lidocaine and phenobarbital

lidocaine has been researched along with phenobarbital in 84 studies

Research

Studies (84)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (51.19)	18.7374
1990's	5 (5.95)	18.2507
2000's	22 (26.19)	29.6817
2010's	11 (13.10)	24.3611
2020's	3 (3.57)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Caron, G; Ermondi, G	1
Carrupt, PA; Martel, S; Ottaviani, G	2
Abraham, MH; Acree, WE; Ibrahim, A	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A	1
Blaschke, TF; Esquivel, M; Meffin, PJ; Snidow, GH	1
Browne, TR	2
Takman, BH	1
Jalling, B	1
Chandra, HK; Jain, PD; Pandey, K	1
Chundela, B; Slechtová, R	1
Garrettson, LK; McGee, EB	1
Gavilanes, FG; Guillen, A; Haro, A; Municio, AM	1
Carvalho, RR; Cunha, FQ; Fingola, FF; Freitas, JC; Menezes, MA; Paumgartten, FJ; Presgrave, OA	1
Gomez, J; Rodriguez, A	1
Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ	1
Liu, RL; Wang, J; Yan, SQ; Zhu, XY	1
Nakahira, Y	1
Paterson, P; Skett, P	1
Huet, PM; Varin, F	1
Delgado, JM; Kitahata, LM	1
Hambert, O; Petersén, I	1
Fink, BR; Kenny, GE; Simpson, WE	1
Aston, R; Roberts, VL	1
Epstein, RA; Jackson, SH	1
Bigger, JT; Strauss, HC	1
Branch, RA; Nies, AS; Shand, DG	1
Kazama, K	1
Grundin, R; Moldéus, P; Orrenius, S; von Bahr, C	1
Brown, RE; DiFazio, C	1
Gamstorp, I	1
Heinonen, J; Jarho, L; Takki, S	1
Cosmides, GJ	1
Southgate, PJ	1
Kendig, JJ	1
Oppenheimer, EY; Rosman, NP	1
Bleck, TP	1
Barber, K; Chen, SM; Ferguson, R; Kramer, MS; Raja, RM	1
Erenberg, G; Rothner, AD	1
Bruni, J	1
Kusek, JC	1
Zenk, KE	1
Escobar, A; Montenegro, R	1
Murphy, JL	1
Rosenberg, CA	1
Fujimori, M; Funae, Y; Imaoka, S; Nakamoto, T; Oda, Y	1
Berger, I; Schimmel, MS; Schlesinger, Y; Seelenfreund, M; Steinberg, A	1
Boylan, GB; Rennie, JM	1
BERNHARD, CG; BOHM, E; KIRSTEIN, L; WIESEL, T	1
BEGUIN, M; FLEURY, C; FROMMEL, E; VON LEDEBUR, I	1
FREY, HH	1
HEINONEN, J	1
OTTOSSON, JO	1
Berman, DA; Graber, M; Porter, RS	1
Binnie, CD; Boylan, GB; Chorley, G; Farrer, K; Fox, GF; Morton, M; Pressler, RM; Rennie, JM	1
Negoro, T; Okumura, A; Uemura, N; Watanabe, K	1
Chan, TC; Davis, DP; Jin, A; Vilke, GM	1
Guy, RH; Kalia, YN; Sekkat, N	1
Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT	1
Bos, AF; Brouwer, OF; Roze, E; Ter Horst, HJ; van der Heide, MJ; van der Veere, CN	1
de Vries, LS; Hellström-Westas, L; van Rooij, LG	1
Ågren, J; Flink, R; Hellström-Westas, L; Lundqvist, M; Wickström, R	1
Hong, SM; Lee, HS; Moon, SB	1
Amsterdam, EA; Singh, GD; Southard, JA; Wong, GB	1
El-Dib, M; Soul, JS	1
García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V	1
Criscione, R; Falsaperla, R; Marino, S; Pisani, F; Praticò, A; Ruggieri, M; Sortino, V	1

