lidocaine and pindolol

lidocaine has been researched along with pindolol in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199019 (42.22)18.7374
1990's3 (6.67)18.2507
2000's15 (33.33)29.6817
2010's8 (17.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Caron, G; Ermondi, G1
Abraham, MH; Acree, WE; Ibrahim, A1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahman, M; Holmén, AG; Wan, H1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Atsmon, A; Epstein, O; Schoenfeld, N3
Doshchitsin, VL1
Doshchitsin, VL; Fedorova, IF; Gendlin, GE; Pozin, VM; Skuratovskaia, SG1
Holmboe, J; Lilleåsen, P; Normann, E1
Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB1
Mannhold, R; Voigt, W1
Gorzalka, BB; Mendelson, SD1
Szekeres, L2
Huupponen, R; Salminen, L1
Bender, F; Bräuer, B; Brisse, B; Müller, W1
Iven, H; Pursche, R; Zetler, G1
Arita, M; Kiyosue, T1
Gordin, A; Heikkilä, J; Leinonen, H; Sundberg, S1
Sekeresh, L1
Koltai, M; Leprán, I; Siegmund, W; Szekeres, L1
Steiness, E; Svendsen, TL; Tangø, M; Trap-Jensen, J; Waldorff, S1
Izumi, F; Kobayashi, H; Kuroiwa, A; Mizuki, T; Nakashima, Y1
Kim, Y1
Fraudeau, C; Luck, G; Mangani, F; Vérette, E1
Andrade, R; Béïque, JC; Chapin-Penick, EM; Mladenovic, L1
Ishii, K; Karikomi, Y; Kubota, Y; Nakahara, T; Sakamoto, K1

Reviews

1 review(s) available for lidocaine and pindolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for lidocaine and pindolol

ArticleYear
Lorcainide in the prophylaxis of ventricular arrhythmias in acute myocardial infarction.
    Annals of clinical research, 1984, Volume: 16, Issue:1

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Female; Humans; Infusions, Parenteral; Lidocaine; Male; Middle Aged; Myocardial Infarction; Pindolol; Piperidines; Random Allocation

1984
Effects of propranolol and pindolol on plasma lignocaine clearance in man.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Adult; Cardiac Output; Drug Interactions; Heart Rate; Hemodynamics; Humans; Kinetics; Lidocaine; Male; Pindolol; Propranolol

1982

Other Studies

42 other study(ies) available for lidocaine and pindolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Inhibitory effect of membrane active compounds on induction of tyrosine aminotransferase in chick embryo liver cells in culture.
    FEBS letters, 1977, Feb-01, Volume: 73, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cells, Cultured; Chick Embryo; Dexamethasone; Enzyme Induction; Kinetics; Lidocaine; Liver; Pindolol; Practolol; Propranolol; Quinidine; Tyrosine Transaminase

1977
Inhibitory effect of some membrane active drugs on RNA and DNA synthesis in cultured chick embryo liver cells.
    Biochemical and biophysical research communications, 1976, May-23, Volume: 76, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cells, Cultured; Chick Embryo; DNA; Kinetics; Lidocaine; Liver; Oxprenolol; Pindolol; Propranolol; Quinidine; RNA; Thymidine; Uridine

1976
Inhibitory effect of membrane active compounds on the uptake of 14C-alpha-aminoisobutyric acid (AIB) in cultured chick embryo liver cells.
    Life sciences, 1977, Aug-01, Volume: 21, Issue:3

    Topics: Adrenergic beta-Antagonists; Aminoisobutyric Acids; Animals; Chick Embryo; Lidocaine; Liver; Oxprenolol; Pindolol; Practolol; Propranolol; Quinidine

1977
[Comparative evaluation of new drugs used in the treatment of cardiac arrhythmia].
    Kardiologiia, 1975, Volume: 15, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Ajmaline; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barbiturates; Drug Combinations; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Pindolol; Practolol; Propranolol; Sparteine; Verapamil

1975
[Prevention of ventricular fibrillation in animal experiments].
    Kardiologiia, 1978, Volume: 18, Issue:4

    Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Drug Evaluation; Lidocaine; Pindolol; Rats; Ventricular Fibrillation; Verapamil

1978
Pindolol (Viscén) in persistent ventricular fibrillation. A case report.
    Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:1

    Topics: Aged; Aortic Aneurysm; Electric Countershock; Female; Humans; Lidocaine; Pindolol; Resuscitation; Tachycardia; Ventricular Fibrillation

1976
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol.
    Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:5

    Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metoprolol; Myocardial Contraction; Pindolol; Propranolol; Time Factors; Ventricular Fibrillation

