lidocaine and metoprolol

lidocaine has been researched along with metoprolol in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (32.26)	18.7374
1990's	5 (8.06)	18.2507
2000's	25 (40.32)	29.6817
2010's	12 (19.35)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Caron, G; Ermondi, G	1
Jolivette, LJ; Ward, KW	1
Jolivette, LJ; Nagilla, R; Ward, KW	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Bard, B; Carrupt, PA; Martel, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Conradi, R; Lee, PH; Shanmugasundaram, V	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Artursson, P; Mateus, A; Matsson, P	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Aberg, G; Adler, G; Duker, G; Ek, B; Telemo, E	1
Csapo, G	1
Federman, J; Vlietstra, RE	1
Hottinger, S; Kirby, DA; Lown, B; Ravid, S	1
Edvardsson, N; Hirsch, I; Olsson, SB	2
Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB	1
Balke, CW; de Langen, CD; Levine, JH; Moore, EN; Spear, JF	1
Ambrosioni, E; Boriani, G; Boschi, S; Capucci, A; Frabetti, L; Gubelli, S; Magnani, B; Marchesini, B	1
Crewe, HK; Harlow, JR; Lennard, MS; Morris, CQ; Tucker, GT; Woods, HF	1
Gorzalka, BB; Mendelson, SD	1
Plunkett, LM; Tackett, RL	1
Gülker, H; Haverkamp, W; Hindricks, G; Thale, J	1
Lillywhite, KJ; Miners, JO; Smith, KJ; Wing, LM	1
Herlitz, J; Hjalmarson, A; Holmberg, S; Swedberg, K; Waagstein, F; Waldenström, J	1
Hess, DS; Scheinman, MM	1
Campbell, RW	1
Edvardsson, N; Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Waagstein, F; Waldenström, A	1
Johnsson, G; Jordö, L; Lundborg, P; Regårdh, CG	1
Burnham, L; Byers, JM; Conrad, KA; Finley, PR	1
Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C	1
Goadsby, PJ; Kaube, H	1
du Mée, CP; Lam, XM; Ward, CA	1
Fraudeau, C; Luck, G; Mangani, F; Vérette, E	1
Aşik, I; Gülay, I; Tulunay, M; Yörükoğlu, D	1
Baker, J; Chauhan, V; Damle, R; Fain, E; Mazuz, M; O'Neill, PG; Ross, T; Sharma, AD; Skadsen, A; Zhang, Z	1
Basvaraj, S; Dubey, B; Kumar, M; Kumar, R; Lakhotia, R; Mohanty, S	1
Hollek, A; Loskot, M; Markiewicz-Łoskot, G; Moric-Janiszewska, E; Szydłowski, L; Weglarz, L	1
Perlík, F	1
Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B	1

Reviews

3 review(s) available for lidocaine and metoprolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New antiarrhythmic drugs. American journal of surgery, 1983, Volume: 145, Issue:6 Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil	1983
[Effect of liver cirrhosis on pharmacokinetics and pharmacodynamics of drugs]. Vnitrni lekarstvi, 2013, Volume: 59, Issue:7 Topics: Analgesics; Anesthetics, Local; Anti-Arrhythmia Agents; Antihypertensive Agents; Hepatic Insufficiency; Humans; Lidocaine; Liver; Liver Cirrhosis; Metoprolol; Propranolol; Risk; Verapamil	2013