Reviews

12 review(s) available for lidocaine and phenobarbital

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug therapy reviews: drug therapy of status epilepticus. American journal of hospital pharmacy, 1978, Volume: 35, Issue:8 Topics: Anesthesia, General; Diazepam; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Kinetics; Lidocaine; Neuromuscular Nondepolarizing Agents; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus	1978
Digitalis toxicity: drug interactions promoting toxicity and the management of toxicity. Seminars in drug treatment, 1972,Autumn, Volume: 2, Issue:2 Topics: Adrenergic beta-Antagonists; Anesthetics; Anticholesteremic Agents; Arrhythmias, Cardiac; Cathartics; Digitalis Glycosides; Digitoxin; Digoxin; Diuretics; Drug Interactions; Heart Conduction System; Heart Rate; Humans; Intestinal Absorption; Ion Exchange Resins; Lidocaine; Liver Circulation; Phenobarbital; Phenytoin; Potassium; Protein Binding	1972
Hemodynamic drug interactions. Cardiovascular clinics, 1974, Volume: 6, Issue:2 Topics: Animals; Antipyrine; Dogs; Dopamine; Drug Interactions; Enzyme Induction; Glucagon; Half-Life; Hemodynamics; Humans; Lidocaine; Liver Circulation; Macaca mulatta; Metabolic Clearance Rate; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Propranolol; Time Factors	1974
Seizures and seizure-like states in the child: an approach to emergency management. Emergency medicine clinics of North America, 1983, Volume: 1, Issue:1 Topics: Anesthesia, General; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Emergencies; Humans; Infant; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Seizures; Sleep Wake Disorders; Status Epilepticus; Syncope	1983
Therapy for status epilepticus. Clinical neuropharmacology, 1983, Volume: 6, Issue:4 Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid	1983
An overview of perinatal clinical pharmacology. Clinics in laboratory medicine, 1981, Volume: 1, Issue:2 Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline	1981
Neonatal seizures and their treatment. Current opinion in neurology, 2003, Volume: 16, Issue:2 Topics: Anticonvulsants; Brain; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Neuronal Plasticity; Phenobarbital; Phenytoin; Prognosis; Seizures	2003
Treatment of neonatal seizures. Seminars in fetal & neonatal medicine, 2013, Volume: 18, Issue:4 Topics: Animals; Anticonvulsants; Brain; Child Development; Drug Resistance; Epilepsy; Humans; Infant, Newborn; Infant, Premature; Lidocaine; Midazolam; Neurogenesis; Neurons; Neuroprotective Agents; Phenobarbital; Premature Birth; Seizures; Severity of Illness Index	2013
The use of phenobarbital and other anti-seizure drugs in newborns. Seminars in fetal & neonatal medicine, 2017, Volume: 22, Issue:5 Topics: Anticonvulsants; Fructose; Humans; Hypothermia, Induced; Infant, Newborn; Lidocaine; Midazolam; Phenobarbital; Seizures; Topiramate; Treatment Outcome	2017
[Paediatric status epilepticus]. Revista de neurologia, 2022, 10-16, Volume: 75, Issue:8 Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid	2022
Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review. Acta bio-medica : Atenei Parmensis, 2022, 12-16, Volume: 93, Issue:6 Topics: Anticonvulsants; Bumetanide; Epilepsy; Humans; Infant, Newborn; Infant, Newborn, Diseases; Levetiracetam; Lidocaine; Midazolam; Phenobarbital; Stroke	2022

Trials

3 trial(s) available for lidocaine and phenobarbital

Article	Year
The GI Cocktail is no more effective than plain liquid antacid: a randomized, double blind clinical trial. The Journal of emergency medicine, 2003, Volume: 25, Issue:3 Topics: Adult; Anesthetics, Local; Antacids; Atropine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Dyspepsia; Emergency Service, Hospital; Female; Humans; Lidocaine; Male; Middle Aged; Phenobarbital; Prospective Studies; Scopolamine; Treatment Outcome	2003
Second-line anticonvulsant treatment of neonatal seizures: a video-EEG monitoring study. Neurology, 2004, Feb-10, Volume: 62, Issue:3 Topics: Anticonvulsants; Clonazepam; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Infant, Newborn; Lidocaine; Male; Midazolam; Phenobarbital; Psychomotor Disorders; Treatment Failure; Video Recording	2004
Prospective randomized study of viscous lidocaine versus benzocaine in a GI cocktail for dyspepsia. The Journal of emergency medicine, 2004, Volume: 27, Issue:1 Topics: Adult; Aluminum Hydroxide; Anesthetics, Local; Antacids; Atropine; Benzocaine; Drug Combinations; Drug Therapy, Combination; Dyspepsia; Female; Humans; Lidocaine; Magnesium Hydroxide; Male; Phenobarbital; Prospective Studies; Scopolamine; Simethicone; Single-Blind Method; Treatment Outcome	2004