1987
Characterization, localization and pharmacological profile of a high-affinity [3H]lidocaine binding site.
    European journal of pharmacology, 1989, Oct-04, Volume: 169, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Binding Sites; Binding, Competitive; Cattle; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Iodocyanopindolol; Kinetics; Lidocaine; Liver; Mitochondria, Liver; Myocardium; Pindolol; Sarcolemma; Subcellular Fractions; Tissue Distribution

1989
Stimulation of beta-adrenoceptors inhibits lordosis behavior in the female rat.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4

    Topics: Animals; Estradiol; Female; Isomerism; Lidocaine; Metoprolol; Pindolol; Posture; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sexual Behavior, Animal

1988
Cardioprotection by anti-ischaemic and cytoprotective drugs.
    Basic research in cardiology, 1987, Volume: 82 Suppl 2

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Death, Sudden; Dietary Fats; Epoprostenol; Humans; Lidocaine; Linoleic Acid; Linoleic Acids; Myocardial Infarction; Pindolol

1987
Transient corneal anaesthesia after topical pindolol in rabbits.
    Acta ophthalmologica, 1985, Volume: 63, Issue:1

    Topics: Anesthetics, Local; Animals; Cornea; Lidocaine; Ophthalmic Solutions; Pindolol; Placebos; Rabbits

1985
[Plasma and tissue catecholamine concentration and antiarrhythmic influence on it].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Animals; Anti-Arrhythmia Agents; Catecholamines; Humans; Lidocaine; Male; Pindolol; Practolol; Rats; Verapamil

1973
Field-stimulus response of guinea-pig atria as influenced by the peptides angiotensin, bradykinin, and substance P.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 312, Issue:1

    Topics: Angiotensin II; Animals; Bradykinin; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Pindolol; Substance P; Tetrodotoxin; Vas Deferens

1980
Modification of "depressed fast channel dependent slow conduction" by lidocaine and verapamil in the presence or absence of catecholamines--evidence for alteration of preferential ionic channels for slow conduction.
    Japanese circulation journal, 1983, Volume: 47, Issue:1

    Topics: Action Potentials; Animals; Catecholamines; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Ion Channels; Isoproterenol; Lidocaine; Microelectrodes; Myocardial Infarction; Papillary Muscles; Pindolol; Potassium; Verapamil

1983
A pharmacological evaluation of electrical events in the myocardium.
    Advances in myocardiology, 1982, Volume: 3

    Topics: Animals; Calcium; Cardiac Output; Coronary Circulation; Dogs; Electrocardiography; Heart; Heart Rate; Ion Channels; Lidocaine; Myocardial Contraction; Myocardium; Pindolol; Potassium; Purkinje Fibers; Rabbits; Sinoatrial Node; Sodium-Potassium-Exchanging ATPase; Verapamil

1982
[Pharmacologic evaluation of electrical processes in the myocardium].
    Kardiologiia, 1982, Volume: 22, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electrophysiology; Heart; Heart Conduction System; In Vitro Techniques; Lidocaine; Nitroglycerin; Pindolol; Verapamil

1982
Coronary artery ligation, early arrhythmias, and determination of the ischemic area in conscious rats.
    Journal of pharmacological methods, 1983, Volume: 9, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Coronary Vessels; Disease Models, Animal; Lidocaine; Ligation; Male; Myocardial Infarction; Pindolol; Rats; Rats, Inbred Strains

1983
Lidocaine increases the number of beta-adrenoceptors in neonatal rat cardiocytes in culture.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:2

    Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Cell Membrane; Cells, Cultured; Female; Heart; Iodocyanopindolol; Lidocaine; Male; Myocardium; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Up-Regulation

1994
Interaction between beta blockers and epinephrine on hemodynamics of spontaneously hypertensive rats.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:1

    Topics: Acebutolol; Adult; Animals; Body Weight; Drug Interactions; Epinephrine; Female; Hemodynamics; Humans; Lidocaine; Lung; Male; Pindolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity

1993
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
    Journal of chromatography. A, 1997, Feb-21, Volume: 762, Issue:1-2

    Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil

1997
Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Bicuculline; Fluorobenzenes; GABA-A Receptor Antagonists; Glutamic Acid; Indoles; Lidocaine; Male; Patch-Clamp Techniques; Phenols; Pindolol; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors

2004
Characterization of mexiletine as an antagonist of beta-adrenoceptor in Chinese hamster ovary cells expressing cloned human beta-adrenoceptors.
    Biochemical pharmacology, 2004, Mar-01, Volume: 67, Issue:5

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Lidocaine; Mexiletine; Pindolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Transfection

2004