lidocaine has been researched along with nortriptyline in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 10 (32.26) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Chiang, GH; Unger, SH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Andersson, RG; Nilsson, E; Post, C; Ryrfeldt, A | 1 |
| Post, C | 1 |
| Lewis, DH; Post, C | 1 |
| Andersson, RG; Lewis, DH; Post, C; Ryrfeldt, A | 1 |
| Andersson, RG; Post, C | 1 |
| Cravey, RH; Garriott, JC; Lundberg, GD; Reynolds, PC; Shaw, RF | 1 |
| Persson, G; Siwers, B | 1 |
| Grundin, R; Moldéus, P; Orrenius, S; von Bahr, C | 1 |
| Cosmides, GJ | 1 |
| Heath, A; Löfström, B; Mårtensson, E | 1 |
| Al-Rawi, S; Gogna, N; Hussain, S | 1 |
| Akaninwor, J; Bortsov, A; Carey, ET; Cutting, H; DeLaRosa, J; Farb, D; Geller, EJ; Luo, S; McNulty, S; Merrill, P; Nackley, AG; Rapkin, A; Stirling, C; Zakroysky, P | 1 |
1 review(s) available for lidocaine and nortriptyline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for lidocaine and nortriptyline
| Article | Year |
|---|---|
Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe).
Topics: Antidepressive Agents, Tricyclic; Cytokines; Estradiol; Female; Humans; Lidocaine; MicroRNAs; Multicenter Studies as Topic; Nortriptyline; Pain; Randomized Controlled Trials as Topic; Vulvodynia | 2022 |
29 other study(ies) available for lidocaine and nortriptyline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Physico-chemical modification of lidocaine uptake in rat lung tissue.
Topics: Animals; Bupivacaine; Etidocaine; Female; Hydrogen-Ion Concentration; Lidocaine; Lung; Nortriptyline; Perfusion; Rats | 1979 |
Studies on the pharmacokinetic function of the lung with special reference to lidocaine.
Topics: Animals; Bupivacaine; Etidocaine; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Lidocaine; Lung; Models, Biological; Nortriptyline; Perfusion; Smoking; Swine | 1979 |
Displacement of nortriptyline and uptake of 14C-lidocaine in the lung after administration of 14C-lidocaine to nortriptyline intoxicated pigs.
Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Lidocaine; Lung; Nortriptyline; Spectrophotometry; Swine | 1979 |
Interaction between nortriptyline and lignocaine for uptake by lung in isolated lungs and in vivo [proceedings].
Topics: Animals; Drug Interactions; Lidocaine; Lung; Nortriptyline; Rats | 1979 |
Interactions between lidocaine, norepinephrine and nortriptyline in rat lung slices.
Topics: Animals; Binding Sites; Drug Interactions; In Vitro Techniques; Lidocaine; Lung; Norepinephrine; Nortriptyline; Rats | 1979 |
Cocaine-related death.
Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Brain Edema; Cocaine; Ethanol; Female; Forensic Medicine; Humans; Intracranial Aneurysm; Lidocaine; Male; Morphine; Nortriptyline; Phenmetrazine; Substance-Related Disorders; Suicide; Tissue Distribution | 1977 |
The risk of potentiating effect of local anaesthesia with adrenalin in patients treated with tricyclic antidepressants.
Topics: Adult; Aged; Amitriptyline; Anesthesia, Local; Blood Pressure; Drug Interactions; Epinephrine; Female; Humans; Imipramine; Lidocaine; Male; Membranes; Middle Aged; Nortriptyline; Pulse; Time Factors | 1975 |
Spectral studies on drug-cytochrome P-450 interaction in isolated rat liver cells.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Hexobarbital; Humans; Kinetics; Lidocaine; Liver; Male; Nortriptyline; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Substance-Related Disorders; Time Factors | 1973 |
Pharmacology-toxicology.
Topics: Antidepressive Agents; Blood Pressure; Brain; Contraceptives, Oral; Cytochromes; Desipramine; Diazepam; Endoplasmic Reticulum; Histamine; Lidocaine; Liver; Methylphenidate; Methyltyrosines; National Institutes of Health (U.S.); Norepinephrine; Norethindrone; Nortriptyline; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Placenta; Progesterone; Smoking; United States | 1970 |
Lidocaine and amitriptyline interaction during experimental haemoperfusion.
Topics: Amitriptyline; Animals; Brain; Dogs; Drug Interactions; Female; Hemoperfusion; Kinetics; Lidocaine; Liver; Lung; Male; Myocardial Contraction; Myocardium; Nortriptyline | 1984 |
Case reports: Palatal mucosal necrosis after administration of a palatal infiltration.
Topics: Amoxicillin; Epinephrine; Female; Humans; Lidocaine; Middle Aged; Mouth Mucosa; Necrosis; Nortriptyline; Palate; Wound Healing | 2015 |