Other Studies

69 other study(ies) available for lidocaine and phenobarbital

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13 Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water	2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation. European journal of medicinal chemistry, 2008, Volume: 43, Issue:11 Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity. Bioorganic & medicinal chemistry letters, 2021, 10-01, Volume: 49 Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines	2021
Effect of phenobarbitone on the disposition of lignocaine and warfarin in the dog. The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:12 Topics: Animals; Biological Availability; Dogs; Drug Interactions; Lidocaine; Liver Circulation; Phenobarbital; Time Factors; Warfarin	1978
Drug therapy of status epilepticus. The Journal of the Maine Medical Association, 1978, Volume: 69, Issue:7 Topics: Acetazolamide; Diazepam; Humans; Lidocaine; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus	1978
The chemistry of local anaesthetic agents: classification of blocking agents. British journal of anaesthesia, 1975, Volume: 47 suppl Topics: Anesthetics, Local; Benzocaine; Benzyl Compounds; Binding Sites; Binding, Competitive; Cell Membrane; Lidocaine; Models, Molecular; Neural Conduction; Neurilemma; Phenobarbital; Phenols; Saxitoxin; Sodium; Structure-Activity Relationship; Succinimides; Tetrodotoxin	1975
Plasma concentrations of phenobarbital in the treatment of seizures in newborns. Acta paediatrica Scandinavica, 1975, Volume: 64, Issue:3 Topics: Administration, Oral; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Infant, Premature; Injections, Intramuscular; Lidocaine; Male; Phenobarbital; Seizures; Tablets	1975
Diazepam prophylaxis for lignocaine induced convulsions. Anaesthesia and intensive care, 1975, Volume: 3, Issue:4 Topics: Animals; Diazepam; Gait; Injections, Intraperitoneal; Lidocaine; Phenobarbital; Rats; Seizures; Wakefulness	1975
[Use of gas chromatography--mass spectrometry system in toxicology]. Ceskoslovenska patologie, 1975, Volume: 11, Issue:4 Topics: Chromatography, Gas; Ephedrine; Forensic Medicine; Humans; Lidocaine; Lysergic Acid Diethylamide; Mass Spectrometry; Meperidine; Morphine; Phenobarbital; Tranquilizing Agents	1975
Rapid onset of seizures following aspiration of viscous lidocaine. Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:3 Topics: Drainage, Postural; Extracorporeal Membrane Oxygenation; Female; Humans; Inappropriate ADH Syndrome; Infant; Infant, Newborn; Lidocaine; Phenobarbital; Pneumonia, Aspiration; Seizures; Viscosity	1992
Ceratitis capitata brain adenylate cyclase and its membrane environment. Archives of biochemistry and biophysics, 1991, May-01, Volume: 286, Issue:2 Topics: Adenylyl Cyclases; Animals; Benzyl Alcohol; Benzyl Alcohols; Brain; Cell Membrane; Diptera; Fatty Acids; Kinetics; Lidocaine; Membrane Lipids; Phenobarbital; Phospholipids	1991
Comparison of five methods for the determination of lethal dose in acute toxicity studies. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1989, Volume: 22, Issue:8 Topics: Animal Testing Alternatives; Animals; Female; Hexachlorophene; Lethal Dose 50; Lidocaine; Male; Methanol; Mice; Phenobarbital; Physostigmine	1989
An evaluation of the results of a drug sample analysis. Bulletin on narcotics, 1989, Volume: 41, Issue:1-2 Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Methaqualone; Phenobarbital; Procaine; Spain; Substance-Related Disorders	1989
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system. American journal of nephrology, 1986, Volume: 6, Issue:2 Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin	1986
[First pass effect of gallanilide in rats]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Carbon Tetrachloride Poisoning; Chloramphenicol; Drug Incompatibility; Female; Gallic Acid; Lidocaine; Male; Phenobarbital; Rats; Ventricular Fibrillation	1988
[Metabolism of lidocaine by cytochrome P-450]. Masui. The Japanese journal of anesthesiology, 1988, Volume: 37, Issue:3 Topics: Animals; Cytochrome P-450 Enzyme System; Female; Lidocaine; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors	1988
