured; Female; Heart; Iodocyanopindolol; Lidocaine; Male; Myocardium; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Up-Regulation	1994
Interaction between beta blockers and epinephrine on hemodynamics of spontaneously hypertensive rats. Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:1 Topics: Acebutolol; Adult; Animals; Body Weight; Drug Interactions; Epinephrine; Female; Hemodynamics; Humans; Lidocaine; Lung; Male; Pindolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity	1993
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation. Journal of chromatography. A, 1997, Feb-21, Volume: 762, Issue:1-2 Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil	1997
Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex. The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Bicuculline; Fluorobenzenes; GABA-A Receptor Antagonists; Glutamic Acid; Indoles; Lidocaine; Male; Patch-Clamp Techniques; Phenols; Pindolol; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors	2004
Characterization of mexiletine as an antagonist of beta-adrenoceptor in Chinese hamster ovary cells expressing cloned human beta-adrenoceptors. Biochemical pharmacology, 2004, Mar-01, Volume: 67, Issue:5 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Lidocaine; Mexiletine; Pindolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Transfection	2004