Trials

4 trial(s) available for lidocaine and metoprolol

Article	Year
Tocainide and metoprolol: an efficacious therapeutic combination in the treatment of premature ventricular beats. Clinical cardiology, 1989, Volume: 12, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Humans; Lidocaine; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Random Allocation; Tocainide	1989
Relationship between infarct size and incidence of severe ventricular arrhythmias in a double-blind trial with metoprolol in acute myocardial infarction. International journal of cardiology, 1984, Volume: 6, Issue:1 Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; L-Lactate Dehydrogenase; Lidocaine; Male; Metoprolol; Middle Aged; Myocardial Infarction; Tachycardia; Ventricular Fibrillation	1984
Pain on injection of propofol: comparison of metoprolol with lidocaine. European journal of anaesthesiology, 2003, Volume: 20, Issue:6 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Humans; Injections; Lidocaine; Metoprolol; Pain; Propofol; Time Factors	2003
Shock on T versus direct current voltage for induction of ventricular fibrillation: a randomized prospective comparison. Pacing and clinical electrophysiology : PACE, 2004, Volume: 27, Issue:1 Topics: Amiodarone; Defibrillators, Implantable; Digoxin; Electric Countershock; Female; Humans; Lidocaine; Male; Metoprolol; Middle Aged; Prospective Studies; Ventricular Fibrillation	2004