Sex differences in the effects of microsomal enzyme inducers on hepatic phase I drug metabolism in the rat. Biochemical pharmacology, 1985, Oct-01, Volume: 34, Issue:19 Topics: Animals; Cytochrome P-450 Enzyme System; Dioxoles; Ethanol; Female; Imipramine; Lidocaine; Male; Microsomes, Liver; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Sex Characteristics	1985
Hepatic microcirculation in the perfused cirrhotic rat liver. The Journal of clinical investigation, 1985, Volume: 76, Issue:5 Topics: Animals; Extracellular Space; Lidocaine; Liver; Liver Cirrhosis; Male; Microcirculation; Microspheres; Perfusion; Phenobarbital; Rats; Sucrose	1985
Reversible depression of hippocampus by local injections of anesthetics in monkeys. Electroencephalography and clinical neurophysiology, 1967, Volume: 22, Issue:5 Topics: Amygdala; Anesthetics, Local; Animals; Basal Ganglia; Dibucaine; Electroencephalography; Electrophysiology; Haplorhini; Hippocampus; Hypothalamus; Injections; Lidocaine; Phenobarbital; Thalamus	1967
Clinical, electroencephalographical and neuropharmacological studies in syndromes of progressive myoclonus epilepsy. Acta neurologica Scandinavica, 1970, Volume: 46, Issue:2 Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Amobarbital; Benzazepines; Chloral Hydrate; Chlormethiazole; Chlorpromazine; Chlorprothixene; Diazepam; Electroencephalography; Electromyography; Epilepsy, Tonic-Clonic; Ethanol; Female; Humans; Injections, Intravenous; Lidocaine; Male; Mephenesin; Myoclonus; Phenobarbital; Sleep; Succinylcholine	1970
Anesthetic potency compared with intensity of effect on oxygen consumption in monolayer cultures. Proceedings of the Western Pharmacology Society, 1968, Volume: 11 Topics: Amobarbital; Anesthetics; Anesthetics, Local; Animals; Barbiturates; Chloroform; Culture Techniques; Dibucaine; Ethers; Ethyl Ethers; Halothane; Lidocaine; Methohexital; Methoxyflurane; Mice; Oxygen Consumption; Phenobarbital; Prilocaine; Procaine; Secobarbital; Tetracaine; Thiamylal; Thiopental	1968
Quantitative aspects of vibration-induced mortality. Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2 Topics: Amphetamine; Animals; Atropine; Chlordiazepoxide; Dextroamphetamine; Epinephrine; Hexamethonium Compounds; Isoproterenol; Lidocaine; Male; Mice; Motion Sickness; Neostigmine; Phenobarbital; Phenoxybenzamine; Phenylephrine; Piperazines; Statistics as Topic; Sympathomimetics; Time Factors; Vibration	1969
The metabolic effects of nonvolatile anesthetics on mammalian hepatoma cells in vitro. I. Inhibition of cell replication. Anesthesiology, 1971, Volume: 34, Issue:5 Topics: Amobarbital; Anesthetics, Local; Animals; Barbiturates; Carcinoma, Hepatocellular; Cell Count; Cell Division; Culture Media; Culture Techniques; Lidocaine; Liver Neoplasms; Methohexital; Neoplasms, Experimental; Oxygen Consumption; Phenobarbital; Prilocaine; Rats; Thiopental; Time Factors; Tyrosine Transaminase	1971
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1972, Volume: 74, Issue:7 Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine	1972
Spectral studies on drug-cytochrome P-450 interaction in isolated rat liver cells. Biochemical and biophysical research communications, 1973, Dec-10, Volume: 55, Issue:3 Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Hexobarbital; Humans; Kinetics; Lidocaine; Liver; Male; Nortriptyline; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Substance-Related Disorders; Time Factors	1973
Lidocaine metabolism in normal and phenobarbital-pretreated dogs. Anesthesiology, 1972, Volume: 36, Issue:3 Topics: Acetanilides; Amines; Anesthesia, General; Animals; Biotransformation; Chromatography, Gas; Dogs; Enzyme Induction; Ethylamines; Halothane; Lidocaine; Liver; Phenobarbital; Preanesthetic Medication; Xylenes	1972
[Anticonvulsants. 5. Treatment of convulsions in the neonatal period]. Lakartidningen, 1971, Oct-18, Volume: 68 Topics: Diazepam; Electroencephalography; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Phenobarbital; Seizures	1971
Plasma lidocaine levels in patients treated with potential inducers of microsomal enzymes. Acta anaesthesiologica Scandinavica, 1970, Volume: 14, Issue:2 Topics: Adult; Anticonvulsants; Enzyme Induction; Epilepsy; Humans; Injections, Intravenous; Lidocaine; Male; Microsomes; Middle Aged; Phenobarbital	1970
Pharmacology-toxicology. Science (New York, N.Y.), 1970, May-22, Volume: 168, Issue:3934 Topics: Antidepressive Agents; Blood Pressure; Brain; Contraceptives, Oral; Cytochromes; Desipramine; Diazepam; Endoplasmic Reticulum; Histamine; Lidocaine; Liver; Methylphenidate; Methyltyrosines; National Institutes of Health (U.S.); Norepinephrine; Norethindrone; Nortriptyline; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Placenta; Progesterone; Smoking; United States	1970
A comparison of the anticonvulsant properties of 2-diethylaminopento-4-ynoyl-2',6'-xylidide (WY 21745) with lignocaine, phenytoin, phenobarbitone and trimethadione. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:2 Topics: Anesthetics, Local; Animals; Anticonvulsants; Drug Antagonism; Electroshock; Lethal Dose 50; Lidocaine; Mice; Oxazoles; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione	1971
Barbiturates: active form and site of action at node of Ranvier sodium channels. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1 Topics: Animals; Anions; Axons; Barbiturates; Binding Sites; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Lidocaine; Phenobarbital; Rana catesbeiana; Ranvier's Nodes; Sodium; Xenopus laevis	1981
Lidocaine removal during resin hemoperfusion for phenobarbital intoxication. Artificial organs, 1984, Volume: 8, Issue:2 Topics: Female; Hemoperfusion; Humans; Ion Exchange Resins; Lidocaine; Middle Aged; Phenobarbital; Polystyrenes; Polyvinyls	1984
Status epilepticus. Pediatric clinics of North America, 1980, Volume: 27, Issue:3 Topics: Anesthesia, General; Child; Child, Preschool; Diazepam; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy, Absence; Female; Humans; Infant; Lidocaine; Male; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Time Factors	1980
Treatment of status epilepticus in adults. Canadian Medical Association journal, 1983, Mar-01, Volume: 128, Issue:5 Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Critical Care; Diazepam; Electrocardiography; Electroencephalography; Female; Humans; Intubation, Intratracheal; Lidocaine; Male; Paraldehyde; Partial Pressure; Phenobarbital; Phenytoin; Respiration, Artificial; Sodium; Status Epilepticus	1983
Lidocaine metabolism and toxicity: a laboratory experiment for dental students. Journal of dental education, 1980, Volume: 44, Issue:4 Topics: Anesthesia, Dental; Anesthesiology; Animals; Carbon Tetrachloride; Lidocaine; Liver; Male; Phenobarbital; Rats; Seizures	1980
[Management of the status epilepticus]. Gaceta medica de Mexico, 1980, Volume: 116, Issue:2 Topics: Anticonvulsants; Humans; Injections, Intravenous; Lidocaine; Phenobarbital; Phenytoin; Status Epilepticus	1980
Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:2 Topics: Adult; Anesthesia, Intravenous; Anesthesia, Spinal; Crack Cocaine; Female; Humans; Hypertension; Ketamine; Lidocaine; Phenobarbital; Pulmonary Edema; Substance-Related Disorders; Tachycardia	1993
GI cocktail. Annals of emergency medicine, 1996, Volume: 28, Issue:1 Topics: Anesthetics, Local; Antacids; Atropine; Drug Combinations; Humans; Lidocaine; Phenobarbital; Scopolamine; Treatment Outcome	1996
Effect of phenobarbital on the pharmacokinetics of lidocaine, monoethylglycinexylidide and 3-hydroxylidocaine in the rat: correlation with P450 isoform levels. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:3 Topics: Anesthetics, Local; Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Hypnotics and Sedatives; Isoenzymes; Lidocaine; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley	1997
Neonatal mydriasis: intravenous lidocaine adverse reaction. Journal of child neurology, 2002, Volume: 17, Issue:5 Topics: Anti-Arrhythmia Agents; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Infant, Newborn; Lidocaine; Male; Mydriasis; Phenobarbital; Phenytoin	2002