Other Studies

55 other study(ies) available for lidocaine and metoprolol

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2 Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics	2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists. Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3 Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Effects of adrenergic beta-blockers and a membrane stabilizing agent on ouabain-induced cardiac arrhythmias in anaesthetized guinea pigs. Acta pharmacologica et toxicologica, 1979, Volume: 45, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Guinea Pigs; Lidocaine; Male; Metoprolol; Ouabain; Propranolol	1979
Paroxysmal nonreentrant tachycardias due to simultaneous conduction in dual atrioventricular nodal pathways. The American journal of cardiology, 1979, Volume: 43, Issue:5 Topics: Adult; Ajmaline; Atrial Fibrillation; Atrioventricular Node; Atropine; Bundle of His; Cardiac Pacing, Artificial; Electrocardiography; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Metoprolol; Models, Biological; Tachycardia, Paroxysmal; Verapamil	1979
Series on pharmacology in practice. 2. Antiarrhythmic drug therapy. Mayo Clinic proceedings, 1979, Volume: 54, Issue:8 Topics: Anti-Arrhythmia Agents; Bretylium Compounds; Disopyramide; Humans; Lidocaine; Metoprolol; Procainamide; Propranolol; Quinidine; Verapamil	1979
Inducible monomorphic sustained ventricular tachycardia in the conscious pig. American heart journal, 1990, Volume: 119, Issue:5 Topics: Animals; Coronary Vessels; Disease Models, Animal; Heart Ventricles; Hemodynamics; Lidocaine; Ligation; Magnesium; Metoprolol; Myocardial Infarction; Procainamide; Swine; Tachycardia	1990
Effects of lidocaine, procainamide, metoprolol, digoxin and atropine on the conduction of premature ventricular beats in man. European heart journal, 1985, Volume: 6, Issue:1 Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Atropine; Cardiac Complexes, Premature; Digoxin; Electric Stimulation; Electrophysiology; Humans; Lidocaine; Male; Metoprolol; Procainamide	1985
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:5 Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metoprolol; Myocardial Contraction; Pindolol; Propranolol; Time Factors; Ventricular Fibrillation	1987
Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog. Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:6 Topics: Anesthesia; Animals; Dogs; Drug Synergism; Electrocardiography; Half-Life; Lidocaine; Metoprolol; Time Factors; Ventricular Fibrillation	1988
Histamine inhibition of mixed function oxidase activity in rat and human liver microsomes and in the isolated perfused rat liver. Biochemical pharmacology, 1989, Aug-15, Volume: 38, Issue:16 Topics: Animals; Histamine; Humans; In Vitro Techniques; Lidocaine; Male; Metoprolol; Microsomes, Liver; Mixed Function Oxygenases; Rats	1989
Stimulation of beta-adrenoceptors inhibits lordosis behavior in the female rat. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4 Topics: Animals; Estradiol; Female; Isomerism; Lidocaine; Metoprolol; Pindolol; Posture; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sexual Behavior, Animal	1988
The effects of central beta-receptor antagonism on digoxin cardiotoxicity. Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Brain; Digoxin; Dogs; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Lidocaine; Male; Metoprolol; Propanolamines; Receptors, Adrenergic, beta	1985
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion. European heart journal, 1987, Volume: 8 Suppl G Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduction System; Lidocaine; Male; Metoprolol; Myocardial Infarction; Sotalol; Ventricular Fibrillation; Verapamil	1987
Failure of 'therapeutic' doses of beta-adrenoceptor antagonists to alter the disposition of tolbutamide and lignocaine. British journal of clinical pharmacology, 1984, Volume: 18, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Proteins; Drug Interactions; Female; Humans; Lidocaine; Male; Metoprolol; Oxidation-Reduction; Propranolol; Protein Binding; Tolbutamide	1984
Acute effects of lignocaine, procainamide, metoprolol, digoxin and atropine on human myocardial refractoriness. Cardiovascular research, 1984, Volume: 18, Issue:8 Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Atropine; Digoxin; Heart; Heart Rate; Heart Ventricles; Humans; Lidocaine; Male; Metoprolol; Procainamide; Time Factors; Ventricular Function	1984
Treatment and prophylaxis of ventricular arrhythmias in acute myocardial infarction. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Arrhythmias, Cardiac; Humans; Lidocaine; Metoprolol; Myocardial Infarction; Resuscitation; Time Factors; Ventricular Fibrillation	1983
Göteborg Metoprolol Trial: effects on arrhythmias. The American journal of cardiology, 1984, Jun-25, Volume: 53, Issue:13 Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Female; Heart Arrest; Hospitalization; Humans; Lidocaine; Male; Metoprolol; Middle Aged; Myocardial Infarction; Tachycardia, Paroxysmal; Ventricular Fibrillation	1984
Pharmacokinetics of lidocaine in healthy individuals pretreated with multiple doses of metoprolol. International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:6 Topics: Adult; Blood Pressure; Drug Administration Schedule; Drug Interactions; Heart Rate; Humans; Kinetics; Lidocaine; Male; Metoprolol	1984
Lidocaine elimination: effects of metoprolol and of propranolol. Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:2 Topics: Adult; Chromatography, Gas; Drug Interactions; Heart Rate; Humans; Kinetics; Lidocaine; Male; Metoprolol; Propanolamines; Propranolol	1983
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil	1995
Anti-migraine compounds fail to modulate the propagation of cortical spreading depression in the cat. European neurology, 1994, Volume: 34, Issue:1 Topics: Analgesics; Animals; Aspirin; Cats; Cerebral Cortex; Clonazepam; Cortical Spreading Depression; Dihydroergotamine; Dizocilpine Maleate; Female; Halothane; Lidocaine; Metoprolol; Migraine Disorders; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Ultrasonography, Doppler, Transcranial; Valproic Acid	1994
Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Sep-01, Volume: 52, Issue:17 Topics: Cardiotonic Agents; Drug Interactions; Drug Stability; Heparin; Humans; Lidocaine; Metoprolol; Morphine; Nitroglycerin; Plasminogen Activators; Propranolol; Tissue Plasminogen Activator	1995
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation. Journal of chromatography. A, 1997, Feb-21, Volume: 762, Issue:1-2 Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil	1997
Salvage application of secondary blood cardioplegia in intractable ventricular fibrillation. Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:5 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Blood Gas Analysis; Cardiopulmonary Bypass; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Female; Heart Arrest, Induced; Heart Septal Defects, Atrial; Heart Valve Prosthesis Implantation; Humans; Lidocaine; Magnesium Sulfate; Metoprolol; Mitral Valve; Postoperative Complications; Retreatment; Rheumatic Heart Disease; Ventricular Fibrillation	2004
Arrhythmogenic right ventricular dysplasia:clinical study. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2007, Volume: 12, Issue:2 Topics: Adolescent; Amiodarone; Anti-Arrhythmia Agents; Arrhythmogenic Right Ventricular Dysplasia; Catheter Ablation; Combined Modality Therapy; Diagnosis, Differential; Echocardiography; Electrocardiography; Female; Humans; Lidocaine; Magnetic Resonance Imaging; Metoprolol	2007
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Oct-15, Volume: 1129 Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil	2019