The difference in action on normal and convulsive cortical activity between a local anaesthetic (lidocaine) and barbiturates. Archives internationales de pharmacodynamie et de therapie, 1956, Dec-01, Volume: 108, Issue:3-4 Topics: Anesthesia, Local; Anesthetics, Local; Barbiturates; Lidocaine; Pentobarbital; Phenobarbital; Seizures	1956
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2]. Helvetica physiologica et pharmacologica acta, 1962, Volume: Suppl 12 Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental	1962
On the anticonvulsant activity of local anaesthetics. Acta pharmacologica et toxicologica, 1962, Volume: 19 Topics: Anesthesia, Local; Anesthetics, Local; Anticonvulsants; Humans; Lidocaine; Phenobarbital; Phenytoin; Tetracaine	1962
THE EFFECT OF DRUGS ON THE DURATION OF TOXIC SYMPTOMS CAUSED BY SUBLETHAL DOSES OF LOCAL ANESTHETICS. AN EXPERIMENTAL STUDY ON MICE. Acta pharmacologica et toxicologica, 1964, Volume: 21 Topics: Anesthetics; Anesthetics, Local; Barbiturates; Bemegride; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Ethionine; Iproniazid; Isoniazid; Lidocaine; Mepivacaine; Meprobamate; Mice; Nikethamide; Pentobarbital; Pharmacology; Phenobarbital; Research; Toxicology	1964
Effect of lidocaine and procaine on the electroshock seizure threshold, with a comparison of the effects of phenytoin and phenobarbital. Acta psychiatrica Scandinavica. Supplementum, 1960, Volume: 35, Issue:145 Topics: Convulsive Therapy; Electroconvulsive Therapy; Electroshock; Humans; Hydantoins; Lidocaine; Phenobarbital; Phenytoin; Procaine; Seizures	1960
Efficacy of antiepileptic drugs in patients with benign convulsions with mild gastroenteritis. Brain & development, 2004, Volume: 26, Issue:3 Topics: Anesthetics, Local; Anticonvulsants; Bromazepam; Child, Preschool; Diazepam; Female; Gastroenteritis; Humans; Infant; Lidocaine; Male; Phenobarbital; Retrospective Studies; Seizures	2004
Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates. Pharmaceutical research, 2004, Volume: 21, Issue:8 Topics: Administration, Cutaneous; Age Factors; Animals; Caffeine; Diffusion; Ear; Humans; In Vitro Techniques; Infant, Newborn; Infant, Premature; Iontophoresis; Lidocaine; Models, Animal; Permeability; Phenobarbital; Skin; Swine	2004
Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. Brain & development, 2009, Volume: 31, Issue:8 Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Encephalitis; Epilepsies, Partial; Female; Fructose; Humans; Lidocaine; Magnetic Resonance Imaging; Male; Phenobarbital; Radiography; Severity of Illness Index; Syndrome; Topiramate; Treatment Outcome	2009
Long-term neurological outcome of term-born children treated with two or more anti-epileptic drugs during the neonatal period. Early human development, 2012, Volume: 88, Issue:1 Topics: Anticonvulsants; Apgar Score; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Lidocaine; Logistic Models; Male; Midazolam; Phenobarbital; Prognosis; Risk Factors; Treatment Outcome	2012
Efficacy and safety of lidocaine for treatment of neonatal seizures. Acta paediatrica (Oslo, Norway : 1992), 2013, Volume: 102, Issue:9 Topics: Cohort Studies; Electroencephalography; Female; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Lidocaine; Male; Patient Safety; Phenobarbital; Retrospective Studies; Risk Assessment; Seizures; Severity of Illness Index; Treatment Outcome	2013
Central venous cutdown in neonates: feasibility as a bedside procedure without general anesthesia. Journal of pediatric surgery, 2013, Volume: 48, Issue:8 Topics: Administration, Oral; Anesthesia, Local; Anesthetics, Local; Catheterization, Central Venous; Chloral Hydrate; Deep Sedation; Feasibility Studies; Heart Defects, Congenital; Humans; Hypnotics and Sedatives; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Injections, Intravenous; Jugular Veins; Lidocaine; Phenobarbital; Point-of-Care Systems; Sepsis; Venous Cutdown	2013
Food for thought: atrioventricular dissociation. The American journal of medicine, 2013, Volume: 126, Issue:12 Topics: Aged; Antacids; Belladonna Alkaloids; Chest Pain; Drug Combinations; Dyspepsia; Electrocardiography; Heart Block; Humans; Lidocaine; Male; Phenobarbital; Proton Pump Inhibitors	2013